https://m2.mtmt.hu/ hun 2026-09-21 04:32 JournalArticle 36136413 VALIDATED true Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary Centre for Translational Medicine, Semmelweis University, Budapest, Hungary Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary Export Date: 03 June 2026; Cited By: 6; Correspondence Address: N. Kiss; Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary; email: kiss.norbert@semmelweis.hu; CODEN: IJDEB 0 false 2026-09-13T19:57:59.648+0000 2026-06-03T03:03:08.017+0000 2025-05-13T16:29:18.572+0000 true 10080617 Varga Noémi /api/author/10080617 Author true 2026-06-18T17:17:58.804+0000 2025-09-16T08:51:21.316+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Varga, Noémi Nóra Diagnostic Accuracy of Novel Optical Imaging Techniques for Melanoma Detection: A Systematic Review and Meta‐Analysis true true /api/journal/2021 REVIEWED true false 2021 false 2021 true 0011-9059 1365-4632 Journal FOREIGN 64 10 1813 1824 1813 12 2025 The incidence of melanoma is increasing worldwide, requiring early detection to improve survival rates. Although dermoscopy is the standard non‐invasive tool for diagnosing melanoma, it relies on experience and skill. Advances in optical imaging technologies and artificial intelligence have the potential to improve diagnostic accuracy. Our objective was to compare the diagnostic accuracy of novel non‐invasive optical imaging techniques for melanoma detection. A systematic literature search was conducted in three databases (Medline, Embase, and CENTRAL) on November 15, 2023. Inclusion criteria focused on studies comparing the accuracy of optical imaging methods against histopathology. Outcomes consisted of measures of diagnostic accuracy. Random‐effects meta‐analyses were performed for each method with 95% confidence intervals to summarize all relevant effect sizes. Of the 16,239 records, 141 articles met the inclusion criteria, of which 138 articles were eligible for the meta‐analysis. Reflectance confocal microscopy (RCM) and dermoscopy combined with artificial intelligence (DSC + AI) had the highest sensitivity (0.93), with DSC + AI showing higher specificity (0.77 [0.70–0.83]) than RCM (0.749 [0.7475–0.7504]). Multispectral imaging combined with AI also showed high sensitivity (0.92 [0.82–0.97]) and relatively high specificity (0.80 [0.67–0.89]). Standalone dermoscopy exhibited balanced sensitivity (0.87 [0.84–0.90]) and specificity (0.82 [0.78–0.86]). In melanoma diagnosis, both RCM and DSC + AI can serve as second‐step optical evaluation methods for suspicious lesions following initial screening with DSC. By maintaining a strong emphasis on multimodal imaging, healthcare providers could improve early detection and outcomes for patients with melanoma. Funding 2053014 /api/funding/2053014 false true Funding 2053015 /api/funding/2053015 false true true 2025 true true true false true false GOLD 2026-09-13 true https://doi.org/10.1111/ijd.17828 7 0 7 6 2 7 7 7 6 7 7 6 6 6 1 0 7 6 7 6 0 2 2 Folyóiratcikk Journal Article 24 7 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 2 2 2 2 2026 0 5 4 5 4 Q1 false false false false 2025-08-11T16:35:10.101+0000 Bőr-, Nemikórtani és Bőronkológiai Klinika (SE / AOK / K); Pankreász Betegségek Intézete (SE / AOK / K); Transzlációs Medicina Intézet (PTE / ÁOK); Transzlációs Medicina Központ (SE / KSZE) 8 58 4 9 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 126493209 /api/authorship/126493209 1 0.111 true false false Author 10080617 /api/author/10080617 Varga Noémi true true Varga Noémi Nóra true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126493210 /api/authorship/126493210 2 0.111 false false false Author 10080623 /api/author/10080623 Gulyás Lili true true Gulyás Lili true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126493211 /api/authorship/126493211 3 0.111 false false false Author 10079444 /api/author/10079444 Meznerics Fanni Adél true true Meznerics Fanni Adél true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126493212 /api/authorship/126493212 4 0.11111111 false false false Barkovskij‐Jakobsen Katarina Sofia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126493213 /api/authorship/126493213 5 0.111 false false false Author 10055762 /api/author/10055762 Szabó Bence true 10055762 true Szabó Bence true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126493214 /api/authorship/126493214 6 0.111 false false false Author 10002629 /api/author/10002629 Hegyi Péter true 10002629 true Hegyi Péter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126493215 /api/authorship/126493215 7 0.111 false false false Author 10037621 /api/author/10037621 Bánvölgyi András true 10037621 true Bánvölgyi András true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126493216 /api/authorship/126493216 8 0.111 false false false Author 10012260 /api/author/10012260 Medvecz Márta true 10012260 true Medvecz Márta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126493217 /api/authorship/126493217 9 0.111 false true true Author 10054754 /api/author/10054754 Kiss Norbert true 10054754 true Kiss Norbert true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 29352246 /api/publicationidentifier/29352246 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1111/ijd.17828 https://doi.org/10.1111/ijd.17828 false true PublicationIdentifier 29376397 /api/publicationidentifier/29376397 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 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Reference 65801889 /api/reference/65801889 170 10.3390/jcm9051532 false true /api/publication/36136413 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10080617"><a href="/gui2/?type=authors&mode=browse&sel=10080617" target="_blank">Varga Noémi Nóra (<span class="authorship-author-name">Varga Noémi</span> <span class="authorAux-mtmt"> Orvosi tudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10080623"><a href="/gui2/?type=authors&mode=browse&sel=10080623" target="_blank">Gulyás Lili (<span class="authorship-author-name">Gulyás Lili</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10079444"><a href="/gui2/?type=authors&mode=browse&sel=10079444" target="_blank">Meznerics Fanni Adél (<span class="authorship-author-name">Meznerics Fanni Adél</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Barkovskij‐Jakobsen Katarina Sofia </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10055762"><a href="/gui2/?type=authors&mode=browse&sel=10055762" target="_blank">Szabó Bence (<span class="authorship-author-name">Szabó Bence</span> <span class="authorAux-mtmt"> Biológia, paleontológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002629"><a href="/gui2/?type=authors&mode=browse&sel=10002629" target="_blank">Hegyi Péter (<span class="authorship-author-name">Hegyi Péter</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pankreász Betegségek Intézete; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037621"><a href="/gui2/?type=authors&mode=browse&sel=10037621" target="_blank">Bánvölgyi András (<span class="authorship-author-name">Bánvölgyi András</span> <span class="authorAux-mtmt"> bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012260"><a href="/gui2/?type=authors&mode=browse&sel=10012260" target="_blank">Medvecz Márta (<span class="authorship-author-name">Medvecz Márta</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10054754"><a href="/gui2/?type=authors&mode=browse&sel=10054754" target="_blank">Kiss Norbert ✉ (<span class="authorship-author-name">Kiss Norbert</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36136413" target="_blank">Diagnostic Accuracy of Novel Optical Imaging Techniques for Melanoma Detection: A Systematic Review and Meta‐Analysis</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF DERMATOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0011-9059">0011-9059</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1365-4632">1365-4632</a>)</span>: <span class="journal-volume">64</span> <span class="journal-issue">10</span> <span class="page"> pp 1813-1824 </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1111/ijd.17828" target="_blank" href="https://doi.org/10.1111/ijd.17828"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001483245200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001483245200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105004350496" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105004350496"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40339039" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40339039&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Dermatology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 7</span> | Független: 6 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 7 | Scopus jelölt:&nbsp;6 | WoS/Scopus jelölt:&nbsp;7 | DOI jelölt:&nbsp;7 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36136413&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36136413</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (FK131916), Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009) Támogató: EFOP-VEKOP </div> <div class="lastModified">Utolsó módosítás: 2026.06.03. 05:03 Milánkovics Róbert (PTE ÁOK admin 4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary Centre for Translational Medicine, Semmelweis University, Budapest, Hungary Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary Institute of Pancreatic Diseases, Semme...</pre> </div></div>