https://m2.mtmt.hu/ hun 2026-05-02 15:14 JournalArticle 36380150 VALIDATED true Asboth and Sanrocco authors contributed equally to this work. 0 false 2026-04-27T09:10:15.174+0000 2025-11-03T13:00:35.532+0000 2025-10-15T07:11:38.562+0000 true 10015206 Áncsán Gizella /api/admin/10015206 Admin Áncsán Gizella (SE admin) true 10015206 2025-11-03T13:00:29.531+0000 2025-11-03T13:00:29.531+0000 2025-11-03T13:00:35.539+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Asboth, Barbara true true /api/journal/10018335 REVIEWED GENES 2073-4425 2073-4425 true false 10018335 false 10018335 true 2073-4425 2073-4425 Journal FOREIGN 16 10 1212 1212 16 2025 Background/Objectives: Cystoid macular lesion (CML) is a treatable cause of central vision loss in inherited retinal diseases (IRDs). We aimed to determine the frequency of CML in a large Hungarian IRD cohort and examine associations with causative genes. Methods: This longitudinal, retrospective, monocentric study included patients with genetically confirmed IRD identified from our database. Targeted next-generation sequencing (351-gene panel) and comprehensive ophthalmic evaluation were performed, including best-corrected visual acuity (BCVA) and spectral domain optical coherence tomography (SD-OCT). CML was defined as intraretinal hyporeflective spaces with well-defined borders visible on at least two B-scans within the SD-OCT macular volume and was categorized as cystoid macular edema (CME) or non-CME. Results: We enrolled 430 patients with genetically confirmed IRDs. CML was detected in 93 eyes of 57 patients. Mean age at OCT was 36.6 ± 18.7 years (range, 3–76); 32 were male (56.1%). Inheritance patterns were autosomal recessive in 24 (42.1%), X-linked in 19 (33.3%), and autosomal dominant in 14 (24.6%). Frequently implicated genes were RS1 (12/57), USH2A (7/57), NR2E3 (7/57), PRPF31 (4/57), RPGR (4/57), and RHO (4/57). CME predominated in retinitis pigmentosa (32/57, 56%), with mean BCVA 0.44 ± 0.29 (decimal) and central retinal thickness (CRT) 401 ± 181 µm. Non-CME CML occurred in 25/57 (44%)—notably in X-linked retinoschisis and enhanced S-cone syndrome—with BCVA 0.40 ± 0.23 and CRT 465 ± 258 µm. BCVA did not correlate with CRT (rS = 0.18). Conclusions: CML occurred in 13.2% of patients within a large Hungarian cohort of genetically confirmed IRDs. Patients with IRD—mainly RP—are at higher risk for CML. Gene therapy is promising for retinal diseases, but CMLs can compromise effectiveness. Reducing and managing CME before gene therapy corroborates retinal stability and the functional state essential for the proper delivery and penetration of corrective genes to the target cells. true 2025 true true true false true false GOLD 2026-04-27 false http://www.mdpi.com/journal/genes/ 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2 false false false false 2025-11-02T13:00:35.291+0000 Szemészeti Klinika (SE / AOK / K) 11 21 1 12 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 128118239 /api/authorship/128118239 Asboth, Barbara [Asbóth, Barbara (Orvostudomány), szerző] Szemészeti Klinika (SE / AOK / K) 1 0.083 true false false Author 10102768 /api/author/10102768 Asbóth Barbara (Orvostudomány) Asbóth Barbara true true Asboth Barbara true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128358650 /api/authorship/128358650 Sanrocco, Alessandra* 2 0.0 true false Sanrocco Alessandra true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118241 /api/authorship/128118241 Besztercei, Barbara [Besztercei, Barbara (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 3 0.083 false false false Author 10070768 /api/author/10070768 Besztercei Barbara (Szemészet) Besztercei Barbara true true Besztercei Barbara true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118242 /api/authorship/128118242 Lesch, Balazs [Lesch, Balázs (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 4 0.083 false false false Author 10025482 /api/author/10025482 Lesch Balázs (Szemészet) Lesch Balázs true 10025482 true Lesch Balazs true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118243 /api/authorship/128118243 Takacs, Agnes [Takács, Ágnes Ildikó (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 5 0.083 false false false Author 10024883 /api/author/10024883 Takács Ágnes Ildikó (Szemészet) Takács Ágnes Ildikó true 10024883 true Takacs Agnes true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118244 /api/authorship/128118244 Vamos, Rita [Vámos, Rita (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 6 0.083333336 false false false Author 10025480 /api/author/10025480 Vámos Rita (Szemészet) Vámos Rita true 10025480 true Vamos Rita true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118245 /api/authorship/128118245 Varsanyi, Balazs [Varsányi, Balázs (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 7 0.083 false false false Author 10030530 /api/author/10030530 Varsányi Balázs (Szemészet) Varsányi Balázs true 10030530 true Varsanyi Balazs true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118246 /api/authorship/128118246 Vegh, Andras [Végh, András (szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 8 0.083 false false false Author 10074437 /api/author/10074437 Végh András (szemészet) Végh András true true Vegh Andras true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118247 /api/authorship/128118247 Knezy, Krisztina [Knézy, Krisztina (szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 9 0.083 false false false Author 10031139 /api/author/10031139 Knézy Krisztina (szemészet) Knézy Krisztina true 10031139 true Knezy Krisztina true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118248 /api/authorship/128118248 Szabo, Viktoria [Szabó, Viktória (szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 10 0.083 false false false Author 10034767 /api/author/10034767 Szabó Viktória (szemészet) Szabó Viktória true 10034767 true Szabo Viktoria true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118249 /api/authorship/128118249 Nagy, Zoltan Zsolt [Nagy, Zoltán Zsolt (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 11 0.083 false false false Author 10009641 /api/author/10009641 Nagy Zoltán Zsolt (Szemészet) Nagy Zoltán Zsolt true 10009641 true Nagy Zoltan Zsolt true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 128118250 /api/authorship/128118250 Zobor, Ditta ✉ [Zobor, Annamária Ditta (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K) 12 0.083 false true true Author 10037592 /api/author/10037592 Zobor Annamária Ditta (Szemészet) Zobor Annamária Ditta true 10037592 true Zobor Ditta true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 29999110 /api/publicationidentifier/29999110 DOI: 10.3390/genes16101212 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.3390/genes16101212 https://doi.org/10.3390/genes16101212 false true PublicationIdentifier 30097564 /api/publicationidentifier/30097564 WoS: 001601585700001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001601585700001 https://www.webofscience.com/wos/woscc/full-record/001601585700001 true true PublicationIdentifier 30097563 /api/publicationidentifier/30097563 Scopus: 105020058121 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105020058121 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105020058121 true true PublicationIdentifier 30097567 /api/publicationidentifier/30097567 PubMed: 41153429 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 41153429 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=41153429&dopt=Abstract true true SjrRating 11584722 /api/sjrrating/11584722 sjr:Q2 (2025) Scopus - Genetics (clinical) GENES 2073-4425 2073-4425 47 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 2716 /api/classificationexternal/2716 Scopus - Genetics (clinical) true 2716 true Q2 DIRECT true true Reference 68973682 /api/reference/68973682 1. Sahel 2014: Clinical characteristics and current therapies for inherited retinal degenerations., Cold Spring Harb. Perspect. Med., 5, p. a017111, DOI: 10.1101/cshperspect.a017111 1 10.1101/cshperspect.a017111 false true Reference 68973683 /api/reference/68973683 2. Bennett 2016: Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: A follow-on phase 1 trial., Lancet, 388, p. 661, DOI: 10.1016/S0140-6736(16)30371-3 2 10.1016/S0140-6736(16)30371-3 false true Reference 68973684 /api/reference/68973684 3. Roepman 2008: Leber congenital amaurosis: Genes, proteins and disease mechanisms., Prog. Retin. Eye Res., 27, p. 391, DOI: 10.1016/j.preteyeres.2008.05.003 3 10.1016/j.preteyeres.2008.05.003 false true Reference 68973685 /api/reference/68973685 4. Jacobson 2012: Gene therapy for Leber congenital amaurosis caused by RPE65 mutations: Safety and efficacy in 15 children and adults followed up to 3 years., Arch. Ophthalmol., 130, p. 9, DOI: 10.1001/archophthalmol.2011.298 4 10.1001/archophthalmol.2011.298 false true Reference 68973686 /api/reference/68973686 5. Wang, X., Fang, Y., Li, J., Zhang, W., Wang, J., Lewis, R.A., and Wong, L.J. (2016). Retinal diseases caused by mutations in genes not specifically associated with the clinical diagnosis. PLoS ONE, 11., DOI: 10.1371/journal.pone.0165405 5 10.1371/journal.pone.0165405 false true Reference 68973687 /api/reference/68973687 6. Salvatore 2013: Treatment of cystic macular lesions in hereditary retinal dystrophies., Surv. Ophthalmol., 58, p. 560, DOI: 10.1016/j.survophthal.2012.11.006 6 10.1016/j.survophthal.2012.11.006 false true Reference 68973688 /api/reference/68973688 7. Mahabadi, N.A., and Khanna, Y. (2024). Neuroanatomy, Retina. StatPearls [Internet], StatPearls Publishing. 7 false true Reference 68973689 /api/reference/68973689 8. Hajali 2008: The prevalence of cystoid macular oedema in retinitis pigmentosa patients determined by optical coherence tomography., Br. J. Ophthalmol., 92, p. 1065, DOI: 10.1136/bjo.2008.138560 8 10.1136/bjo.2008.138560 false true Reference 68973690 /api/reference/68973690 9. Richards 2015: Standards and guidelines for the interpretation of sequence variants: A joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology., Genet. Med., 17, p. 405, DOI: 10.1038/gim.2015.30 9 10.1038/gim.2015.30 false true Reference 68973691 /api/reference/68973691 10. Utkus 2018: X-linked juvenile retinoschisis: Phenotypic and genetic characterization., Int. J. Ophthalmol., 11, p. 1875 10 false true Reference 68973692 /api/reference/68973692 11. Adam, M.P., Feldman, J., Mirzaa, G.M., Pagon, R.A., Wallace, S.E., and Amemiya, A. (2025). X-linked congenital retinoschisis. GeneReviews®, University of Washington. 11 false true Reference 68973693 /api/reference/68973693 12. Sauer 1997: Positional cloning of the gene associated with X-linked juvenile retinoschisis., Nat. Genet., 17, p. 164, DOI: 10.1038/ng1097-164 12 10.1038/ng1097-164 false true Reference 68973694 /api/reference/68973694 13. Gaudric 2022: Non-vasogenic cystoid maculopathies., Prog. Retin. Eye Res., 91, p. 101092, DOI: 10.1016/j.preteyeres.2022.101092 13 10.1016/j.preteyeres.2022.101092 false true Reference 68973695 /api/reference/68973695 14. Milam 2002: The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration., Proc. Natl. Acad. Sci. USA, 99, p. 473, DOI: 10.1073/pnas.022533099 14 10.1073/pnas.022533099 false true Reference 68973696 /api/reference/68973696 15. Hood 1995: Enhanced S-cone syndrome: Evidence for an abnormally large number of S cones., Vis. Res., 35, p. 1473, DOI: 10.1016/0042-6989(95)98727-Q 15 10.1016/0042-6989(95)98727-Q false true Reference 68973697 /api/reference/68973697 16. Audo 2008: Phenotypic variation in enhanced S-cone syndrome., Investig. Ophthalmol. Vis. Sci., 49, p. 2082, DOI: 10.1167/iovs.05-1629 16 10.1167/iovs.05-1629 false true Reference 68973698 /api/reference/68973698 17. Schorderet 2009: NR2E3 mutations in enhanced S-cone sensitivity syndrome (ESCS), Goldmann-Favre syndrome (GFS), clumped pigmentary retinal degeneration (CPRD), and retinitis pigmentosa (RP)., Hum. Mutat., 30, p. 1475, DOI: 10.1002/humu.21096 17 10.1002/humu.21096 false true Reference 68973699 /api/reference/68973699 18. Haider 2000: Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate., Nat. Genet., 24, p. 127, DOI: 10.1038/72777 18 10.1038/72777 false true Reference 68973700 /api/reference/68973700 19. Gabrielle, P.-H., Faivre, L., Audo, I., Zanlonghi, X., Dollfus, H., Thiadens, A.A.H.J., Zeitz, C., Mancini, G.M.S., Perdomo, Y., and Mohand-Saïd, S. (2021). Cystoid maculopathy is a frequent feature of Cohen syndrome-associated retinopathy. Sci. Rep., 11., DOI: 10.1038/s41598-021-95743-8 19 10.1038/s41598-021-95743-8 false true Reference 68973701 /api/reference/68973701 20. Strong 2017: Retinitis pigmentosa-associated cystoid macular oedema: Pathogenesis and avenues of intervention., Br. J. Ophthalmol., 101, p. 31, DOI: 10.1136/bjophthalmol-2016-309376 20 10.1136/bjophthalmol-2016-309376 false true Reference 68973702 /api/reference/68973702 21. Ganesh 2011: Macular cysts in retinal dystrophy., Curr. Opin. Ophthalmol., 22, p. 332, DOI: 10.1097/ICU.0b013e328349229e 21 10.1097/ICU.0b013e328349229e false true Reference 68973703 /api/reference/68973703 22. Hirakawa 1999: Optical coherence tomography of cystoid macular edema associated with retinitis pigmentosa., Am. J. Ophthalmol., 128, p. 185, DOI: 10.1016/S0002-9394(99)00100-2 22 10.1016/S0002-9394(99)00100-2 false true Reference 68973704 /api/reference/68973704 23. Staurenghi 2016: Correlation of SD-OCT findings and visual function in patients with retinitis pigmentosa., Graefes Arch. Clin. Exp. Ophthalmol., 254, p. 1275, DOI: 10.1007/s00417-015-3185-x 23 10.1007/s00417-015-3185-x false true Reference 68973705 /api/reference/68973705 24. Mitamura 2013: Photoreceptor impairment and restoration on optical coherence tomographic image., J. Ophthalmol., 2013, p. 518170, DOI: 10.1155/2013/518170 24 10.1155/2013/518170 false true Reference 68973706 /api/reference/68973706 25. Jia 2015: Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye., Proc. Natl. Acad. Sci. USA, 112, p. E2395, DOI: 10.1073/pnas.1500185112 25 10.1073/pnas.1500185112 false true Reference 68973707 /api/reference/68973707 26. Iovino, C., Costa, C.M., Pisani, D., Damiano, L., Di Iorio, V., Testa, F., and Simonelli, F. (2023). Clinical applications of optical coherence tomography angiography in inherited retinal diseases: An up-to-date review of the literature. J. Clin. Med., 12., DOI: 10.3390/jcm12093170 26 10.3390/jcm12093170 false true Reference 68973708 /api/reference/68973708 27. Tao 2023: Visual acuity-related outer retinal structural parameters on swept source optical coherence tomography and angiography in XLRS patients and carriers., Transl. Vis. Sci. Technol., 12, p. 7, DOI: 10.1167/tvst.12.12.7 27 10.1167/tvst.12.12.7 false true Reference 68973709 /api/reference/68973709 28. Adackapara 2008: Prevalence of cystoid macular edema and stability in OCT retinal thickness in eyes with retinitis pigmentosa during a 48-week lutein trial., Retina, 28, p. 103, DOI: 10.1097/IAE.0b013e31809862aa 28 10.1097/IAE.0b013e31809862aa false true Reference 68973710 /api/reference/68973710 29. Chen, C.L., Xiao, X., and Peng, X. (2022). Management of cystoid macular edema in retinitis pigmentosa: A systematic review and meta-analysis. Front. Med., 9., DOI: 10.3389/fmed.2022.895208 29 10.3389/fmed.2022.895208 false true Reference 68973711 /api/reference/68973711 30. Jimenez-Davila, H.J., Pacheco-Avalanche, C.R.A., and Klufas, M.A. (2022). A review of retinitis pigmentosa. Rev. Ophthalmol. 30 false true Reference 68973712 /api/reference/68973712 31. Kim 2012: Association of p.P347L in the rhodopsin gene with early-onset cystoid macular edema in patients with retinitis pigmentosa., Ophthalmic Genet., 33, p. 96, DOI: 10.3109/13816810.2011.642453 31 10.3109/13816810.2011.642453 false true Reference 68973713 /api/reference/68973713 32. Pisani, D., Korb, M., Di Iorio, V., Cantile, L., Madonna, E., Niccolò, A., Colucci, R., De Benedictis, A., Melillo, P., and Testa, F. (2024, January 5–9). Cystoid macular edema in patients with retinitis pigmentosa and its genetic association. Proceedings of the ARVO Annual Meeting, Seattle, WA, USA. 32 false true Reference 68973714 /api/reference/68973714 33. Gallo, B., Capelli, R., De Benedictis, A., Brunetti-Pierri, R., Melillo, P., Rossi, S., Testa, F., Azzolini, C., Della Corte, M., and Simonelli, F. (2016, January 25–29). Prevalence of macular abnormalities assessed by optical coherence tomography in patients with Usher syndrome. Proceedings of the ARVO Annual Meeting, Orlando, FL, USA. 33 false true Reference 68973715 /api/reference/68973715 34. Arrigo 2023: Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives., Prog. Retin. Eye Res., 92, p. 101111, DOI: 10.1016/j.preteyeres.2022.101111 34 10.1016/j.preteyeres.2022.101111 false true Reference 68973716 /api/reference/68973716 35. Bakthavatchalam 2018: Treatment of cystoid macular edema secondary to retinitis pigmentosa: A systematic review., Surv. Ophthalmol., 63, p. 329, DOI: 10.1016/j.survophthal.2017.09.009 35 10.1016/j.survophthal.2017.09.009 false true Reference 68973717 /api/reference/68973717 36. The Retinoschisis Consortium (1998). Functional implications of the spectrum of mutations found in 234 cases with X-linked juvenile retinoschisis. Hum. Mol. Genet., 7, 1185–1192., DOI: 10.1093/hmg/7.7.1185 36 10.1093/hmg/7.7.1185 false true Reference 68973718 /api/reference/68973718 37. Retinal Physician (2017, October 01). Hereditary Retinal Degenerations and Cystoid Macular Edema. Available online: https://www.retinalphysician.com/issues/2017/october/hereditary-retinal-degenerations-and-cystoid-macular-edema/. 37 false true Reference 68973719 /api/reference/68973719 38. Ruff, A., Tezel, A., and Tezel, T.H. (2022). Anatomical and Functional Correlates of Cystic Macular Edema in Retinitis Pigmentosa. PLoS ONE, 17., DOI: 10.1371/journal.pone.0276629 38 10.1371/journal.pone.0276629 false true /api/publication/36380150 Asboth Barbara et al. Cystoid Macular Lesions in Inherited Retinal Diseases: Prevalence, Characteristics, and Genetic Associations in a Hungarian Cohort. (2025) GENES 2073-4425 2073-4425 16 10<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10102768"><a href="/gui2/?type=authors&mode=browse&sel=10102768" target="_blank">Asboth Barbara (<span class="authorship-author-name">Asbóth Barbara</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sanrocco Alessandra^* </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10070768"><a href="/gui2/?type=authors&mode=browse&sel=10070768" target="_blank">Besztercei Barbara (<span class="authorship-author-name">Besztercei Barbara</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10025482"><a href="/gui2/?type=authors&mode=browse&sel=10025482" target="_blank">Lesch Balazs (<span class="authorship-author-name">Lesch Balázs</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024883"><a href="/gui2/?type=authors&mode=browse&sel=10024883" target="_blank">Takacs Agnes (<span class="authorship-author-name">Takács Ágnes Ildikó</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10025480"><a href="/gui2/?type=authors&mode=browse&sel=10025480" target="_blank">Vamos Rita (<span class="authorship-author-name">Vámos Rita</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10030530"><a href="/gui2/?type=authors&mode=browse&sel=10030530" target="_blank">Varsanyi Balazs (<span class="authorship-author-name">Varsányi Balázs</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10074437"><a href="/gui2/?type=authors&mode=browse&sel=10074437" target="_blank">Vegh Andras (<span class="authorship-author-name">Végh András</span> <span class="authorAux-mtmt"> szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10031139"><a href="/gui2/?type=authors&mode=browse&sel=10031139" target="_blank">Knezy Krisztina (<span class="authorship-author-name">Knézy Krisztina</span> <span class="authorAux-mtmt"> szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10034767"><a href="/gui2/?type=authors&mode=browse&sel=10034767" target="_blank">Szabo Viktoria (<span class="authorship-author-name">Szabó Viktória</span> <span class="authorAux-mtmt"> szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009641"><a href="/gui2/?type=authors&mode=browse&sel=10009641" target="_blank">Nagy Zoltan Zsolt (<span class="authorship-author-name">Nagy Zoltán Zsolt</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037592"><a href="/gui2/?type=authors&mode=browse&sel=10037592" target="_blank">Zobor Ditta ✉ (<span class="authorship-author-name">Zobor Annamária Ditta</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szemészeti Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36380150" target="_blank">Cystoid Macular Lesions in Inherited Retinal Diseases: Prevalence, Characteristics, and Genetic Associations in a Hungarian Cohort</a></div> <div> <span class="journal-title">GENES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2073-4425">2073-4425</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2073-4425">2073-4425</a>)</span>: <span class="journal-volume">16</span> <span class="journal-issue">10</span> <span class="page"> Paper 1212. 16 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3390/genes16101212" target="_blank" href="https://doi.org/10.3390/genes16101212"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001601585700001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001601585700001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105020058121" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105020058121"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="41153429" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=41153429&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Genetics (clinical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Genetics&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36380150</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData"></span> </div> <div class="lastModified">Utolsó módosítás: 2025.11.03. 14:00 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Asboth and Sanrocco authors contributed equally to this work.</pre> </div></div>