Dysregulated inflammation, oxidative stress, and protein quality control in diabetic HFpEF: unraveling mechanisms and therapeutic targets

Delalat, Simin; Sultana, Innas*; Osman, Hersh*; Sieme, Marcel*; Zhazykbayeva, Saltanat; Herwig, Melissa; Budde, Heidi; Kovács, Árpád [Kovács, Árpád (Kardiológia), author] Klinikai Fiziológiai Tanszék (UD / KardI); Kaçmaz, Mustafa; Göztepe, Eda; Borgmann, Natalie; Shahriari, Gelareh; Sasko, Benjamin; Wintrich, Jan; Haldenwang, Peter; Schmidt, Wolfgang E.; Fenske, Wiebke; Khan, Muchtiar; Jaquet, Kornelia; Mügge, Andreas; Máthé, Domokos [Máthé, Domokos (Molekuláris képal...), author] Departmnet of Biophysics and Radiation Biology (SU / FM / I); ACF-SU In Vivo Imaging (SU / FM / I / DBRB); Tóth, Viktória E. [Tóth, Viktória (Farmakológia), author] HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); Department of Pharmacology and Pharmacotherapy (SU / FM / I); Varga, Zoltán V. [Varga, Zoltán (kardiovaszkuláris...), author] HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); Department of Pharmacology and Pharmacotherapy (SU / FM / I); Ferdinandy, Péter [Ferdinandy, Péter (Farmakológia, mol...), author] HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); Department of Pharmacology and Pharmacotherapy (SU / FM / I); El-Battrawy, Ibrahim; van Heerebeek, Loek**; Hamdani, Nazha ✉ [Hamdani, Nazha (Medicine), author]

Fundings:

• (RRF-2.3.1-21-2022-00003)
• National Research, Development and Innovation Office (NKFIH) of Hungary(FK134751)
• (TKP2021-EGA-23) Funder: Ministry for Innovation and Technology