https://m2.mtmt.hu/ hun 2026-09-22 18:19 JournalArticle 35701376 VALIDATED true 0 false 2026-06-02T13:57:11.557+0000 2025-03-14T10:53:50.862+0000 2025-01-20T07:07:18.918+0000 true 10081340 Pirmann Tamás /api/admin/10081340 Admin true 2025-03-18T09:42:46.338+0000 2025-03-18T09:42:46.338+0000 2025-03-14T10:53:50.868+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType 104 true 10000359 true 1 /api/category/1 Category true 1 Màlyi, Ambrus Postoperative pancreatic fistula risk assessment using digital pathology based analyses at the parenchymal resection margin of the pancreas - Results from the randomized multicenter RECOPANC trial. true true /api/journal/10015956 REVIEWED true false 10015956 false 10015956 true 1365-182X 1477-2574 Journal FOREIGN 27 3 393 401 393 9 2025 In pancreatic surgery Postoperative pancreatic fistula (POPF) represents the most dreaded complication, for which pancreatic texture is acknowledged as one of the strongest predictors. No consensual objective reference has been defined to evaluate the pancreas composition. The presented study aimed to mine histology data of the pancreatic tissue composition with AI assist and correlate it with clinic-pathological parameters derived from the RECOPANC study.From 320 patients originally included in the RECOPANC multicentric study, after series of exclusions slides of 134 patients were selected of AI-assisted analysis.For each slide tissue training fields were defined. Machine learning was trained to differentiate the tissue compartments: acinar, fibrotic, and adipose tissue, followed by quantification of the tissue area compartments.Relative fibrotic tissue area revealed as the strongest determinant for the prediction of clinically relevant POPF in multivariable analysis (p = 0.027). The AI assessed amount of fibrotic tissue performed significantly better in prediction of fistula development compared to the surgical palpatory assessment of the pancreatic texture.The present study is the first correlating AI-assisted quantified pancreatic tissue composition and POPF within a multicentric cohort. true true INTERNATIONAL 2025 true true true false true false NONE 2026-06-02 false 3 0 3 3 0 3 3 3 2 3 3 3 3 3 0 0 3 3 3 3 0 1 1 Folyóiratcikk Journal Article 24 3 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 2 2 2 2 2026 0 1 1 1 1 Q1 false false false false 2025-01-22T13:26:02.945+0000 Morfológiai és Fiziológiai Tanszék (SE / ETK2007); Országos Onkológiai Intézet; Transzlációs Medicina Intézet (SE / AOK / I) 3 18 3 11 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 122864452 /api/authorship/122864452 1 0.091 true false false Author 10070451 /api/author/10070451 Mályi Ambrus Gábor true true Màlyi Ambrus true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864453 /api/authorship/122864453 2 0.09090909 false false false Bronsert Peter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864454 /api/authorship/122864454 3 0.09090909 false false false Schilling Oliver true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864455 /api/authorship/122864455 4 0.09090909 false false false Honselmann Kim C true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864456 /api/authorship/122864456 5 0.09090909 false false false Bolm Louisa true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864457 /api/authorship/122864457 6 0.091 false false false Author 10055363 /api/author/10055363 Szanyi Szilárd true 10055363 true Szanyi Szilárd true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864458 /api/authorship/122864458 7 0.09090909 false false false Author 10009921 /api/author/10009921 Benyó Zoltán true 10009921 true Benyó Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864459 /api/authorship/122864459 8 0.09090909 false false false Werner Martin true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864460 /api/authorship/122864460 9 0.09090909 false false false Keck Tobias true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864461 /api/authorship/122864461 10 0.09090909 false false false Wellner Ulrich F true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122864462 /api/authorship/122864462 11 0.091 false true true Timme Sylvia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true OrgAuthorship 122864463 /api/authorship/122864463 12 0.0 false false false true false false AuthorshipType 30 /api/authorshiptype/30 -29 true -29 true false true PublicationIdentifier 28255533 /api/publicationidentifier/28255533 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1016/j.hpb.2024.12.012 https://doi.org/10.1016/j.hpb.2024.12.012 false true PublicationIdentifier 28828029 /api/publicationidentifier/28828029 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001437207700001 https://www.webofscience.com/wos/woscc/full-record/001437207700001 true true PublicationIdentifier 28320769 /api/publicationidentifier/28320769 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85215215045 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85215215045 true true PublicationIdentifier 28255532 /api/publicationidentifier/28255532 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 39818518 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=39818518&dopt=Abstract false true SjrRating 11583964 /api/sjrrating/11583964 38 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2715 /api/classificationexternal/2715 true 2715 true Q1 DIRECT true true /api/publication/35701376 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10070451"><a href="/gui2/?type=authors&mode=browse&sel=10070451" target="_blank">Màlyi Ambrus (<span class="authorship-author-name">Mályi Ambrus Gábor</span> <span class="authorAux-mtmt"> Transzlációs patológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Bronsert Peter </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Schilling Oliver </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Honselmann Kim C </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Bolm Louisa </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10055363"><a href="/gui2/?type=authors&mode=browse&sel=10055363" target="_blank">Szanyi Szilárd (<span class="authorship-author-name">Szanyi Szilárd</span> <span class="authorAux-mtmt"> orvostudomány</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Egészségtudományi Kar">ETK2007</span>/Morfológiai és Fiziológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009921"><a href="/gui2/?type=authors&mode=browse&sel=10009921" target="_blank">Benyó Zoltán (<span class="authorship-author-name">Benyó Zoltán</span> <span class="authorAux-mtmt"> Élettan és kórélettan</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Werner Martin </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Keck Tobias </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Wellner Ulrich F </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Timme Sylvia ✉ </span> </div> <div class="autype autype-29"> Kollaborációs szervezet: <span class="author-affil">RECOPANC Study group</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35701376" target="_blank">Postoperative pancreatic fistula risk assessment using digital pathology based analyses at the parenchymal resection margin of the pancreas - Results from the randomized multicenter RECOPANC trial.</a></div> <div> <span class="journal-title">HPB</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1365-182X">1365-182X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1477-2574">1477-2574</a>)</span>: <span class="journal-volume">27</span> <span class="journal-issue">3</span> <span class="page"> pp 393-401 </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1016/j.hpb.2024.12.012" target="_blank" href="https://doi.org/10.1016/j.hpb.2024.12.012"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001437207700001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001437207700001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85215215045" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85215215045"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="39818518" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=39818518&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Gastroenterology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Hepatology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 3</span> | Független: 3 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 3 | Scopus jelölt:&nbsp;2 | WoS/Scopus jelölt:&nbsp;3 | DOI jelölt:&nbsp;3 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;35701376&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 35701376</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Sokszerzős vagy csoportos szerzőségű szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2025.03.14. 11:53 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> 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