https://m2.mtmt.hu/ eng 2026-05-30 15:53 JournalArticle 36241099 VALIDATED true 0 false 2026-05-24T22:51:22.838+0000 2026-04-23T12:30:51.095+0000 2025-07-10T10:19:05.431+0000 true 10083379 Belházyné Szombathelyi Ágnes /api/admin/10083379 Admin Ágnes Belházyné Szombathelyi (SZTE admin5) true 2026-04-28T08:21:02.790+0000 2026-04-23T12:30:51.293+0000 true 10058176 Nagyné Tari Emese /api/admin/10058176 Admin Emese Nagyné Tari (SZTE admin5) true 10058176 true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Article (Journal Article) 101 true 10000059 true 1 /api/category/1 Category Scientific true 1 Kleiner, Dénes true true /api/journal/10027010 REVIEWED EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE 2047-9956 2047-9964 true false 10027010 false 10027010 true 2047-9956 2047-9964 Journal FOREIGN 33 3 213 218 213 6 2026 Database-assisted screening may help detect the risks of drug interactions, but less than 10% of flagged interactions have clinical manifestations, potentially leading to alert fatigue among healthcare providers. To address this issue, this study aimed to develop a concise framework to support the management of database-indicated interaction risks.A grounded theory approach was used to design, evaluate and develop the framework. Participants included healthcare professionals and laypersons with experience using narrow therapeutic index medications, as well as individuals recommended by them. Two focus group discussions were conducted (N1=6 and N2=5), each lasting approximately 2 hours and following the same agenda. In one case, a follow-up one-on-one interview was held because the participant indicated further insights at the end of the session.Participants identified key decision-making questions for the framework, including the evidence base for interacting drugs, severity and documentation level of the interaction, availability of safer alternatives, and the presence of confounding factors. The framework was considered useful and, following refinement, potentially suitable for clinical implementation. A key insight was that integration into healthcare curricula is essential for achieving long-term impact. Overall, the proposed tool may assist in managing interaction risks in diverse clinical scenarios and reduce alert fatigue among healthcare professionals.Although further clinical validation is needed, the framework provides a foundation for improving the management of database-detected drug interactions. Funding 2055231 /api/funding/2055231 Richter Gedeon Talentum Foundation false true Funding 2055232 /api/funding/2055232 (Excellence PhD Scholarship of Gedeon Richter) false true true NATIONAL 2025 true true true false true false GOLD 2026-05-25 true https://doi.org/10.1136/ejhpharm-2025-004478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 Q1 false false false false 2025-10-08T10:23:47.394+0000 Anatómiai, Szövet- és Fejlődéstani Intézet (SE / AOK / I); Belgyógyászati és Onkológiai Klinika (SE / AOK / K); Családorvosi Tanszék (SE / AOK / K); Egyetemi Gyógyszertár Gyógyszerügyi Szervezési ... (SE / GYTK); Integratív Idegtudományi Kutatócsoport (HRN TTK / KPI); Klinikai Gyógyszerészeti Intézet (SZTE / GYTK); Molekuláris Élettudományi Intézet (HRN TTK); Sebészeti, Transzplantációs és Gasztroenterológ... (SE / AOK / K); Transzlációs Medicina Intézet (PTE / ÁOK); Transzlációs Medicina Központ (SE / KSZE) 12 74 10 16 0 true Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 127212108 /api/authorship/127212108 Kleiner, Dénes ✉ [Kleiner, Dénes (gyógyszerész), author] University Pharmacy Department of Pharmacy Admi... (SU / FP) 1 0.063 true false true Author 10059913 /api/author/10059913 Dénes Kleiner (gyógyszerész) Kleiner Dénes true 10059913 true Kleiner Dénes true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212109 /api/authorship/127212109 Haghverdi, Faraz 2 0.0625 false false false Haghverdi Faraz true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212110 /api/authorship/127212110 Szépe, Orsolya [Szépe, Orsolya (orvosi kommunikác...), author] University Pharmacy Department of Pharmacy Admi... (SU / FP) 3 0.0625 false false false Author 10021335 /api/author/10021335 Orsolya Szépe (orvosi kommunikáció, gyógyszerészi kommunikáció, tanatológia) Szépe Orsolya true 10021335 true Szépe Orsolya true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212111 /api/authorship/127212111 Horváth, István László [Horváth, István László (gyógyszerész), author] University Pharmacy Department of Pharmacy Admi... (SU / FP); Centre for Translational Medicine (SU / KSZE) 4 0.0625 false false false Author 10079182 /api/author/10079182 István László Horváth (gyógyszerész) Horváth István László true true Horváth István László true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212112 /api/authorship/127212112 Sebők, Szilvia [Sebők, Szilvia (gyógyszerészet), author] University Pharmacy Department of Pharmacy Admi... (SU / FP) 5 0.0625 false false false Author 10060853 /api/author/10060853 Szilvia Sebők (gyógyszerészet) Sebők Szilvia true 10060853 true Sebők Szilvia true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212113 /api/authorship/127212113 Csupor, Dezső [Csupor, Dezső (Klinikai gyógysze...), author] Department of Clinical Pharmacy (SZTE / FP); Institute for Translational Medicine (UP / UPMS) 6 0.063 false false false Author 10001143 /api/author/10001143 Dezső Csupor (Klinikai gyógyszerészet; Fitokémia) Csupor Dezső true 10001143 true Csupor Dezső true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212114 /api/authorship/127212114 Horváth, András [Horváth, András Attila (neurológia), author] Anatómiai, Szövet- és Fejlődéstani Intézet (SU / FM / I); Integrative Neuroscience Research Group (KPI) 7 0.063 false false false Author 10055054 /api/author/10055054 András Attila Horváth (neurológia) Horváth András Attila true 10055054 true Horváth András true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212115 /api/authorship/127212115 Balogh, Artúr György 8 0.0625 false false false Balogh Artúr György true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212116 /api/authorship/127212116 Monostory, Katalin [Monostory, Katalin (CYP), author] Institute of Molecular Life Sciences 9 0.063 false false false Author 10014587 /api/author/10014587 Katalin Monostory (CYP) Monostory Katalin true 10014587 true Monostory Katalin true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212117 /api/authorship/127212117 Kóbori, László [Kóbori, László (Sebészet, transzp...), author] Sebészeti, Transzplantációs és Gasztroenterológ... (SU / FM / C) 10 0.0625 false false false Author 10014713 /api/author/10014713 László Kóbori (Sebészet, transzplantációs sebészet) Kóbori László true 10014713 true Kóbori László true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212118 /api/authorship/127212118 Balázs, Máté [Balázs, Máté Ádám (egészségtudomány), author] Department of Internal Medicine and Oncology (SU / FM / C) 11 0.0625 false false false Author 10051835 /api/author/10051835 Máté Ádám Balázs (egészségtudomány) Balázs Máté Ádám true 10051835 true Balázs Máté true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212119 /api/authorship/127212119 Dank, Magdolna [Dank, Magdolna (onkológia), author] Department of Internal Medicine and Oncology (SU / FM / C) 12 0.0625 false false false Author 10011481 /api/author/10011481 Magdolna Dank (onkológia) Dank Magdolna true 10011481 true Dank Magdolna true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212120 /api/authorship/127212120 Móczár, Csaba Mihály [Móczár, Csaba (Orvostudomány), author] Department of Family Medicine (SU / FM / C) 13 0.0625 false false false Author 10065441 /api/author/10065441 Csaba Móczár (Orvostudomány) Móczár Csaba true true Móczár Csaba Mihály true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212121 /api/authorship/127212121 Becze, Ádám 14 0.0625 false false false Becze Ádám true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212122 /api/authorship/127212122 Süle, András 15 0.0625 false false false Süle András true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 127212123 /api/authorship/127212123 Zelkó, Romána [Zelkó, Romána (Gyógyszertechnológia), author] University Pharmacy Department of Pharmacy Admi... (SU / FP) 16 0.0625 false true false Author 10002587 /api/author/10002587 Romána Zelkó (Gyógyszertechnológia) Zelkó Romána true 10002587 true Zelkó Romána true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PublicationIdentifier 29584443 /api/publicationidentifier/29584443 DOI: 10.1136/ejhpharm-2025-004478 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1136/ejhpharm-2025-004478 https://doi.org/10.1136/ejhpharm-2025-004478 false true PublicationIdentifier 29624384 /api/publicationidentifier/29624384 WoS: 001527897900001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001527897900001 https://www.webofscience.com/wos/woscc/full-record/001527897900001 false true PublicationIdentifier 29624385 /api/publicationidentifier/29624385 Scopus: 105010398541 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105010398541 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105010398541 false true PublicationIdentifier 29584442 /api/publicationidentifier/29584442 PubMed: 40628495 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40628495 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40628495&dopt=Abstract false true PublicationIdentifier 29674122 /api/publicationidentifier/29674122 SZTE Publicatio: 37362 SwordSource 90 /api/publicationsource/90 SZTE Publicatio PublicationSourceType 10007 /api/publicationsourcetype/10007 Repozitórium true true true SZTE Publicatio SZTE Publicatio http://publicatio.bibl.u-szeged.hu/@@@ true true 90 true GREEN true IDENTICAL 37362 http://publicatio.bibl.u-szeged.hu/37362 false true Classification 12184 /api/classification/12184 Pharmacology and pharmacy true true Keyword 1008498 /api/keyword/1008498 clinical medicine true 1008498 true Keyword 1011924 /api/keyword/1011924 Evidence-Based Medicine true 1011924 true Keyword 1038143 /api/keyword/1038143 Education, Pharmacy true 1038143 true Keyword 1342923 /api/keyword/1342923 Drug-Related Side Effects and Adverse Reactions true 1342923 true Keyword 1607968 /api/keyword/1607968 Complementary therapies true true SjrRating 11735477 /api/sjrrating/11735477 sjr:Q1 (2026) Scopus - Pharmacy EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE 2047-9956 2047-9964 12 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 3611 /api/classificationexternal/3611 Scopus - Pharmacy true 3611 true Q1 FROM_LAST_YEAR true true /api/publication/36241099 Kleiner Dénes et al. How to manage the overwhelming amount of database-detected interactions? A focus group meeting study on the management of database-detected risks of drug interactions. (2026) EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE 2047-9956 2047-9964 33 3 213-218<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10059913"><a href="/gui2/?type=authors&mode=browse&sel=10059913" target="_blank">Kleiner Dénes ✉ (<span class="authorship-author-name">Kleiner Dénes</span> <span class="authorAux-mtmt"> gyógyszerész</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Pharmacy">FP</span>/University Pharmacy Department of Pharmacy Administration</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Haghverdi Faraz </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10021335"><a href="/gui2/?type=authors&mode=browse&sel=10021335" target="_blank">Szépe Orsolya (<span class="authorship-author-name">Szépe Orsolya</span> <span class="authorAux-mtmt"> orvosi kommunikáció, gyógyszerészi kommunikáció...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Pharmacy">FP</span>/University Pharmacy Department of Pharmacy Administration</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10079182"><a href="/gui2/?type=authors&mode=browse&sel=10079182" target="_blank">Horváth István László (<span class="authorship-author-name">Horváth István László</span> <span class="authorAux-mtmt"> gyógyszerész</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Pharmacy">FP</span>/University Pharmacy Department of Pharmacy Administration; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10060853"><a href="/gui2/?type=authors&mode=browse&sel=10060853" target="_blank">Sebők Szilvia (<span class="authorship-author-name">Sebők Szilvia</span> <span class="authorAux-mtmt"> gyógyszerészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Pharmacy">FP</span>/University Pharmacy Department of Pharmacy Administration</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001143"><a href="/gui2/?type=authors&mode=browse&sel=10001143" target="_blank">Csupor Dezső (<span class="authorship-author-name">Csupor Dezső</span> <span class="authorAux-mtmt"> Klinikai gyógyszerészet; Fitokémia</span>) </a> </span> <span class="author-affil"><span title="University of Szeged">SZTE</span>/<span title="Faculty of Pharmacy">FP</span>/Department of Clinical Pharmacy; <span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Institute for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10055054"><a href="/gui2/?type=authors&mode=browse&sel=10055054" target="_blank">Horváth András (<span class="authorship-author-name">Horváth András Attila</span> <span class="authorAux-mtmt"> neurológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Anatómiai, Szövet- és Fejlődéstani Intézet; <span title="HUN-REN Research Centre for Natural Sciences">HUN-REN RCNS</span>/<span title="Institute of Cognitive Neuroscience and Psychology">KPI</span>/Integrative Neuroscience Research Group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Balogh Artúr György </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10014587"><a href="/gui2/?type=authors&mode=browse&sel=10014587" target="_blank">Monostory Katalin (<span class="authorship-author-name">Monostory Katalin</span> <span class="authorAux-mtmt"> CYP</span>) </a> </span> <span class="author-affil"><span title="HUN-REN Research Centre for Natural Sciences">HUN-REN RCNS</span>/Institute of Molecular Life Sciences</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10014713"><a href="/gui2/?type=authors&mode=browse&sel=10014713" target="_blank">Kóbori László (<span class="authorship-author-name">Kóbori László</span> <span class="authorAux-mtmt"> Sebészet, transzplantációs sebészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Sebészeti, Transzplantációs és Gasztroenterológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10051835"><a href="/gui2/?type=authors&mode=browse&sel=10051835" target="_blank">Balázs Máté (<span class="authorship-author-name">Balázs Máté Ádám</span> <span class="authorAux-mtmt"> egészségtudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Internal Medicine and Oncology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10011481"><a href="/gui2/?type=authors&mode=browse&sel=10011481" target="_blank">Dank Magdolna (<span class="authorship-author-name">Dank Magdolna</span> <span class="authorAux-mtmt"> onkológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Internal Medicine and Oncology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065441"><a href="/gui2/?type=authors&mode=browse&sel=10065441" target="_blank">Móczár Csaba Mihály (<span class="authorship-author-name">Móczár Csaba</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Family Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Becze Ádám </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Süle András </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002587"><a href="/gui2/?type=authors&mode=browse&sel=10002587" target="_blank">Zelkó Romána (<span class="authorship-author-name">Zelkó Romána</span> <span class="authorAux-mtmt"> Gyógyszertechnológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Pharmacy">FP</span>/University Pharmacy Department of Pharmacy Administration</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36241099" target="_blank">How to manage the overwhelming amount of database-detected interactions? A focus group meeting study on the management of database-detected risks of drug interactions</a></div> <div> <span class="journal-title">EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-9956">2047-9956</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-9964">2047-9964</a>)</span>: <span class="journal-volume">33</span> <span class="journal-issue">3</span> <span class="page"> pp 213-218 </span> <span class="year">(2026)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1136/ejhpharm-2025-004478" target="_blank" href="https://doi.org/10.1136/ejhpharm-2025-004478"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001527897900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001527897900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105010398541" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105010398541"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40628495" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40628495&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="37362" target="_blank" href="http://publicatio.bibl.u-szeged.hu/37362"> SZTE Publicatio </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Pharmacy&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36241099&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 36241099</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">PubMed XML</span> </div> <div class="funder"> Richter Gedeon Talentum Foundation, (Excellence PhD Scholarship of Gedeon Richter) </div> <div class="lastModified">Last Modified: 2026.04.23. 14:30 Emese Nagyné Tari (SZTE admin5) </div> </div></div>