https://m2.mtmt.hu/ eng 2026-10-25 00:01 JournalArticle 36246738 VALIDATED true * Megosztott szerzőség 0 false 2026-10-16T05:26:29.104+0000 2026-03-11T07:47:33.405+0000 2025-07-15T07:43:23.735+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin Róbert Milánkovics (PTE ÁOK admin 4) true 10039043 2026-06-18T17:17:32.861+0000 2025-10-13T08:10:54.931+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Ágnes Szalóky-Siki (SE_KK_Admin5_SZSA, admin) true Admin 10099440 /api/admin/10099440 Rita Csernyik (MTMT központi admin) Csernyik Rita true true 2026-10-16T05:25:18.399+0000 true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType Survey paper (Journal Article) 102 true 1134514 true 1 /api/category/1 Category Scientific true 1 Gutmacher, Ellay true true /api/journal/10019966 REVIEWED SCIENTIFIC REPORTS 2045-2322 true false 10019966 false 10019966 true 2045-2322 Journal FOREIGN 15 1 24815 24815 12 2025 Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related deaths. Early detection through non-invasive methods is critical for improving patient outcomes. This study investigates the association between the presence and relative abundance of Fusobacterium nucleatum (Fn) in saliva and CRC, evaluating its potential as a non-invasive biomarker. A systematic search was performed in MEDLINE, Embase, CENTRAL, and Scopus databases on November 25, 2023. Studies analyzing Fn in salivary samples from adults with CRC, colorectal polyps (CRP), or healthy individuals were included. Statistical analyses were performed using random-effects models to calculate pooled odds ratios (OR) and mean differences (MD) with 95% confidence intervals (CI). The risk of bias was assessed using the Quality in Prognosis Studies (QUIPS) tool. Of the 14,200 studies identified, twelve were included in our systematic review. Of these, eight were analyzed by meta-analysis. The results indicated no significant difference in the presence (OR 1.40; 95% CI [0.77; 2.54]; I2 = 0% [0; 71%], p = 0.215) or relative abundance (MD -0.01; 95% CI [-0.13; 0.11]; I2 = 25% [0; 69%], p = 0.851) of salivary Fn among CRC patients, compared to a combined group of CRP and healthy controls. Our findings suggest that the presence and relative abundance of salivary Fn are not associated with CRC. Funding 2055492 /api/funding/2055492 (TKP2021-EGA-23) Funder: Ministry for Innovation and Technology false true Funding 2055493 /api/funding/2055493 (Open access funding provided by Semmelweis University) false true true 2025 true true true false true false GOLD 2026-10-16 true https://doi.org/10.1038/s41598-025-07465-w 2 0 2 2 0 2 2 1 2 2 2 2 2 2 0 0 2 2 2 2 0 2 2 Folyóiratcikk Journal Article 24 2 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2026 0 2 2 2 2 Q1 A nemzetközi false 10015697 false false false 2025-07-14T08:46:06.953+0000 Biofizikai és Sugárbiológiai Intézet (SE / AOK / I); Fogászati és Szájsebészeti Oktató Intézet (SE / FOK); Orálbiológiai Tanszék (SE / FOK); Orális Diagnosztikai Tanszék (SE / FOK); Pankreász Betegségek Intézete (SE / AOK / K); Transzlációs Medicina Intézet (PTE / ÁOK); Transzlációs Medicina Központ (SE / KSZE) 8 45 7 8 0 true 10099440 Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 127263951 /api/authorship/127263951 Gutmacher, Ellay [Gutmacher, Ellay (Novel insights in...), author] Centre for Translational Medicine (SU / KSZE) 1 0.125 true false false Author 10099656 /api/author/10099656 Ellay Gutmacher (Novel insights into the oral systemic-health axis) Gutmacher Ellay true true Gutmacher Ellay true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127263952 /api/authorship/127263952 Sárai, Bálint Zsombor [Sárai, Bálint Zsombor (Fogorvostudományok), author] Centre for Translational Medicine (SU / KSZE); Department of Community Dentistry (SU / FD) 2 0.125 false false false Author 10089946 /api/author/10089946 Bálint Zsombor Sárai (Fogorvostudományok) Sárai Bálint Zsombor true true Sárai Bálint Zsombor true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127263953 /api/authorship/127263953 Martineková, Petrana [Martinekova, Petrana (Hepatology/Gastro...), author] Centre for Translational Medicine (SU / KSZE) 3 0.125 false false false Author 10086102 /api/author/10086102 Petrana Martinekova (Hepatology/Gastroenterology) Martinekova Petrana true true Martineková Petrana true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127263954 /api/authorship/127263954 Kiss-Dala, Szilvia [Kiss-Dala, Szilvia (Statisztika), author] Institute for Translational Medicine (UP / UPMS); Centre for Translational Medicine (SU / KSZE) 4 0.125 false false false Author 10094940 /api/author/10094940 Szilvia Kiss-Dala (Statisztika) Kiss-Dala Szilvia true true Kiss-Dala Szilvia true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127263955 /api/authorship/127263955 Agócs, Gergely [Agócs, Gergely (biofizika), author] Departmnet of Biophysics and Radiation Biology (SU / FM / I); Centre for Translational Medicine (SU / KSZE) 5 0.125 false false false Author 10029423 /api/author/10029423 Gergely Agócs (biofizika) Agócs Gergely true 10029423 true Agócs Gergely true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127263956 /api/authorship/127263956 Hegyi, Péter [Hegyi, Péter (Gasztroenterológia), author] Institute for Translational Medicine (UP / UPMS); Institute of Pancreatic Diseases (SU / FM / C); Centre for Translational Medicine (SU / KSZE) 6 0.125 false false false Author 10002629 /api/author/10002629 Péter Hegyi (Gasztroenterológia) Hegyi Péter true 10002629 true Hegyi Péter true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127263957 /api/authorship/127263957 Bródy, Andrea** [Bródy, Andrea (Fogorvostudomány), author] Centre for Translational Medicine (SU / KSZE); Department of Oral Diagnosics (SU / FD) 7 0.125 false true false Author 10045561 /api/author/10045561 Andrea Bródy (Fogorvostudomány) Bródy Andrea true 10045561 true Bródy Andrea true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127263958 /api/authorship/127263958 Zsembery, Ákos ✉ [Zsembery, Ákos (Élettan), author] Department of Oral Biology (SU / FD); Centre for Translational Medicine (SU / KSZE) 8 0.125 false true true Author 10015697 /api/author/10015697 Ákos Zsembery (Élettan) Zsembery Ákos true 10015697 true Zsembery Ákos true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PublicationIdentifier 29596967 /api/publicationidentifier/29596967 DOI: 10.1038/s41598-025-07465-w PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1038/s41598-025-07465-w https://doi.org/10.1038/s41598-025-07465-w false true PublicationIdentifier 29765602 /api/publicationidentifier/29765602 WoS: 001527006400039 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001527006400039 https://www.webofscience.com/wos/woscc/full-record/001527006400039 true true PublicationIdentifier 29643163 /api/publicationidentifier/29643163 Scopus: 105010504545 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105010504545 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105010504545 true true PublicationIdentifier 29596966 /api/publicationidentifier/29596966 PubMed: 40640262 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40640262 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40640262&dopt=Abstract false true Keyword 3375201 /api/keyword/3375201 [Meta-analysis] true true MtaRating 519359 /api/mtarating/519359 IX. Committee on Sociology:A nemzetközi SCIENTIFIC REPORTS 2045-2322 RatingType 10007 /api/ratingtype/10007 IX. Committee on Sociology SZTB Institute 14102 /api/institute/14102 Committee on Sociology HASSELIX SZTB [1901-] 0 false true false Szociológiai Tudományos Bizottság Committee on Sociology true 14102 true true true A nemzetközi true 19359 true MtaRating 11551161 /api/mtarating/11551161 IX. Committee on Regional Studies:B nemzetközi SCIENTIFIC REPORTS 2045-2322 RatingType 10010 /api/ratingtype/10010 IX. Committee on Regional Studies RegTB Institute 14100 /api/institute/14100 Committee on Regional Studies HASSELIX RTB [1901-] 0 false true false Regionális Tudományok Bizottsága Committee on Regional Studies true 14100 true true true B nemzetközi false true SjrRating 11736329 /api/sjrrating/11736329 sjr:Q1 (2025) Scopus - Multidisciplinary SCIENTIFIC REPORTS 2045-2322 24 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1000 /api/classificationexternal/1000 Scopus - Multidisciplinary true 1000 true Q1 DIRECT true true /api/publication/36246738 Gutmacher Ellay et al. The presence and relative abundance of salivary Fusobacterium nucleatum are not associated with colorectal cancer : a systematic review and meta-analysis. (2025) SCIENTIFIC REPORTS 2045-2322 15 1<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10099656"><a href="/gui2/?type=authors&mode=browse&sel=10099656" target="_blank">Gutmacher Ellay (<span class="authorship-author-name">Gutmacher Ellay</span> <span class="authorAux-mtmt"> Novel insights into the oral systemic-health axis</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10089946"><a href="/gui2/?type=authors&mode=browse&sel=10089946" target="_blank">Sárai Bálint Zsombor (<span class="authorship-author-name">Sárai Bálint Zsombor</span> <span class="authorAux-mtmt"> Fogorvostudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine; <span title="Semmelweis University">SU</span>/<span title="Faculty of Dentistry">FD</span>/Department of Community Dentistry</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10086102"><a href="/gui2/?type=authors&mode=browse&sel=10086102" target="_blank">Martineková Petrana (<span class="authorship-author-name">Martinekova Petrana</span> <span class="authorAux-mtmt"> Hepatology/Gastroenterology</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10094940"><a href="/gui2/?type=authors&mode=browse&sel=10094940" target="_blank">Kiss-Dala Szilvia (<span class="authorship-author-name">Kiss-Dala Szilvia</span> <span class="authorAux-mtmt"> Statisztika</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Institute for Translational Medicine; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10029423"><a href="/gui2/?type=authors&mode=browse&sel=10029423" target="_blank">Agócs Gergely (<span class="authorship-author-name">Agócs Gergely</span> <span class="authorAux-mtmt"> biofizika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Departmnet of Biophysics and Radiation Biology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002629"><a href="/gui2/?type=authors&mode=browse&sel=10002629" target="_blank">Hegyi Péter (<span class="authorship-author-name">Hegyi Péter</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Institute for Translational Medicine; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Institute of Pancreatic Diseases; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10045561"><a href="/gui2/?type=authors&mode=browse&sel=10045561" target="_blank">Bródy Andrea^** (<span class="authorship-author-name">Bródy Andrea</span> <span class="authorAux-mtmt"> Fogorvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine; <span title="Semmelweis University">SU</span>/<span title="Faculty of Dentistry">FD</span>/Department of Oral Diagnosics</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10015697"><a href="/gui2/?type=authors&mode=browse&sel=10015697" target="_blank">Zsembery Ákos ✉ (<span class="authorship-author-name">Zsembery Ákos</span> <span class="authorAux-mtmt"> Élettan</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Dentistry">FD</span>/Department of Oral Biology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36246738" target="_blank">The presence and relative abundance of salivary Fusobacterium nucleatum are not associated with colorectal cancer : a systematic review and meta-analysis</a></div> <div> <span class="journal-title">SCIENTIFIC REPORTS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2045-2322">2045-2322</a>)</span>: <span class="journal-volume">15</span> <span class="journal-issue">1</span> <span class="page"> Paper 24815. 12 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1038/s41598-025-07465-w" target="_blank" href="https://doi.org/10.1038/s41598-025-07465-w"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001527006400039" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001527006400039"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105010504545" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105010504545"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40640262" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40640262&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Multidisciplinary&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Committee on Sociology HASSELIX SZTB [1901-]&nbsp;&nbsp;&nbsp;A nemzetközi</div> <div class="journal-subject">Committee on Regional Studies HASSELIX RTB [1901-]&nbsp;&nbsp;&nbsp;B nemzetközi</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 2</span> | Independent citation: 2 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 1 | Number of citations in Scopus:&nbsp;2 | WoS/Scopus assigned:&nbsp;2 | Number of citations with DOI:&nbsp;2 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36246738&sort=publishedYear,desc&sort=title"> Number of cited publications: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 36246738</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">PubMed XML</span> </div> <div class="funder"> (TKP2021-EGA-23) Funder: Ministry for Innovation and Technology, (Open access funding provided by Semmelweis University) </div> <div class="lastModified">Last Modified: 2026.03.11. 08:47 Róbert Milánkovics (PTE ÁOK admin 4) </div> <div class="lockedBy">Centrally managed 2026.10.16. 07:25 Rita Csernyik (MTMT központi admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: * Megosztott szerzőség</pre> </div></div>