https://m2.mtmt.hu/ hun 2026-09-22 11:08 JournalArticle 35067177 VALIDATED true 0 false 2026-07-17T08:49:38.590+0000 2024-06-24T08:00:15.426+0000 2024-06-24T07:26:47.494+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2026-07-17T08:46:58.384+0000 2024-06-24T08:00:15.436+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Ascsillan, Anna A. The Skin-Brain Axis: From UV and Pigmentation to Behaviour Modulation true true /api/journal/10003252 REVIEWED true false 10003252 false 10003252 true 1661-6596 1422-0067 Journal FOREIGN 25 11 6199 6199 19 2024 The skin-brain axis has been suggested to play a role in several pathophysiological conditions, including opioid addiction, Parkinson's disease and many others. Recent evidence suggests that pathways regulating skin pigmentation may directly and indirectly regulate behaviour. Conversely, CNS-driven neural and hormonal responses have been demonstrated to regulate pigmentation, e.g., under stress. Additionally, due to the shared neuroectodermal origins of the melanocytes and neurons in the CNS, certain CNS diseases may be linked to pigmentation-related changes due to common regulators, e.g., MC1R variations. Furthermore, the HPA analogue of the skin connects skin pigmentation to the endocrine system, thereby allowing the skin to index possible hormonal abnormalities visibly. In this review, insight is provided into skin pigment production and neuromelanin synthesis in the brain and recent findings are summarised on how signalling pathways in the skin, with a particular focus on pigmentation, are interconnected with the central nervous system. Thus, this review may supply a better understanding of the mechanism of several skin-brain associations in health and disease. true 2024 true true true false true false GOLD 2026-07-17 false http://www.mdpi.com/journal/ijms 16 0 16 16 0 16 16 16 13 16 16 16 16 16 0 0 16 16 16 16 0 4 4 Folyóiratcikk Journal Article 24 16 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 3 3 3 3 2025 0 8 8 8 8 2026 0 5 5 5 5 D1 false false false false 2024-06-23T08:00:15.246+0000 Bőr-, Nemikórtani és Bőronkológiai Klinika (SE / AOK / K); HCEMM-SE Transzlációs Dermatológiai Kutatócsoport (SE / AOK / K / BNBK); Élettani Intézet (SE / AOK / I) 2 18 3 2 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 118017045 /api/authorship/118017045 1 0.5 true false false Author 10095738 /api/author/10095738 Ascsillán Anna true true Ascsillan Anna A. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 118017046 /api/authorship/118017046 2 0.5 false true true Author 10040817 /api/author/10040817 Kemény Lajos Vince true 10040817 true Kemeny Lajos V. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 26717484 /api/publicationidentifier/26717484 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.3390/ijms25116199 https://doi.org/10.3390/ijms25116199 false true PublicationIdentifier 26717485 /api/publicationidentifier/26717485 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001245702400001 https://www.webofscience.com/wos/woscc/full-record/001245702400001 false true PublicationIdentifier 26717487 /api/publicationidentifier/26717487 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85195851890 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85195851890 false true PublicationIdentifier 26717486 /api/publicationidentifier/26717486 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38892387 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38892387&dopt=Abstract false true Keyword 354 /api/keyword/354 true 354 true Keyword 863 /api/keyword/863 true 863 true Keyword 1059 /api/keyword/1059 true 1059 true Keyword 1121 /api/keyword/1121 true 1121 true Keyword 1188 /api/keyword/1188 true 1188 true Keyword 1404 /api/keyword/1404 true 1404 true Keyword 2023 /api/keyword/2023 true 2023 true Keyword 6276 /api/keyword/6276 true 6276 true Keyword 6852 /api/keyword/6852 true 6852 true Keyword 17403 /api/keyword/17403 true 17403 true Keyword 1009495 /api/keyword/1009495 true 1009495 true Keyword 1011672 /api/keyword/1011672 true 1011672 true Keyword 1012518 /api/keyword/1012518 true 1012518 true Keyword 1021451 /api/keyword/1021451 true 1021451 true Keyword 1026325 /api/keyword/1026325 true 1026325 true Keyword 1038843 /api/keyword/1038843 true 1038843 true Keyword 1042623 /api/keyword/1042623 true 1042623 true Keyword 1065832 /api/keyword/1065832 true 1065832 true Keyword 1101039 /api/keyword/1101039 true 1101039 true Keyword 1147277 /api/keyword/1147277 true 1147277 true Keyword 1185772 /api/keyword/1185772 true 1185772 true Keyword 1236595 /api/keyword/1236595 true 1236595 true Keyword 1493330 /api/keyword/1493330 true true Keyword 1495682 /api/keyword/1495682 true true Keyword 1505170 /api/keyword/1505170 true true Keyword 1541558 /api/keyword/1541558 true true Keyword 1560846 /api/keyword/1560846 true true Keyword 1625747 /api/keyword/1625747 true true Keyword 1633334 /api/keyword/1633334 true true Keyword 1715584 /api/keyword/1715584 true true Keyword 2014641 /api/keyword/2014641 true true Keyword 2180328 /api/keyword/2180328 true true Keyword 2729158 /api/keyword/2729158 true true Keyword 3484570 /api/keyword/3484570 true true Keyword 3484571 /api/keyword/3484571 true true SjrRating 11489344 /api/sjrrating/11489344 18 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1605 /api/classificationexternal/1605 true 1605 true D1 DIRECT true true /api/publication/35067177 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10095738"><a href="/gui2/?type=authors&mode=browse&sel=10095738" target="_blank">Ascsillan Anna A. (<span class="authorship-author-name">Ascsillán Anna</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Élettani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10040817"><a href="/gui2/?type=authors&mode=browse&sel=10040817" target="_blank">Kemeny Lajos V. ✉ (<span class="authorship-author-name">Kemény Lajos Vince</span> <span class="authorAux-mtmt"> Bőrgyógyászat, onkológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Élettani Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Bőr-, Nemikórtani és Bőronkológiai Klinika">BNBK</span>/HCEMM-SE Transzlációs Dermatológiai Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35067177" target="_blank">The Skin-Brain Axis: From UV and Pigmentation to Behaviour Modulation</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1661-6596">1661-6596</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1422-0067">1422-0067</a>)</span>: <span class="journal-volume">25</span> <span class="journal-issue">11</span> <span class="page"> Paper 6199. 19 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3390/ijms25116199" target="_blank" href="https://doi.org/10.3390/ijms25116199"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001245702400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001245702400001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85195851890" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85195851890"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38892387" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38892387&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Spectroscopy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Computer Science Applications&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Inorganic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Catalysis&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Molecular Biology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 16</span> | Független: 16 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 16 | Scopus jelölt:&nbsp;13 | WoS/Scopus jelölt:&nbsp;16 | DOI jelölt:&nbsp;16 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;35067177&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 35067177</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2024.06.24. 10:00 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> </div></div>