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      <comment>Doctoral School, Semmelweis University, Budapest, 1085, Hungary            
            Faculty of Medicine, Semmelweis University, Budapest, 1085, Hungary            
            Department of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, 1082, Hungary            
            Heart and Vascular Centre, Semmelweis University, Budapest, 1122, Hungary            
            Department of Oxiology and Emergency Care, Faculty of Health Sciences, Semmelweis University, Budapest, 1088, Hungary            
            Export Date: 23 January 2025            
            Correspondence Address: Székely, A.; Department of Anesthesiology and Intensive Therapy, Hungary; email: szekelyandi64@gmail.com</comment>
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      <abstractText>Background: Frailty has been proven to be associated with mortality after orthotopic heart transplantation (OHT). The aim of our study was to determine the impact of frailty on mortality in the current era using pretransplant mechanical cardiac support (MCS). Methods: We retrospectively calculated the frailty scores of 471 patients undergoing OHT in a single institution between January 2012 and August 2022. The outcome was all-cause mortality. Results: The median survival time was 1987 days (IQR: 1487 days) for all patients. In total, 266 (56.5%) patients were categorized as nonfrail, 179 (38.0%) as prefrail, and 26 (5.5%) as frail. The survival rates were 0.73, 0.54, and 0.28 for nonfrail, prefrail, and frail patients, respectively. The frailty score was associated with mortality [HR: 1.34 (95% CI: 1.22–1.47, p &lt; 0.001)]. Among the components of the frailty score, age above 50 years, creatinine ≥ 3.0 mg/dL or prior dialysis, and hospitalization before OHT were independently associated with mortality. Continuous-flow left ventricular assist devices (CF-LVAD) were associated with an increased risk for all-cause mortality [AHR: 1.80 (95% CI: 1.01–3.24, p = 0.047)]. Conclusions: The components of the frailty score were not equally associated with mortality. Frailty and pretransplant MCS should be included in the risk estimation.</abstractText>
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          <label>23. Nagy 2021: Preoperative nutritional state is associated with mid- and long-term mortality after cardiac surgery., Ann. Palliat. Med., 10, p. 11333, DOI: 10.21037/apm-21-1015</label>
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          <label>24. Kobashigawa 2021: Frailty in heart transplantation: Report from the heart workgroup of a consensus conference on frailty., Am. J. Transplant., 21, p. 636, DOI: 10.1111/ajt.16207</label>
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          <label>25. Richter 2022: Frailty in cardiology: Definition, assessment and clinical implications for general cardiology. A consensus document of the Council for Cardiology Practice (CCP), Association for Acute Cardio Vascular Care (ACVC), Association of Cardiovascular Nursing and Allied Professions (ACNAP), European Association of Preventive Cardiology (EAPC), European Heart Rhythm Association (EHRA), Council on Valvular Heart Diseases (VHD), Council on Hypertension (CHT), Council of Cardio-Oncology (CCO), Working Group (WG) Aorta and Peripheral Vascular Diseases, WG e-Cardiology, WG Thrombosis, of the European Society of Cardiology, European Primary Care Cardiology Society (EPCCS)., Eur. J. Prev. Cardiol., 29, p. 216, DOI: 10.1093/eurjpc/zwaa167</label>
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          <label>26. Macdonald 2021: Frailty of the Heart Recipient., Transplantation, 105, p. 2352, DOI: 10.1097/TP.0000000000003692</label>
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          <label>27. Ayesta 2023: Frailty Is Common in Heart Transplant Candidates But Is Not Associated With Clinical Events and Is Reversible After Heart Transplantation., Am. J. Cardiol., 205, p. 28, DOI: 10.1016/j.amjcard.2023.07.110</label>
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          <doi>10.1016/j.amjcard.2023.07.110</doi>
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          <label>28. Jha 2016: Cognitive impairment improves the predictive validity of physical frailty for mortality in patients with advanced heart failure referred for heart transplantation., J. Heart Lung Transplant., 35, p. 1092, DOI: 10.1016/j.healun.2016.04.008</label>
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          <label>29. Tamimi 2023: Clinical Outcomes of Heart Transplant Recipients Admitted with COVID-19 Infection in 2020: A Nationwide Analysis., Curr. Probl. Cardiol., 48, p. 101996, DOI: 10.1016/j.cpcardiol.2023.101996</label>
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      </references>
      <link>/api/publication/34863328</link>
      <label>Szentgróti Rita et al. The Impact of Frailty Components and Preoperative Mechanical Cardiac Support Changes with Time after Heart Transplantation. (2024) BIOMEDICINES 2227-9059 12 5</label><template>&lt;div class=&quot;JournalArticle Publication short-list&quot;&gt; &lt;div class=&quot;authors&quot;&gt; &lt;span class=&quot;author-name&quot; mtid=&quot;10085179&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10085179&quot; target=&quot;_blank&quot;&gt;Szentgróti, Rita&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; &gt; Khochanskiy, Dmitry &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10075077&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10075077&quot; target=&quot;_blank&quot;&gt;Szécsi, Balázs&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; &gt; Németh, Flóra &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; 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&lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10022860&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10022860&quot; target=&quot;_blank&quot;&gt;Sax, Balázs&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10002691&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10002691&quot; target=&quot;_blank&quot;&gt;Merkely, Béla&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; et al. &lt;/div &gt;&lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;34863328&quot; mtid=&quot;34863328&quot; target=&quot;_blank&quot;&gt;The Impact of Frailty Components and Preoperative Mechanical Cardiac Support Changes with Time after Heart Transplantation&lt;/a&gt;&lt;/div&gt; &lt;div class=&quot;pub-info&quot;&gt; &lt;span class=&quot;journal-title&quot;&gt;BIOMEDICINES&lt;/span&gt; &lt;span class=&quot;journal-volume&quot;&gt;12&lt;/span&gt; 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&lt;span class=&quot;pub-category&quot;&gt;Tudományos&lt;/span&gt; &lt;div class=&quot;publication-citation&quot; style=&quot;margin-left: 0.5cm;&quot;&gt; &lt;span title=&quot;Nyilvános idézőközlemények összesen, említések nélkül&quot; class=&quot;citingPub-count&quot;&gt;Nyilvános idéző összesen: 1&lt;/span&gt; | Független: 0 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 1 | Scopus jelölt:&amp;nbsp;1 | WoS/Scopus jelölt:&amp;nbsp;1 | DOI jelölt:&amp;nbsp;1 &lt;/div&gt; &lt;/div&gt; &lt;/div&gt; &lt;/div&gt;</template><template2>&lt;div class=&quot;JournalArticle Publication long-list&quot;&gt;
&lt;div class=&quot;authors&quot;&gt;
	&lt;img title=&quot;Forrásközlemény&quot; style=&quot;float: left&quot; src=&quot;/frontend/resources/grid/publication-core-icon.png&quot;&gt;
	&lt;img title=&quot;Idézőközlemény&quot; style=&quot;float: left&quot; src=&quot;/frontend/resources/grid/publication-citation-icon.png&quot;&gt;

		&lt;div class=&quot;autype autype0&quot;&gt;				&lt;span class=&quot;author-name&quot; mtid=&quot;10085179&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10085179&quot; target=&quot;_blank&quot;&gt;Szentgróti Rita
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Szentgróti Rita&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; aneszteziológia és intenzív terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; &gt;Khochanskiy Dmitry
    &lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10075077&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10075077&quot; target=&quot;_blank&quot;&gt;Szécsi Balázs
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Szécsi Balázs&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Aneszteziológia és Intenzív Terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; &gt;Németh Flóra
    &lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10065615&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10065615&quot; target=&quot;_blank&quot;&gt;Szabó András
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Szabó András&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; aneszteziológia és intenzív terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Aneszteziológiai és Intenzív Terápiás Klinika&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10077047&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10077047&quot; target=&quot;_blank&quot;&gt;Koritsánszky Kinga
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Koritsánszky Kinga Bianka&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Aneszteziológia Intenzív Terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10090356&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10090356&quot; target=&quot;_blank&quot;&gt;Vereb Alexandra
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Vereb Alexandra&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Aneszteziológia és intenzív terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10037325&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10037325&quot; target=&quot;_blank&quot;&gt;Cserép Zsuzsanna
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Cserép Zsuzsanna&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; belgyógyászat&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10022860&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10022860&quot; target=&quot;_blank&quot;&gt;Sax Balázs
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Sax Balázs&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Orvostudományok&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10002691&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10002691&quot; target=&quot;_blank&quot;&gt;Merkely Béla
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Merkely Béla Péter&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Kardiológia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/&lt;span title=&quot;Városmajori Szív- és Érgyógyászati Klinika&quot;&gt;VAROSMAJOR_SZÍVÉRGYÓGY&lt;/span&gt;/Kardiológia Központ - Kardiológiai Tanszék; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/&lt;span title=&quot;Városmajori Szív- és Érgyógyászati Klinika&quot;&gt;VAROSMAJOR_SZÍVÉRGYÓGY&lt;/span&gt;/Sportorvostan Tanszék; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/&lt;span title=&quot;Városmajori Szív- és Érgyógyászati Klinika&quot;&gt;VAROSMAJOR_SZÍVÉRGYÓGY&lt;/span&gt;/Repülõ- és Űrorvostani Tanszék&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10021986&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10021986&quot; target=&quot;_blank&quot;&gt;Székely Andrea ✉
	            (&lt;span class=&quot;authorship-author-name&quot;&gt;Székely Andrea&lt;/span&gt;
	            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Aneszteziológia és intenzív terápia, szívsebészet&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Aneszteziológiai és Intenzív Terápiás Klinika; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Egészségtudományi Kar&quot;&gt;ETK2007&lt;/span&gt;/Oxiológiai és Sürgősségi Ellátás Tanszék; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Intenzív Terápiás Klinika&lt;/span&gt;

				    &lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;34863328&quot; target=&quot;_blank&quot;&gt;The Impact of Frailty Components and Preoperative Mechanical Cardiac Support Changes with Time after Heart Transplantation&lt;/a&gt;&lt;/div&gt;    &lt;div&gt;		&lt;span class=&quot;journal-title&quot;&gt;BIOMEDICINES&lt;/span&gt;

        &lt;span class=&quot;journal-issn&quot;&gt;( &lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/2227-9059&quot;&gt;2227-9059&lt;/a&gt;)&lt;/span&gt;:
		&lt;span class=&quot;journal-volume&quot;&gt;12&lt;/span&gt; &lt;span class=&quot;journal-issue&quot;&gt;5&lt;/span&gt;
&lt;span class=&quot;page&quot;&gt;
		Paper 1114.
	 11 p. 
&lt;/span&gt;		 &lt;span class=&quot;year&quot;&gt;(2024)&lt;/span&gt;  
    &lt;/div&gt;
&lt;div class=&quot;pub-footer&quot;&gt;
    

	&lt;span class=&quot;language&quot; xmlns=&quot;http://www.w3.org/1999/html&quot;&gt;Nyelv:
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	&lt;OnlyViewableByAuthor&gt;&lt;div class=&quot;ratings&quot;&gt;
				&lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q1&lt;/div&gt;
				&lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q1&lt;/div&gt;
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		| Független: 0
		| Függő: 1
		| Nem jelölt: 0
		| WoS jelölt: 1 
		|  Scopus jelölt:&amp;nbsp;1 
		|  WoS/Scopus jelölt:&amp;nbsp;1 
		|  DOI jelölt:&amp;nbsp;1 
		
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			Idézett közlemények száma: 2
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    &lt;div class=&quot;mtid&quot;&gt;&lt;span class=&quot;long-pub-mtid&quot;&gt;Közlemény: 34863328&lt;/span&gt;
    | &lt;span class=&quot;status-data status-VALIDATED&quot;&gt; 	Egyeztetett
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Forrás	 Idéző
	
	
    | &lt;span class=&quot;type-subtype&quot;&gt;Folyóiratcikk
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			)
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      		| &lt;span class=&quot;pub-category&quot;&gt;Tudományos&lt;/span&gt;
	| &lt;span class=&quot;publication-sourceOfData&quot;&gt;kézi felvitel&lt;/span&gt;
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&lt;div class=&quot;lastModified&quot;&gt;Utolsó módosítás: 2024.11.04. 16:27 Olasz Tamás (SE_KK_Admin5_OT, admin)
&lt;/div&gt;




	&lt;pre class=&quot;comment&quot; style=&quot;margin-top: 0; margin-bottom: 0;&quot;&gt;&lt;u&gt;Megjegyzés&lt;/u&gt;: Doctoral School, Semmelweis University, Budapest, 1085, Hungary            
            Faculty of Medicine, Semmelweis University, Budapest, 1085, Hungary            
            Department of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, 1082, Hungary            
            Heart and Vascular Centre, Semmelweis University, Budapest, 1122, Hungary            
        ...&lt;/pre&gt;
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