https://m2.mtmt.hu/ hun 2026-05-30 18:03 JournalArticle 35508435 VALIDATED true 0 false 2026-05-29T22:18:15.924+0000 2024-12-16T14:52:09.403+0000 2024-11-07T18:07:04.306+0000 true 10037971 Nagy-Grócz Gábor /api/author/10037971 Author true 10037971 2025-09-27T16:04:48.647+0000 2024-12-16T14:52:09.685+0000 true 10082734 Bajtai Anikó /api/admin/10082734 Admin true Admin 10025544 /api/admin/10025544 Lévayné Deseő Katalin true 10025544 true 2025-06-04T22:07:20.889+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Kis-György, Rita The Connection Between the Oral Microbiota and the Kynurenine Pathway: Insights into Oral and Certain Systemic Disorders true true /api/journal/10005621 REVIEWED true false 10005621 false 10005621 true 1467-3037 1467-3045 Journal FOREIGN 46 11 12641 12657 12641 17 2024 The oral microbiome, comprising bacteria, fungi, viruses, and protozoa, is essential for maintaining both oral and systemic health. This complex ecosystem includes over 700 bacterial species, such as Streptococcus mutans, which contributes to dental caries through acid production that demineralizes tooth enamel. Fungi like Candida and pathogens such as Porphyromonas gingivalis are also significant, as they can lead to periodontal diseases through inflammation and destruction of tooth-supporting structures. Dysbiosis, or microbial imbalance, is a key factor in the development of these oral diseases. Understanding the composition and functions of the oral microbiome is vital for creating targeted therapies for these conditions. Additionally, the kynurenine pathway, which processes the amino acid tryptophan, plays a crucial role in immune regulation, neuroprotection, and inflammation. Oral bacteria can metabolize tryptophan, influencing the production of kynurenine, kynurenic acid, and quinolinic acid, thereby affecting the kynurenine system. The balance of microbial species in the oral cavity can impact tryptophan levels and its metabolites. This narrative review aims to explore the relationship between the oral microbiome, oral diseases, and the kynurenine system in relation to certain systemic diseases. true true 2024 true true true false true false GOLD 2026-05-30 true https://doi.org/10.3390/cimb46110750 12 3 12 11 1 12 12 7 4 7 7 6 6 11 1 0 12 11 12 11 0 11 11 Folyóiratcikk Journal Article 24 12 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 5 5 5 5 2026 0 7 6 7 6 Q2 false 10037971 false false false 2024-11-12T08:10:26.655+0000 Egészségmagatartás és -fejlesztés Szakcsoport (SZTE / ETSZK); Egészségtudományi és Egészségügyi Menedzsment T... (SZTE / ETSZK); HUN-REN-SZTE Idegtudományi Kutatócsoport (SZTE / SZAOK / NeurK); Interdiszciplináris Orvostudományok Doktori Iskola (SZTE / DI); Szülészeti és Nőgyógyászati Klinika Üllői úti r... 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131 10.1016/j.cmet.2023.06.004 false true /api/publication/35508435 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10095941"><a href="/gui2/?type=authors&mode=browse&sel=10095941" target="_blank">Kis-György Rita (<span class="authorship-author-name">Kis-György Rita</span> <span class="authorAux-mtmt"> Dentálhigiénia, Epidemiológia</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Egészségtudományi és Szociális Képzési Kar">ETSZK</span>/Egészségmagatartás és -fejlesztés Szakcsoport; <span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Doktori Iskolák">DI</span>/Interdiszciplináris Orvostudományok Doktori Iskola</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10054607"><a href="/gui2/?type=authors&mode=browse&sel=10054607" target="_blank">Körtési Tamás (<span class="authorship-author-name">Körtési Tamás</span> <span class="authorAux-mtmt"> Neurobiológia</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Egészségtudományi és Szociális Képzési Kar">ETSZK</span>/Egészségtudományi és Egészségügyi Menedzsment Tanszék; <span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Szent-Györgyi Albert Orvostudományi Kar">SZAOK</span>/<span title="Neurológiai Klinika">NeurK</span>/HUN-REN-SZTE Idegtudományi Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10098327"><a href="/gui2/?type=authors&mode=browse&sel=10098327" target="_blank">Anicka Alexandra (<span class="authorship-author-name">Anicka Alexandra</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Szülészeti és Nőgyógyászati Klinika">SZSZNK</span>/Szülészeti és Nőgyógyászati Klinika Üllői úti részleg</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037971"><a href="/gui2/?type=authors&mode=browse&sel=10037971" target="_blank">Nagy-Grócz Gábor ✉ (<span class="authorship-author-name">Nagy-Grócz Gábor</span> <span class="authorAux-mtmt"> Idegtudományok, Egészségtudományok</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Egészségtudományi és Szociális Képzési Kar">ETSZK</span>/Egészségtudományi és Egészségügyi Menedzsment Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35508435" target="_blank">The Connection Between the Oral Microbiota and the Kynurenine Pathway: Insights into Oral and Certain Systemic Disorders</a></div> <div> <span class="journal-title">CURRENT ISSUES IN MOLECULAR BIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1467-3037">1467-3037</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1467-3045">1467-3045</a>)</span>: <span class="journal-volume">46</span> <span class="journal-issue">11</span> <span class="page"> pp 12641-12657 </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/cimb46110750" target="_blank" href="https://doi.org/10.3390/cimb46110750"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001364080800001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001364080800001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85210452302" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85210452302"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="39590344" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=39590344&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="35141" target="_blank" href="http://publicatio.bibl.u-szeged.hu/35141"> SZTE Publicatio </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Microbiology (medical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Microbiology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Molecular Biology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 12</span> | Független: 11 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 7 | Scopus jelölt:&nbsp;4 | WoS/Scopus jelölt:&nbsp;7 | DOI jelölt:&nbsp;12 (Nem nyilvános:&nbsp;3) </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;35508435&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 11 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 35508435</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2024.12.16. 15:52 Bajtai Anikó (SZTE admin5) </div> <div class="lockedBy">Központi kezelésű 2025.06.05. 00:07 Lévayné Deseő Katalin (MTMT Központi admin) </div> </div></div>