https://m2.mtmt.hu/ hun 2026-09-21 13:30 JournalArticle 36255295 VALIDATED true Journal Article; Review 0 false 2026-08-20T18:17:30.495+0000 2026-04-27T12:29:27.931+0000 2025-07-18T06:34:07.485+0000 true 10073300 Fazekas Tamás /api/author/10073300 Author true 2026-04-27T12:29:09.642+0000 2026-04-27T12:29:09.642+0000 2026-04-27T12:29:27.937+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Giesen, Alexander Direct Treatment of All Visible Tumour in Synchronous Oligometastatic Prostate Cancer Total Eradication of Tumour or the Full Monty Treatment. true true /api/journal/20066258 REVIEWED true false false 20066258 true 2588-9311 2588-9311 Journal FOREIGN 8 4 1203 1207 1203 5 2025 Recent advances in the management of synchronous oligometastatic prostate cancer (PC) highlight the potential of combining local and systemic therapies. However, there is growing interest in metastasis-directed therapy (MDT) in this setting. When all modalities are combined, this is referred as "total eradication of tumour" (TET) or "full monty treatment" (FMT). Retrospective studies have revealed promising outcomes with approaches such as cytoreductive radical prostatectomy or radiotherapy alongside MDT and combination systemic therapy. Multiple studies have demonstrated a significant proportion of cases with undetectable prostate-specific antigen and noncastrate testosterone, while one comparative trial (± MDT) revealed some evidence of an overall survival benefit. Results from the prospective trials indicate the feasibility and effectiveness of this intensive treatment strategy, with biochemical remission and disease-free states achieved in a significant proportion of cases. Overall, limitations persist, including a reliance on conventional imaging in all studies and the absence of long-term prospective data. Ongoing trials will provide definitive insights into the treatment efficacy and safety of TET/FMT. PATIENT SUMMARY: For patients with a new diagnosis of prostate cancer with only few metastases, cancer control results after treatment with local therapy, hormonal agents, and treatment targeted to all metastatic sites are promising. Further clinical trials of this approach with the inclusion of new scan techniques are eagerly awaited. true true INTERNATIONAL 2025 true true true false true false NONE 2026-08-20 false 5 0 5 3 0 5 5 5 3 5 5 3 3 3 2 0 5 3 5 3 0 0 0 Folyóiratcikk Journal Article 24 5 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 1 1 1 2026 0 4 2 4 2 D1 false false false false 2025-07-21T13:37:16.504+0000 Transzlációs Medicina Központ (SE / KSZE); Urológiai Klinika (SE / AOK / K) 2 7 2 9 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 127327273 /api/authorship/127327273 1 0.111 true false true Giesen Alexander true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127327274 /api/authorship/127327274 2 0.11111111 false false false De Preter Niels true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127327275 /api/authorship/127327275 3 0.111 false false false Author 10073300 /api/author/10073300 Fazekas Tamás true true Fazekas Tamás true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127327276 /api/authorship/127327276 4 0.11111111 false false false De Meerleer Gert true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127327277 /api/authorship/127327277 5 0.11111111 false false false Gandaglia Giorgio true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127327278 /api/authorship/127327278 6 0.11111111 false false false Marra Giancarlo true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127327279 /api/authorship/127327279 7 0.111 false false false Author 10094967 /api/author/10094967 Shariat Shahrokh François true true Shariat Shahrokh F true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127327280 /api/authorship/127327280 8 0.11111111 false false false Joniau Steven true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127327281 /api/authorship/127327281 9 0.11111111 false true false Rajwa Pawel true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true OrgAuthorship 127327282 /api/authorship/127327282 10 0.0 false false false true false false AuthorshipType 30 /api/authorshiptype/30 -29 true -29 true false true PublicationIdentifier 29618087 /api/publicationidentifier/29618087 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1016/j.euo.2025.04.011 https://doi.org/10.1016/j.euo.2025.04.011 false true PublicationIdentifier 30060599 /api/publicationidentifier/30060599 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001591695700001 https://www.webofscience.com/wos/woscc/full-record/001591695700001 true true PublicationIdentifier 29922329 /api/publicationidentifier/29922329 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105016529045 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105016529045 true true PublicationIdentifier 29618086 /api/publicationidentifier/29618086 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40300920 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40300920&dopt=Abstract false true Classification 12305 /api/classification/12305 true true Keyword 19309 /api/keyword/19309 true 19309 true Keyword 1030129 /api/keyword/1030129 true 1030129 true Keyword 1070036 /api/keyword/1070036 true 1070036 true Keyword 1912096 /api/keyword/1912096 true true Keyword 1944238 /api/keyword/1944238 true true Keyword 2498125 /api/keyword/2498125 true true Keyword 3889724 /api/keyword/3889724 true true Keyword 3889725 /api/keyword/3889725 true true SjrRating 11626142 /api/sjrrating/11626142 2 0.0 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2746 /api/classificationexternal/2746 true 2746 true D1 DIRECT true true /api/publication/36255295 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Giesen Alexander ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >De Preter Niels </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10073300"><a href="/gui2/?type=authors&mode=browse&sel=10073300" target="_blank">Fazekas Tamás (<span class="authorship-author-name">Fazekas Tamás</span> <span class="authorAux-mtmt"> Urológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Urológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >De Meerleer Gert </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gandaglia Giorgio </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Marra Giancarlo </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10094967"><a href="/gui2/?type=authors&mode=browse&sel=10094967" target="_blank">Shariat Shahrokh F (<span class="authorship-author-name">Shariat Shahrokh François</span> <span class="authorAux-mtmt"> Urológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Urológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Joniau Steven </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Rajwa Pawel </span> </div> <div class="autype autype-29"> Kollaborációs szervezet: <span class="author-affil">European Association of Urology Young Academic Urologists Prostate Cancer Working Group</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36255295" target="_blank">Direct Treatment of All Visible Tumour in Synchronous Oligometastatic Prostate Cancer : Total Eradication of Tumour or the Full Monty Treatment..</a></div> <div> <span class="journal-title">European Urology Oncology</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2588-9311">2588-9311</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2588-9311">2588-9311</a>)</span>: <span class="journal-volume">8</span> <span class="journal-issue">4</span> <span class="page"> pp 1203-1207 </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1016/j.euo.2025.04.011" target="_blank" href="https://doi.org/10.1016/j.euo.2025.04.011"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001591695700001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001591695700001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105016529045" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105016529045"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40300920" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40300920&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Oncology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Radiology, Nuclear Medicine and Imaging&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Surgery&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Urology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 5</span> | Független: 3 | Függő: 2 | Nem jelölt: 0 | WoS jelölt: 5 | Scopus jelölt:&nbsp;3 | WoS/Scopus jelölt:&nbsp;5 | DOI jelölt:&nbsp;5 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36255295</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData"></span> </div> <div class="lastModified">Utolsó módosítás: 2026.04.27. 14:29 Molnár-Taga Márta (SE 4-es admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Journal Article; Review</pre> </div></div>