https://m2.mtmt.hu/ hun 2026-09-21 11:35 JournalArticle 34874083 VALIDATED true 0 false 2026-08-11T07:41:35.367+0000 2025-07-22T10:01:35.680+0000 2024-05-24T09:26:24.668+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2025-07-22T10:01:27.965+0000 2025-07-22T10:01:27.965+0000 2025-07-22T10:01:36.198+0000 true 10015546 Berhidi Anna /api/admin/10015546 Admin true 10015546 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType 104 true 10000359 true 1 /api/category/1 Category true 1 Solomon, Scott D. Baseline characteristics of patients with heart failure with mildly reduced or preserved ejection fraction: The FINEARTS-HF trial true true /api/journal/22711 REVIEWED true false 22711 false 22711 true 1388-9842 1879-0844 Journal FOREIGN 26 6 1334 1346 1334 13 2024 Aims To describe the baseline characteristics of participants in the FINEARTS-HF trial, contextualized with prior trials including patients with heart failure (HF) with mildly reduced and preserved ejection fraction (HFmrEF/HFpEF). The FINEARTS-HF trial is comparing the effects of the non-steroidal mineralocorticoid receptor antagonist finerenone with placebo in reducing cardiovascular death and total worsening HF events in patients with HFmrEF/HFpEF. Methods and results Patients with symptomatic HF, left ventricular ejection fraction (LVEF) >= 40%, estimated glomerular filtration rate >= 25 ml/min/1.73 m(2), elevated natriuretic peptide levels and evidence of structural heart disease were enrolled and randomized to finerenone titrated to a maximum of 40 mg once daily or matching placebo. We validly randomized 6001 patients to finerenone or placebo (mean age 72 +/- 10 years, 46% women). The majority were New York Heart Association functional class II (69%). The baseline mean LVEF was 53 +/- 8% (range 34-84%); 36% of participants had a LVEF <50% and 64% had a LVEF >= 50%. The median N-terminal pro-B-type natriuretic peptide (NT-proBNP) was 1041 (interquartile range 449-1946) pg/ml. A total of 1219 (20%) patients were enrolled during or within 7 days of a worsening HF event, and 3247 (54%) patients were enrolled within 3 months of a worsening HF event. Compared with prior large-scale HFmrEF/HFpEF trials, FINEARTS-HF participants were more likely to have recent (within 6 months) HF hospitalization and greater symptoms and functional limitations. Further, concomitant medications included a larger percentage of sodium-glucose cotransporter 2 inhibitors and angiotensin receptor-neprilysin inhibitors than previous trials. Conclusions FINEARTS-HF has enrolled a broad range of high-risk patients with HFmrEF and HFpEF. The trial will determine the safety and efficacy of finerenone in this population. 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V. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 26235455 /api/publicationidentifier/26235455 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1002/ejhf.3266 https://doi.org/10.1002/ejhf.3266 false true PublicationIdentifier 26235456 /api/publicationidentifier/26235456 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001218392300001 https://www.webofscience.com/wos/woscc/full-record/001218392300001 false true PublicationIdentifier 26235458 /api/publicationidentifier/26235458 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85192997126 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85192997126 false true PublicationIdentifier 26235457 /api/publicationidentifier/26235457 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38733212 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38733212&dopt=Abstract false true Classification 12221 /api/classification/12221 true true Keyword 125 /api/keyword/125 true 125 true Keyword 14471 /api/keyword/14471 true 14471 true Keyword 19878 /api/keyword/19878 true 19878 true Keyword 1042524 /api/keyword/1042524 true 1042524 true Keyword 1100778 /api/keyword/1100778 true 1100778 true Keyword 2230203 /api/keyword/2230203 true true Keyword 3385715 /api/keyword/3385715 true true SjrRating 11446420 /api/sjrrating/11446420 5 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2705 /api/classificationexternal/2705 true 2705 true D1 DIRECT true true /api/publication/34874083 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Solomon Scott D. ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002691"><a href="/gui2/?type=authors&mode=browse&sel=10002691" target="_blank">Merkely Bela (<span class="authorship-author-name">Merkely Béla Péter</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Sportorvostan Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Repülõ- és Űrorvostani Tanszék</span> ;&nbsp;&nbsp;&nbsp; et al. (58) </div> <div><a target="_blank" href="/api/publication/34874083?labelLang=hun">Összes szerző</a></div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34874083" target="_blank">Baseline characteristics of patients with heart failure with mildly reduced or preserved ejection fraction: The FINEARTS-HF trial</a></div> <div> <span class="journal-title">EUROPEAN JOURNAL OF HEART FAILURE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1388-9842">1388-9842</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1879-0844">1879-0844</a>)</span>: <span class="journal-volume">26</span> <span class="journal-issue">6</span> <span class="page"> pp 1334-1346 </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1002/ejhf.3266" target="_blank" href="https://doi.org/10.1002/ejhf.3266"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001218392300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001218392300001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85192997126" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85192997126"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38733212" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38733212&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 69</span> | Független: 24 | Függő: 45 | Nem jelölt: 0 | WoS jelölt: 66 | Scopus jelölt:&nbsp;64 | WoS/Scopus jelölt:&nbsp;69 | DOI jelölt:&nbsp;69 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34874083&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 8 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34874083</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Sokszerzős vagy csoportos szerzőségű szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2025.07.22. 12:01 Berhidi Anna (SE_KK_Admin5_BA, admin) </div> </div></div>