Unlocking the power of immune checkpoint inhibitors: Targeting YAP1 reduces anti‐PD1 resistance in skin cutaneous melanoma

Kovács, Szonja Anna [Kovács, Szonja Anna (Molekuláris biológia), author] Bioinformatika Tanszék (SU / FM / I); Kovács, Tamás [Kovács, Tamás (Molekuláris orvos...), author] Department of Pharmacology and Pharmacotherapy (SU / FM / I); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); MTA-SE Momentum Cardio-Oncology and Cardioimmun... (SU / FM / I / DPP); Lánczky, András; Paál, Ágnes [Paál, Ágnes (farmakológia), author] Department of Pharmacology and Pharmacotherapy (SU / FM / I); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); MTA-SE Momentum Cardio-Oncology and Cardioimmun... (SU / FM / I / DPP); Hegedűs, Zsombor I. [Hegedűs, Zsombor (molekuláris biológia), author] Department of Pharmacology and Pharmacotherapy (SU / FM / I); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); MTA-SE Momentum Cardio-Oncology and Cardioimmun... (SU / FM / I / DPP); Sayour, Nabil V. [Sayour, Viktor Nabil (farmakológia), author] Department of Pharmacology and Pharmacotherapy (SU / FM / I); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); MTA-SE Momentum Cardio-Oncology and Cardioimmun... (SU / FM / I / DPP); Szabó, Lilla [Szabó, Lilla (Farmakológia), author] Department of Pharmacology and Pharmacotherapy (SU / FM / I); HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); MTA-SE Momentum Cardio-Oncology and Cardioimmun... (SU / FM / I / DPP); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); Kovács, Andrea [Kovács, Andrea (hisztológia, immu...), author] Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); Department of Pharmacology and Pharmacotherapy (SU / FM / I); MTA-SE Momentum Cardio-Oncology and Cardioimmun... (SU / FM / I / DPP); HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); Bianchini, Giampaolo; Ferdinandy, Péter [Ferdinandy, Péter (Farmakológia, mol...), author] Department of Pharmacology and Pharmacotherapy (SU / FM / I); Ocana, Alberto; Varga, Zoltán V. [Varga, Zoltán (kardiovaszkuláris...), author] Department of Pharmacology and Pharmacotherapy (SU / FM / I); Centre for Pharmacology and Pharmaceutical Rese... (SU / KSZE); HCEMM-SU Cardiometabolic Immunology Research Group (SU / FM / I / DPP); MTA-SE Momentum Cardio-Oncology and Cardioimmun... (SU / FM / I / DPP); Fekete, János Tibor [Fekete, János Tibor (Prediktív biomark...), author] Bioinformatika Tanszék (SU / FM / I); Enzim_417 (IMLS); Győrffy, Balázs ✉ [Győrffy, Balázs (Onkológia), author] Bioinformatika Tanszék (SU / FM / I); Department of Biophysics (UP / UPMS)

Fundings:

• (2022-1.1.1-KK-2022-00005)
• (KDP-14-3/PALY-2021)
• Nemzeti Gyógyszerkutatási és Fejlesztési Laboratórium (PharmaLab)(RRF-2.3.1-21-2022-00015) Funder: NRDIO
• (ÚNKP-23-4-I-SE-5)
• (RRF-2.3.1-2022-00003)
• HCEMM(739593) Funder: Horizon 2020
• (LP-2021-14)