https://m2.mtmt.hu/ hun 2026-10-24 16:05 JournalArticle 36084573 VALIDATED true 0 false 2026-10-18T13:07:26.399+0000 2025-07-29T07:36:33.277+0000 2025-04-10T08:35:11.684+0000 true 10071338 Molnár-Taga Márta /api/admin/10071338 Admin Molnár-Taga Márta (SE_AOK_1Bel_Onkol_Admin5_MTM, admin) true 2026-05-22T16:18:04.581+0000 2025-04-22T10:23:25.296+0000 true 10097128 Sass Dávid /api/admin/10097128 Admin Sass Dávid (SZTE admin5) true Admin 10099440 /api/admin/10099440 Csernyik Rita (MTMT központi admin) Csernyik Rita true true 2025-04-25T06:19:56.289+0000 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Tóth, Béla E. true true /api/journal/10016563 REVIEWED NUTRIENTS 2072-6643 true false 10016563 false 10016563 true 2072-6643 Journal FOREIGN 17 7 1246 1246 20 2025 Background/Objectives: Vitamin D deficiency is common in women with polycystic ovary syndrome (PCOS) and may be associated with metabolic and endocrine disorders as well as ovulatory dysfunction. Vitamin D supplementation may improve ovarian dysfunction and follicular development by effecting gene expression. The aim of the present study was to investigate the effects of vitamin D supplementation in women with PCOS through a prospective, randomized, two-phase, parallel design, placebo-controlled trial. Methods: We assessed the impact on ovarian morphology, cycle length, and ovulatory dysfunction. Transvaginal ultrasonography (TVUS) examinations and clinical laboratory assessments were conducted at the baseline, and again after 12 and 24 weeks. The participants received vitamin D (30,000 IU/week) or a placebo (without concurrent metformin use) for 12 weeks, supplemented with calcium, followed by an additional 12 weeks of vitamin D treatment. Results: The treatment resulted in improvements in ovarian morphology and regularity of menstrual cycles in more than half of the patients. Additionally, vitamin D3 was associated with a significant increase in the ovulation rate. A statistically significant reduction in mean testosterone levels was observed in the subgroup of patients with an LH/FSH ratio greater than 2. Conclusions: Our results suggest that vitamin D3 treatment could function as either a standalone or an adjunctive therapy in the management of PCOS. Funding 2051808 /api/funding/2051808 (PAT15-PCODD) false true true 2025 true true true false true false GOLD 2026-10-18 true https://doi.org/10.3390/nu17071246 9 0 9 7 2 9 9 8 9 9 9 7 7 7 2 0 9 7 9 7 0 3 3 Folyóiratcikk Journal Article 24 9 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 5 4 5 4 2026 0 4 3 4 3 D1 false 10024099,10011408 false false false 2025-04-09T08:35:19.072+0000 Belgyógyászati Klinika (SZTE / SZAOK); Belgyógyászati és Onkológiai Klinika (SE / AOK / K); Gyógyszerfelügyelet és Gyógyszergazdálkodási Ta... (DE / GYTK); Orálbiológiai Tanszék (SE / FOK); Szülészeti és Nőgyógyászati Intézet (DE / ÁOK) 8 35 5 9 0 true 10099440 Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 126133263 /api/authorship/126133263 Tóth, Béla E. ✉ [Tóth, Béla Ernő (orvostudományi- é...), szerző] Gyógyszerfelügyelet és Gyógyszergazdálkodási Ta... (DE / GYTK) 1 0.111 true false true Author 10036245 /api/author/10036245 Tóth Béla Ernő (orvostudományi- és gyógyszerkutatás) Tóth Béla Ernő true 10036245 true Tóth Béla E. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126133264 /api/authorship/126133264 Takács, István [Takács, István (Endokrinológia), szerző] Belgyógyászati és Onkológiai Klinika (SE / AOK / K) 2 0.111 false false false Author 10024031 /api/author/10024031 Takács István (Endokrinológia) Takács István true 10024031 true Takács István true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126133265 /api/authorship/126133265 Valkusz, Zsuzsanna [Valkusz, Zsuzsanna (belgyógyászat, en...), szerző] Belgyógyászati Klinika (SZTE / SZAOK) 3 0.111 false false false Author 10029231 /api/author/10029231 Valkusz Zsuzsanna (belgyógyászat, endokrinológia) Valkusz Zsuzsanna true 10029231 true Valkusz Zsuzsanna true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126133266 /api/authorship/126133266 Jakab, Attila [Jakab, Attila (Szülészet-nőgyógy...), szerző] Szülészeti és Nőgyógyászati Intézet (DE / ÁOK) 4 0.11111111 false false false Author 10011408 /api/author/10011408 Jakab Attila (Szülészet-nőgyógyászat) Jakab Attila true 10011408 true Jakab Attila true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126133267 /api/authorship/126133267 Fülöp, Zsanett 5 0.11111111 false false false Fülöp Zsanett true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126133268 /api/authorship/126133268 Kádár, Kristóf [Kádár, Kristóf György (Orálbiológia), szerző] Orálbiológiai Tanszék (SE / FOK) 6 0.111 false false false Author 10018991 /api/author/10018991 Kádár Kristóf György (Orálbiológia) Kádár Kristóf György true 10018991 true Kádár Kristóf true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126133269 /api/authorship/126133269 Putz, Zsuzsanna [Putz, Zsuzsanna (Belgyógyászat, di...), szerző] Belgyógyászati és Onkológiai Klinika (SE / AOK / K) 7 0.111 false false false Author 10013989 /api/author/10013989 Putz Zsuzsanna (Belgyógyászat, diabetológia, klinikofarmakológia) Putz Zsuzsanna true 10013989 true Putz Zsuzsanna true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126133270 /api/authorship/126133270 Kósa, János Pál [Kósa, János (molekuláris biológia), szerző] Belgyógyászati és Onkológiai Klinika (SE / AOK / K) 8 0.111 false false false Author 10024099 /api/author/10024099 Kósa János (molekuláris biológia) Kósa János true 10024099 true Kósa János Pál true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 126133271 /api/authorship/126133271 Lakatos, Péter [Lakatos, Péter (Osteológia, endok...), szerző] Belgyógyászati és Onkológiai Klinika (SE / AOK / K) 9 0.111 false true false Author 10012016 /api/author/10012016 Lakatos Péter (Osteológia, endokrinológia, molekuláris biológia) Lakatos Péter true 10012016 true Lakatos Péter true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 29222482 /api/publicationidentifier/29222482 DOI: 10.3390/nu17071246 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/nu17071246 https://doi.org/10.3390/nu17071246 false true PublicationIdentifier 29260737 /api/publicationidentifier/29260737 WoS: 001463722100001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40219003&dopt=Abstract false true PublicationIdentifier 30051541 /api/publicationidentifier/30051541 Egyéb URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-105002364240&doi=10.3390%2Fnu17071246&partnerID=40&md5=4dca1e6c0b8f730a49f015609c7792af PlainSource 40 /api/publicationsource/40 Egyéb URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true NONE IDENTICAL https://www.scopus.com/inward/record.uri?eid=2-s2.0-105002364240&doi=10.3390%2Fnu17071246&partnerID=40&md5=4dca1e6c0b8f730a49f015609c7792af https://www.scopus.com/inward/record.uri?eid=2-s2.0-105002364240&doi=10.3390%2Fnu17071246&partnerID=40&md5=4dca1e6c0b8f730a49f015609c7792af false true PublicationIdentifier 31263864 /api/publicationidentifier/31263864 Egyéb URL: https://www.mdpi.com/2072-6643/17/7/1246 PlainSource 40 /api/publicationsource/40 Egyéb URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true IDENTICAL https://www.mdpi.com/2072-6643/17/7/1246 https://www.mdpi.com/2072-6643/17/7/1246 false true SjrRating 11583198 /api/sjrrating/11583198 sjr:D1 (2025) Scopus - Food Science NUTRIENTS 2072-6643 25 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1106 /api/classificationexternal/1106 Scopus - Food Science true 1106 true D1 DIRECT true true Reference 65294907 /api/reference/65294907 1. 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(2025) NUTRIENTS 2072-6643 17 7<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10036245"><a href="/gui2/?type=authors&mode=browse&sel=10036245" target="_blank">Tóth Béla E. ✉ (<span class="authorship-author-name">Tóth Béla Ernő</span> <span class="authorAux-mtmt"> orvostudományi- és gyógyszerkutatás</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Gyógyszerfelügyelet és Gyógyszergazdálkodási Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024031"><a href="/gui2/?type=authors&mode=browse&sel=10024031" target="_blank">Takács István (<span class="authorship-author-name">Takács István</span> <span class="authorAux-mtmt"> Endokrinológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Onkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10029231"><a href="/gui2/?type=authors&mode=browse&sel=10029231" target="_blank">Valkusz Zsuzsanna (<span class="authorship-author-name">Valkusz Zsuzsanna</span> <span class="authorAux-mtmt"> belgyógyászat, endokrinológia</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Szent-Györgyi Albert Orvostudományi Kar">SZAOK</span>/Belgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10011408"><a href="/gui2/?type=authors&mode=browse&sel=10011408" target="_blank">Jakab Attila (<span class="authorship-author-name">Jakab Attila</span> <span class="authorAux-mtmt"> Szülészet-nőgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Szülészeti és Nőgyógyászati Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Fülöp Zsanett </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10018991"><a href="/gui2/?type=authors&mode=browse&sel=10018991" target="_blank">Kádár Kristóf (<span class="authorship-author-name">Kádár Kristóf György</span> <span class="authorAux-mtmt"> Orálbiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Fogorvostudományi Kar">FOK</span>/Orálbiológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013989"><a href="/gui2/?type=authors&mode=browse&sel=10013989" target="_blank">Putz Zsuzsanna (<span class="authorship-author-name">Putz Zsuzsanna</span> <span class="authorAux-mtmt"> Belgyógyászat, diabetológia, klinikofarmakológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Onkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024099"><a href="/gui2/?type=authors&mode=browse&sel=10024099" target="_blank">Kósa János Pál (<span class="authorship-author-name">Kósa János</span> <span class="authorAux-mtmt"> molekuláris biológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Onkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012016"><a href="/gui2/?type=authors&mode=browse&sel=10012016" target="_blank">Lakatos Péter (<span class="authorship-author-name">Lakatos Péter</span> <span class="authorAux-mtmt"> Osteológia, endokrinológia, molekuláris biológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Onkológiai Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;36084573" target="_blank">Effects of Vitamin D3 Treatment on Polycystic Ovary Symptoms: A Prospective Double-Blind Two-Phase Randomized Controlled Clinical Trial</a></div> <div> <span class="journal-title">NUTRIENTS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2072-6643">2072-6643</a>)</span>: <span class="journal-volume">17</span> <span class="journal-issue">7</span> <span class="page"> Paper 1246. 20 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" 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jelölt:&nbsp;9 | DOI jelölt:&nbsp;9 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;36084573&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 36084573</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (PAT15-PCODD) </div> <div class="lastModified">Utolsó módosítás: 2025.07.29. 09:36 Száldobágyi-Tóth Bettina (DE admin4) </div> <div class="lockedBy">Központi kezelésű 2025.04.25. 08:19 Csernyik Rita (MTMT központi admin) </div> </div></div>