https://m2.mtmt.hu/ eng 2026-10-25 14:05 JournalArticle 36298812 VALIDATED true * Megosztott szerzőség 0 false 2026-10-09T16:59:02.693+0000 2026-07-08T11:50:13.838+0000 2025-08-25T10:48:30.892+0000 true 10028537 Baczkó Gabriella /api/admin/10028537 Admin Gabriella Baczkó (SZTE SZAOK admin5 Szemészeti Klinika) true 10028537 2026-07-08T11:50:09.274+0000 2026-07-08T11:50:09.274+0000 2026-07-08T11:50:14.068+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin Róbert Milánkovics (PTE ÁOK admin 4) true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType Survey paper (Journal Article) 102 true 1134514 true 1 /api/category/1 Category Scientific true 1 Mohammed, Alzahra A. true true /api/journal/10043216 REVIEWED DERMATOLOGY AND THERAPY 2193-8210 2190-9172 true false 10043216 false 10043216 true 2193-8210 2190-9172 Journal FOREIGN 15 10 3009 3024 3009 16 2025 IntroductionVitiligo, a chronic depigmenting disorder affecting 1-2% of the global population, is caused by immune-mediated melanocyte destruction. While its pathogenesis is multifactorial, the relationship between vitiligo and malignancy risk remains controversial. Some studies suggest an increased cancer risk, while others propose a potential protective effect, particularly against skin cancers. This study provides a comprehensive evaluation of malignancy risks in patients with vitiligo.MethodsThis systematic review and meta-analysis followed PRISMA 2020 guidelines and was registered with PROSPERO (CRD42023483130). A comprehensive search was conducted across Medline, EMBASE, and Cochrane databases. Studies reporting hazard ratios for malignancy incidence in patients with vitiligo were included. Data extraction and risk of bias assessment were performed using the Cochrane ROBINS-E tool.ResultsOf 7753 records identified, 6378 remained after duplicates were removed, and 12 studies were included in the final review. Quantitative analysis was performed on six studies. The combined sample comprised 3,267,951 participants, including 289,322 patients with vitiligo. Three meta-analyses were conducted for melanoma, non-melanoma skin cancer, and lymphoma. The pooled hazard ratio (HR) for lymphoma was 1.00 (95% CI 0.40-2.53), for melanoma 0.80 (95% CI 0.27-2.34), and for non-melanoma skin cancer 0.38 (95% CI 0.00-732.76), suggesting no consistent associations.ConclusionThis meta-analysis did not identify significant differences in cancer risk across the examined subgroups. While a protective effect of vitiligo against some malignancies cannot be excluded, substantial heterogeneity among studies warrants cautious interpretation. Further high-quality research is needed to clarify these associations. Funding 2056490 /api/funding/2056490 (FK138696) Funder: NRDIO false true Funding 2056491 /api/funding/2056491 (LP2024-12/2024) false true true 2025 true true true false true false GOLD 2026-10-09 true https://doi.org/10.1007/s13555-025-01520-0 4 0 4 4 0 4 4 4 3 4 4 4 4 4 0 0 4 4 4 4 0 4 4 Folyóiratcikk Journal Article 24 4 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2026 0 4 4 4 4 D1 false false false false 2025-11-17T13:36:00.444+0000 Bőr-, Nemikórtani és Bőronkológiai Klinika (SE / AOK / K); HCEMM-SE Transzlációs Dermatológiai Kutatócsoport (SE / AOK / K / BNBK); Pankreász Betegségek Intézete (SE / AOK / K); Transzlációs Medicina Intézet (PTE / ÁOK); Transzlációs Medicina Központ (SE / KSZE); Élettani Intézet (SE / AOK / I) 9 44 6 12 0 true Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 127590327 /api/authorship/127590327 Mohammed, Alzahra A. [Mohammed, Alzahra Ahmed (Dermatology), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Centre for Translational Medicine (SU / KSZE) 1 0.083 true false false Author 10100258 /api/author/10100258 Alzahra Ahmed Mohammed (Dermatology) Mohammed Alzahra Ahmed true true Mohammed Alzahra A. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590328 /api/authorship/127590328 Lengyel, Anna S. [Lengyel, Anna Sára (bőrgyógyászat), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); HCEMM-SU Translational Dermatology Research Group (SU / FM / C / DDDV); Centre for Translational Medicine (SU / KSZE) 2 0.083 false false false Author 10087211 /api/author/10087211 Anna Sára Lengyel (bőrgyógyászat) Lengyel Anna Sára true true Lengyel Anna S. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590329 /api/authorship/127590329 Meznerics, Fanni A. [Meznerics, Fanni Adél (Bőrgyógyászat), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Centre for Translational Medicine (SU / KSZE) 3 0.083 false false false Author 10079444 /api/author/10079444 Fanni Adél Meznerics (Bőrgyógyászat) Meznerics Fanni Adél true true Meznerics Fanni A. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590330 /api/authorship/127590330 Szondy, Istvan [Szondy, István (Hidradenitis supp...), author] 4 0.083333336 false false false Author 10089672 /api/author/10089672 István Szondy (Hidradenitis suppurativa korszerű kezelése) Szondy István true true Szondy Istvan true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590331 /api/authorship/127590331 Walter, Anna [Walter, Anna (Biostatisztika), author] Institute for Translational Medicine (UP / UPMS) 5 0.083333336 false false false Author 10105957 /api/author/10105957 Anna Walter (Biostatisztika) Walter Anna true true Walter Anna true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590332 /api/authorship/127590332 Nagy, Benedek 6 0.083333336 false false false Nagy Benedek true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590333 /api/authorship/127590333 Csabi, Zsofia 7 0.083333336 false false false Csabi Zsofia true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590334 /api/authorship/127590334 Banvolgyi, Andras [Bánvölgyi, András (bőrgyógyászat), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Centre for Translational Medicine (SU / KSZE) 8 0.083 false false false Author 10037621 /api/author/10037621 András Bánvölgyi (bőrgyógyászat) Bánvölgyi András true 10037621 true Banvolgyi Andras true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590335 /api/authorship/127590335 Kiss, Norbert [Kiss, Norbert (Orvostudomány), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Centre for Translational Medicine (SU / KSZE) 9 0.083 false false false Author 10054754 /api/author/10054754 Norbert Kiss (Orvostudomány) Kiss Norbert true 10054754 true Kiss Norbert true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590336 /api/authorship/127590336 Hegyi, Peter [Hegyi, Péter (Gasztroenterológia), author] Institute of Pancreatic Diseases (SU / FM / C); Centre for Translational Medicine (SU / KSZE); Institute for Translational Medicine (UP / UPMS) 10 0.083 false false false Author 10002629 /api/author/10002629 Péter Hegyi (Gasztroenterológia) Hegyi Péter true 10002629 true Hegyi Peter true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590337 /api/authorship/127590337 Kurgyis, Zsuzsanna** ✉ 11 0.083 false true true Kurgyis Zsuzsanna true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127590338 /api/authorship/127590338 Kemeny, Lajos V. ✉ [Kemény, Lajos Vince (Bőrgyógyászat, on...), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Department of Physiology (SU / FM / I); HCEMM-SU Translational Dermatology Research Group (SU / FM / C / DDDV); Centre for Translational Medicine (SU / KSZE) 12 0.083 false true true Author 10040817 /api/author/10040817 Lajos Vince Kemény (Bőrgyógyászat, onkológia) Kemény Lajos Vince true 10040817 true Kemeny Lajos V. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PublicationIdentifier 29741348 /api/publicationidentifier/29741348 DOI: 10.1007/s13555-025-01520-0 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1007/s13555-025-01520-0 https://doi.org/10.1007/s13555-025-01520-0 false true PublicationIdentifier 29741349 /api/publicationidentifier/29741349 WoS: 001551679000001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001551679000001 https://www.webofscience.com/wos/woscc/full-record/001551679000001 false true PublicationIdentifier 29746235 /api/publicationidentifier/29746235 Scopus: 105013635594 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105013635594 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105013635594 false true PublicationIdentifier 29741350 /api/publicationidentifier/29741350 PubMed: 40824517 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40824517 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40824517&dopt=Abstract false true Classification 12279 /api/classification/12279 Dermatology and venereal diseases true true Keyword 3375201 /api/keyword/3375201 [Meta-analysis] true true SjrRating 11572504 /api/sjrrating/11572504 sjr:D1 (2025) Scopus - Dermatology DERMATOLOGY AND THERAPY 2193-8210 2190-9172 7 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 2708 /api/classificationexternal/2708 Scopus - Dermatology true 2708 true D1 DIRECT true true Reference 67601223 /api/reference/67601223 1. 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Cancer Risk in Vitiligo: No Evidence of Increased Prevalence-A Systematic Review and Meta-analysis. (2025) DERMATOLOGY AND THERAPY 2193-8210 2190-9172 15 10 3009-3024<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10100258"><a href="/gui2/?type=authors&mode=browse&sel=10100258" target="_blank">Mohammed Alzahra A. (<span class="authorship-author-name">Mohammed Alzahra Ahmed</span> <span class="authorAux-mtmt"> Dermatology</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10087211"><a href="/gui2/?type=authors&mode=browse&sel=10087211" target="_blank">Lengyel Anna S. (<span class="authorship-author-name">Lengyel Anna Sára</span> <span class="authorAux-mtmt"> bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Dermatology, Dermatooncology and Venerology">DDDV</span>/HCEMM-SU Translational Dermatology Research Group; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10079444"><a href="/gui2/?type=authors&mode=browse&sel=10079444" target="_blank">Meznerics Fanni A. (<span class="authorship-author-name">Meznerics Fanni Adél</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10089672"><a href="/gui2/?type=authors&mode=browse&sel=10089672" target="_blank">Szondy Istvan (<span class="authorship-author-name">Szondy István</span> <span class="authorAux-mtmt"> Hidradenitis suppurativa korszerű kezelése</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10105957"><a href="/gui2/?type=authors&mode=browse&sel=10105957" target="_blank">Walter Anna (<span class="authorship-author-name">Walter Anna</span> <span class="authorAux-mtmt"> Biostatisztika</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Institute for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Nagy Benedek </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Csabi Zsofia </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037621"><a href="/gui2/?type=authors&mode=browse&sel=10037621" target="_blank">Banvolgyi Andras (<span class="authorship-author-name">Bánvölgyi András</span> <span class="authorAux-mtmt"> bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10054754"><a href="/gui2/?type=authors&mode=browse&sel=10054754" target="_blank">Kiss Norbert (<span class="authorship-author-name">Kiss Norbert</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002629"><a href="/gui2/?type=authors&mode=browse&sel=10002629" target="_blank">Hegyi Peter (<span class="authorship-author-name">Hegyi Péter</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Institute of Pancreatic Diseases; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine; <span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Institute for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kurgyis Zsuzsanna^** ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10040817"><a href="/gui2/?type=authors&mode=browse&sel=10040817" target="_blank">Kemeny Lajos V. ✉ (<span class="authorship-author-name">Kemény Lajos Vince</span> <span class="authorAux-mtmt"> Bőrgyógyászat, onkológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Physiology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Dermatology, Dermatooncology and Venerology">DDDV</span>/HCEMM-SU Translational Dermatology Research Group; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36298812" target="_blank">Cancer Risk in Vitiligo: No Evidence of Increased Prevalence-A Systematic Review and Meta-analysis</a></div> <div> <span class="journal-title">DERMATOLOGY AND THERAPY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2193-8210">2193-8210</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2190-9172">2190-9172</a>)</span>: <span class="journal-volume">15</span> <span class="journal-issue">10</span> <span class="page"> pp 3009-3024 </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1007/s13555-025-01520-0" target="_blank" href="https://doi.org/10.1007/s13555-025-01520-0"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001551679000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001551679000001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105013635594" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105013635594"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40824517" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40824517&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Dermatology&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 4</span> | Independent citation: 4 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 4 | Number of citations in Scopus:&nbsp;3 | WoS/Scopus assigned:&nbsp;4 | Number of citations with DOI:&nbsp;4 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36298812&sort=publishedYear,desc&sort=title"> Number of cited publications: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 36298812</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="funder"> (FK138696) Funder: NRDIO, (LP2024-12/2024) </div> <div class="lastModified">Last Modified: 2026.07.08. 13:50 Róbert Milánkovics (PTE ÁOK admin 4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: * Megosztott szerzőség</pre> </div></div>