https://m2.mtmt.hu/ hun 2026-09-21 13:43 JournalArticle 35676976 VALIDATED true 0 false 2026-07-27T11:15:52.047+0000 2025-10-02T10:46:40.613+0000 2025-01-10T08:31:37.968+0000 true 10015206 Áncsán Gizella /api/admin/10015206 Admin Áncsán Gizella (SE admin) true 10015206 2025-12-28T20:51:48.034+0000 2025-02-06T12:03:54.162+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType Összefoglaló cikk (Folyóiratcikk) 102 true 1134514 true 1 /api/category/1 Category Tudományos true 1 Nazli, Adila true true /api/journal/10022148 REVIEWED PHARMACEUTICS 1999-4923 true false 10022148 false 10022148 true 1999-4923 Journal FOREIGN 17 1 81 81 42 2025 Cyclodextrins can serve as carriers for various payloads, utilizing their capacity to form unique host–guest inclusion complexes within their cavity and their versatile surface functionalization. Recently, cationic cyclodextrins have gained considerable attention, as they can improve drug permeability across negatively charged cell membranes and efficiently condense negatively charged nucleic acid due to electrostatic interactions. This review focuses on state-of-the-art and recent advances in the construction of cationic cyclodextrin-based delivery systems. First, we identified different cationic moieties that are commonly employed in the design of cyclodextrins with enhanced complexation ability. Subsequently, a wide range of cationic cyclodextrin-based drug delivery systems were analyzed with emphasis on chemistry, drug release profiles, and therapeutic outcomes. The evaluation of the delivery platforms was also based on the four major types of drugs, such as anticancer, anti-inflammatory, antibacterial, and antidiabetic agents. The delivery systems for nucleic acids were also summarized while focusing on their condensation ability, transfection efficiency, and biocompatibility in comparison to commercially available vectors such as PEI 25 kDa and lipofectamine 2000. Furthermore, we highlighted the potential of cationic cyclodextrins in constructing multimodal delivery systems for the simultaneous encapsulation of both drugs and nucleic acids. Finally, the challenges and limitations associated with cationic cyclodextrin setups were discussed. Funding 2049431 /api/funding/2049431 (SE250+ Excellence Scholarship for PhD Students) false true true true 2025 true true true false true false GOLD 2026-07-27 true https://doi.org/10.3390/pharmaceutics17010081 14 0 14 11 1 14 14 13 10 14 14 11 11 11 3 0 14 11 14 11 0 6 6 Folyóiratcikk Journal Article 24 14 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 6 5 6 5 2026 0 8 6 8 6 D1 false false false false 2025-01-29T09:34:30.924+0000 Analitikai Kémiai Tanszék (ELTE / TTK / KI); Farmakognóziai Intézet (SE / GYTK) 2 9 2 4 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 122672845 /api/authorship/122672845 Nazli, Adila [Nazli, Adila (farmakognózia), szerző] Farmakognóziai Intézet (SE / GYTK) 1 0.25 true false false Author 10087515 /api/author/10087515 Nazli Adila (farmakognózia) Nazli Adila true true Nazli Adila true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 122672846 /api/authorship/122672846 Malanga, Milo 2 0.25 false false false Malanga Milo true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 122672847 /api/authorship/122672847 Sohajda, Tamás 3 0.25 false false false Sohajda Tamás true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 122672848 /api/authorship/122672848 Béni, Szabolcs ✉ [Béni, Szabolcs (NMR-spektroszkópi...), szerző] Analitikai Kémiai Tanszék (ELTE / TTK / KI) 4 0.25 false true true Author 10001293 /api/author/10001293 Béni Szabolcs (NMR-spektroszkópia, analitikai kémia) Béni Szabolcs true 10001293 true Béni Szabolcs true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 28189857 /api/publicationidentifier/28189857 DOI: 10.3390/pharmaceutics17010081 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/pharmaceutics17010081 https://doi.org/10.3390/pharmaceutics17010081 false true PublicationIdentifier 28356519 /api/publicationidentifier/28356519 WoS: 001403833000001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001403833000001 https://www.webofscience.com/wos/woscc/full-record/001403833000001 true true PublicationIdentifier 29936503 /api/publicationidentifier/29936503 EDIT: 118140 SwordSource 92 /api/publicationsource/92 EDIT PublicationSourceType 10007 /api/publicationsourcetype/10007 Repozitórium true true true EDIT EDIT https://edit.elte.hu/xmlui/handle/10831/@@@ true true 92 true GREEN true IDENTICAL 118140 https://edit.elte.hu/xmlui/handle/10831/118140 false true PublicationIdentifier 28314585 /api/publicationidentifier/28314585 Scopus: 85215797940 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85215797940 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85215797940 false true PublicationIdentifier 28356522 /api/publicationidentifier/28356522 PubMed: 39861729 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 39861729 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=39861729&dopt=Abstract true true Classification 12184 /api/classification/12184 Farmakológia és gyógyszerészet true true SjrRating 11611771 /api/sjrrating/11611771 sjr:D1 (2025) Scopus - Pharmaceutical Science PHARMACEUTICS 1999-4923 18 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 3003 /api/classificationexternal/3003 Scopus - Pharmaceutical Science true 3003 true D1 DIRECT true true Reference 61488900 /api/reference/61488900 1. 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(2025) PHARMACEUTICS 1999-4923 17 1<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10087515"><a href="/gui2/?type=authors&mode=browse&sel=10087515" target="_blank">Nazli Adila (<span class="authorship-author-name">Nazli Adila</span> <span class="authorAux-mtmt"> farmakognózia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Farmakognóziai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Malanga Milo </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sohajda Tamás </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001293"><a href="/gui2/?type=authors&mode=browse&sel=10001293" target="_blank">Béni Szabolcs ✉ (<span class="authorship-author-name">Béni Szabolcs</span> <span class="authorAux-mtmt"> NMR-spektroszkópia, analitikai kémia</span>) </a> </span> <span class="author-affil"><span title="Eötvös Loránd Tudományegyetem">ELTE</span>/<span title="Természettudományi Kar">TTK</span>/<span title="Kémiai Intézet">KI</span>/Analitikai Kémiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35676976" target="_blank">Cationic Cyclodextrin-Based Carriers for Drug and Nucleic Acid Delivery</a></div> <div> <span class="journal-title">PHARMACEUTICS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/1999-4923">1999-4923</a>)</span>: <span class="journal-volume">17</span> <span class="journal-issue">1</span> <span class="page"> Paper 81. 42 p. </span> <span class="year">(2025)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/pharmaceutics17010081" target="_blank" href="https://doi.org/10.3390/pharmaceutics17010081"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001403833000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001403833000001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="118140" target="_blank" href="https://edit.elte.hu/xmlui/handle/10831/118140"> EDIT </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85215797940" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85215797940"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="39861729" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=39861729&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmaceutical Science&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 14</span> | Független: 11 | Függő: 3 | Nem jelölt: 0 | WoS jelölt: 13 | Scopus jelölt:&nbsp;10 | WoS/Scopus jelölt:&nbsp;14 | DOI jelölt:&nbsp;14 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;35676976&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 6 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 35676976</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (SE250+ Excellence Scholarship for PhD Students) </div> <div class="lastModified">Utolsó módosítás: 2025.10.02. 12:46 Csámer Iván (ELTE TTK kari admin 5) </div> </div></div>