https://m2.mtmt.hu/ hun 2026-04-30 19:54 JournalArticle 36126854 VALIDATED true 0 false 2025-12-22T10:02:18.184+0000 2025-12-22T10:00:59.438+0000 2025-05-08T15:52:17.036+0000 true 10075617 Oláh Csaba Zsolt /api/author/10075617 Author Oláh Csaba Zsolt (idegsebészet) true 2025-12-22T10:00:58.374+0000 2025-12-22T10:00:58.574+0000 true 521 Szuper Admin /api/admin/521 Admin Szuper Admin (admin) true false false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Memis Karabuga, Saliha true true /api/journal/10028447 REVIEWED POLYMERS 2073-4360 true false 10028447 false 10028447 true 2073-4360 Journal FOREIGN 17 9 1189 1189 2025 In this study, in order to overcome the fragility and cost disadvantages of PHB-based films, PHB was blended with PCL. Additionally, allyl isothiocyanate (AITC) was incorporated as an active component. The resulting PHB, PCL, and PHB/PCL composite films with/without allyl isothiocyanate (AITC) prepared via the casting method were analyzed for their physicochemical, thermal, mechanical, barrier, morphological properties and antimicrobial and antioxidant activities. While neat PHB films showed the highest tensile strength (TS) of 19.82 MPa and the lowest elongation at break (EB) of 1.13%, PHB/PCL blend films exhibited lower TS (15.34 MPa) and higher EB values (21.33%). AITC addition decreased TS significantly while showing no significant impact on EB. PHB/PCL blend films had the highest water vapor permeability (WVP) values, possibly due to their increased porosity, while neat PCL- and PHB-based films showed better oxygen and water vapor barrier properties, respectively. DSC analysis showed that PHB and PCL films had a crystalline phase, while in the case of PHB/PCL blend films, both polymers maintained their characteristic melting behaviors. The addition of AITC affected the thermal stability by increasing the melting temperature of the PHB films and decreasing the melting temperature of the PCL films. SEM analyses revealed that PHB and PHB-A films had a homogeneous structure, while irregular spherical structures and cracks were also observed in PCL and PCL-A films. The incorporation of AITC into the film samples (PHB-A, PCL-A, and PHB/PCL-A) brought remarkable antimicrobial (from 16.25 mm to 37.25 mm of inhibition zones) and antioxidant activity (from 281.85 to 286.41 mg trolox equivalent/1 g film sample, as measured by CUPRAC), while no activity was observed in the control films without AITC (PHB, PCL, and PHB/PCL). In conclusion, new AITC-activated PHB-, PCL-, and PHB/PCL-based films were successfully designated with additional functionalities and showed valuable potential to be used in active biodegradable food packaging applications. true 2025 true true true false false GOLD 2025-12-22 false http://www.mdpi.com/journal/polymers/ 0 0 0 0 0 0 0 0 0 0 0 0 2 2 Q1 false false false false 2025-08-06T15:52:34.770+0000 7 52 0 3 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 126410241 /api/authorship/126410241 Memis Karabuga, Saliha 1 0.33333334 true false false Memis Karabuga Saliha true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126410242 /api/authorship/126410242 Akman, Perihan Kubra 2 0.33333334 false false false Akman Perihan Kubra true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126410243 /api/authorship/126410243 Tornuk, Fatih 3 0.33333334 false true false Tornuk Fatih true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 29326496 /api/publicationidentifier/29326496 DOI: 10.3390/polym17091189 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.3390/polym17091189 https://doi.org/10.3390/polym17091189 false true PublicationIdentifier 30500231 /api/publicationidentifier/30500231 WoS: 001486140400001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001486140400001 https://www.webofscience.com/wos/woscc/full-record/001486140400001 false true PublicationIdentifier 29326497 /api/publicationidentifier/29326497 Egyéb URL: https://www.mdpi.com/2073-4360/17/9/1189 PlainSource 40 /api/publicationsource/40 Egyéb URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true https://www.mdpi.com/2073-4360/17/9/1189 https://www.mdpi.com/2073-4360/17/9/1189 false true SjrRating 11564814 /api/sjrrating/11564814 sjr:Q1 (2025) Scopus - Chemistry (miscellaneous) POLYMERS 2073-4360 113 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1601 /api/classificationexternal/1601 Scopus - Chemistry (miscellaneous) true 1601 true Q1 FROM_LAST_YEAR true true Reference 65711227 /api/reference/65711227 1. Lamba 2022: Recycling/reuse of plastic waste as construction material for sustainable development: A review., Environ. Sci. Pollut. Res., 29, p. 86156, DOI: 10.1007/s11356-021-16980-y 1 10.1007/s11356-021-16980-y false true Reference 65711228 /api/reference/65711228 2. 2019: Plastics recycling worldwide: Current overview and desirable changes., Field Actions Sci. Rep. J. Field Actions, 19, p. 12 2 false true Reference 65711229 /api/reference/65711229 3. Arrieta 2014: Plasticized Poly(lactic acid)–Poly(hydroxybutyrate) (PLA–PHB) Blends Incorporated with Catechin Intended for Active Food-Packaging Applications., J. Agric. Food Chem., 62, p. 10170, DOI: 10.1021/jf5029812 3 10.1021/jf5029812 false true Reference 65711230 /api/reference/65711230 4. Cavalcante 2017: Correlation between traditional techniques and TD-NMR to determine the morphology of PHB/PCL blends., Polym. Test., 58, p. 159, DOI: 10.1016/j.polymertesting.2016.11.036 4 10.1016/j.polymertesting.2016.11.036 false true Reference 65711231 /api/reference/65711231 5. Correa 2017: Improving ham shelf life with a polyhydroxybutyrate/polycaprolactone biodegradable film activated with nisin., Food Packag. Shelf Life, 11, p. 31, DOI: 10.1016/j.fpsl.2016.11.004 5 10.1016/j.fpsl.2016.11.004 false true Reference 65711232 /api/reference/65711232 6. Balart 2018: Reinforcing capability of cellulose nanocrystals obtained from pine cones in a biodegradable poly(3-hydroxybutyrate)/poly(ε-caprolactone) (PHB/PCL) thermoplastic blend., Eur. Polym. J., 104, p. 10, DOI: 10.1016/j.eurpolymj.2018.04.036 6 10.1016/j.eurpolymj.2018.04.036 false true Reference 65711233 /api/reference/65711233 7. Borisova, I., Stoilova, O., Manolova, N., and Rashkov, I. (2020). Modulating the Mechanical Properties of Electrospun PHB/PCL Materials by Using Different Types of Collectors and Heat Sealing. Polymers, 12., DOI: 10.3390/polym12030693 7 10.3390/polym12030693 false true Reference 65711234 /api/reference/65711234 8. Ferri 2016: Processing and characterization of binary poly(hydroxybutyrate) (PHB) and poly(caprolactone) (PCL) blends with improved impact properties., Polym. Bull., 73, p. 3333, DOI: 10.1007/s00289-016-1659-6 8 10.1007/s00289-016-1659-6 false true Reference 65711235 /api/reference/65711235 9. Lovera 2007: Crystallization, Morphology, and Enzymatic Degradation of Polyhydroxybutyrate/Polycaprolactone (PHB/PCL) Blends., Macromol. Chem. Phys., 208, p. 924, DOI: 10.1002/macp.200700011 9 10.1002/macp.200700011 false true Reference 65711236 /api/reference/65711236 10. Sharma 2022: Physicochemical and thermal characterization of poly (3-hydroxybutyrate-co-4-hydroxybutyrate) films incorporating thyme essential oil for active packaging of white bread., Food Control, 133, p. 108688, DOI: 10.1016/j.foodcont.2021.108688 10 10.1016/j.foodcont.2021.108688 false true Reference 65711237 /api/reference/65711237 11. Bahmid 2021: Development of a moisture-activated antimicrobial film containing ground mustard seeds and its application on meat in active packaging system., Food Packag. Shelf Life, 30, p. 100753, DOI: 10.1016/j.fpsl.2021.100753 11 10.1016/j.fpsl.2021.100753 false true Reference 65711238 /api/reference/65711238 12. Kara 2016: Antibacterial poly(lactic acid) (PLA) films grafted with electrospun PLA/allyl isothiocyanate fibers for food packaging., J. Appl. Polym. Sci., 133, p. 42475, DOI: 10.1002/app.42475 12 10.1002/app.42475 false true Reference 65711239 /api/reference/65711239 13. Plackett 2007: Behavior of α- and β-cyclodextrin-encapsulated allyl isothiocyanate as slow-release additives in polylactide-co-polycaprolactone films., J. Appl. Polym. Sci., 105, p. 2850, DOI: 10.1002/app.26344 13 10.1002/app.26344 false true Reference 65711240 /api/reference/65711240 14. Dias 2013: Use of allyl isothiocyanate and carbon nanotubes in an antimicrobial film to package shredded, cooked chicken meat., Food Chem., 141, p. 3160, DOI: 10.1016/j.foodchem.2013.05.148 14 10.1016/j.foodchem.2013.05.148 false true Reference 65711241 /api/reference/65711241 15. Tornuk 2022: Development of polycaprolactone biodegradable films reinforced with silver-doped organoclay and effect on the microbiological quality of ground beef meat., J. Food Process Preserv., 46, p. e16862 15 false true Reference 65711242 /api/reference/65711242 16. Mutlu 2023: Physicochemical and antimicrobial properties of biodegradable films based on gelatin/guar gum incorporated with grape seed oil., J. Food Meas. Charact., 17, p. 1515, DOI: 10.1007/s11694-022-01726-2 16 10.1007/s11694-022-01726-2 false true Reference 65711243 /api/reference/65711243 17. Akman, P.K., Kutlu, G., and Tornuk, F. (2023). Development and characterization of a novel sodium alginate based active film supplemented with Lactiplantibacillus plantarum postbiotic. Int. J. Biol. Macromol., 244., DOI: 10.1016/j.ijbiomac.2023.125240 17 10.1016/j.ijbiomac.2023.125240 false true Reference 65711244 /api/reference/65711244 18. Kumari, S.V.G., Pakshirajan, K., and Pugazhenthi, G. (2023). Facile fabrication and characterization of novel antimicrobial and antioxidant poly (3-hydroxybutyrate)/essential oil composites for potential use in active food packaging applications. Int. J. Biol. Macromol., 252., DOI: 10.1016/j.ijbiomac.2023.126566 18 10.1016/j.ijbiomac.2023.126566 false true Reference 65711245 /api/reference/65711245 19. Tornuk 2017: Production and characterization of a new biodegradable fenugreek seed gum based active nanocomposite film reinforced with nanoclays., Int. J. Biol. Macromol., 103, p. 669, DOI: 10.1016/j.ijbiomac.2017.05.090 19 10.1016/j.ijbiomac.2017.05.090 false true Reference 65711246 /api/reference/65711246 20. Kurt 2014: Characterization of a new biodegradable edible film made from salep glucomannan., Carbohydr. Polym., 104, p. 50, DOI: 10.1016/j.carbpol.2014.01.003 20 10.1016/j.carbpol.2014.01.003 false true Reference 65711247 /api/reference/65711247 21. Mahcene 2020: Development and characterization of sodium alginate based active edible films incorporated with essential oils of some medicinal plants., Int. J. Biol. Macromol., 145, p. 124, DOI: 10.1016/j.ijbiomac.2019.12.093 21 10.1016/j.ijbiomac.2019.12.093 false true Reference 65711248 /api/reference/65711248 22. Atlar, G.C., Kutlu, G., and Tornuk, F. (2024). Design and characterization of chitosan-based films incorporated with summer savory (Satureja hortensis L.) essential oil for active packaging. Int. J. Biol. Macromol., 254., DOI: 10.1016/j.ijbiomac.2023.127732 22 10.1016/j.ijbiomac.2023.127732 false true Reference 65711249 /api/reference/65711249 23. Apak 2004: Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method., J. Agric. Food Chem., 52, p. 7970, DOI: 10.1021/jf048741x 23 10.1021/jf048741x false true Reference 65711250 /api/reference/65711250 24. Sharma, S., Barkauskaite, S., Duffy, B., Jaiswal, A.K., and Jaiswal, S. (2020). Characterization and Antimicrobial Activity of Biodegradable Active Packaging Enriched with Clove and Thyme Essential Oil for Food Packaging Application. Foods, 9., DOI: 10.3390/foods9081117 24 10.3390/foods9081117 false true Reference 65711251 /api/reference/65711251 25. Nisar 2018: Characterization of citrus pectin films integrated with clove bud essential oil: Physical, thermal, barrier, antioxidant and antibacterial properties., Int. J. Biol. Macromol., 106, p. 670, DOI: 10.1016/j.ijbiomac.2017.08.068 25 10.1016/j.ijbiomac.2017.08.068 false true Reference 65711252 /api/reference/65711252 26. Rech 2020: Biodegradation of eugenol-loaded polyhydroxybutyrate films in different soil types., Case Stud. Chem. Environ. Eng., 2, p. 100014, DOI: 10.1016/j.cscee.2020.100014 26 10.1016/j.cscee.2020.100014 false true Reference 65711253 /api/reference/65711253 27. Przybysz 2018: Structural, mechanical and thermal behavior assessments of PCL/PHB blends reactively compatibilized with organic peroxides., Polym. Test., 67, p. 513, DOI: 10.1016/j.polymertesting.2018.03.014 27 10.1016/j.polymertesting.2018.03.014 false true Reference 65711254 /api/reference/65711254 28. Engler, L.G., Della Giustina, M., Giovanela, M., Roesch-Ely, M., Gately, N., Major, I., Crespo, J.S., and Devine, D.M. (2025). Exploring the Synergy of Metallic Antimicrobial Agents in Ternary Blends of PHB/PLA/PCL. J. Biomed. Mater. Res. A, 113., DOI: 10.1002/jbm.a.37857 28 10.1002/jbm.a.37857 false true Reference 65711255 /api/reference/65711255 29. Erceg, T., Rackov, S., Terek, P., and Pilić, B. (2023). Preparation and Characterization of PHBV/PCL-Diol Blend Films. Polymers, 15., DOI: 10.3390/polym15244694 29 10.3390/polym15244694 false true Reference 65711256 /api/reference/65711256 30. Manikandan, N.A., Pakshirajan, K., and Pugazhenthi, G. (2020). A closed-loop biorefinery approach for polyhydroxybutyrate (PHB) production using sugars from carob pods as the sole raw material and downstream processing using the co-product lignin. Bioresour. Technol., 307., DOI: 10.1016/j.biortech.2020.123247 30 10.1016/j.biortech.2020.123247 false true Reference 65711257 /api/reference/65711257 31. Melendez-Rodriguez, B., Torres-Giner, S., Angulo, I., Pardo-Figuerez, M., Hilliou, L., Escuin, J.M., Cabedo, L., Nevo, Y., Prieto, C., and Lagaron, J.M. (2021). High-Oxygen-Barrier Multilayer Films Based on Polyhydroxyalkanoates and Cellulose Nanocrystals. Nanomaterials, 11., DOI: 10.3390/nano11061443 31 10.3390/nano11061443 false true Reference 65711258 /api/reference/65711258 32. Arrieta 2014: Ternary PLA–PHB–Limonene blends intended for biodegradable food packaging applications., Eur. Polym. J., 50, p. 255, DOI: 10.1016/j.eurpolymj.2013.11.009 32 10.1016/j.eurpolymj.2013.11.009 false true Reference 65711259 /api/reference/65711259 33. Othman 2022: Biodegradable dual-layer Polyhydroxyalkanoate (pha)/Polycaprolactone (pcl) mulch film for agriculture: Preparation and characterization., Energy Nexus, 8, p. 100137, DOI: 10.1016/j.nexus.2022.100137 33 10.1016/j.nexus.2022.100137 false true Reference 65711260 /api/reference/65711260 34. Rech 2021: Antimicrobial and Physical–Mechanical Properties of Polyhydroxybutyrate Edible Films Containing Essential Oil Mixtures., J. Polym. Environ., 29, p. 1202, DOI: 10.1007/s10924-020-01943-0 34 10.1007/s10924-020-01943-0 false true Reference 65711261 /api/reference/65711261 35. Joszko 2024: Comprehensive study of antimicrobial polycaprolactone/clay nanocomposite films: Preparation, characterization, properties and degradation in simulated body fluid., Polym. Compos., 45, p. 9280, DOI: 10.1002/pc.28409 35 10.1002/pc.28409 false true Reference 65711262 /api/reference/65711262 36. Altaee 2016: Biodegradation of different formulations of polyhydroxybutyrate films in soil., SpringerPlus, 5, p. 762, DOI: 10.1186/s40064-016-2480-2 36 10.1186/s40064-016-2480-2 false true Reference 65711263 /api/reference/65711263 37. Immirzi 2003: Biodegradation of poly-ε-caprolactone/poly-β-hydroxybutyrate blend., Polym. Degrad. Stab., 79, p. 37, DOI: 10.1016/S0141-3910(02)00236-7 37 10.1016/S0141-3910(02)00236-7 false true Reference 65711264 /api/reference/65711264 38. Sousa 2022: Effect of composition on permeability, mechanical properties and biodegradation of PBAT/PCL blends films., Polym. Bull., 79, p. 5327, DOI: 10.1007/s00289-021-03745-3 38 10.1007/s00289-021-03745-3 false true Reference 65711265 /api/reference/65711265 39. Giaquinto 2017: Evaluation of the mechanical and thermal properties of PHB/canola oil films., Polímeros, 27, p. 201, DOI: 10.1590/0104-1428.10716 39 10.1590/0104-1428.10716 false true Reference 65711266 /api/reference/65711266 40. Fuster 2013: Antibacterial performance of solvent cast polycaprolactone (PCL) films containing essential oils., Food Control, 34, p. 214, DOI: 10.1016/j.foodcont.2013.04.025 40 10.1016/j.foodcont.2013.04.025 false true Reference 65711267 /api/reference/65711267 41. Wang 2010: Effect of allyl isothiocyanate on antioxidants and fruit decay of blueberries., Food Chem., 120, p. 199, DOI: 10.1016/j.foodchem.2009.10.007 41 10.1016/j.foodchem.2009.10.007 false true Reference 65711268 /api/reference/65711268 42. Lin 2000: Antibacterial Mechanism of Allyl Isothiocyanate †., J. Food Prot., 63, p. 727, DOI: 10.4315/0362-028X-63.6.727 42 10.4315/0362-028X-63.6.727 false true Reference 65711269 /api/reference/65711269 43. Alibrahem, W., Nguyen, D.H.H., Helu, N.K., Tóth, F., Nagy, P.T., Posta, J., Prokisch, J., and Oláh, C. (2025). Health Benefits, Applications, and Analytical Methods of Freshly Produced Allyl Isothiocyanate. Foods, 14., DOI: 10.3390/foods14040579 43 10.3390/foods14040579 false true Reference 65711270 /api/reference/65711270 44. Rajakumar 2024: Allyl isothiocyanate regulates oxidative stress, inflammation, cell proliferation, cell cycle arrest, apoptosis, angiogenesis, invasion and metastasis via interaction with multiple cell signaling pathways., Histochem. Cell Biol., 161, p. 211, DOI: 10.1007/s00418-023-02255-9 44 10.1007/s00418-023-02255-9 false true /api/publication/36126854 Memis Karabuga Saliha et al. Fabrication and Characterization of Poly(hydroxybutyrate)- and Poly(caprolactone)-Based Active Biodegradable Films Incorporating Allyl Isothiocyanate. (2025) POLYMERS 2073-4360 17 9 p. 1189<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Memis Karabuga Saliha </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Akman Perihan Kubra </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Tornuk Fatih </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36126854" target="_blank">Fabrication and Characterization of Poly(hydroxybutyrate)- and Poly(caprolactone)-Based Active Biodegradable Films Incorporating Allyl Isothiocyanate</a></div> <div> <span class="journal-title">POLYMERS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2073-4360">2073-4360</a>)</span>: <span class="journal-volume">17</span> <span class="journal-issue">9</span> <span class="page"> p. 1189. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3390/polym17091189" target="_blank" href="https://doi.org/10.3390/polym17091189"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001486140400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001486140400001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="https://www.mdpi.com/2073-4360/17/9/1189" target="_blank" href="https://www.mdpi.com/2073-4360/17/9/1189"> Egyéb URL </a> </span> </span> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36126854&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36126854</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2025.12.22. 11:00 Szuper Admin (admin) </div> </div></div>