https://m2.mtmt.hu/ hun 2026-05-02 17:07 JournalArticle 36268488 APPROVED true Journal Article; Review 0 false 2026-04-17T15:31:15.870+0000 2026-03-06T07:50:16.218+0000 2025-07-28T08:24:05.907+0000 true 10028537 Baczkó Gabriella /api/admin/10028537 Admin true 10028537 2026-03-06T08:12:34.142+0000 true true true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Munir, Talha Practical Management of Cardiovascular Adverse Events with BTKi Treatment in Patients with Chronic Lymphocytic Leukemia A Consensus Report by Hematologists and Cardiologists true true /api/journal/50 REVIEWED true false 50 false 50 true 0001-5792 1421-9662 Journal FOREIGN 24 2025 Cardiovascular (CV) adverse events (AEs), especially atrial fibrillation (AF) and hypertension, have been reported in patients receiving treatments for chronic lymphocytic leukemia (CLL), including Bruton's tyrosine kinase inhibitors (BTKis). Although these AEs are managed effectively in most cases and AE management guidelines exist, practical management approaches are inconsistent across regions and practices. We aimed to address these inconsistencies by developing consensus recommendations.A European expert panel was assembled comprising eight hematologists and six cardiologists. Literature analysis, expert interviews, and the Delphi method were used to gain consensus on screening, monitoring, and treatment of AF and hypertension statements.Maintaining BTKi treatment is paramount to maximize time to next treatment; for patients at high risk of progression, this can be achieved by appropriately treating hypertension and AF and adjusting the BTKi dose. Patients should be risk-stratified as low, moderate, high, or very high risk of cancer therapy-related CV toxicity and treated according to their disease status so that CLL treatment can be maintained. Patient education on symptom monitoring, home blood pressure monitoring, and electrocardiograms (baseline, every 3 months) are recommended to detect/monitor AF and hypertension. Close collaboration between hematologists and cardiologists is vital to achieve optimal patient outcomes. true true 2025 true true true false true false GREEN 2026-04-17 true http://publicatio.bibl.u-szeged.hu/37333 1 0 1 1 0 1 1 1 0 1 1 1 1 1 0 0 1 1 1 1 0 10 10 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 1 1 1 Q3 false false false false 2025-10-26T09:24:13.216+0000 Belgyógyászati Klinika (SZTE / SZAOK); Belgyógyászati és Hematológiai Klinika (SE / AOK / K); Transzfuziológiai Tanszék (SZTE / SZAOK) 2 20 3 14 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 127415275 /api/authorship/127415275 1 0.071 true false true Munir Talha true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127415276 /api/authorship/127415276 2 0.071428575 false false false Čiburienė Eglė true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127415277 /api/authorship/127415277 3 0.071428575 false false false Graklanov Vasko true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127415278 /api/authorship/127415278 4 0.071428575 false false false Gospodinova Mariana true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127415279 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0.071428575 false false false Pileckyte Regina true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127415285 /api/authorship/127415285 11 0.071 false false false Author 10024568 /api/author/10024568 Pozsonyi Zoltán true 10024568 true Pozsonyi Zoltan true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127415286 /api/authorship/127415286 12 0.071428575 false false false Slanina Miroslav true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127415287 /api/authorship/127415287 13 0.071428575 false false false Škerget Matevž true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127415288 /api/authorship/127415288 14 0.071428575 false true false Bulj Nikola true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 29655843 /api/publicationidentifier/29655843 PlainSource 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/api/publication/36268488 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Munir Talha ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Čiburienė Eglė </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Graklanov Vasko </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gospodinova Mariana </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Jakšić Ozren </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Lipar Luka </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10048283"><a href="/gui2/?type=authors&mode=browse&sel=10048283" target="_blank">Marton Imelda (<span class="authorship-author-name">Marton Imelda</span> <span class="authorAux-mtmt"> haematológia</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Szent-Györgyi Albert Orvostudományi Kar">SZAOK</span>/Belgyógyászati Klinika; <span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Szent-Györgyi Albert Orvostudományi Kar">SZAOK</span>/Transzfuziológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Panovská Anna </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Petríková Lucia </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Pileckyte Regina </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024568"><a href="/gui2/?type=authors&mode=browse&sel=10024568" target="_blank">Pozsonyi Zoltan (<span class="authorship-author-name">Pozsonyi Zoltán</span> <span class="authorAux-mtmt"> belgyógyászat, kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Slanina Miroslav </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Škerget Matevž </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Bulj Nikola </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36268488" target="_blank">Practical Management of Cardiovascular Adverse Events with BTKi Treatment in Patients with Chronic Lymphocytic Leukemia : A Consensus Report by Hematologists and Cardiologists.</a></div> <div> <span class="journal-title">ACTA HAEMATOLOGICA</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0001-5792">0001-5792</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1421-9662">1421-9662</a>)</span>: <span class="journal-volume"></span> <span class="page"> 24 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1159/000547426" target="_blank" href="https://doi.org/10.1159/000547426"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001573428900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001573428900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="105013488314" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105013488314"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="40684756" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40684756&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://www.scopus.com/inward/record.uri?eid=2-s2.0-105013488314&doi=10.1159%2F000547426&partnerID=40&md5=e8358c3fd4569c17c73d31d5bf0927ad" target="_blank" href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-105013488314&doi=10.1159%2F000547426&partnerID=40&md5=e8358c3fd4569c17c73d31d5bf0927ad"> Egyéb URL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="https://karger.com/article/doi/10.1159/000547426" target="_blank" href="https://karger.com/article/doi/10.1159/000547426"> Egyéb URL </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="37333" target="_blank" href="http://publicatio.bibl.u-szeged.hu/37333"> SZTE Publicatio </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Hematology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | WoS/Scopus jelölt:&nbsp;1 | DOI jelölt:&nbsp;1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36268488&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 10 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36268488</span> | <span class="status-data status-APPROVED"> Nyilvános </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">RIS-Egyéb</span> </div> <div class="lastModified">Utolsó módosítás: 2026.03.06. 08:50 Sághi-Keszthelyi Anna (SE_KK_Admin5_SKA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Journal Article; Review</pre> </div></div>