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      <abstractText>Background/Objectives: Our study aimed to determine the accuracy of the artificial intelligence-based Diagnocat system (DC) in detecting periapical lesions (PL) on panoramic radiographs (PRs). Methods: 616 teeth were selected from 357 panoramic radiographs, including 308 teeth with clearly visible periapical radiolucency and 308 without any periapical lesion. Three groups were generated: teeth with radiographic signs of caries (Group 1), teeth with coronal restoration (Group 2), and teeth with root canal filling (Group 3). The PRs were uploaded to the Diagnocat system for evaluation. The performance of the convolutional neural network in detecting PLs was assessed by its sensitivity, specificity, and positive and negative predictive values, as well as the diagnostic accuracy value. We investigated the possible effect of the palatoglossal air space (PGAS) on the evaluation of the AI tool. Results: DC identified periapical lesions in 240 (77.9%) cases out of the 308 teeth with PL and detected no PL in 68 (22.1%) teeth with PL. The AI-based system detected no PL in any of the groups without PL. The overall sensitivity, specificity, and diagnostic accuracy of DC were 0.78, 1.00, and 0.89, respectively. Considering these parameters for each group, Group 2 showed the highest values at 0.84, 1.00, and 0.95, respectively. Fisher’s Exact test showed that PGAS does not significantly affect (p = 1) the detection of PL in the upper teeth. The AI-based system showed lower probability values for detecting PL in the case of central incisors, wisdom teeth, and canines. The sensitivity and diagnostic accuracy of DC for detecting PL on canines showed lower values at 0.27 and 0.64, respectively. Conclusions: The CNN-based Diagnocat system can support the diagnosis of PL on PRs and serves as a decision-support tool during radiographic assessments.</abstractText>
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      <label>Szabó Viktor et al. Deep Learning-Based Periapical Lesion Detection on Panoramic Radiographs. (2025) DIAGNOSTICS 2075-4418 2075-4418 15 4</label><template>&lt;div class=&quot;JournalArticle Publication short-list&quot;&gt; &lt;div class=&quot;authors&quot;&gt; &lt;span class=&quot;author-name&quot; mtid=&quot;10089827&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10089827&quot; target=&quot;_blank&quot;&gt;Szabó, Viktor ✉&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10092814&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10092814&quot; target=&quot;_blank&quot;&gt;Orhan, Kaan&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10009883&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10009883&quot; target=&quot;_blank&quot;&gt;Dobó-Nagy, Csaba&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; 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mtid=&quot;35791240&quot; target=&quot;_blank&quot;&gt;Deep Learning-Based Periapical Lesion Detection on Panoramic Radiographs&lt;/a&gt;&lt;/div&gt; &lt;div class=&quot;pub-info&quot;&gt; &lt;span class=&quot;journal-title&quot;&gt;DIAGNOSTICS&lt;/span&gt; &lt;span class=&quot;journal-volume&quot;&gt;15&lt;/span&gt; : &lt;span class=&quot;journal-issue&quot;&gt;4&lt;/span&gt; &lt;span class=&quot;page&quot;&gt; Paper: 510 , 11 p. &lt;/span&gt; &lt;span class=&quot;year&quot;&gt;(2025)&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;pub-end&quot;&gt;&lt;div class=&quot;identifier-list&quot;&gt; &lt;span class=&quot;identifiers&quot;&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;10.3390/diagnostics15040510&quot; target=&quot;_blank&quot; href=&quot;https://doi.org/10.3390/diagnostics15040510&quot;&gt; DOI &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; 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Egyeztetett &lt;/span&gt;&lt;/span&gt; &lt;span class=&quot;pub-core&quot;&gt;Forrás &lt;/span&gt; &lt;span class=&quot;pub-type&quot;&gt;Folyóiratcikk (Szakcikk ) &lt;/span&gt; &lt;!-- &amp;&amp; !record.category.scientific --&gt; &lt;span class=&quot;pub-category&quot;&gt;Tudományos&lt;/span&gt; &lt;div class=&quot;publication-citation&quot; style=&quot;margin-left: 0.5cm;&quot;&gt; &lt;span title=&quot;Nyilvános idézőközlemények összesen, említések nélkül&quot; class=&quot;citingPub-count&quot;&gt;Nyilvános idéző összesen: 24&lt;/span&gt; | Független: 24 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 16 | Scopus jelölt:&amp;nbsp;22 | WoS/Scopus jelölt:&amp;nbsp;22 | DOI jelölt:&amp;nbsp;24 &lt;/div&gt; &lt;/div&gt; &lt;/div&gt; &lt;/div&gt;</template><template2>&lt;div class=&quot;JournalArticle Publication long-list&quot;&gt; &lt;div class=&quot;authors&quot;&gt; &lt;img title=&quot;Forrásközlemény&quot; style=&quot;float: left&quot; src=&quot;/frontend/resources/grid/publication-core-icon.png&quot;&gt; &lt;div class=&quot;autype autype0&quot;&gt; &lt;span class=&quot;author-name&quot; mtid=&quot;10089827&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10089827&quot; target=&quot;_blank&quot;&gt;Szabó Viktor ✉ (&lt;span class=&quot;authorship-author-name&quot;&gt;Szabó Viktor&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Endodontia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Fogorvostudományi Kar&quot;&gt;FOK&lt;/span&gt;/Orális Diagnosztikai Tanszék&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10092814&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10092814&quot; target=&quot;_blank&quot;&gt;Orhan Kaan (&lt;span class=&quot;authorship-author-name&quot;&gt;Orhan Kaan&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Fogorvostudomány&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Fogorvostudományi Kar&quot;&gt;FOK&lt;/span&gt;/Orális Diagnosztikai Tanszék&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10009883&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10009883&quot; target=&quot;_blank&quot;&gt;Dobó-Nagy Csaba (&lt;span class=&quot;authorship-author-name&quot;&gt;Dobó-Nagy Csaba&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Fogászati radiológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Fogorvostudományi Kar&quot;&gt;FOK&lt;/span&gt;/Orális Diagnosztikai Tanszék&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10031347&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10031347&quot; target=&quot;_blank&quot;&gt;Veres Dániel Sándor (&lt;span class=&quot;authorship-author-name&quot;&gt;Veres Dániel&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Biofizika&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Intézet&quot;&gt;I&lt;/span&gt;/Biofizikai és Sugárbiológiai Intézet&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; &gt;Manulis David &lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; &gt;Ezhov Matvey &lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; &gt;Sanders Alex &lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10054818&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10054818&quot; target=&quot;_blank&quot;&gt;Szabó Bence Tamás (&lt;span class=&quot;authorship-author-name&quot;&gt;Szabó Bence Tamás&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Fogászati radiológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Fogorvostudományi Kar&quot;&gt;FOK&lt;/span&gt;/Orális Diagnosztikai Tanszék&lt;/span&gt; &lt;/div&gt; &lt;/div&gt; &lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;35791240&quot; target=&quot;_blank&quot;&gt;Deep Learning-Based Periapical Lesion Detection on Panoramic Radiographs&lt;/a&gt;&lt;/div&gt; &lt;div&gt; &lt;span class=&quot;journal-title&quot;&gt;DIAGNOSTICS&lt;/span&gt; &lt;span class=&quot;journal-issn&quot;&gt;(&lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/2075-4418&quot;&gt;2075-4418&lt;/a&gt; &lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/2075-4418&quot;&gt;2075-4418&lt;/a&gt;)&lt;/span&gt;: &lt;span class=&quot;journal-volume&quot;&gt;15&lt;/span&gt; &lt;span class=&quot;journal-issue&quot;&gt;4&lt;/span&gt; &lt;span class=&quot;page&quot;&gt; Paper 510. 11 p. &lt;/span&gt; &lt;span class=&quot;year&quot;&gt;(2025)&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;pub-footer&quot;&gt;  &lt;span class=&quot;language&quot; xmlns=&quot;http://www.w3.org/1999/html&quot;&gt;Nyelv: Angol | &lt;/span&gt; &lt;span class=&quot;identifiers&quot;&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;10.3390/diagnostics15040510&quot; target=&quot;_blank&quot; href=&quot;https://doi.org/10.3390/diagnostics15040510&quot;&gt; DOI &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;001433219900001&quot; target=&quot;_blank&quot; href=&quot;https://www.webofscience.com/wos/woscc/full-record/001433219900001&quot;&gt; WoS &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;85218887719&quot; target=&quot;_blank&quot; href=&quot;http://www.scopus.com/record/display.url?origin=inward&amp;eid=2-s2.0-85218887719&quot;&gt; Scopus &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;40002661&quot; target=&quot;_blank&quot; href=&quot;http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=40002661&amp;dopt=Abstract&quot;&gt; PubMed &lt;/a&gt; &lt;/span&gt; &lt;/span&gt; &lt;OnlyViewableByAuthor&gt;&lt;div class=&quot;ratings&quot;&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Clinical Biochemistry&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q2&lt;/div&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Internal Medicine&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q2&lt;/div&gt; &lt;/div&gt;&lt;/OnlyViewableByAuthor&gt; 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