https://m2.mtmt.hu/ eng 2026-09-22 14:35 JournalArticle 35050942 VALIDATED true 0 false 2026-09-21T12:22:28.181+0000 2026-09-17T12:52:51.777+0000 2024-06-17T07:58:28.503+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2026-09-17T12:52:52.001+0000 2026-09-17T12:52:52.001+0000 2024-09-17T11:25:12.318+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Graziano, Francesca Prevalence and determinants of low QRS voltages and QRS fragmentation in children and adolescents undergoing sports pre-participation screening true true /api/journal/10028341 REVIEWED true false 10028341 false 10028341 true 2047-4873 2047-4881 Journal FOREIGN 31 12 1535 1542 1535 8 2024 Aims Low QRS voltages (LQRSV) in limb leads and QRS fragmentation (FQRS) are possible electrocardiographic signs of myocardial fibrosis and cardiomyopathy, but they are not listed in current criteria for interpreting athlete's electrocardiogram (ECG). We investigated the prevalence and determinants of LQRSV and FQRS in a cohort of young apparently healthy athletes undergoing pre-participation screening (PPS). Methods and results We analysed a consecutive series of 2140 ECG obtained during PPS of young athletes (mean age 12.5 +/- 2.6 years, 7-18-year-old, 49% males). The peak-to-peak QRS voltage was measured in all limb leads, and LQRSV were defined when maximum value was <0.5 mV. Fragmented QRS morphologies were grouped into five patterns. Lead aVR was not considered. Maximum peak-to-peak QRS voltage in limb leads was 1.4 +/- 0.4 mV, similar between younger and older athletes, but significantly lower in females than males (1.35 +/- 0.38 mV vs. 1.45 +/- 0.42 mV; P < 0.001). There was a weak correlation between maximal QRS voltages and body mass index (BMI), but not with type of sport or training load. Only five (0.2%) individuals showed LQRSV. At least one fragmented QRS complex was identified in 831 (39%) individuals but excluding the rSr ' pattern in V1-V2, only 10 (0.5%) showed FQRS in >= 2 contiguous leads. They were older than those without FQRS, but did not differ in terms of gender, BMI, type of sport, or training load. Conclusion Low QRS voltages in limb leads and FQRS in >= 2 contiguous leads excluding V1-V2 are rare in young apparently healthy athletes and are not related to the type and intensity of sport activity. Therefore, they may require additional testing to rule out an underlying disease particularly when other abnormalities are present. Lay summary Low QRS voltages (LQRSV) in limb leads and QRS fragmentation (FQRS) are possible electrocardiographic signs of myocardial fibrosis and cardiomyopathy. In our study, we analysed the occurrence and characteristics of FQRS and LQRSV in young athletes undergoing pre-participation screening. We found a low prevalence of these abnormalities, with only 0.2% showing LQRSV and 0.5% displaying FQRS.These abnormalities were not associated with factors such as gender, age, type of sport, or training load. 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10002 /api/language/10002 Angol English true 2 true PersonAuthorship 117933710 /api/authorship/117933710 1 0.111 true false false Author 10090599 /api/author/10090599 Graziano Francesca true true Graziano Francesca true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 117933711 /api/authorship/117933711 2 0.11111111 false false false Genta Oscar Edoardo true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 117933712 /api/authorship/117933712 3 0.11111111 false false false Manfrin Laura true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 117933713 /api/authorship/117933713 4 0.11111111 false false false Corrado Domenico true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 117933714 /api/authorship/117933714 5 0.11111111 false false false Brusamolin Laura true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 117933715 /api/authorship/117933715 6 0.11111111 false false false Giada Franco true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 117933716 /api/authorship/117933716 7 0.11111111 false false false Gerbino Luigi true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 117933717 /api/authorship/117933717 8 0.11111111 false false false Compagno Silvia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 117933718 /api/authorship/117933718 9 0.11111111 false true true Zorzi Alessandro true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 26677484 /api/publicationidentifier/26677484 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1093/eurjpc/zwae180 https://doi.org/10.1093/eurjpc/zwae180 false true PublicationIdentifier 26677485 /api/publicationidentifier/26677485 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001240654600001 https://www.webofscience.com/wos/woscc/full-record/001240654600001 false true PublicationIdentifier 27286630 /api/publicationidentifier/27286630 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85203473975 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85203473975 true true PublicationIdentifier 26677486 /api/publicationidentifier/26677486 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38775790 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38775790&dopt=Abstract false true Classification 12215 /api/classification/12215 true true Keyword 658 /api/keyword/658 true 658 true Keyword 4830 /api/keyword/4830 true 4830 true Keyword 1033613 /api/keyword/1033613 true 1033613 true Keyword 1053886 /api/keyword/1053886 true 1053886 true Keyword 1680069 /api/keyword/1680069 true true Keyword 2543489 /api/keyword/2543489 true true SjrRating 11446439 /api/sjrrating/11446439 35 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2705 /api/classificationexternal/2705 true 2705 true D1 DIRECT true true /api/publication/35050942 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10090599"><a href="/gui2/?type=authors&mode=browse&sel=10090599" target="_blank">Graziano Francesca (<span class="authorship-author-name">Graziano Francesca</span> <span class="authorAux-mtmt"> Cardiology, Sports Medicine</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Faculty of Sports Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Genta Oscar Edoardo </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Manfrin Laura </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Corrado Domenico </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Brusamolin Laura </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Giada Franco </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gerbino Luigi </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Compagno Silvia </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Zorzi Alessandro ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;35050942" target="_blank">Prevalence and determinants of low QRS voltages and QRS fragmentation in children and adolescents undergoing sports pre-participation screening</a></div> <div> <span class="journal-title">EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-4873">2047-4873</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-4881">2047-4881</a>)</span>: <span class="journal-volume">31</span> <span class="journal-issue">12</span> <span class="page"> pp 1535-1542 </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1093/eurjpc/zwae180" target="_blank" href="https://doi.org/10.1093/eurjpc/zwae180"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001240654600001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001240654600001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85203473975" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85203473975"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38775790" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38775790&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Epidemiology&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 11</span> | Independent citation: 5 | Self citation: 6 | Unknown citation: 0 | Number of citations in WoS: 11 | Number of citations in Scopus:&nbsp;9 | WoS/Scopus assigned:&nbsp;11 | Number of citations with DOI:&nbsp;11 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;35050942&sort=publishedYear,desc&sort=title"> Number of cited publications: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 35050942</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Last Modified: 2026.09.17. 14:52 Tamásné Gere (SE_KK_Admin5_GT, admin) </div> </div></div>