Natural products (NPs) have long been used as a rich source of bioactive compounds
for drug development. Recent technological advancements have revitalised natural products
research as evidenced by increased publications in this field. In this editorial review,
we highlight key points from the 2020 British Journal of Pharmacology (BJP) practical
guide, which outlines standards for natural products research reports, and provide
papers published in BJP between years 2020 to 2023 that demonstrate adherence to these
guidelines. Looking ahead, we discuss the potential of chemical proteomics approaches
to elucidate natural products mechanisms of action and identify therapeutic targets
for future research. By fostering innovation, we aim to advance natural products research
and contribute to the development of novel therapeutics that will have a significant
impact on healthcare.