(Open access funding provided by Semmelweis University)
Szakterületek:
Kettes típusú diabetesz (diabétesz mellitusz)
Affective temperaments are inherited parts of personality determining mood and activity,
affecting the management of somatic conditions. We aimed to investigate the association
between affective temperaments, depressive symptoms, and self-care (physical activity,
smoking, alcohol consumption), and their effect on glycemic control, among patients
with type 2 diabetes (T2DM) in general practice, in a cross-sectional study enrolling
338 consecutive patients from six primary care practices in Hungary. A self-administered
questionnaire (history, anthropometric, socioeconomic, laboratory parameters), the
Beck Depression Inventory (BDI), the Hamilton Anxiety Scale, and the Temperament Evaluation
of Memphis, Pisa, Paris, and San Diego Autoquestionnaire were used. Cyclothymic affective
temperament determined HbA1c levels in regression analysis ( p = 0.002), and the
BDI score ( p = 0.048). In causal mediation analyses, cyclothymic affective temperament
was directly associated with higher HbA1c ( p = 0.008). Hyperthymic affective temperament
was indirectly associated with lower HbA1c, mediated by BDI ( p = 0.034). Depressive,
anxious, and irritable affective temperaments, and lifestyle factors were not associated
with HbA1c neither in regression nor in mediation analysis as direct or mediating
factors. Among primary care patients with T2DM, cyclothymic temperament correlates
with worse glycemic control, independently of depressive symptoms. Hyperthymic temperament
reduces depressive symptoms, thereby improving glycemic control. Identifying affective
temperaments may improve diabetes care.
