Background In the evolving healthcare landscape of the United Arab Emirates (UAE),
establishing cost-effectiveness thresholds (CETs) is pivotal to informing decision-makers
about the value of health technologies.Objective This study aimed to establish CETs
for the UAE that harmonise with international standards while reflecting the nation’s
unique healthcare needs and economic context.Setting United Arab Emirates.Methods
A multitiered methodology was employed, involving a literature review, a panel of
national experts and workshops with key stakeholders, including healthcare providers,
government health departments and healthcare payers. The panel and workshops were
integral in assessing global CET practices and their applicability to the UAE providing
a preliminary framework for CET in the UAE. Structured voting sessions were then conducted
allowing voting on crucial aspects of CET to determine the baseline threshold, multipliers
for severity, rarity and health gain, and methodologies for quantifying disease severity.Results
CETs were linked to the economic status of the UAE, with a baseline threshold of 0.75
times the gross domestic product per capita for one quality-adjusted life year gained.
A multiplier system was introduced to reflect societal views on disease severity,
disease rarity and the relative health benefit of health technologies. Based on the
voting results, disease rarity was deemed the most crucial factor, receiving a maximum
multiplier of 3X, while severity and health gain were assigned a maximum of 2X. The
multiplier values for both disease severity and relative health gain would be determined
on a continuous scale. The proportional or relative shortfall method would be used
to assess disease severity.Conclusions The proposed CET framework for the UAE will
be dependent on local generation of cost-effectiveness evidence. Periodic review of
CETs based on initial experiences ensures the responsiveness of policymakers to the
changing healthcare and economic environment.All data relevant to the study are included
in the article or uploaded as supplementary information.
