https://m2.mtmt.hu/ eng 2026-05-25 15:39 JournalArticle 36283459 VALIDATED true Összes idézések száma a WoS-ban: 0 0 false 2026-05-24T23:50:30.353+0000 2026-01-14T14:32:42.306+0000 2025-08-08T08:04:54.970+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 2026-01-14T14:32:41.897+0000 2025-08-08T08:58:48.142+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 2025-08-08T08:58:51.457+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType 104 true 10000359 true 1 /api/category/1 Category true 1 Kolb, Christof Biventricular Cardiac Resynchronization Therapy with Atrial Sensing but No Atrial Lead: A Prospective Registry of Patients, Complications, and Therapy Responses true true /api/journal/10017543 REVIEWED true false 10017543 false 10017543 true 2077-0383 Journal FOREIGN 14 14 5009 5009 13 2025 Background/Objectives: Patients with normal sinus rhythms undergoing cardiac resynchronization therapy defibrillator (CRT-D) implantation may benefit from a novel two-lead CRT-D system (CRT-DX), which features an atrial sensing dipole integrated into the right ventricular lead. This single-arm, international, non-controlled investigation focused on the safety and clinical efficacy of CRT-DX devices in CRT-D candidates who do not require atrial pacing. Methods: Patients indicated for CRT-D implantation (resting heart rates > 40 bpm and >= 100 bpm during exercise, no second or higher-degree AV block, and no history of persistent or permanent atrial fibrillation) were enrolled across 21 sites in four European countries. The primary endpoint was the need for an additional RA lead implantation within 12 months. Secondary endpoints comprised any invasive re-intervention to the CRT-DX system or infection. Results: Among the 110 patients (mean age 62 years, 70% male), 60% had an underlying non-ischemic cardiac disease. During 12 months of follow-up, RA lead implantation was required in two patients for atrial undersensing or chronotropic incompetence (RA lead implantation-free rate: 98.2% (95% CI: 92.7-99.5%)). Atrial sensing amplitudes were stable (mean: 4.7 +/- 1.7 mV), AV-synchrony was maintained at >99%, and the median percentage of biventricular pacing exceeded 98%. The left ventricular ejection fraction improved by an absolute 14.7%. Conclusions: Using simple, clinically applicable inclusion criteria, the two-lead CRT-DX system demonstrated a low rate of subsequent RA lead implantations (1.8%) and maintained adequate RA sensing amplitudes throughout the observation period. 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false 2025-08-07T08:58:48.018+0000 Kardiológia Központ - Kardiológiai Tanszék (SE / AOK / K) 2 32 1 14 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 127496500 /api/authorship/127496500 1 0.071428575 true false true Kolb Christof true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127496501 /api/authorship/127496501 2 0.071428575 false false false Author 10012684 /api/author/10012684 Zima Endre István true 10012684 true Zima Endre true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127496502 /api/authorship/127496502 3 0.071428575 false false false Arnold Martin true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127496503 /api/authorship/127496503 4 0.071428575 false false false Fedorco Marian true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127496504 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false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127496510 /api/authorship/127496510 11 0.071428575 false false false Author 10002691 /api/author/10002691 Merkely Béla Péter true 10002691 true Merkely Bela true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127496511 /api/authorship/127496511 12 0.071428575 false false false Anneken Lars true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127496512 /api/authorship/127496512 13 0.071428575 false false false Felk Angelika true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127496513 /api/authorship/127496513 14 0.071428575 false true false Lennerz Carsten true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true OrgAuthorship 127496514 /api/authorship/127496514 15 0.0 false false false true false false AuthorshipType 30 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src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Kolb Christof ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012684"><a href="/gui2/?type=authors&mode=browse&sel=10012684" target="_blank">Zima Endre (<span class="authorship-author-name">Zima Endre István</span> <span class="authorAux-mtmt"> Aneszteziológia és intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Department of Cardiology – Heart and Vascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Arnold Martin </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Fedorco Marian </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Bonnemeier Hendrik </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Deneke Thomas </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Schumacher Burghard </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Nordbeck Peter </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Steinwender Clemens </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Storz Theresa </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002691"><a href="/gui2/?type=authors&mode=browse&sel=10002691" target="_blank">Merkely Bela (<span class="authorship-author-name">Merkely Béla Péter</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Department of Cardiology – Heart and Vascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Anneken Lars </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Felk Angelika </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Lennerz Carsten </span> </div> <div class="autype autype-29"> Collaborative Organization: <span class="author-affil">BIO REDUCE Study Investigators</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36283459" target="_blank">Biventricular Cardiac Resynchronization Therapy with Atrial Sensing but No Atrial Lead: A Prospective Registry of Patients, Complications, and Therapy Responses</a></div> <div> <span class="journal-title">JOURNAL OF CLINICAL MEDICINE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2077-0383">2077-0383</a>)</span>: <span class="journal-volume">14</span> <span class="journal-issue">14</span> <span class="page"> Paper 5009. 13 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/jcm14145009" target="_blank" href="https://doi.org/10.3390/jcm14145009"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001536767200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001536767200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105014146436" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105014146436"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40725698" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40725698&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="https://www.mdpi.com/2077-0383/14/14/5009" target="_blank" href="https://www.mdpi.com/2077-0383/14/14/5009"> Other URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 1</span> | Independent citation: 1 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 1 | Number of citations in Scopus:&nbsp;1 | WoS/Scopus assigned:&nbsp;1 | Number of citations with DOI:&nbsp;1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36283459&sort=publishedYear,desc&sort=title"> Number of cited publications: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 36283459</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Study Group ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Last Modified: 2026.01.14. 15:32 Márta Molnár-Taga (SE 4-es admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Összes idézések száma a WoS-ban: 0</pre> </div></div>