https://m2.mtmt.hu/ hun 2026-09-22 06:50 JournalArticle 35794399 VALIDATED true Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti st. 12., Pécs, H-7624, Hungary Department of Pharmacognosy, Semmelweis University, Üllői st. 26., Budapest, H-1085, Hungary Centre for Translational Medicine, Semmelweis University, Üllői st. 26., Budapest, H-1085, Hungary Institute of Clinical Pharmacy, Medical School, University of Pécs, Szigeti st. 12., Pécs, H-7624, Hungary Institute of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, University of Pécs, Rókus str. 2., Pécs, H-7624, Hungary Export Date: 03 June 2026; Cited By: 3; Correspondence Address: G. Schneider; Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Pécs, Szigeti st. 12., H-7624, Hungary; email: schneider.gyorgy@pte.hu 0 false 2026-08-25T12:35:23.111+0000 2026-06-03T02:59:19.709+0000 2025-02-27T19:43:29.240+0000 true 10015206 Áncsán Gizella /api/admin/10015206 Admin Áncsán Gizella (SE admin) true 10015206 2026-08-25T12:33:49.390+0000 2025-04-11T07:17:24.113+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Schneider, György true true /api/journal/10050685 REVIEWED ANTIBIOTICS 2079-6382 2079-6382 true false 10050685 false 10050685 true 2079-6382 2079-6382 Journal FOREIGN 14 3 241 241 13 2025 Background: Due to their antibacterial activities, essential oils can be potential alternatives to antibiotics in certain cases. West Indian lemongrass (Cymbopogon citratus) essential oil (LEO) is effective against a broad range of bacteria by inhibiting spore formation, and is considered safe. In this study, we demonstrated its therapeutical potential in the treatment of pitted keratolysis (PK), a superficial skin infection affecting the pressure-bearing areas of plantar surfaces. Methods: For in vitro antibacterial efficacy testing, LEO was mixed into different ointment bases, including Hydrogelum methylcellulose FoNo VIII., Ungentum oleosum FoNo VIII. (Ung. oleoso), Unguentum stearini FoNo VIII. (Ung. stearin), and Vaselinum cholesterinatum FoNo VIII. (Vasel. cholest.), at different concentrations of 1, 3, and 5%. These formulations were tested on representatives of three bacterial species associated with PK: Kytococcus sedentarius, Dermatophilus congolensis, and Bacillus thuringiensis. Results: In the in vitro tests, Hydrogelum methylcellulose (HM) gel best supported the antibacterial effects of LEO, reducing the number of living bacteria on agar plates by 4–5 orders of magnitude in a concentration-dependent manner during the 30 min exposure times. This was also confirmed by the Franz diffusion cell drug release test; after 30 min, several active compounds could be detected in the HM samples, in contrast to the other bases. Shelf-life experiments showed that the HM base supported the antibacterial features of 3% LEO for at least 2 years without significant loss of efficacy. Conclusions: Our study highlights that ointments containing essential oils potentially have a place in the treatment of PK. Therefore, antibiotics may potentially be replaced for the treatment of PK, thereby reducing environmental antibiotic pressure, which is one of the driving forces behind the spread of antibiotic resistance. true true 2025 true true true false true false GOLD 2026-08-25 true https://doi.org/10.3390/antibiotics14030241 4 0 4 4 0 4 4 3 4 4 4 4 4 4 0 0 4 4 4 4 0 4 4 Folyóiratcikk Journal Article 24 4 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 1 1 1 2026 0 3 3 3 3 D1 false false false false 2025-03-13T10:12:54.535+0000 Farmakognóziai Intézet (SE / GYTK); Gyógyszertechnológiai és Biofarmáciai Intézet (PTE / GYTK); Orvosi Mikrobiológiai és Immunitástani Intézet (PTE / ÁOK); Transzlációs Medicina Központ (SE / KSZE) 6 25 4 8 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 123555374 /api/authorship/123555374 Schneider, György ✉ [Schneider, György (Bakteriológia), szerző] Orvosi Mikrobiológiai és Immunitástani Intézet (PTE / ÁOK) 1 0.125 true false true Author 10014098 /api/author/10014098 Schneider György (Bakteriológia) Schneider György true 10014098 true Schneider György true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 123555375 /api/authorship/123555375 Schweitzer, Bettina [Schweitzer, Bettina (Biológia), szerző] Orvosi Mikrobiológiai és Immunitástani Intézet (PTE / ÁOK) 2 0.125 false false false Author 10072581 /api/author/10072581 Schweitzer Bettina (Biológia) Schweitzer Bettina true true Schweitzer Bettina true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 123555376 /api/authorship/123555376 Steinbach S., Anita [Seres-Steinbach, Anita (Mikrobiológia), szerző] Orvosi Mikrobiológiai és Immunitástani Intézet (PTE / ÁOK) 3 0.125 false false false Author 10088790 /api/author/10088790 Seres-Steinbach Anita (Mikrobiológia) Seres-Steinbach Anita true true Steinbach S. Anita true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 123555377 /api/authorship/123555377 Hodován, Ágnes S. 4 0.125 false false false Hodován Ágnes S. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 123555378 /api/authorship/123555378 Horváth, Marianna [Horváth, Marianna (Mikrobiológia), szerző] Orvosi Mikrobiológiai és Immunitástani Intézet (PTE / ÁOK) 5 0.125 false false false Author 10055526 /api/author/10055526 Horváth Marianna (Mikrobiológia) Horváth Marianna true 10055526 true Horváth Marianna true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 123555379 /api/authorship/123555379 Bakó, Eszter [Bakó, Eszter (farmakognózia), szerző] Farmakognóziai Intézet (SE / GYTK); Transzlációs Medicina Központ (SE / KSZE) 6 0.125 false false false Author 10075162 /api/author/10075162 Bakó Eszter (farmakognózia) Bakó Eszter true true Bakó Eszter true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 123555380 /api/authorship/123555380 Mayer, Anna 7 0.125 false false false Mayer Anna true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 123555381 /api/authorship/123555381 Pál, Szilárd [Pál, Szilárd (Gyógyszertechnológia), szerző] Gyógyszertechnológiai és Biofarmáciai Intézet (PTE / GYTK) 8 0.125 false true false Author 10016684 /api/author/10016684 Pál Szilárd (Gyógyszertechnológia) Pál Szilárd true 10016684 true Pál Szilárd true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 28508121 /api/publicationidentifier/28508121 DOI: 10.3390/antibiotics14030241 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/antibiotics14030241 https://doi.org/10.3390/antibiotics14030241 false true PublicationIdentifier 29212400 /api/publicationidentifier/29212400 WoS: 001453543500001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001453543500001 https://www.webofscience.com/wos/woscc/full-record/001453543500001 false true PublicationIdentifier 29212399 /api/publicationidentifier/29212399 Scopus: 105001351155 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 105001351155 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105001351155 false true PublicationIdentifier 29191365 /api/publicationidentifier/29191365 PubMed: 40149054 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 40149054 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40149054&dopt=Abstract false true PublicationIdentifier 29602912 /api/publicationidentifier/29602912 Egyéb URL: https://www.mdpi.com/2079-6382/14/3/241 PlainSource 40 /api/publicationsource/40 Egyéb URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true IDENTICAL https://www.mdpi.com/2079-6382/14/3/241 https://www.mdpi.com/2079-6382/14/3/241 false true SjrRating 11612611 /api/sjrrating/11612611 sjr:D1 (2025) Scopus - Pharmacology, Toxicology and Pharmaceutics (miscellaneous) ANTIBIOTICS 2079-6382 2079-6382 5 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 3001 /api/classificationexternal/3001 Scopus - Pharmacology, Toxicology and Pharmaceutics (miscellaneous) true 3001 true D1 DIRECT true true Reference 64285680 /api/reference/64285680 1. 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(2025) ANTIBIOTICS 2079-6382 2079-6382 14 3<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10014098"><a href="/gui2/?type=authors&mode=browse&sel=10014098" target="_blank">Schneider György ✉ (<span class="authorship-author-name">Schneider György</span> <span class="authorAux-mtmt"> Bakteriológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Orvosi Mikrobiológiai és Immunitástani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10072581"><a href="/gui2/?type=authors&mode=browse&sel=10072581" target="_blank">Schweitzer Bettina (<span class="authorship-author-name">Schweitzer Bettina</span> <span class="authorAux-mtmt"> Biológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Orvosi Mikrobiológiai és Immunitástani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10088790"><a href="/gui2/?type=authors&mode=browse&sel=10088790" target="_blank">Steinbach S. Anita (<span class="authorship-author-name">Seres-Steinbach Anita</span> <span class="authorAux-mtmt"> Mikrobiológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Orvosi Mikrobiológiai és Immunitástani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hodován Ágnes S. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10055526"><a href="/gui2/?type=authors&mode=browse&sel=10055526" target="_blank">Horváth Marianna (<span class="authorship-author-name">Horváth Marianna</span> <span class="authorAux-mtmt"> Mikrobiológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Orvosi Mikrobiológiai és Immunitástani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10075162"><a href="/gui2/?type=authors&mode=browse&sel=10075162" target="_blank">Bakó Eszter (<span class="authorship-author-name">Bakó Eszter</span> <span class="authorAux-mtmt"> farmakognózia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Farmakognóziai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Mayer Anna </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016684"><a href="/gui2/?type=authors&mode=browse&sel=10016684" target="_blank">Pál Szilárd (<span class="authorship-author-name">Pál Szilárd</span> <span class="authorAux-mtmt"> Gyógyszertechnológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Gyógyszertechnológiai és Biofarmáciai Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35794399" target="_blank">The Therapeutic Potential of West Indian Lemongrass (Cymbopogon citratus) Essential Oil-Based Ointment in the Treatment of Pitted Keratolysis</a></div> <div> <span class="journal-title">ANTIBIOTICS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2079-6382">2079-6382</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2079-6382">2079-6382</a>)</span>: <span class="journal-volume">14</span> <span class="journal-issue">3</span> <span class="page"> Paper 241. 13 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/antibiotics14030241" target="_blank" href="https://doi.org/10.3390/antibiotics14030241"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001453543500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001453543500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="105001351155" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-105001351155"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="40149054" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=40149054&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="https://www.mdpi.com/2079-6382/14/3/241" target="_blank" href="https://www.mdpi.com/2079-6382/14/3/241"> Egyéb URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmacology, Toxicology and Pharmaceutics (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Infectious Diseases&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Microbiology (medical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Microbiology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmacology (medical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 4</span> | Független: 4 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 3 | Scopus jelölt:&nbsp;4 | WoS/Scopus jelölt:&nbsp;4 | DOI jelölt:&nbsp;4 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;35794399&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 35794399</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2026.06.03. 04:59 Milánkovics Róbert (PTE ÁOK admin 4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti st. 12., Pécs, H-7624, Hungary Department of Pharmacognosy, Semmelweis University, Üllői st. 26., Budapest, H-1085, Hungary Centre for Translational Medicine, Semmelweis University, Üllői st. 26., Budapest, H-1085, Hungary Institu...</pre> </div></div>