https://m2.mtmt.hu/ eng 2026-05-30 22:43 JournalArticle 35179536 VALIDATED true Funding text: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. 0 false 2026-05-24T02:21:22.757+0000 2025-07-08T11:52:26.451+0000 2024-08-23T07:21:36.296+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 2025-04-01T04:59:20.708+0000 2024-12-06T18:09:56.370+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Szondy, I Doxycycline prophylaxis for the prevention of sexually transmitted infections : a systematic review and meta-analysis of randomised controlled trials true true /api/journal/10005672 REVIEWED true false 10005672 false 10005672 true 1201-9712 1878-3511 Journal FOREIGN 147 107186 107186 11 2024 To investigate the effects of doxycycline pre- and post-exposure prophylaxis (doxy-PrEP/PEP) on bacterial sexually transmitted infections (STIs) by conducting a systematic review and meta-analysis.PubMed, Embase, and CENTRAL were searched for randomised controlled trials (RCTs), including ongoing studies published until 7 November 2023. Our primary endpoint was the incidence of bacterial STIs measured as the number of visits with an STI per total number of visits. Random-effects model was used to estimate pooled effect sizes. The study was registered with PROSPERO, CRD42023478486.We identified six eligible studies containing data from seven articles and four conference abstracts, enrolling men who have sex with men (MSM), transgender women (TGW) and cisgender women (CGW). The pooled analysis of 1,766 participants with 602 newly diagnosed STIs showed a 56% decrease in the overall STI incidence using doxy-PrEP/PEP (RR=0.44; 95%CI: 0.30-0.65; I2=73%). For doxy-PEP, including MSM and TGW only, the RR observed for overall STI incidence was 0.40 (95%CI: 0.28-0.57; I²=37%), 0.19 (95%CI: 0.08-0.44; I²=39%) for chlamydia, 0.23 (0.14-0.36; I²=0%) for syphilis and 0.55 (95%CI: 0.34-0.87; I²=41%) for gonorrhoea. No serious adverse were reported in the studies. The certainty of evidence regarding the efficacy of doxy-PEP among MSM and TGW was graded as high.Doxy-PEP significantly reduces the number of new cases of chlamydia and syphilis and is potentially effective against gonorrhoea, influenced by local resistance patterns. Thus, it is a promising tool in the prevention of bacterial STIs among MSM and TGW. true true 2024 true true true false true false GOLD 2026-05-24 true https://doi.org/10.1016/j.ijid.2024.107186 30 0 30 28 1 30 30 29 17 30 30 28 28 28 2 0 30 28 30 28 0 2 2 Folyóiratcikk Journal Article 24 30 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 2 2 2 2 2025 0 22 20 22 20 2026 0 6 6 6 6 Q1 false 10037621,10079444 false false false 2024-09-16T09:24:28.591+0000 Bőr-, Nemikórtani és Bőronkológiai Klinika (SE / AOK / K); HCEMM-SE Transzlációs Dermatológiai Kutatócsoport (SE / AOK / K / BNBK); Pankreász Betegségek Intézete (SE / AOK / K); Transzlációs Medicina Intézet (PTE / ÁOK); Transzlációs Medicina Központ (SE / KSZE); Élettani Intézet (SE / AOK / I) 8 44 6 9 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 118656680 /api/authorship/118656680 1 0.111 true false false Author 10089672 /api/author/10089672 Szondy István true true Szondy I true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118656681 /api/authorship/118656681 2 0.111 false false false Author 10079444 /api/author/10079444 Meznerics Fanni Adél true true Meznerics F A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118656682 /api/authorship/118656682 3 0.111 false false false Author 10038409 /api/author/10038409 Lőrincz Kende Kálmán true 10038409 true Lőrincz K true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118656683 /api/authorship/118656683 4 0.111 false false false Author 10040817 /api/author/10040817 Kemény Lajos Vince true 10040817 true Kemény L V true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118656684 /api/authorship/118656684 5 0.11111111 false false false Walter A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118656685 /api/authorship/118656685 6 0.11111111 false false false Author 10100258 /api/author/10100258 Mohammed Alzahra Ahmed true true Mohammed A A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118656686 /api/authorship/118656686 7 0.111 false false false Author 10002629 /api/author/10002629 Hegyi Péter true 10002629 true Hegyi P true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118656687 /api/authorship/118656687 8 0.111 false false false Author 10054754 /api/author/10054754 Kiss Norbert true 10054754 true Kiss N true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118656688 /api/authorship/118656688 9 0.111 false true true Author 10037621 /api/author/10037621 Bánvölgyi András true 10037621 true Bánvölgyi A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 26950608 /api/publicationidentifier/26950608 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1016/j.ijid.2024.107186 https://doi.org/10.1016/j.ijid.2024.107186 false true PublicationIdentifier 27533695 /api/publicationidentifier/27533695 PlainSource 1 /api/publicationsource/1 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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=39122208&dopt=Abstract false true Keyword 3375201 /api/keyword/3375201 true true SjrRating 11473240 /api/sjrrating/11473240 42 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2725 /api/classificationexternal/2725 true 2725 true Q1 DIRECT true true /api/publication/35179536 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10089672"><a href="/gui2/?type=authors&mode=browse&sel=10089672" target="_blank">Szondy I (<span class="authorship-author-name">Szondy István</span> <span class="authorAux-mtmt"> Hidradenitis suppurativa korszerű kezelése</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10079444"><a href="/gui2/?type=authors&mode=browse&sel=10079444" target="_blank">Meznerics F A (<span class="authorship-author-name">Meznerics Fanni Adél</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10038409"><a href="/gui2/?type=authors&mode=browse&sel=10038409" target="_blank">Lőrincz K (<span class="authorship-author-name">Lőrincz Kende Kálmán</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10040817"><a href="/gui2/?type=authors&mode=browse&sel=10040817" target="_blank">Kemény L V (<span class="authorship-author-name">Kemény Lajos Vince</span> <span class="authorAux-mtmt"> Bőrgyógyászat, onkológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Physiology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Dermatology, Dermatooncology and Venerology">DDDV</span>/HCEMM-SU Translational Dermatology Research Group; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Walter A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10100258"><a href="/gui2/?type=authors&mode=browse&sel=10100258" target="_blank">Mohammed A A (<span class="authorship-author-name">Mohammed Alzahra Ahmed</span> <span class="authorAux-mtmt"> Dermatology</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002629"><a href="/gui2/?type=authors&mode=browse&sel=10002629" target="_blank">Hegyi P (<span class="authorship-author-name">Hegyi Péter</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Institute for Translational Medicine; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Institute of Pancreatic Diseases; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10054754"><a href="/gui2/?type=authors&mode=browse&sel=10054754" target="_blank">Kiss N (<span class="authorship-author-name">Kiss Norbert</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037621"><a href="/gui2/?type=authors&mode=browse&sel=10037621" target="_blank">Bánvölgyi A ✉ (<span class="authorship-author-name">Bánvölgyi András</span> <span class="authorAux-mtmt"> bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Dermatology, Dermatooncology and Venerology; <span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Centre for Translational Medicine</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35179536" target="_blank">Doxycycline prophylaxis for the prevention of sexually transmitted infections : a systematic review and meta-analysis of randomised controlled trials</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1201-9712">1201-9712</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1878-3511">1878-3511</a>)</span>: <span class="journal-volume">147</span> <span class="page"> Paper 107186. 11 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1016/j.ijid.2024.107186" target="_blank" href="https://doi.org/10.1016/j.ijid.2024.107186"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001313126200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001313126200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85203283672" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85203283672"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="39122208" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=39122208&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Infectious Diseases&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Microbiology (medical)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 30</span> | Independent citation: 28 | Self citation: 2 | Unknown citation: 0 | Number of citations in WoS: 29 | Number of citations in Scopus:&nbsp;17 | WoS/Scopus assigned:&nbsp;30 | Number of citations with DOI:&nbsp;30 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;35179536&sort=publishedYear,desc&sort=title"> Number of cited publications: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 35179536</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">PubMed XML</span> </div> <div class="lastModified">Last Modified: 2025.07.08. 13:52 Tamásné Gere (SE_KK_Admin5_GT, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Funding text: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</pre> </div></div>