https://m2.mtmt.hu/ hun 2026-10-25 15:53 JournalArticle 36100212 VALIDATED true 0 false 2026-10-20T11:56:41.554+0000 2026-09-09T08:29:01.095+0000 2025-04-22T08:31:41.138+0000 true 10081340 Pirmann Tamás /api/admin/10081340 Admin true 2026-01-08T11:22:59.265+0000 2026-01-08T11:22:59.265+0000 2025-10-27T07:54:15.369+0000 true 10101957 Pirmann Tamás /api/admin/10101957 Admin true 2026-09-09T08:29:01.102+0000 true 10082922 Csajbók Edit /api/admin/10082922 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Varga, Levente Reduction of the planning target volume with daily online adaptive radiotherapy in bladder cancer. true true /api/journal/31780 REVIEWED true false 31780 false 31780 true 0179-7158 1439-099X Journal FOREIGN 201 11 1162 1169 1162 8 2025 External radiation therapy for bladder cancer requires large planning target volumes (PTVs) due to the daily anatomy of the bladder. Online adaptive radiotherapy (oART) can reduce the PTV by considering daily anatomical changes.We performed oART in 8 patients with muscle-invasive bladder cancer between June 10, 2022, and April 14, 2023, on an Ethos linear accelerator (Varian, Palo Alto, USA). Using the 496 cone-beam computed tomography (CBCT) images of the fractions, we retrospectively compared the differences in volumetric changes between oART and image-guided and intensity-modulated radiotherapy (IGRT/IMRT). According to our local protocol, for oART, a patient-specific PTV margin was created based on the intrafractional clinical target volume (CTV) changes observed during the first three fractions.The average duration of treatment was 14.8 min (range 7-49 min). The average volume of the PTV with oART and IGRT/IMRT was 296.8 cm3 (range 114.5-810.4 cm3) and 416.5 cm3 (range 188.2-991.3 cm3), respectively, representing a 30% reduction with oART. This new technique resulted in an average reduction of 43.9% in the volume of unnecessarily irradiated healthy tissues. Geometrical miss of the CTV occurred in 13 fractions with IGRT/IMRT, with an average of 9.4 cm3 of missed volume (range 0.4-56.4 cm3, standard deviation [SD] 15.73), for oART in 7 fractions, with an average missed volume of 4 cm3 (range 0.4-21.2 cm3, SD: 7.6).The use of patient-specific margins in oART allows for reduction of the PTV and dose to healthy tissues while achieving equal or better target coverage. Funding 2052124 /api/funding/2052124 false true Funding 2052125 /api/funding/2052125 false true true INTERNATIONAL 2025 true true true false true false NONE 2026-10-20 false 5 0 5 5 0 4 5 4 5 5 5 5 5 5 0 0 5 5 5 5 0 0 0 Folyóiratcikk Journal Article 24 4 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 1 1 1 2026 0 4 4 4 4 Q2 false false false false 2025-07-21T08:31:44.765+0000 Doktori Iskola (SE); Nukleáris Technika Tanszék (BME / TTK / NTI); Onkológiai Tanszék (SE / AOK / K); Országos Onkológiai Intézet 11 20 4 13 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 126221495 /api/authorship/126221495 1 0.07692308 true false false Varga Levente true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221496 /api/authorship/126221496 2 0.077 false false false Author 10083670 /api/author/10083670 Gáldi Ádám true true Gáldi Ádám true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221497 /api/authorship/126221497 3 0.077 false false false Author 10075032 /api/author/10075032 Szegedi Domonkos true true Szegedi Domonkos true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221498 /api/authorship/126221498 4 0.077 false false false Author 10042833 /api/author/10042833 Herein András true 10042833 true Herein András true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221499 /api/authorship/126221499 5 0.07692308 false false false Pulugor Dóra true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221500 /api/authorship/126221500 6 0.077 false false false Author 10085931 /api/author/10085931 Nahaji István true true Nahaji István true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221501 /api/authorship/126221501 7 0.077 false false false Author 10058289 /api/author/10058289 Gesztesi László true 10058289 true Gesztesi László true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221502 /api/authorship/126221502 8 0.077 false false false Author 10064469 /api/author/10064469 Jorgo Kliton true 10064469 true Jorgo Kliton true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221503 /api/authorship/126221503 9 0.077 false false false Author 10013883 /api/author/10013883 Takácsi-Nagy Zoltán true 10013883 true Takácsi Nagy Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221504 /api/authorship/126221504 10 0.077 false false false Author 10013383 /api/author/10013383 Polgár Csaba true 10013383 true Polgár Csaba true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221505 /api/authorship/126221505 11 0.077 false false false Author 10020433 /api/author/10020433 Kocsis Zsuzsa true 10020433 true Kocsis Zsuzsa true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221506 /api/authorship/126221506 12 0.077 false false false Author 10044386 /api/author/10044386 Major Tibor true 10044386 true Major Tibor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126221507 /api/authorship/126221507 13 0.077 false true true Author 10030572 /api/author/10030572 Ágoston Péter Zoltán true 10030572 true Ágoston Péter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 29259130 /api/publicationidentifier/29259130 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1007/s00066-025-02397-w https://doi.org/10.1007/s00066-025-02397-w false true PublicationIdentifier 29273095 /api/publicationidentifier/29273095 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001466973200001 https://www.webofscience.com/wos/woscc/full-record/001466973200001 true true PublicationIdentifier 29259131 /api/publicationidentifier/29259131 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105002601937 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105002601937 false true PublicationIdentifier 29259129 /api/publicationidentifier/29259129 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40232382 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40232382&dopt=Abstract false true Classification 12306 /api/classification/12306 true true Keyword 3693 /api/keyword/3693 true 3693 true Keyword 1008662 /api/keyword/1008662 true 1008662 true Keyword 1769393 /api/keyword/1769393 true true Keyword 2089968 /api/keyword/2089968 true true Keyword 3857987 /api/keyword/3857987 true true SjrRating 11609356 /api/sjrrating/11609356 203 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2730 /api/classificationexternal/2730 true 2730 true Q2 DIRECT true true /api/publication/36100212 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Varga Levente </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10083670"><a href="/gui2/?type=authors&mode=browse&sel=10083670" target="_blank">Gáldi Ádám (<span class="authorship-author-name">Gáldi Ádám</span> <span class="authorAux-mtmt"> Orvos fizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/Doktori Iskola</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10075032"><a href="/gui2/?type=authors&mode=browse&sel=10075032" target="_blank">Szegedi Domonkos (<span class="authorship-author-name">Szegedi Domonkos</span> <span class="authorAux-mtmt"> orvosi fizikus</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Budapesti Műszaki és Gazdaságtudományi Egyetem">BME</span>/<span title="Természettudományi Kar">TTK</span>/<span title="Nukleáris Technikai Intézet">NTI</span>/Nukleáris Technika Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10042833"><a href="/gui2/?type=authors&mode=browse&sel=10042833" target="_blank">Herein András (<span class="authorship-author-name">Herein András</span> <span class="authorAux-mtmt"> Fizikai</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Pulugor Dóra </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10085931"><a href="/gui2/?type=authors&mode=browse&sel=10085931" target="_blank">Nahaji István (<span class="authorship-author-name">Nahaji István</span> <span class="authorAux-mtmt"> Sugárterápia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10058289"><a href="/gui2/?type=authors&mode=browse&sel=10058289" target="_blank">Gesztesi László (<span class="authorship-author-name">Gesztesi László</span> <span class="authorAux-mtmt"> Sugárterápia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10064469"><a href="/gui2/?type=authors&mode=browse&sel=10064469" target="_blank">Jorgo Kliton (<span class="authorship-author-name">Jorgo Kliton</span> <span class="authorAux-mtmt"> Onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013883"><a href="/gui2/?type=authors&mode=browse&sel=10013883" target="_blank">Takácsi Nagy Zoltán (<span class="authorship-author-name">Takácsi-Nagy Zoltán</span> <span class="authorAux-mtmt"> Sugárterápia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013383"><a href="/gui2/?type=authors&mode=browse&sel=10013383" target="_blank">Polgár Csaba (<span class="authorship-author-name">Polgár Csaba</span> <span class="authorAux-mtmt"> Sugárterápia, klinikai onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10020433"><a href="/gui2/?type=authors&mode=browse&sel=10020433" target="_blank">Kocsis Zsuzsa (<span class="authorship-author-name">Kocsis Zsuzsa</span> <span class="authorAux-mtmt"> sugárbiológia, onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10044386"><a href="/gui2/?type=authors&mode=browse&sel=10044386" target="_blank">Major Tibor (<span class="authorship-author-name">Major Tibor</span> <span class="authorAux-mtmt"> klinikai sugárfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10030572"><a href="/gui2/?type=authors&mode=browse&sel=10030572" target="_blank">Ágoston Péter ✉ (<span class="authorship-author-name">Ágoston Péter Zoltán</span> <span class="authorAux-mtmt"> Sugárterápia, onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36100212" target="_blank">Reduction of the planning target volume with daily online adaptive radiotherapy in bladder cancer.</a></div> <div> <span class="journal-title">STRAHLENTHERAPIE UND ONKOLOGIE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0179-7158">0179-7158</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1439-099X">1439-099X</a>)</span>: <span class="journal-volume">201</span> <span class="journal-issue">11</span> <span class="page"> pp 1162-1169 </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1007/s00066-025-02397-w" target="_blank" href="https://doi.org/10.1007/s00066-025-02397-w"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001466973200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001466973200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105002601937" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105002601937"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40232382" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40232382&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Oncology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Radiology, Nuclear Medicine and Imaging&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 5</span> | Független: 5 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 4 | Scopus jelölt:&nbsp;5 | WoS/Scopus jelölt:&nbsp;5 | DOI jelölt:&nbsp;5 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36100212</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (National Tumor Biology Laboratory (2022–2.1.1-NL-2022-00010))), Hungarian Thematic Excellence Program((TKP2021-EGA-44)) </div> <div class="lastModified">Utolsó módosítás: 2026.09.09. 10:29 Csajbók Edit (SE admin4) </div> </div></div>