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      <abstractText>A 48-year-old male patient with a large (T3N3M0) p16 positive meso-hypopharyngeal tumor was hospitalized in our department for radiotherapy. The standard of care for this disease would have been radio-chemotherapy, but given the extent of the disease, we opted for palliative radiotherapy alone. Because of the patient’s p16 positivity, we assumed a high tumor response, so we offered the option of online adaptive radiotherapy, for the first time in our country. The patient accepted the treatment, which meant that we were able to carry it out by taking a cone-beam CT scan every day, which allowed us to redraw the target volumes and the organs to be protected, and create a new irradiation plan. The patient received a 10-fraction treatment without any significant side effects, and his existing symptoms of the disease were reduced. Due to the great improvement of the patient’s general condition and the significant regression of the target volume, we were able to complete the treatment up to the definitive dose. At the follow-up MRIs and CTs at 1, 2, 3, and 6 months, further high regression was reported in the treated region without distant metastasis. Compared to the high-fraction-dose treatment performed, we observed an excellent side effect profile based on quality of life questionnaires. We successfully completed the first online adaptive head and neck tumor treatment in Hungary. Orv Hetil. 2025; 166(32): 1265–1270. | Egy 48 éves férfi beteg nagy kiterjedésű (T3N3M0) p16-pozitív mesohypopharyngealis tumorral került osztályunkra sugárterápiás kezelésre. A betegség standard ellátása szerint radiokemoterápia lett volna szükséges, de tekintettel a betegség kiterjedésére, palliatív egyedüli sugárterápiás ellátás mellett döntöttünk. A beteg p16-pozitivitása miatt feltételeztük a nagy fokú tumorválaszt, ezért felajánlottuk neki az online adaptív sugárterápia lehetőségét, első ízben az országban. A beteg elfogadta a kezelést, ezáltal azt úgy tudtuk elvégezni, hogy mindennap készítettünk róla kúpsugaras CT-felvételt, ami alapján újra tudtuk rajzolni a céltérfogatokat és a védendő szerveket, és új besugárzási tervet készítettünk. A 10 alkalmas kezelést a beteg érdemi mellékhatás nélkül megkapta, a fennálló, betegség okozta panaszai csökkentek. A páciens általános állapotának nagymértékű javulásának köszönhetően, illetve a céltérfogat jelentős regressziója okán, a kezelését ki tudtuk egészíteni definitív dózisig. A beteg 1, 2, 3, 6 hónapos MRI- és CT-kontrolljain további nagy fokú regressziót tapasztaltunk a kezelt régióban, távoli áttét kialakulása nélkül. Az elvégzett, nagy frakciódózisú kezeléshez képest az életminőségi kérdőívek alapján kiváló mellékhatásprofilt tapasztaltunk. Sikeresen teljesítettük Magyarországon az első online adaptív kezelést egy fej-nyak tumoros betegnél. Orv Hetil. 2025; 166(32): 1265–1270.</abstractText>
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target=&quot;_blank&quot;&gt;Poósz Márton (&lt;span class=&quot;authorship-author-name&quot;&gt;Poósz Márton&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; onkológia, sugárterápia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;Országos Onkológiai Intézet&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10044386&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10044386&quot; target=&quot;_blank&quot;&gt;Major Tibor (&lt;span class=&quot;authorship-author-name&quot;&gt;Major Tibor&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; klinikai sugárfizika&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;Országos Onkológiai Intézet; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Onkológiai Tanszék&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10030572&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10030572&quot; target=&quot;_blank&quot;&gt;Ágoston Péter (&lt;span class=&quot;authorship-author-name&quot;&gt;Ágoston Péter Zoltán&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Sugárterápia, onkológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;Országos Onkológiai Intézet; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Onkológiai Tanszék&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10083674&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10083674&quot; target=&quot;_blank&quot;&gt;Hegyesi Szilvia (&lt;span class=&quot;authorship-author-name&quot;&gt;Gazdag-Hegyesi Szilvia&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Orvosfizika&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;Országos Onkológiai Intézet; &lt;span title=&quot;Budapesti Műszaki és Gazdaságtudományi Egyetem&quot;&gt;BME&lt;/span&gt;/&lt;span title=&quot;Egyetemi Habilitációs Bizottság és Doktori Tanács&quot;&gt;EHBDT&lt;/span&gt;/Fizikai Tudományok Doktori Iskola&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10013883&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10013883&quot; target=&quot;_blank&quot;&gt;Takácsi-Nagy Zoltán (&lt;span class=&quot;authorship-author-name&quot;&gt;Takácsi-Nagy Zoltán&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Sugárterápia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;Országos Onkológiai Intézet; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Onkológiai Tanszék&lt;/span&gt; &lt;/div&gt; &lt;/div&gt; &lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;36279576&quot; target=&quot;_blank&quot;&gt;Nagy kiterjedésű p16-pozitív fej-nyaki tumoros beteg online adaptív besugárzása az Országos Onkológiai Intézetben&lt;/a&gt;&lt;/div&gt; &lt;div&gt; &lt;span class=&quot;journal-title&quot;&gt;ORVOSI HETILAP&lt;/span&gt; &lt;span class=&quot;journal-issn&quot;&gt;(&lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/0030-6002&quot;&gt;0030-6002&lt;/a&gt; &lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/1788-6120&quot;&gt;1788-6120&lt;/a&gt;)&lt;/span&gt;: &lt;span class=&quot;journal-volume&quot;&gt;166&lt;/span&gt; &lt;span class=&quot;journal-issue&quot;&gt;32&lt;/span&gt; &lt;span class=&quot;page&quot;&gt; pp 1265-1270 &lt;/span&gt; &lt;span class=&quot;year&quot;&gt;(2025)&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;pub-footer&quot;&gt;  &lt;span class=&quot;language&quot; xmlns=&quot;http://www.w3.org/1999/html&quot;&gt;Nyelv: Magyar | &lt;/span&gt; &lt;span class=&quot;identifiers&quot;&gt; &lt;span class=&quot;id identifier oa_GOLD&quot; title=&quot; Gold &quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;10.1556/650.2025.33355&quot; target=&quot;_blank&quot; href=&quot;https://doi.org/10.1556/650.2025.33355&quot;&gt; DOI &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_GREEN&quot; title=&quot; Green &quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;222408&quot; target=&quot;_blank&quot; href=&quot;https://real.mtak.hu/222408&quot;&gt; REAL &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;001583619400001&quot; target=&quot;_blank&quot; href=&quot;https://www.webofscience.com/wos/woscc/full-record/001583619400001&quot;&gt; WoS &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;105013390462&quot; target=&quot;_blank&quot; href=&quot;http://www.scopus.com/record/display.url?origin=inward&amp;eid=2-s2.0-105013390462&quot;&gt; Scopus &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;40783934&quot; target=&quot;_blank&quot; href=&quot;http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=40783934&amp;dopt=Abstract&quot;&gt; PubMed &lt;/a&gt; &lt;/span&gt; &lt;/span&gt; &lt;OnlyViewableByAuthor&gt;&lt;div class=&quot;ratings&quot;&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q4&lt;/div&gt; &lt;div class=&quot;journal-subject&quot;&gt;Pszichológiai Tudományos Bizottság II. FTO PsziTB [1901-]&amp;nbsp;&amp;nbsp;&amp;nbsp;A&lt;/div&gt; &lt;div class=&quot;journal-subject&quot;&gt;Demográfiai Osztályközi Állandó Bizottság IXGJO DEM [1901-]&amp;nbsp;&amp;nbsp;&amp;nbsp;A hazai&lt;/div&gt; &lt;/div&gt;&lt;/OnlyViewableByAuthor&gt; &lt;div class=&quot;publication-citation&quot; style=&quot;margin-left: 0.5cm;&quot;&gt; &lt;span title=&quot;Nyilvános idézőközlemények összesen, említések nélkül&quot; class=&quot;citingPub-count&quot;&gt;Nyilvános idéző összesen: 1&lt;/span&gt; | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | WoS/Scopus jelölt:&amp;nbsp;1 | DOI jelölt:&amp;nbsp;1 &lt;/div&gt;   &lt;div class=&quot;publication-citation&quot;&gt; &lt;a target=&quot;_blank&quot; href=&quot;/api/publication?cond=citations.related;eq;36279576&amp;sort=publishedYear,desc&amp;sort=title&quot;&gt; Idézett közlemények száma: 4 &lt;/a&gt; &lt;/div&gt; &lt;div class=&quot;mtid&quot;&gt;&lt;span class=&quot;long-pub-mtid&quot;&gt;Közlemény: 36279576&lt;/span&gt; | &lt;span class=&quot;status-data status-VALIDATED&quot;&gt; Egyeztetett &lt;/span&gt; Forrás Idéző | &lt;span class=&quot;type-subtype&quot;&gt;Folyóiratcikk ( Szakcikk ) &lt;/span&gt; | &lt;span class=&quot;pub-category&quot;&gt;Tudományos&lt;/span&gt; | &lt;span class=&quot;publication-sourceOfData&quot;&gt;Scopus&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;special-affiliations&quot;&gt; Speciális affiliáció: Orvosi Hetilap szerkesztősége &lt;/div&gt; &lt;div class=&quot;lastModified&quot;&gt;Utolsó módosítás: 2026.02.19. 10:41 Csernyik Rita (MTMT központi admin) &lt;/div&gt; &lt;/div&gt;&lt;/div&gt;</template2>
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