Objectives: This study aimed to analyse the haematological parameters in relation
to subjective tinnitus. We hypothesise that abnormal haematological findings may correlate
with increased severity and chronicity of tinnitus. This research could lead to improved
diagnostic methods and more targeted treatments. Material and Methods: A total of
439 patients with primary subjective tinnitus and 274 individuals without tinnitus
were enrolled. These participants underwent comprehensive laboratory testing, which
included haematological parameters. Results: When comparing the white blood cell levels
between the tinnitus group and the control group, no statistically significant differences
were found (p = 0.743). Similarly, comparisons of red blood cell levels (p = 0.250),
haemoglobin levels (p = 0.087), and haematocrit levels (p = 0.066) also revealed no
significant differences. The platelet levels showed no significant difference between
the two groups (p = 0.782). According to a logistic regression model, lower levels
of haemoglobin (p = 0.000) and platelets (p = 0.000) significantly predicted higher
scores on the Tinnitus Handicap Inventory, indicating self-reported tinnitus severity.
Furthermore, lower haemoglobin levels were significant predictors (p = 0.04) of developing
bilateral tinnitus. Using Spearman’s correlation test, a statistically significant
negative correlation (p = 0.029) was observed between red blood cell levels and the
onset of tinnitus. The frequency of tinnitus demonstrated a significant positive correlation
with haemoglobin levels (p = 0.04) and haematocrit levels (p = 0.043). Conversely,
platelet levels showed a significant negative correlation with both tinnitus intensity
(p = 0.002) and the onset of tinnitus (p = 0.033). Conclusions: While the haematological
parameters showed no significant differences between the tinnitus and control groups,
further analyses indicated that certain parameters, such as haemoglobin and haematocrit
levels, could potentially influence tinnitus, necessitating further investigation.
