https://m2.mtmt.hu/ hun 2026-10-24 05:21 JournalArticle 35639981 VALIDATED true Department of Pulmonology, Semmelweis University Clinical Center, Budapest, Hungary Department of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary Institute of Digital Health Sciences, Semmelweis University, Budapest, Hungary Export Date: 28 January 2025 Correspondence Address: Csósza, G.; Department of Pulmonology, 25-29 Tömő Str., Hungary; email: csosza.gyorgyi@semmelweis.hu Chemicals/CAS: alanine aminotransferase, 9000-86-6, 9014-30-6; aspartate aminotransferase, 9000-97-9; gamma glutamyltransferase, 85876-02-4 Tradenames: Cobas b 221, Hoffmann La Roche; Corodyn, B Braun SE; Mindray DC-70 X-Insight, Shenzhen Mindray Bio-Medical Electronics Manufacturers: B Braun SE; Hoffmann La Roche; Shenzhen Mindray Bio-Medical Electronics 0 false 2026-10-04T08:25:14.413+0000 2024-12-31T07:44:54.915+0000 2024-12-16T12:55:06.789+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 2025-01-28T12:03:28.707+0000 2024-12-31T07:44:54.921+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Csósza, Györgyi Right ventricular stroke work index in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: A retrospective observational study true true /api/journal/10050313 REVIEWED true false 10050313 false 10050313 true 2045-8932 2045-8940 Journal FOREIGN 14 4 e12433 e12433 11 2024 The right ventricular stroke work index (RVSWI) reflects the active work of the right ventricle (RV), but its clinical usefulness is not yet fully known in pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). We aimed to evaluate the correlation of RVSWI to clinical parameters, the presence of comorbidities and response to therapy. We performed a retrospective observational study of 54 patients (PAH: N = 30, CTEPH: N = 24) and control patients ( N = 11), and collected clinical data including RVSWI and comorbidities at baseline. We also compared changes in the parameters of the four‐strata mortality risk score at follow‐up (median time of 12 months) after the initiation of therapy between patients with low‐ (<1450 mmHg*mL/m 2 , N = 18) and high‐RVSWI values (≥1450 mmHg*mL/m 2 , N = 19). RVSWI at diagnosis was higher in PAH/CTEPH compared to control subjects (1408 ± 391 vs. 704 ± 140 mmHg*mL/m 2 , p < 0.001, mean ± standard deviation, t ‐test), but did not differ between PAH and CTEPH patients (1406 ± 342 vs. 1409 ± 470 mmHg*mL/m 2 , p = 0.98). Patients without comorbidities had higher RVSWI than those with comorbidities ( N = 23: 1522 ± 400 vs. N = 31: 1323 ± 384 mmHg*mL/m 2 , p = 0.04), which was also found in PAH ( p < 0.001), but not in CTEPH ( p = 0.37). A greater improvement in the four‐strata mortality risk score ( p < 0.05) and a trend for a larger reduction in N‐terminal proB‐type natriuretic peptide concentration ( p = 0.06) were observed in the high‐RVSWI subgroup than in the low‐RVSWI patients at follow‐up. In PAH and CTEPH, RVSWI provides additional information on RV function in comorbidities, and it may predict response to specific therapy. Regular monitoring of RVSWI may aid in optimizing therapy selection and timing. true true 2024 true true true false true false GOLD 2026-10-04 true https://doi.org/10.1002/pul2.12433 6 0 6 5 1 6 6 4 6 6 6 5 5 5 1 0 6 5 6 5 0 1 1 Folyóiratcikk Journal Article 24 6 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 0 1 0 2026 0 5 5 5 5 Q2 false false false false 2024-12-15T12:55:12.496+0000 Aneszteziológiai és Intenzív Terápiás Tanszék (SE / AOK / K); Digitális Egészségtudományi Intézet (SE / EKK); Pulmonológiai Klinika (SE / AOK / K) 7 22 3 7 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 122204727 /api/authorship/122204727 1 0.143 true false true Author 10024052 /api/author/10024052 Csósza Györgyi true 10024052 true Csósza Györgyi true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122204728 /api/authorship/122204728 2 0.143 false false false Author 10027062 /api/author/10027062 Valkó Luca true 10027062 true Valkó Luca true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122204729 /api/authorship/122204729 3 0.143 false false false Author 10009579 /api/author/10009579 Dinya Elek true 10009579 true Dinya Elek true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 122204730 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class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10024052"><a href="/gui2/?type=authors&mode=browse&sel=10024052" target="_blank">Csósza Györgyi ✉ (<span class="authorship-author-name">Csósza Györgyi</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pulmonológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10027062"><a href="/gui2/?type=authors&mode=browse&sel=10027062" target="_blank">Valkó Luca (<span class="authorship-author-name">Valkó Luca</span> <span class="authorAux-mtmt"> Aneszteziológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Aneszteziológiai és Intenzív Terápiás Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009579"><a href="/gui2/?type=authors&mode=browse&sel=10009579" target="_blank">Dinya Elek (<span class="authorship-author-name">Dinya Elek</span> <span class="authorAux-mtmt"> Orvosi biometria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Egészségügyi Közszolgálati Kar">EKK</span>/Digitális Egészségtudományi Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10004124"><a href="/gui2/?type=authors&mode=browse&sel=10004124" target="_blank">Losonczy György (<span class="authorship-author-name">Losonczy György</span> <span class="authorAux-mtmt"> Pulmonológia, klinikai onkológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pulmonológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012282"><a href="/gui2/?type=authors&mode=browse&sel=10012282" target="_blank">Müller Veronika (<span class="authorship-author-name">Müller Veronika</span> <span class="authorAux-mtmt"> Pulmonológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pulmonológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10026588"><a href="/gui2/?type=authors&mode=browse&sel=10026588" target="_blank">Lázár Zsófia<sup>**</sup> (<span class="authorship-author-name">Lázár Zsófia</span> <span class="authorAux-mtmt"> Pulmonológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pulmonológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024026"><a href="/gui2/?type=authors&mode=browse&sel=10024026" target="_blank">Karlócai Kristóf (<span class="authorship-author-name">Karlócai Kristóf</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pulmonológiai Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35639981" target="_blank">Right ventricular stroke work index in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: A retrospective observational study</a></div> <div> <span class="journal-title">PULMONARY CIRCULATION</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2045-8932">2045-8932</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2045-8940">2045-8940</a>)</span>: <span class="journal-volume">14</span> <span class="journal-issue">4</span> <span class="page"> Paper e12433. 11 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1002/pul2.12433" target="_blank" href="https://doi.org/10.1002/pul2.12433"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001377543300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001377543300001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85212088430" target="_blank" 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href="/api/publication?cond=citations.related;eq;35639981&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 35639981</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2024.12.31. 08:44 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Pulmonology, Semmelweis University Clinical Center, Budapest, Hungary Department of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary Institute of Digital Health Sciences, Semmelweis University, Budapest, Hungary Export Date: 28 January 2025 Correspondence A...</pre> </div></div>