https://m2.mtmt.hu/ hun 2026-09-20 16:05 JournalArticle 35156513 VALIDATED true Funding text: The authors wish to thank Siposne Radvanyi Zsuzsa, for performing part of the prenatal ultrasound examinations. The authors are also thankful to Kutasi Aniko and Glovocz Bea, for their valuable technical help. 0 false 2026-07-31T14:51:01.745+0000 2026-02-04T11:03:26.671+0000 2024-08-02T06:35:54.929+0000 true 10000568 Beke Artúr /api/author/10000568 Author Beke Artúr (Genetika, Szülészeti genetika, Szülészet-Nőgyógyászat) true 10000568 2026-02-04T11:03:27.032+0000 2026-02-04T11:03:27.032+0000 2024-08-07T07:32:59.670+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin Molnár-Taga Márta (SE 4-es admin) true 10062250 Admin 10073918 /api/admin/10073918 Kovács Marcell (MTMT Közp., admin) Kovács Marcell true true 2026-01-26T16:13:41.604+0000 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Bartek, Virág true true /api/journal/10071196 REVIEWED CHILDREN (BASEL) 2227-9067 true false 10071196 false 10071196 true 2227-9067 Journal FOREIGN 11 7 797 797 14 2024 Introduction: The corpus callosum is one of the five main cerebral commissures. It is key to combining sensory and motor functions. Its structure can be pathological (dysgenesis) or completely absent (agenesis). The corpus callosum dys- or agenesis is a rare disease (1:4000 live births), but it can have serious mental effects. Methods: In our study, we processed the data of 64 pregnant women. They attended a prenatal diagnostic center and genetic counseling from 2005 to 2019 at the Department of Obstetrics and Gynecology at Semmelweis University. Results: The pregnancies had the following outcomes: 52 ended in delivery, 1 in spontaneous abortion, and 11 in termination of pregnancy (TOP) cases (n = 64). The average time of detection with imaging tests was 25.24 gestational weeks. In 16 cases, prenatal magnetic resonance imaging (MRI) was performed. If the abnormality was detected before the 20th week, a genetic test was performed on an amniotic fluid sample obtained from a genetic amniocentesis. Karyotyping and cytogenetic tests were performed in 15 of the investigated cases. Karyotyping gave normal results in three cases (46,XX or XY). In one of these cases, postnatally chromosomal microarray (CMA) was later performed, which confirmed Aicardi syndrome (3q21.3–21.1 microdeletion). In one case, postnatally, the test found Wiedemann–Rautenstrauch syndrome. In other cases, it found X ring, Di George syndrome, 46,XY,del(13q)(q13q22) and 46,XX,del(5p)(p13) (Cri-du-chat syndrome). Edwards syndrome was diagnosed in six cases, and Patau syndrome in one case. Conclusions: We found that corpus callosum abnormalities are often linked to chromosomal problems. We recommend that a cytogenetic test be performed in all cases to rule out inherited diseases. Also, the long-term outcome does not just depend on the disease’s severity and the associated other conditions, and hence proper follow-up and early development are also key. For this reason, close teamwork between neonatology, developmental neurology, and pediatric surgery is vital. true true 2024 true true true false true false GOLD 2026-07-31 true https://doi.org/10.3390/children11070797 5 0 5 5 0 5 5 5 5 5 5 5 5 5 0 0 5 5 5 5 0 1 1 Folyóiratcikk Journal Article 24 5 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 5 5 5 5 Q2 false false false false 2024-08-06T07:32:59.433+0000 Patológiai és Kísérleti Rákkutató Intézet (SE / AOK / I); Szülészeti és Nőgyógyászati Klinika (SE / AOK / K); Szülészeti és Nőgyógyászati Klinika Üllői úti r... (SE / AOK / K / SZSZNK) 5 29 3 8 0 true 10073918 Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 118481081 /api/authorship/118481081 Bartek, Virág [Bartek, Virág (Orvostudomány), szerző] Szülészeti és Nőgyógyászati Klinika (SE / AOK / K) 1 0.125 true false false Author 10096265 /api/author/10096265 Bartek Virág (Orvostudomány) Bartek Virág true true Bartek Virág true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 118481082 /api/authorship/118481082 Szabó, István 2 0.125 false false false Szabó István true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 118481083 /api/authorship/118481083 Harmath, Ágnes [Harmath, Ágnes (sebészet, csecsem...), szerző] Szülészeti és Nőgyógyászati Klinika (SE / AOK / K) 3 0.125 false false false Author 10020799 /api/author/10020799 Harmath Ágnes (sebészet, csecsemő- és gyermekgyógyászat és neonatológia) Harmath Ágnes true 10020799 true Harmath Ágnes true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 118481084 /api/authorship/118481084 Rudas, Gábor 4 0.125 false false false Rudas Gábor true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 118481085 /api/authorship/118481085 Steiner, Tidhar 5 0.125 false false false Steiner Tidhar true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 118481086 /api/authorship/118481086 Fintha, Attila [Fintha, Attila (patológia), szerző] Patológiai és Kísérleti Rákkutató Intézet (SE / AOK / I) 6 0.125 false false false Author 10026799 /api/author/10026799 Fintha Attila (patológia) Fintha Attila true 10026799 true Fintha Attila true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 118481087 /api/authorship/118481087 Ács, Nándor [Ács, Nándor (Szülészet-nőgyógy...), szerző] Szülészeti és Nőgyógyászati Klinika Üllői úti r... 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(2024) CHILDREN (BASEL) 2227-9067 11 7<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10096265"><a href="/gui2/?type=authors&mode=browse&sel=10096265" target="_blank">Bartek Virág (<span class="authorship-author-name">Bartek Virág</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szülészeti és Nőgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szabó István </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10020799"><a href="/gui2/?type=authors&mode=browse&sel=10020799" target="_blank">Harmath Ágnes (<span class="authorship-author-name">Harmath Ágnes</span> <span class="authorAux-mtmt"> sebészet, csecsemő- és gyermekgyógyászat és neo...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szülészeti és Nőgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Rudas Gábor </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Steiner Tidhar </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10026799"><a href="/gui2/?type=authors&mode=browse&sel=10026799" target="_blank">Fintha Attila (<span class="authorship-author-name">Fintha Attila</span> <span class="authorAux-mtmt"> patológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Patológiai és Kísérleti Rákkutató Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013998"><a href="/gui2/?type=authors&mode=browse&sel=10013998" target="_blank">Ács Nándor (<span class="authorship-author-name">Ács Nándor</span> <span class="authorAux-mtmt"> Szülészet-nőgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Szülészeti és Nőgyógyászati Klinika">SZSZNK</span>/Szülészeti és Nőgyógyászati Klinika Üllői úti részleg</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000568"><a href="/gui2/?type=authors&mode=browse&sel=10000568" target="_blank">Beke Artúr ✉ (<span class="authorship-author-name">Beke Artúr</span> <span class="authorAux-mtmt"> Genetika, Szülészeti genetika, Szülészet-Nőgyóg...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Szülészeti és Nőgyógyászati Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35156513" target="_blank">Prenatal and Postnatal Diagnosis and Genetic Background of Corpus Callosum Malformations and Neonatal Follow-Up</a></div> <div> <span class="journal-title">CHILDREN (BASEL)</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2227-9067">2227-9067</a>)</span>: <span class="journal-volume">11</span> <span class="journal-issue">7</span> <span class="page"> Paper 797. 14 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/children11070797" target="_blank" href="https://doi.org/10.3390/children11070797"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001276481000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001276481000001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="381991340" target="_blank" href="https://www.researchgate.net/publication/381991340"> ResearchGate publ. </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85199622504" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85199622504"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="39062246" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=39062246&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pediatrics, Perinatology and Child Health&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 5</span> | Független: 5 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 5 | Scopus jelölt:&nbsp;5 | WoS/Scopus jelölt:&nbsp;5 | DOI jelölt:&nbsp;5 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;35156513&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 35156513</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2026.02.04. 12:03 Kovács Marcell (MTMT Közp., admin) </div> <div class="lockedBy">Központi kezelésű 2026.01.26. 17:13 Kovács Marcell (MTMT Közp., admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding text: The authors wish to thank Siposne Radvanyi Zsuzsa, for performing part of the prenatal ultrasound examinations. The authors are also thankful to Kutasi Aniko and Glovocz Bea, for their valuable technical help.</pre> </div></div>