https://m2.mtmt.hu/ hun 2026-06-08 03:44 JournalArticle 36241099 APPROVED true University Pharmacy Department of Pharmacy Administration, Semmelweis University, Budapest, Hungary Centre for Translational Medicine, Semmelweis University, Budapest, Hungary Institute of Clinical Pharmacy, University of Szeged, Szeged, Hungary Institute for Translational Medicine, University of Pécs, Pécs, Hungary Neurocognitive Research Center, Nyírő Gyula National Institute of Psychiatry and Addictology, Budapest, Hungary Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary Bajcsy-Zsilinszky Hospital and Clinic, Budapest, Hungary Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary Department of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary Department of Internal Medicine and Oncology (Division of Oncology), Semmelweis University, Budapest, Hungary Department of Family Medicine, Semmelweis University, Budapest, Hungary Department of Pharmacy, Peterfy Hospital and Clinic, Budapest, Hungary Export Date: 03 June 2026; Cited By: 0; Correspondence Address: D. Kleiner; University Pharmacy Department of Pharmacy Administration, Semmelweis University, Budapest, Hungary; email: kleiner.denes@semmelweis.hu 0 false 2026-06-06T11:41:14.584+0000 2026-06-06T11:39:52.171+0000 2025-07-10T10:19:05.431+0000 true 10083379 Belházyné Szombathelyi Ágnes /api/admin/10083379 Admin true 2026-06-06T11:39:52.427+0000 2026-06-06T11:39:52.427+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Kleiner, Dénes How to manage the overwhelming amount of database-detected interactions? A focus group meeting study on the management of database-detected risks of drug interactions true true /api/journal/10027010 REVIEWED true false 10027010 false 10027010 true 2047-9956 2047-9964 Journal FOREIGN 33 3 213 218 213 6 2026 Database-assisted screening may help detect the risks of drug interactions, but less than 10% of flagged interactions have clinical manifestations, potentially leading to alert fatigue among healthcare providers. To address this issue, this study aimed to develop a concise framework to support the management of database-indicated interaction risks.A grounded theory approach was used to design, evaluate and develop the framework. Participants included healthcare professionals and laypersons with experience using narrow therapeutic index medications, as well as individuals recommended by them. Two focus group discussions were conducted (N1=6 and N2=5), each lasting approximately 2 hours and following the same agenda. In one case, a follow-up one-on-one interview was held because the participant indicated further insights at the end of the session.Participants identified key decision-making questions for the framework, including the evidence base for interacting drugs, severity and documentation level of the interaction, availability of safer alternatives, and the presence of confounding factors. The framework was considered useful and, following refinement, potentially suitable for clinical implementation. A key insight was that integration into healthcare curricula is essential for achieving long-term impact. Overall, the proposed tool may assist in managing interaction risks in diverse clinical scenarios and reduce alert fatigue among healthcare professionals.Although further clinical validation is needed, the framework provides a foundation for improving the management of database-detected drug interactions. Funding 2055231 /api/funding/2055231 false true Funding 2055232 /api/funding/2055232 false true true NATIONAL 2025 true true true false true false GOLD 2026-06-06 true https://doi.org/10.1136/ejhpharm-2025-004478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 Q1 false false false false 2025-10-08T10:23:47.394+0000 Anatómiai, Szövet- és Fejlődéstani Intézet (SE / AOK / I); Belgyógyászati és Onkológiai Klinika (SE / AOK / K); Családorvosi Tanszék (SE / AOK / K); Egyetemi Gyógyszertár Gyógyszerügyi Szervezési ... (SE / GYTK); Integratív Idegtudományi Kutatócsoport (HRN TTK / KPI); Klinikai Gyógyszerészeti Intézet (SZTE / GYTK); Molekuláris Élettudományi Intézet (HRN TTK); Nyírő Gyula Országos Pszichiátriai és Addiktoló...; Sebészeti, Transzplantációs és Gasztroenterológ... 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1342923 /api/keyword/1342923 true 1342923 true Keyword 1607968 /api/keyword/1607968 true true SjrRating 11735477 /api/sjrrating/11735477 12 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 3611 /api/classificationexternal/3611 true 3611 true Q1 FROM_LAST_YEAR true true /api/publication/36241099 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10059913"><a href="/gui2/?type=authors&mode=browse&sel=10059913" target="_blank">Kleiner Dénes ✉ (<span class="authorship-author-name">Kleiner Dénes</span> <span class="authorAux-mtmt"> gyógyszerész</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Egyetemi Gyógyszertár Gyógyszerügyi Szervezési Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Haghverdi Faraz </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10021335"><a href="/gui2/?type=authors&mode=browse&sel=10021335" target="_blank">Szépe Orsolya (<span class="authorship-author-name">Szépe Orsolya</span> <span class="authorAux-mtmt"> orvosi kommunikáció, gyógyszerészi kommunikáció...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Egyetemi Gyógyszertár Gyógyszerügyi Szervezési Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10079182"><a href="/gui2/?type=authors&mode=browse&sel=10079182" target="_blank">Horváth István László (<span class="authorship-author-name">Horváth István László</span> <span class="authorAux-mtmt"> gyógyszerész</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Egyetemi Gyógyszertár Gyógyszerügyi Szervezési Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10060853"><a href="/gui2/?type=authors&mode=browse&sel=10060853" target="_blank">Sebők Szilvia (<span class="authorship-author-name">Sebők Szilvia</span> <span class="authorAux-mtmt"> gyógyszerészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Egyetemi Gyógyszertár Gyógyszerügyi Szervezési Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001143"><a href="/gui2/?type=authors&mode=browse&sel=10001143" target="_blank">Csupor Dezső (<span class="authorship-author-name">Csupor Dezső</span> <span class="authorAux-mtmt"> Klinikai gyógyszerészet; Fitokémia</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Klinikai Gyógyszerészeti Intézet; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10055054"><a href="/gui2/?type=authors&mode=browse&sel=10055054" target="_blank">Horváth András (<span class="authorship-author-name">Horváth András Attila</span> <span class="authorAux-mtmt"> neurológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Anatómiai, Szövet- és Fejlődéstani Intézet; <span title="HUN-REN Természettudományi Kutatóközpont">HRN TTK</span>/<span title="Kognitív Idegtudományi és Pszichológiai Intézet">KPI</span>/Integratív Idegtudományi Kutatócsoport; Nyírő Gyula Országos Pszichiátriai és Addiktológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Balogh Artúr György </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10014587"><a href="/gui2/?type=authors&mode=browse&sel=10014587" target="_blank">Monostory Katalin (<span class="authorship-author-name">Monostory Katalin</span> <span class="authorAux-mtmt"> CYP</span>) </a> </span> <span class="author-affil"><span title="HUN-REN Természettudományi Kutatóközpont">HRN TTK</span>/Molekuláris Élettudományi Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10014713"><a href="/gui2/?type=authors&mode=browse&sel=10014713" target="_blank">Kóbori László (<span class="authorship-author-name">Kóbori László</span> <span class="authorAux-mtmt"> Sebészet, transzplantációs sebészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Sebészeti, Transzplantációs és Gasztroenterológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10051835"><a href="/gui2/?type=authors&mode=browse&sel=10051835" target="_blank">Balázs Máté (<span class="authorship-author-name">Balázs Máté Ádám</span> <span class="authorAux-mtmt"> egészségtudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Onkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10011481"><a href="/gui2/?type=authors&mode=browse&sel=10011481" target="_blank">Dank Magdolna (<span class="authorship-author-name">Dank Magdolna</span> <span class="authorAux-mtmt"> onkológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Onkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065441"><a href="/gui2/?type=authors&mode=browse&sel=10065441" target="_blank">Móczár Csaba Mihály (<span class="authorship-author-name">Móczár Csaba</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Családorvosi Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Becze Ádám </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Süle András </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002587"><a href="/gui2/?type=authors&mode=browse&sel=10002587" target="_blank">Zelkó Romána (<span class="authorship-author-name">Zelkó Romána</span> <span class="authorAux-mtmt"> Gyógyszertechnológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Egyetemi Gyógyszertár Gyógyszerügyi Szervezési Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36241099" target="_blank">How to manage the overwhelming amount of database-detected interactions? A focus group meeting study on the management of database-detected risks of drug interactions</a></div> <div> <span class="journal-title">EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-9956">2047-9956</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-9964">2047-9964</a>)</span>: <span class="journal-volume">33</span> <span class="journal-issue">3</span> <span class="page"> pp 213-218 </span> <span class="year">(2026)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1136/ejhpharm-2025-004478" target="_blank" href="https://doi.org/10.1136/ejhpharm-2025-004478"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001527897900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001527897900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105010398541" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105010398541"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40628495" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40628495&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="37362" target="_blank" href="http://publicatio.bibl.u-szeged.hu/37362"> SZTE Publicatio </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmacy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36241099&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36241099</span> | <span class="status-data status-APPROVED"> Nyilvános </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">PubMed XML</span> </div> <div class="funder"> Richter Gedeon Talentum Foundation, (Excellence PhD Scholarship of Gedeon Richter) </div> <div class="lastModified">Utolsó módosítás: 2026.06.06. 13:39 Döme Péter (Nyírő OPAI 4 admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: University Pharmacy Department of Pharmacy Administration, Semmelweis University, Budapest, Hungary Centre for Translational Medicine, Semmelweis University, Budapest, Hungary Institute of Clinical Pharmacy, University of Szeged, Szeged, Hungary Institute for Translational Medicine, University of Pécs, Pécs, Hungary ...</pre> </div></div>