https://m2.mtmt.hu/ hun 2026-04-16 22:46 JournalArticle 36089318 VALIDATED true Export Date: 13 April 2025; Cited By: 0; Correspondence Address: P. Martinez; Association Cancer et Métabolisme, Nîmes, 30000, France; email: pierrick.martinez@ifoga.fr; CODEN: SECBE 0 false 2026-04-16T12:18:15.630+0000 2026-04-16T12:06:53.412+0000 2025-04-13T21:02:16.737+0000 true 10093553 Fi Tamás /api/admin/10093553 Admin true 2026-04-16T12:06:52.794+0000 2025-09-17T12:59:12.167+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 2025-12-26T06:13:07.077+0000 true 521 Szuper Admin /api/admin/521 Admin true false false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Martinez, P. Vitamin D: What role in obesity-related cancer? true true /api/journal/10077 REVIEWED true false 10077 false 10077 true 1044-579X 1096-3650 Journal FOREIGN 112 135 149 135 15 2025 Obesity is an important risk factor for incidence and death for many types of cancer. Vitamin D reduces risk of incidence and death for many types of cancer. This review outlines the mechanisms by which obesity increases risk of cancer, how vitamin D reduces risk of cancer, and the extent to which vitamin D counters the effects of obesity in cancer. Vitamin D is a partial ally against some of obesity's pro-carcinogenic effects, notably by reducing inflammation and regulating sex hormone receptors, leptin resistance, cellular energy metabolism, the microbiome, and hypoxia. However, it can act stronger in against the renin-angiotensin system, insulin resistance, and oxidative stress in cancer. Additionally, excess fat tissue sequesters vitamin D and, along with its dilution in increased body volume, further reduces its bioavailability and serum concentration, limiting its protective effects against cancer. In conclusion, while vitamin D cannot reverse obesity, it plays a significant role in mitigating its pro-carcinogenic effects by targeting several mechanisms. © 2025 2025 true true true false false NONE 2026-04-16 false 0 0 0 0 0 0 0 0 0 0 0 0 4 4 D1 false false false false 2025-07-12T21:02:35.325+0000 13 75 0 2 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 126153421 /api/authorship/126153421 1 0.5 true false false Martinez P. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 126153422 /api/authorship/126153422 2 0.5 false true false Grant W.B. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 29233595 /api/publicationidentifier/29233595 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1016/j.semcancer.2025.03.007 https://doi.org/10.1016/j.semcancer.2025.03.007 false true PublicationIdentifier 29642152 /api/publicationidentifier/29642152 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001467686900001 https://www.webofscience.com/wos/woscc/full-record/001467686900001 false true PublicationIdentifier 29233594 /api/publicationidentifier/29233594 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105002027435 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105002027435 false true PublicationIdentifier 29642153 /api/publicationidentifier/29642153 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40194750 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40194750&dopt=Abstract false true PublicationIdentifier 31846351 /api/publicationidentifier/31846351 PlainSource 40 /api/publicationsource/40 PublicationSourceType 10006 /api/publicationsourcetype/10006 true true true Egyéb URL Other URL @@@ true true 40 true NONE IDENTICAL https://www.scopus.com/pages/publications/105002027435?origin=resultslist https://www.scopus.com/pages/publications/105002027435?origin=resultslist false true Keyword 52 /api/keyword/52 true 52 true Keyword 56 /api/keyword/56 true 56 true Keyword 64 /api/keyword/64 true 64 true Keyword 64 /api/keyword/64 true 64 true Keyword 453 /api/keyword/453 true 453 true Keyword 643 /api/keyword/643 true 643 true Keyword 2981 /api/keyword/2981 true 2981 true Keyword 3118 /api/keyword/3118 true 3118 true Keyword 3122 /api/keyword/3122 true 3122 true Keyword 4537 /api/keyword/4537 true 4537 true Keyword 4591 /api/keyword/4591 true 4591 true Keyword 4817 /api/keyword/4817 true 4817 true Keyword 4817 /api/keyword/4817 true 4817 true Keyword 11096 /api/keyword/11096 true 11096 true Keyword 11096 /api/keyword/11096 true 11096 true Keyword 12859 /api/keyword/12859 true 12859 true Keyword 15126 /api/keyword/15126 true 15126 true Keyword 17729 /api/keyword/17729 true 17729 true Keyword 17859 /api/keyword/17859 true 17859 true Keyword 20181 /api/keyword/20181 true 20181 true Keyword 1009495 /api/keyword/1009495 true 1009495 true Keyword 1009495 /api/keyword/1009495 true 1009495 true Keyword 1009727 /api/keyword/1009727 true 1009727 true Keyword 1013410 /api/keyword/1013410 true 1013410 true Keyword 1013410 /api/keyword/1013410 true 1013410 true Keyword 1020011 /api/keyword/1020011 true 1020011 true Keyword 1020066 /api/keyword/1020066 true 1020066 true Keyword 1027681 /api/keyword/1027681 true 1027681 true Keyword 1038103 /api/keyword/1038103 true 1038103 true Keyword 1458829 /api/keyword/1458829 true 1458829 true Keyword 1506920 /api/keyword/1506920 true true Keyword 1560406 /api/keyword/1560406 true true Keyword 2002324 /api/keyword/2002324 true true Keyword 2014641 /api/keyword/2014641 true true Keyword 2014641 /api/keyword/2014641 true true Keyword 2157528 /api/keyword/2157528 true true SjrRating 11562997 /api/sjrrating/11562997 18 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1306 /api/classificationexternal/1306 true 1306 true D1 FROM_LAST_YEAR true true /api/publication/36089318 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Martinez P. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Grant W.B. </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36089318" target="_blank">Vitamin D: What role in obesity-related cancer?</a></div> <div> <span class="journal-title">SEMINARS IN CANCER BIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1044-579X">1044-579X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1096-3650">1096-3650</a>)</span>: <span class="journal-volume">112</span> <span class="page"> pp 135-149 </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1016/j.semcancer.2025.03.007" target="_blank" href="https://doi.org/10.1016/j.semcancer.2025.03.007"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001467686900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001467686900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105002027435" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105002027435"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40194750" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40194750&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://www.scopus.com/pages/publications/105002027435?origin=resultslist" target="_blank" href="https://www.scopus.com/pages/publications/105002027435?origin=resultslist"> Egyéb URL </a> </span> </span> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36089318&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36089318</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Utolsó módosítás: 2026.04.16. 14:06 Fi Tamás (SE_AOK_Nepegeszsegtan_Admin5_FT, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Export Date: 13 April 2025; Cited By: 0; Correspondence Address: P. Martinez; Association Cancer et Métabolisme, Nîmes, 30000, France; email: pierrick.martinez@ifoga.fr; CODEN: SECBE</pre> </div></div>