https://m2.mtmt.hu/ eng 2026-03-17 13:33 JournalArticle 36235238 APPROVED true Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands Decision Modeling Center, Department of Epidemiology and Data Science, Amsterdam University Medical Centers, Vrije Universiteit, Amsterdam Public Health, Amsterdam, Netherlands Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, United States Department of Biostatistics, University of Washington, Seattle, WA, United States Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, United States Export Date: 08 July 2025; Cited By: 0; Correspondence Address: C.C. Brück; Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands; email: c.bruck@erasmusmc.nl; CODEN: BPRCB 0 false 2025-09-17T13:16:22.353+0000 2025-09-17T12:56:58.366+0000 2025-07-08T11:16:09.299+0000 true 10093553 Fi Tamás /api/admin/10093553 Admin true 2025-09-17T12:56:58.635+0000 2025-09-17T12:56:58.635+0000 false true true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Brück, C.C. Risk-based screening for early detection of colorectal cancer: an overview true true /api/journal/27273 REVIEWED true false 27273 false 27273 true 1521-6918 1532-1916 Journal FOREIGN in press in press 2025 Screening programs for colorectal cancer (CRC) reduce CRC incidence and mortality, while balancing benefits and harms of the population. However, benefits vary widely among individuals. Low-risk individuals may face unnecessary burdens, while high-risk individuals could benefit from more intensive screening. Risk-based screening addresses these issues by tailoring screening strategies using risk factors such as age, sex, race, ethnicity, lifestyle factors, genetic predisposition, and previous screening results. Potential benefits of risk-based screening include improved cost-effectiveness, efficient resource use and reduced unnecessary procedures. Challenges include a lack of validated risk stratification tools, data availability, healthcare capacity, and ethical considerations. Several countries started to evaluate risk-based screening programs with optimistic results. While promising, further research is necessary to address the remaining challenges. Nevertheless, risk-based screening has the potential to enhance patient experiences, optimize the balance of individual-level benefits and harms, and positively impact the overall burden and costs associated with CRC screening. © 2025 true true 2025 true true true false false false NONE 2025-09-17 false 0 0 0 0 0 0 0 0 0 0 0 0 1 1 Q1 false false false false 2025-10-06T11:18:17.762+0000 7 44 0 6 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 127175354 /api/authorship/127175354 1 0.16666667 true false false Brück C.C. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127175355 /api/authorship/127175355 2 0.16666667 false false false Mwangi L.W. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127175356 /api/authorship/127175356 3 0.16666667 false false false van Wifferen F. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127175357 /api/authorship/127175357 4 0.16666667 false false false Hsu L. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127175358 /api/authorship/127175358 5 0.16666667 false false false Thomas M. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 127175359 /api/authorship/127175359 6 0.16666667 false true false Peters U. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 29572401 /api/publicationidentifier/29572401 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true 10.1016/j.bpg.2025.102014 https://doi.org/10.1016/j.bpg.2025.102014 false true PublicationIdentifier 29572400 /api/publicationidentifier/29572400 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true 105005503377 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105005503377 false true Keyword 2591 /api/keyword/2591 true 2591 true Keyword 3118 /api/keyword/3118 true 3118 true Keyword 3122 /api/keyword/3122 true 3122 true Keyword 4212 /api/keyword/4212 true 4212 true Keyword 4301 /api/keyword/4301 true 4301 true Keyword 4537 /api/keyword/4537 true 4537 true Keyword 5322 /api/keyword/5322 true 5322 true Keyword 19809 /api/keyword/19809 true 19809 true Keyword 20139 /api/keyword/20139 true 20139 true Keyword 1029388 /api/keyword/1029388 true 1029388 true Keyword 1035868 /api/keyword/1035868 true 1035868 true Keyword 1036196 /api/keyword/1036196 true 1036196 true Keyword 1528542 /api/keyword/1528542 true true SjrRating 11583954 /api/sjrrating/11583954 35 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2715 /api/classificationexternal/2715 true 2715 true Q1 FROM_LAST_YEAR true true /api/publication/36235238 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Brück C.C. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Mwangi L.W. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >van Wifferen F. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hsu L. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Thomas M. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Peters U. </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36235238" target="_blank">Risk-based screening for early detection of colorectal cancer: an overview</a></div> <div> <span class="journal-title">BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1521-6918">1521-6918</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1532-1916">1532-1916</a>)</span>: <span class="journal-volume"></span> <span class="page"> Paper in press. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="10.1016/j.bpg.2025.102014" target="_blank" href="https://doi.org/10.1016/j.bpg.2025.102014"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="105005503377" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105005503377"> Scopus </a> </span> </span> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36235238&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 36235238</span> | <span class="status-data status-APPROVED"> Published </span> Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Last Modified: 2025.09.17. 14:56 Edit Csajbók (SE_KK_Admin5_CSE, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands Decision Modeling Center, Department of Epidemiology and Data Science, Amsterdam University Medical Centers, Vrije Universiteit, Amsterdam Public Health, Amsterdam, Netherlands Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle...</pre> </div></div>