https://m2.mtmt.hu/ eng 2026-10-24 00:04 JournalArticle 36141837 VALIDATED true Department of Psychiatry, Peterfy Sandor Hospital, Budapest, 1076, Hungary Semmelweis Doctoral School, Semmelweis University, Budapest, 1085, Hungary Neurotraumatology Division, Semmelweis University, Budapest, 1081, Hungary Department of Neurosurgery and Neurotraumatology, Dr. Manninger Jenő Traumatology Institute of Budapest, Budapest, 1081, Hungary Faculty of Medicine, Semmelweis University, Budapest, 1085, Hungary Export Date: 04 June 2026; Cited By: 2; Correspondence Address: M.W. Al-Smadi; Neurotraumatology Division, Semmelweis University, Budapest, 1081, Hungary; email: smadi996@hotmail.co.uk 0 false 2026-07-26T16:07:09.656+0000 2026-07-26T16:06:03.539+0000 2025-05-14T19:46:59.779+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2026-07-26T16:05:56.429+0000 2026-07-26T16:05:56.429+0000 2026-07-26T16:06:03.705+0000 true 10084159 Balázsné Balogh Ildikó /api/admin/10084159 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Viola, Reka Effect of Cold Saline Pre-Washing on Cement Leakage in Vertebroplasty: A Novel Approach true true /api/journal/10017543 REVIEWED true false 10017543 false 10017543 true 2077-0383 Journal FOREIGN 14 8 2755 2755 8 2025 Background: Cement leakage remains a significant challenge in percutaneous vertebroplasty (PVP). Leakage can lead to serious complications, including spinal cord compression, pulmonary embolism, and nerve root irritation. While several techniques have been proposed to minimize leakage, an effective and simple solution is still needed. This study investigates the impact of pre-washing vertebral bodies with cold saline before cement injection as a potential method to reduce leakage. Methods: A retrospective analysis was conducted on patients who underwent PVP for osteoporotic vertebral compression fractures. Patients were divided into three groups: (1) conventional PVP, (2) PVP with room-temperature saline pre-injection, and (3) PVP with cold saline (4 degrees C) pre-injection. Cement leakage was assessed using intraoperative fluoroscopy and postoperative computed tomography (CT), categorized into paravertebral, intervertebral, retrograde, spinal canal, and distant venous leakage. Statistical analysis was performed to compare leakage rates among the groups. Results: A total of 262 patients with 461 treated vertebrae were analyzed. Cold saline pre-treatment significantly reduced cement leakage rates compared to conventional PVP and room-temperature saline pre-injection (p < 0.05). CT imaging detected significantly more cement extravasation than fluoroscopy (p < 0.01). The incidence of spinal canal and intervertebral leakage was lowest in the cold saline group, suggesting improved cement containment and distribution. Conclusions: Pre-washing vertebral bodies with cold saline before cement injection in PVP significantly reduces cement leakage, particularly in the spinal canal and intervertebral spaces. This simple and cost-effective approach may enhance surgical safety and improve patient outcomes. true true 2025 true true true false true false GOLD 2026-07-26 false http://www.mdpi.com/journal/jcm 2 0 2 2 0 2 2 2 0 2 2 2 2 2 0 0 2 2 2 2 0 5 5 Folyóiratcikk Journal Article 24 2 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 1 1 1 2026 0 1 1 1 1 Q2 false false false false 2025-05-13T19:51:09.326+0000 Budapesti Dr. Manninger Jenő Baleseti Központ; Budapesti Péterfy Sándor Utcai Kórház-Rendelőin...; Doktori Iskola (SE); Neurotraumatológiai Tanszéki Csoport (SE / AOK / K / TK) 6 27 4 7 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 126525076 /api/authorship/126525076 1 0.143 true false false Author 10096260 /api/author/10096260 Viola Réka true true Viola Reka true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126525077 /api/authorship/126525077 2 0.143 false false false Author 10093407 /api/author/10093407 Aslan Siran true true Aslan Siran true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126525078 /api/authorship/126525078 3 0.143 false false true Author 10082250 /api/author/10082250 Al-Smadi Mohammad Walid true true Al-Smadi Mohammad Walid true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126525079 /api/authorship/126525079 4 0.143 false false false Author 10099840 /api/author/10099840 Gati András true true Gati Andras true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126525080 /api/authorship/126525080 5 0.14285715 false false false Szilagyi Konrad true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126525081 /api/authorship/126525081 6 0.143 false false false Author 10105764 /api/author/10105764 Foglar Viktor true true Foglar Viktor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126525082 /api/authorship/126525082 7 0.143 false true false Author 10001096 /api/author/10001096 Viola Árpád true 10001096 true Viola Arpad true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 29368156 /api/publicationidentifier/29368156 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.3390/jcm14082755 https://doi.org/10.3390/jcm14082755 false true PublicationIdentifier 29368157 /api/publicationidentifier/29368157 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001476622000001 https://www.webofscience.com/wos/woscc/full-record/001476622000001 false true PublicationIdentifier 29368159 /api/publicationidentifier/29368159 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105003586815 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105003586815 false true PublicationIdentifier 29368158 /api/publicationidentifier/29368158 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40283585 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40283585&dopt=Abstract false true Classification 12258 /api/classification/12258 true true Classification 12260 /api/classification/12260 true true Keyword 1034160 /api/keyword/1034160 true 1034160 true Keyword 1034160 /api/keyword/1034160 true 1034160 true Keyword 1046276 /api/keyword/1046276 true 1046276 true Keyword 1628013 /api/keyword/1628013 true true Keyword 1966274 /api/keyword/1966274 true true Keyword 2000319 /api/keyword/2000319 true true Keyword 2016562 /api/keyword/2016562 true true SjrRating 11603514 /api/sjrrating/11603514 638 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true Q2 DIRECT true true /api/publication/36141837 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10096260"><a href="/gui2/?type=authors&mode=browse&sel=10096260" target="_blank">Viola Reka (<span class="authorship-author-name">Viola Réka</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil">Budapesti Péterfy Sándor Utcai Kórház-Rendelőintézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10093407"><a href="/gui2/?type=authors&mode=browse&sel=10093407" target="_blank">Aslan Siran (<span class="authorship-author-name">Aslan Siran</span> <span class="authorAux-mtmt"> Radiological and physiological findings after p...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/School of PhD Studies; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Traumatology">DT</span>/Section of Neurotraumatology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10082250"><a href="/gui2/?type=authors&mode=browse&sel=10082250" target="_blank">Al-Smadi Mohammad Walid ✉ (<span class="authorship-author-name">Al-Smadi Mohammad Walid</span> <span class="authorAux-mtmt"> Idegsebészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Traumatology">DT</span>/Section of Neurotraumatology; Dr. Jenő Manninger Trauma Centre Budapest</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10099840"><a href="/gui2/?type=authors&mode=browse&sel=10099840" target="_blank">Gati Andras (<span class="authorship-author-name">Gati András</span> <span class="authorAux-mtmt"> Idegsebészet</span>) </a> </span> <span class="author-affil">Dr. Jenő Manninger Trauma Centre Budapest</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szilagyi Konrad </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10105764"><a href="/gui2/?type=authors&mode=browse&sel=10105764" target="_blank">Foglar Viktor (<span class="authorship-author-name">Foglar Viktor</span> <span class="authorAux-mtmt"> neurotraumatológia</span>) </a> </span> <span class="author-affil">Dr. Jenő Manninger Trauma Centre Budapest</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001096"><a href="/gui2/?type=authors&mode=browse&sel=10001096" target="_blank">Viola Arpad (<span class="authorship-author-name">Viola Árpád</span> <span class="authorAux-mtmt"> Idegsebészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Traumatology">DT</span>/Section of Neurotraumatology; Dr. Jenő Manninger Trauma Centre Budapest</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36141837" target="_blank">Effect of Cold Saline Pre-Washing on Cement Leakage in Vertebroplasty: A Novel Approach</a></div> <div> <span class="journal-title">JOURNAL OF CLINICAL MEDICINE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2077-0383">2077-0383</a>)</span>: <span class="journal-volume">14</span> <span class="journal-issue">8</span> <span class="page"> Paper 2755. 8 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3390/jcm14082755" target="_blank" href="https://doi.org/10.3390/jcm14082755"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001476622000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001476622000001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105003586815" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105003586815"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40283585" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40283585&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 2</span> | Independent citation: 2 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 2 | WoS/Scopus assigned:&nbsp;2 | Number of citations with DOI:&nbsp;2 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36141837&sort=publishedYear,desc&sort=title"> Number of cited publications: 5 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 36141837</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Last Modified: 2026.07.26. 18:06 Ildikó Balázsné Balogh (MJ Baleseti admin4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Department of Psychiatry, Peterfy Sandor Hospital, Budapest, 1076, Hungary Semmelweis Doctoral School, Semmelweis University, Budapest, 1085, Hungary Neurotraumatology Division, Semmelweis University, Budapest, 1081, Hungary Department of Neurosurgery and Neurotraumatology, Dr. Manninger Jenő Traumatology Institute of Budap...</pre> </div></div>