https://m2.mtmt.hu/ hun 2026-09-22 07:51 JournalArticle 36116891 VALIDATED true Funding Agency and Grant Number: European Union; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences; [RRF-2.3.1-21-2022-00003] Funding text: Project no. RRF-2.3.1-21-2022-00003 has been implemented with the support provided by the European Union. A.K. was supported by the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences. 0 false 2026-07-08T08:37:21.944+0000 2026-07-06T06:52:53.149+0000 2025-05-02T15:20:42.702+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin Molnár-Taga Márta (SE 4-es admin) true 10062250 2026-07-06T06:53:28.843+0000 2026-06-08T10:54:02.884+0000 true 10062062 Gere Tamásné /api/admin/10062062 Admin Gere Tamásné (SE_KK_Admin5_GT, admin) true 10062062 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Teszák, Tímea true true /api/journal/10056704 REVIEWED BIOMEDICINES 2227-9059 true false 10056704 false 10056704 true 2227-9059 Journal FOREIGN 13 4 841 841 12 2025 Background/Objectives: Donor-derived cell-free DNA (dd-cfDNA) is a marker of graft injury that increases in acute rejection and has excellent negative predictive value. Left ventricular global longitudinal strain (LVGLS) and strain-derived myocardial work indices are novel echocardiographic parameters with growing applications. Still, they have been poorly investigated in heart transplant (HTx) recipients so far. We sought to examine the diagnostic impact of left ventricular longitudinal strain-derived indices in diagnosing myocardial injury as assessed by dd-cfDNA after HTx. Methods: Since October 2022, HTx recipients have been shifted from our endomyocardial biopsy (EMB)-based rejection surveillance protocol to a monthly dd-cfDNA-led rejection assessment. We analysed the percentage of donor-derived to total cell-free DNA. For echocardiographic analysis, patient selection was restricted to those transplanted ≥ 6 months. We used 2D speckle-tracking echocardiography to assess LVGLS and strain-derived myocardial work parameters. Results: We analysed four hundred and forty-nine dd-cfDNA samples from seventy-one patients until November 2024. The mean dd-cfDNA fraction remained very low (0.13 ± 0.06%). Eighty-eight percent of surveillance EMBs that would have otherwise been performed were avoided. The mean LVGLS was lower than the literature reference values. We found no correlation between dd-cfDNA and LVGLS. Transplanted hearts had different myocardial work indices than the reference values reported in the literature. Conclusions: dd-cfDNA effectively rules out clinically significant acute rejection and decreases the need for invasive surveillance EMBs. LVGLS seems less sensitive than dd-cfDNA for the identification of myocardial injury in the early stages of HTx rejection in patients at low risk for rejection. Funding 2052428 /api/funding/2052428 Nemzeti Kardiovaszkuláris Laboratórium(RRF-2.3.1-21-2022-00003) Támogató: NKFIH false true Funding 2052429 /api/funding/2052429 János Bolyai Research Scholarship of the Hungarian Academy of Sciences false true true 2025 true true true false true false GOLD 2026-07-08 true https://doi.org/10.3390/biomedicines13040841 1 0 1 1 0 1 1 1 1 1 1 1 1 1 0 0 1 1 1 1 0 1 1 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2026 0 1 1 1 1 Q1 false 10026799 false false false 2025-05-01T15:20:50.424+0000 Kardiológia Központ - Kardiológiai Tanszék (SE / AOK / K); Kísérletes Kardiológiai és Sebészeti Műtéttani ... (SE / AOK / K); Patológiai és Kísérleti Rákkutató Intézet (SE / AOK / I); Repülõ- és Űrorvostani Tanszék (SE / AOK / K); Sportorvostan Tanszék (SE / AOK / K); Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K) 9 45 6 11 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 126306710 /api/authorship/126306710 Teszák, Tímea ✉ [Teszák, Tímea (Kardiológia), szerző] Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K) 1 0.091 true false true Author 10089116 /api/author/10089116 Teszák Tímea (Kardiológia) Teszák Tímea true true Teszák Tímea true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306711 /api/authorship/126306711 Barcziova, Timea 2 0.09090909 false false false Barcziova Timea true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306712 /api/authorship/126306712 Bödör, Csaba [Bödör, Csaba (Molekuláris Onkoh...), szerző] Patológiai és Kísérleti Rákkutató Intézet (SE / AOK / I) 3 0.091 false false false Author 10025100 /api/author/10025100 Bödör Csaba (Molekuláris Onkohematológia) Bödör Csaba true 10025100 true Bödör Csaba true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306713 /api/authorship/126306713 Hegyi, Lajos [Hegyi, Lajos (Molekuláris biológia), szerző] Patológiai és Kísérleti Rákkutató Intézet (SE / AOK / I) 4 0.091 false false false Author 10092627 /api/author/10092627 Hegyi Lajos (Molekuláris biológia) Hegyi Lajos true true Hegyi Lajos true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306714 /api/authorship/126306714 Lévay, Luca 5 0.091 false false false Lévay Luca true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306715 /api/authorship/126306715 Nagy, Beáta [Nagy, Beáta (Patológia), szerző] Patológiai és Kísérleti Rákkutató Intézet (SE / AOK / I) 6 0.091 false false false Author 10052106 /api/author/10052106 Nagy Beáta (Patológia) Nagy Beáta true 10052106 true Nagy Beáta true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306716 /api/authorship/126306716 Fintha, Attila [Fintha, Attila (patológia), szerző] Patológiai és Kísérleti Rákkutató Intézet (SE / AOK / I) 7 0.091 false false false Author 10026799 /api/author/10026799 Fintha Attila (patológia) Fintha Attila true 10026799 true Fintha Attila true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306717 /api/authorship/126306717 Szijártó, Ádám [Szijártó, Ádám (informatika, mest...), szerző] Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K) 8 0.091 false false false Author 10079466 /api/author/10079466 Szijártó Ádám (informatika, mesterséges intelligencia) Szijártó Ádám true true Szijártó Ádám true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306718 /api/authorship/126306718 Kovács, Attila [Kovács, Attila (kardiológia, spor...), szerző] Kardiológia Központ - Kardiológiai Tanszék (SE / AOK / K); Kísérletes Kardiológiai és Sebészeti Műtéttani ... (SE / AOK / K) 9 0.091 false false false Author 10035614 /api/author/10035614 Kovács Attila (kardiológia, sportkardiológia) Kovács Attila true 10035614 true Kovács Attila true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306719 /api/authorship/126306719 Merkely, Béla [Merkely, Béla Péter (Kardiológia), szerző] Kardiológia Központ - Kardiológiai Tanszék (SE / AOK / K); Repülõ- és Űrorvostani Tanszék (SE / AOK / K); Sportorvostan Tanszék (SE / AOK / K) 10 0.091 false false false Author 10002691 /api/author/10002691 Merkely Béla Péter (Kardiológia) Merkely Béla Péter true 10002691 true Merkely Béla true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126306720 /api/authorship/126306720 Sax, Balazs [Sax, Balázs (Orvostudományok), szerző] Kardiológia Központ - Kardiológiai Tanszék (SE / AOK / K) 11 0.091 false true false Author 10022860 /api/author/10022860 Sax Balázs (Orvostudományok) Sax Balázs true 10022860 true Sax Balazs true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 29300329 /api/publicationidentifier/29300329 DOI: 10.3390/biomedicines13040841 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/biomedicines13040841 https://doi.org/10.3390/biomedicines13040841 false true PublicationIdentifier 29353657 /api/publicationidentifier/29353657 WoS: 001477280200001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001477280200001 https://www.webofscience.com/wos/woscc/full-record/001477280200001 true true PublicationIdentifier 29353658 /api/publicationidentifier/29353658 Scopus: 105003691468 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105003691468 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105003691468 true true PublicationIdentifier 29305112 /api/publicationidentifier/29305112 PubMed: 40299413 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40299413 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40299413&dopt=Abstract true true SjrRating 11560372 /api/sjrrating/11560372 sjr:Q1 (2025) Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous) BIOMEDICINES 2227-9059 74 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1301 /api/classificationexternal/1301 Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous) true 1301 true Q1 DIRECT true true Reference 65600794 /api/reference/65600794 1. Velleca 2023: The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients., J. Heart Lung Transplant., 42, p. e1, DOI: 10.1016/j.healun.2022.10.015 1 10.1016/j.healun.2022.10.015 false true Reference 65600795 /api/reference/65600795 2. Cusi 2024: Incidence of Acute Rejection Compared With Endomyocardial Biopsy Complications for Heart Transplant Patients in the Contemporary Era., Transplantation, 108, p. 1220 2 false true Reference 65600796 /api/reference/65600796 3. Khush 2019: Noninvasive detection of graft injury after heart transplant using donor-derived cell-free DNA: A prospective multicenter study., Am. J. Transplant., 19, p. 2889, DOI: 10.1111/ajt.15339 3 10.1111/ajt.15339 false true Reference 65600797 /api/reference/65600797 4. Oh 2021: Protocol endomyocardial biopsy beyond 6 months-It is time to move on., Am. J. Transplant., 21, p. 825, DOI: 10.1111/ajt.16128 4 10.1111/ajt.16128 false true Reference 65600798 /api/reference/65600798 5. Isath, A., and Mehra, M.R. (2024). “Surveillance Without Scars”: The Quest for Non-Invasive Detection of Cardiac Allograft Rejection. J. Heart Lung Transplant., in press., DOI: 10.1016/j.healun.2024.12.005 5 10.1016/j.healun.2024.12.005 false true Reference 65600799 /api/reference/65600799 6. Shah 2021: Cell-Free DNA to Detect Heart Allograft Acute Rejection., Circulation, 143, p. 1184, DOI: 10.1161/CIRCULATIONAHA.120.049098 6 10.1161/CIRCULATIONAHA.120.049098 false true Reference 65600800 /api/reference/65600800 7. Kim 2022: A novel donor-derived cell-free DNA assay for the detection of acute rejection in heart transplantation., J. Heart Lung Transplant., 41, p. 919, DOI: 10.1016/j.healun.2022.04.002 7 10.1016/j.healun.2022.04.002 false true Reference 65600801 /api/reference/65600801 8. Teszak 2023: Local laboratory-run donor-derived cell-free DNA assay for rejection surveillance in heart transplantation-first six months of clinical experience., Clin. Transplant., 37, p. e15078, DOI: 10.1111/ctr.15078 8 10.1111/ctr.15078 false true Reference 65600802 /api/reference/65600802 9. Nikolova 2024: European Society for Organ Transplantation (ESOT) Consensus Statement on the Use of Non-invasive Biomarkers for Cardiothoracic Transplant Rejection Surveillance., Transpl. Int., 37, p. 12445, DOI: 10.3389/ti.2024.12445 9 10.3389/ti.2024.12445 false true Reference 65600803 /api/reference/65600803 10. Kobashigawa 2023: The evolving use of biomarkers in heart transplantation: Consensus of an expert panel., Am. J. Transplant., 23, p. 727, DOI: 10.1016/j.ajt.2023.02.025 10 10.1016/j.ajt.2023.02.025 false true Reference 65600804 /api/reference/65600804 11. Jimenez-Blanco, M., Crespo-Leiro, M.G., Garcia-Cosio Carmena, M.D., Gomez Bueno, M., Lopez-Vilella, R., Ortiz-Bautista, C., Farrero-Torres, M., Zegri-Reiriz, I., Diaz-Molina, B., and Garcia-Romero, E. (2024). Donor-derived cell-free DNA as a new biomarker for cardiac allograft rejection: A prospective study (FreeDNA-CAR). J. Heart Lung Transplant., in press., DOI: 10.1016/j.healun.2024.11.009 11 10.1016/j.healun.2024.11.009 false true Reference 65600805 /api/reference/65600805 12. Cruz 2021: Usefulness of speckle tracking echocardiography and biomarkers for detecting acute cellular rejection after heart transplantation., Cardiovasc. Ultrasound, 19, p. 6, DOI: 10.1186/s12947-020-00235-w 12 10.1186/s12947-020-00235-w false true Reference 65600806 /api/reference/65600806 13. Chamberlain 2022: Prognostic Value of Left and right ventricular deformation strain analysis on Acute Cellular rejection in Heart Transplant recipients: A 6-year outcome study., Int. J. Cardiovasc. Imaging, 38, p. 2271, DOI: 10.1007/s10554-022-02586-z 13 10.1007/s10554-022-02586-z false true Reference 65600807 /api/reference/65600807 14. Eleid 2010: Natural history of left ventricular mechanics in transplanted hearts: Relationships with clinical variables and genetic expression profiles of allograft rejection., JACC Cardiovasc. Imaging, 3, p. 989, DOI: 10.1016/j.jcmg.2010.07.009 14 10.1016/j.jcmg.2010.07.009 false true Reference 65600808 /api/reference/65600808 15. Syeda 2011: Two-dimensional speckle-tracking strain echocardiography in long-term heart transplant patients: A study comparing deformation parameters and ejection fraction derived from echocardiography and multislice computed tomography., Eur. J. Echocardiogr., 12, p. 490, DOI: 10.1093/ejechocard/jer064 15 10.1093/ejechocard/jer064 false true Reference 65600809 /api/reference/65600809 16. Lang 2015: Recommendations for cardiac chamber quantification by echocardiography in adults: An update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging., Eur. Heart J. Cardiovasc. Imaging, 16, p. 233, DOI: 10.1093/ehjci/jev014 16 10.1093/ehjci/jev014 false true Reference 65600810 /api/reference/65600810 17. Badano 2015: European Association of Cardiovascular Imaging/Cardiovascular Imaging Department of the Brazilian Society of Cardiology recommendations for the use of cardiac imaging to assess and follow patients after heart transplantation., Eur. Heart J. Cardiovasc. Imaging, 16, p. 919, DOI: 10.1093/ehjci/jev139 17 10.1093/ehjci/jev139 false true Reference 65600811 /api/reference/65600811 18. Kyrouac 2022: Echocardiographic and clinical predictors of cardiac amyloidosis: Limitations of apical sparing., ESC Heart Fail, 9, p. 385, DOI: 10.1002/ehf2.13738 18 10.1002/ehf2.13738 false true Reference 65600812 /api/reference/65600812 19. Fisicaro 2024: Timing and Patient Position During Cuff Blood Pressure Measurement Affect Myocardial Work Parameters Measured by Echocardiography., J. Am. Soc. Echocardiogr., 37, p. 690, DOI: 10.1016/j.echo.2024.03.018 19 10.1016/j.echo.2024.03.018 false true Reference 65600813 /api/reference/65600813 20. Moya 2023: State-of-the-Art: Noninvasive Assessment of Left Ventricular Function Through Myocardial Work., J. Am. Soc. Echocardiogr., 36, p. 1027, DOI: 10.1016/j.echo.2023.07.002 20 10.1016/j.echo.2023.07.002 false true Reference 65600814 /api/reference/65600814 21. Marzlin 2023: Myocardial Work in Echocardiography., Circ. Cardiovasc. Imaging, 16, p. e014419, DOI: 10.1161/CIRCIMAGING.122.014419 21 10.1161/CIRCIMAGING.122.014419 false true Reference 65600815 /api/reference/65600815 22. Casas 2024: Multi-centre analytical performance verification of an IVD assay to quantify donor-derived cell-free DNA in solid organ transplant recipients., HLA, 103, p. e15518, DOI: 10.1111/tan.15518 22 10.1111/tan.15518 false true Reference 65600816 /api/reference/65600816 23. Grskovic 2016: Validation of a Clinical-Grade Assay to Measure Donor-Derived Cell-Free DNA in Solid Organ Transplant Recipients., J. Mol. Diagn., 18, p. 890, DOI: 10.1016/j.jmoldx.2016.07.003 23 10.1016/j.jmoldx.2016.07.003 false true Reference 65600817 /api/reference/65600817 24. Berry 2013: The 2013 International Society for Heart and Lung Transplantation Working Formulation for the standardization of nomenclature in the pathologic diagnosis of antibody-mediated rejection in heart transplantation., J. Heart Lung Transplant., 32, p. 1147, DOI: 10.1016/j.healun.2013.08.011 24 10.1016/j.healun.2013.08.011 false true Reference 65600818 /api/reference/65600818 25. Sugimoto 2017: Echocardiographic reference ranges for normal left ventricular 2D strain: Results from the EACVI NORRE study., Eur. Heart J. Cardiovasc. Imaging, 18, p. 833, DOI: 10.1093/ehjci/jex140 25 10.1093/ehjci/jex140 false true Reference 65600819 /api/reference/65600819 26. Manganaro 2019: Echocardiographic reference ranges for normal non-invasive myocardial work indices: Results from the EACVI NORRE study., Eur. Heart J. Cardiovasc. Imaging, 20, p. 582, DOI: 10.1093/ehjci/jey188 26 10.1093/ehjci/jey188 false true Reference 65600820 /api/reference/65600820 27. Rodriguez-Diego, S., Ruiz-Ortiz, M., Delgado-Ortega, M., Kim, J., Weinsaft, J.W., Sanchez-Fernandez, J.J., Ortega-Salas, R., Carnero-Montoro, L., Carrasco-Avalos, F., and Lopez-Aguilera, J. (2022). The Role of Left Atrial Longitudinal Strain in the Diagnosis of Acute Cellular Rejection in Heart Transplant Recipients. J. Clin. Med., 11., DOI: 10.3390/jcm11174987 27 10.3390/jcm11174987 false true Reference 65600821 /api/reference/65600821 28. Ciarka 2022: Speckle-tracking-based global longitudinal and circumferential strain detect early signs of antibody-mediated rejection in heart transplant patients., Eur. Heart J. Cardiovasc. Imaging, 23, p. 1520, DOI: 10.1093/ehjci/jeab212 28 10.1093/ehjci/jeab212 false true Reference 65600822 /api/reference/65600822 29. Barakat 2017: Prognostic Utility of Right Ventricular Free Wall Strain in Low Risk Patients After Orthotopic Heart Transplantation., Am. J. Cardiol., 119, p. 1890, DOI: 10.1016/j.amjcard.2017.03.003 29 10.1016/j.amjcard.2017.03.003 false true Reference 65600823 /api/reference/65600823 30. Otto, M.E.B., Martins, A.M.A., Campos Dall’Orto, A.O.M., Leite, S.F., de Queiroz Mauricio Filho, M.A.F., Martins, N.T., de Araujo, S.R., Almeida, S.V., Paiva, M.U.B., and Atik, F.A. (2022). Acute Cellular Rejection in Heart Transplant Patients: Insights of Global Longitudinal Strain, Myocardial Work, and an Exclusive Group of Chagas Disease. Front. Cardiovasc. Med., 9., DOI: 10.3389/fcvm.2022.841698 30 10.3389/fcvm.2022.841698 false true Reference 65600824 /api/reference/65600824 31. Leitman, M., and Tyomkin, V. (2024). Apical Sparing in Routine Echocardiography: Occurrence and Clinical Significance. J. Cardiovasc. Dev. Dis., 11., DOI: 10.3390/jcdd11090262 31 10.3390/jcdd11090262 false true Reference 65600825 /api/reference/65600825 32. Mandoli 2024: Reference Values of Strain-derived Myocardial Work Indices in Heart Transplant Patients., Eur. Heart J. Imaging Methods Pract., 2, p. qyae091, DOI: 10.1093/ehjimp/qyae091 32 10.1093/ehjimp/qyae091 false true Reference 65600826 /api/reference/65600826 33. Valantine 2014: Circulating cell-free DNA enables noninvasive diagnosis of heart transplant rejection., Sci. Transl. Med., 6, p. ra277 33 false true Reference 65600827 /api/reference/65600827 34. Kostyukevich 2019: A Roadmap to Assess Myocardial Work: From Theory to Clinical Practice., JACC Cardiovasc. Imaging, 12, p. 2549, DOI: 10.1016/j.jcmg.2019.05.028 34 10.1016/j.jcmg.2019.05.028 false true Reference 65600828 /api/reference/65600828 35. Pradhan 2022: Decreased Global Myocardial Work Efficiency Correlates with Coronary Vasculopathy in Pediatric Heart Transplant Patients., Pediatr. Cardiol., 43, p. 515, DOI: 10.1007/s00246-021-02748-1 35 10.1007/s00246-021-02748-1 false true Reference 65600829 /api/reference/65600829 36. Sade 2023: Approach to optimal assessment of right ventricular remodelling in heart transplant recipients: Insights from myocardial work index, T1 mapping, and endomyocardial biopsy., Eur. Heart J. Cardiovasc. Imaging, 24, p. 354, DOI: 10.1093/ehjci/jeac108 36 10.1093/ehjci/jeac108 false true /api/publication/36116891 Teszák Tímea et al. Donor-Derived Cell-Free DNA Versus Left Ventricular Longitudinal Strain and Strain-Derived Myocardial Work Indices for Identification of Heart Transplant Injury. (2025) BIOMEDICINES 2227-9059 13 4<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10089116"><a href="/gui2/?type=authors&mode=browse&sel=10089116" target="_blank">Teszák Tímea ✉ (<span class="authorship-author-name">Teszák Tímea</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Barcziova Timea </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10025100"><a href="/gui2/?type=authors&mode=browse&sel=10025100" target="_blank">Bödör Csaba (<span class="authorship-author-name">Bödör Csaba</span> <span class="authorAux-mtmt"> Molekuláris Onkohematológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Patológiai és Kísérleti Rákkutató Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10092627"><a href="/gui2/?type=authors&mode=browse&sel=10092627" target="_blank">Hegyi Lajos (<span class="authorship-author-name">Hegyi Lajos</span> <span class="authorAux-mtmt"> Molekuláris biológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Patológiai és Kísérleti Rákkutató Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Lévay Luca </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10052106"><a href="/gui2/?type=authors&mode=browse&sel=10052106" target="_blank">Nagy Beáta (<span class="authorship-author-name">Nagy Beáta</span> <span class="authorAux-mtmt"> Patológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Patológiai és Kísérleti Rákkutató Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10026799"><a href="/gui2/?type=authors&mode=browse&sel=10026799" target="_blank">Fintha Attila (<span class="authorship-author-name">Fintha Attila</span> <span class="authorAux-mtmt"> patológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Patológiai és Kísérleti Rákkutató Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10079466"><a href="/gui2/?type=authors&mode=browse&sel=10079466" target="_blank">Szijártó Ádám (<span class="authorship-author-name">Szijártó Ádám</span> <span class="authorAux-mtmt"> informatika, mesterséges intelligencia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10035614"><a href="/gui2/?type=authors&mode=browse&sel=10035614" target="_blank">Kovács Attila (<span class="authorship-author-name">Kovács Attila</span> <span class="authorAux-mtmt"> kardiológia, sportkardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kísérletes Kardiológiai és Sebészeti Műtéttani Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002691"><a href="/gui2/?type=authors&mode=browse&sel=10002691" target="_blank">Merkely Béla (<span class="authorship-author-name">Merkely Béla Péter</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Repülõ- és Űrorvostani Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Sportorvostan Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10022860"><a href="/gui2/?type=authors&mode=browse&sel=10022860" target="_blank">Sax Balazs (<span class="authorship-author-name">Sax Balázs</span> <span class="authorAux-mtmt"> Orvostudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36116891" target="_blank">Donor-Derived Cell-Free DNA Versus Left Ventricular Longitudinal Strain and Strain-Derived Myocardial Work Indices for Identification of Heart Transplant Injury</a></div> <div> <span class="journal-title">BIOMEDICINES</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2227-9059">2227-9059</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">4</span> <span class="page"> Paper 841. 12 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/biomedicines13040841" target="_blank" href="https://doi.org/10.3390/biomedicines13040841"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001477280200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001477280200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105003691468" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105003691468"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40299413" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40299413&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | Scopus jelölt:&nbsp;1 | WoS/Scopus jelölt:&nbsp;1 | DOI jelölt:&nbsp;1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36116891&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36116891</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> Nemzeti Kardiovaszkuláris Laboratórium(RRF-2.3.1-21-2022-00003) Támogató: NKFIH, János Bolyai Research Scholarship of the Hungarian Academy of Sciences </div> <div class="lastModified">Utolsó módosítás: 2026.07.06. 08:52 Kondor Zóra (SE_KK_Admin5_KZ, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: European Union; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences; [RRF-2.3.1-21-2022-00003] Funding text: Project no. RRF-2.3.1-21-2022-00003 has been implemented with the support provided by the European Union. A.K. was supported by the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences.</pre> </div></div>