https://m2.mtmt.hu/ hun 2026-10-25 18:11 JournalArticle 34864485 VALIDATED true Funding Agency and Grant Number: Hungarian Research Foundation; National Research, Development and Innovation Office [TKP2021-EGA-31, RRF-2.3.1-21-2022-00015]; European Union [EFOP-3.6.3-VEKOP-16-2017-00009]; [OTKA ANN 139484] Funding text: We are grateful to the Hungarian Research Foundation (OTKA ANN 139484). The financial support of the National Research, Development and Innovation Office (TKP2021-EGA-31) is acknowledged. Project no. RRF-2.3.1-21-2022-00015 has been implemented with support provided by the European Union. E.E. acknowledges the grant of EFOP-3.6.3-VEKOP-16-2017-00009. 0 false 2026-10-24T13:33:24.718+0000 2026-06-30T11:44:06.444+0000 2024-05-21T06:07:03.587+0000 true 10015206 Áncsán Gizella /api/admin/10015206 Admin Áncsán Gizella (SE admin) true 10015206 2026-08-14T14:10:50.861+0000 2026-08-14T14:10:50.861+0000 2024-06-04T11:28:59.159+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) true Admin 10065569 /api/admin/10065569 Pécsi Éva (MTMT Közp 2,3, admin) Pécsi Éva true true 2026-03-26T10:43:39.163+0000 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Czompa, Andrea true true /api/journal/10003252 REVIEWED INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 true false 10003252 false 10003252 true 1661-6596 1422-0067 Journal FOREIGN 25 10 5523 5523 14 2024 A new, eco-friendly process utilising the green solvent propylene carbonate (PC) has been developed to perform N-alkylation of N-, O- and/or S-containing heterocyclic compounds. PC in these reactions served as both the reagent and solvent. Importantly, no genotoxic alkyl halides were required. No auxiliary was necessary when using anhydrous PC. Product formation includes nucleophilic substitution with the concomitant loss of water and carbon dioxide. Substrates prepared, including the newly invented PROTAC drugs, are widely used. Funding 2040963 /api/funding/2040963 (ANN139484) false true Funding 2040964 /api/funding/2040964 (TKP2021-EGA-31) false true Funding 2040965 /api/funding/2040965 Nemzeti Gyógyszerkutatási és Fejlesztési Laboratórium (PharmaLab)(RRF-2.3.1-21-2022-00015) Támogató: NKFIH false true Funding 2040966 /api/funding/2040966 Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009) Támogató: EFOP-VEKOP false true Funding 2040967 /api/funding/2040967 (KDP-2021) false true true 2024 true true true false true false GOLD 2026-10-24 true https://doi.org/10.3390/ijms25105523 2 0 2 2 0 2 2 2 2 2 2 2 2 2 0 0 2 2 2 2 0 1 1 Folyóiratcikk Journal Article 24 2 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2026 0 2 2 2 2 D1 false 10028378,10023665 false false false 2024-06-02T10:17:46.535+0000 Femtonics Kutató és Fejlesztő Korlátolt Felelős...; Hevesy György Kémia Doktori Iskola (ELTE / TTK); Mesterséges Transzporterek Kutatócsoport (HRN TTK / AKI); Szerves Vegytani Intézet (SE / GYTK) 6 30 4 7 0 true 10065569 Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 116652712 /api/authorship/116652712 Czompa, Andrea [Czompa, Andrea (Szerves-és gyógys...), szerző] Szerves Vegytani Intézet (SE / GYTK) 1 0.143 true false false Author 10023665 /api/author/10023665 Czompa Andrea (Szerves-és gyógyszerkémia) Czompa Andrea true 10023665 true Czompa Andrea true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116652713 /api/authorship/116652713 Bogdán, Dóra [Bogdán, Dóra (Szerves kémia, gy...), szerző] Szerves Vegytani Intézet (SE / GYTK); Mesterséges Transzporterek Kutatócsoport (HRN TTK / AKI) 2 0.143 false false false Author 10049468 /api/author/10049468 Bogdán Dóra (Szerves kémia, gyógyszerkémia) Bogdán Dóra true 10049468 true Bogdán Dóra true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116652714 /api/authorship/116652714 Balogh, Balázs [Balogh, Balázs (Szerves-és gyógys...), szerző] Szerves Vegytani Intézet (SE / GYTK) 3 0.143 false false false Author 10028378 /api/author/10028378 Balogh Balázs (Szerves-és gyógyszerkémia) Balogh Balázs true 10028378 true Balogh Balázs true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116652715 /api/authorship/116652715 Erdei, Eszter [Erdei, Eszter (Peptidszintézis, ...), szerző] Szerves Vegytani Intézet (SE / GYTK); Mesterséges Transzporterek Kutatócsoport (HRN TTK / AKI) 4 0.143 false false false Author 10095242 /api/author/10095242 Erdei Eszter (Peptidszintézis, szerkezetvizsgálat) Erdei Eszter true true Erdei Eszter true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116652716 /api/authorship/116652716 Selymes, Patrik 5 0.14285715 false false false Selymes Patrik true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116652717 /api/authorship/116652717 Csomos, Attila [Csomos, Attila (Kémia), szerző] Hevesy György Kémia Doktori Iskola (ELTE / TTK); Femtonics Kutató és Fejlesztő Korlátolt Felelős... 6 0.143 false false Author 10068523 /api/author/10068523 Csomos Attila (Kémia) Csomos Attila true true Csomos Attila true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116652718 /api/authorship/116652718 Mándity, István M. ✉ [Mándity, István (Gyógyszerkémia, g...), szerző] Szerves Vegytani Intézet (SE / GYTK); Mesterséges Transzporterek Kutatócsoport (HRN TTK / AKI) 7 0.143 false true true Author 10022837 /api/author/10022837 Mándity István (Gyógyszerkémia, gyógyszerkutatás) Mándity István true 10022837 true Mándity István M. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 26206628 /api/publicationidentifier/26206628 DOI: 10.3390/ijms25105523 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/ijms25105523 https://doi.org/10.3390/ijms25105523 false true PublicationIdentifier 26365319 /api/publicationidentifier/26365319 WoS: 001233127600001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001233127600001 https://www.webofscience.com/wos/woscc/full-record/001233127600001 true true PublicationIdentifier 32483119 /api/publicationidentifier/32483119 EDIT: 121096 SwordSource 92 /api/publicationsource/92 EDIT PublicationSourceType 10007 /api/publicationsourcetype/10007 Repozitórium true true true EDIT EDIT https://edit.elte.hu/handle/10831/@@@ true true 92 true GREEN true 121096 https://edit.elte.hu/handle/10831/121096 false true PublicationIdentifier 26301229 /api/publicationidentifier/26301229 Scopus: 85194217884 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85194217884 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85194217884 false true PublicationIdentifier 26313866 /api/publicationidentifier/26313866 PubMed: 38791560 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38791560 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38791560&dopt=Abstract true true SjrRating 11489344 /api/sjrrating/11489344 sjr:D1 (2024) Scopus - Organic Chemistry INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 18 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1605 /api/classificationexternal/1605 Scopus - Organic Chemistry true 1605 true D1 DIRECT true true Reference 53113106 /api/reference/53113106 1. 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(2024) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 25 10<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10023665"><a href="/gui2/?type=authors&mode=browse&sel=10023665" target="_blank">Czompa Andrea (<span class="authorship-author-name">Czompa Andrea</span> <span class="authorAux-mtmt"> Szerves-és gyógyszerkémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10049468"><a href="/gui2/?type=authors&mode=browse&sel=10049468" target="_blank">Bogdán Dóra (<span class="authorship-author-name">Bogdán Dóra</span> <span class="authorAux-mtmt"> Szerves kémia, gyógyszerkémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet; <span title="HUN-REN Természettudományi Kutatóközpont">HRN TTK</span>/<span title="Anyag- és Környezetkémiai Intézet">AKI</span>/Mesterséges Transzporterek Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10028378"><a href="/gui2/?type=authors&mode=browse&sel=10028378" target="_blank">Balogh Balázs (<span class="authorship-author-name">Balogh Balázs</span> <span class="authorAux-mtmt"> Szerves-és gyógyszerkémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10095242"><a href="/gui2/?type=authors&mode=browse&sel=10095242" target="_blank">Erdei Eszter (<span class="authorship-author-name">Erdei Eszter</span> <span class="authorAux-mtmt"> Peptidszintézis, szerkezetvizsgálat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet; <span title="HUN-REN Természettudományi Kutatóközpont">HRN TTK</span>/<span title="Anyag- és Környezetkémiai Intézet">AKI</span>/Mesterséges Transzporterek Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Selymes Patrik </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10068523"><a href="/gui2/?type=authors&mode=browse&sel=10068523" target="_blank">Csomos Attila (<span class="authorship-author-name">Csomos Attila</span> <span class="authorAux-mtmt"> Kémia</span>) </a> </span> <span class="author-affil"><span title="Eötvös Loránd Tudományegyetem">ELTE</span>/<span title="Természettudományi Kar">TTK</span>/Hevesy György Kémia Doktori Iskola; Femtonics Kutató és Fejlesztő Korlátolt Felelősségű Társaság</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10022837"><a href="/gui2/?type=authors&mode=browse&sel=10022837" target="_blank">Mándity István M. ✉ (<span class="authorship-author-name">Mándity István</span> <span class="authorAux-mtmt"> Gyógyszerkémia, gyógyszerkutatás</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet; <span title="HUN-REN Természettudományi Kutatóközpont">HRN TTK</span>/<span title="Anyag- és Környezetkémiai Intézet">AKI</span>/Mesterséges Transzporterek Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34864485" target="_blank">Sustainable and Safe N-alkylation of N-heterocycles by Propylene Carbonate under Neat Reaction Conditions</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1661-6596">1661-6596</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1422-0067">1422-0067</a>)</span>: <span class="journal-volume">25</span> <span class="journal-issue">10</span> <span class="page"> Paper 5523. 14 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/ijms25105523" target="_blank" href="https://doi.org/10.3390/ijms25105523"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001233127600001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001233127600001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="121096" target="_blank" href="https://edit.elte.hu/handle/10831/121096"> EDIT </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85194217884" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85194217884"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38791560" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38791560&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Spectroscopy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Computer Science Applications&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Inorganic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Catalysis&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Molecular Biology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 2</span> | Független: 2 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 2 | Scopus jelölt:&nbsp;2 | WoS/Scopus jelölt:&nbsp;2 | DOI jelölt:&nbsp;2 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34864485&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34864485</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (ANN139484), (TKP2021-EGA-31), Nemzeti Gyógyszerkutatási és Fejlesztési Laboratórium (PharmaLab)(RRF-2.3.1-21-2022-00015) Támogató: NKFIH, Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009) Támogató: EFOP-VEKOP, (KDP-2021) </div> <div class="lastModified">Utolsó módosítás: 2026.06.30. 13:44 Nemec Évi (MTMT Központi 3, admin) </div> <div class="lockedBy">Központi kezelésű 2026.03.26. 11:43 Pécsi Éva (MTMT Közp 2,3, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: Hungarian Research Foundation; National Research, Development and Innovation Office [TKP2021-EGA-31, RRF-2.3.1-21-2022-00015]; European Union [EFOP-3.6.3-VEKOP-16-2017-00009]; [OTKA ANN 139484] Funding text: We are grateful to the Hungarian Research Foundation (OTKA ANN 139484). The financial support of the National Research, Development and Innovat...</pre> </div></div>