https://m2.mtmt.hu/ hun 2026-04-30 03:58 JournalArticle 34801936 VALIDATED true Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, 1085, Hungary For Human Genome Foundation, Budapest, 1094, Hungary Pediatrics Centre, Tűzoltó Street Department, Semmelweis University, Budapest, 1085, Hungary Nanomedicine Research and Education Center, Department of Translational Medicine, Semmelweis University, Budapest, 1085, Hungary SeroScience LCC, Budapest, 1089, Hungary Cited By :1 Export Date: 7 February 2025 Correspondence Address: Kovács, Á.F.; For Human Genome FoundationHungary; email: kovacs.arpad@semmelweis.hu 0 false 2026-01-01T15:53:10.694+0000 2024-05-17T06:46:08.048+0000 2024-04-20T11:12:05.133+0000 true 10053336 Kovács Árpád Ferenc /api/author/10053336 Author Kovács Árpád Ferenc (genetika, immunológia) true 10053336 2025-02-07T09:51:04.520+0000 2024-05-07T06:30:48.243+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Fekete, Nóra true true /api/journal/10051562 REVIEWED CELLS 2073-4409 true false 10051562 false 10051562 true 2073-4409 Journal FOREIGN 13 8 706 706 10 2024 Background: Fabry disease is a progressive, X chromosome-linked lysosomal storage disorder with multiple organ dysfunction. Due to the absence or reduced activity of alpha-galactosidase A (AGAL), glycosphingolipids, primarily globotriaosyl-ceramide (Gb3), concentrate in cells. In heterozygous women, symptomatology is heterogenous and currently routinely used fluorometry-based assays measuring mean activity mostly fail to uncover AGAL dysfunction. The aim was the development of a flow cytometry assay to measure AGAL activity in individual cells. Methods: Conventional and multispectral imaging flow cytometry was used to detect AGAL activity. Specificity was validated using the GLA knockout (KO) Jurkat cell line and AGAL inhibitor 1-deoxygalactonojirimycin. The GLA KO cell line was generated via CRISPR-Cas9-based transfection, validated with exome sequencing, gene expression and substrate accumulation. Results: Flow cytometric detection of specific AGAL activity is feasible with fluorescently labelled Gb3. In the case of Jurkat cells, a substrate concentration of 2.83 nmol/mL and 6 h of incubation are required. Quenching of the aspecific exofacial binding of Gb3 with 20% trypan blue solution is necessary for the specific detection of lysosomal substrate accumulation. Conclusion: A flow cytometry-based assay was developed for the quantitative detection of AGAL activity at the single-cell level, which may contribute to the diagnosis of Fabry patients. Funding 2039923 /api/funding/2039923 (PD_21 138521) false true true 2024 true true true false true false GOLD 2026-01-01 false https://www.mdpi.com/journal/cells 1 0 1 1 0 1 1 1 1 1 1 1 1 1 0 0 1 1 1 1 0 1 1 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 1 1 1 Q1 false 10053336 false false false 2024-05-06T06:30:47.967+0000 Genetikai, Sejt- és Immunbiológiai Intézet (SE / AOK / I); Gyermekgyógyászati Klinika (SE / AOK / K); Nanomedicina Kutató és Oktató Központ (SE / AOK / I / TMI); Transzlációs Medicina Intézet (SE / AOK / I) 6 23 4 6 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 116267252 /api/authorship/116267252 Fekete, Nóra [Fekete, Nóra (áramlási citometr...), szerző] Genetikai, Sejt- és Immunbiológiai Intézet (SE / AOK / I) 1 0.167 true false false Author 10079998 /api/author/10079998 Fekete Nóra (áramlási citometriás módszerfejlesztések, extracelluláris vezikulák vizsgálata) Fekete Nóra true true Fekete Nóra true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116267253 /api/authorship/116267253 Li, Luca Kamilla [Li, Luca Kamilla (Genetika), szerző] Gyermekgyógyászati Klinika (SE / AOK / K) 2 0.167 false false false Author 10092066 /api/author/10092066 Li Luca Kamilla (Genetika) Li Luca Kamilla true true Li Luca Kamilla true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116267254 /api/authorship/116267254 Kozma, Gergely Tibor [Kozma, Gergely Tibor (Immunológia, Mole...), szerző] Nanomedicina Kutató és Oktató Központ (SE / AOK / I / TMI); Transzlációs Medicina Intézet (SE / AOK / I) 3 0.167 false false false Author 10024742 /api/author/10024742 Kozma Gergely Tibor (Immunológia, Molekuláris biológia) Kozma Gergely Tibor true 10024742 true Kozma Gergely Tibor true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116267255 /api/authorship/116267255 Fekete, György [Fekete, György (Gyermekgyógyászat...), szerző] Gyermekgyógyászati Klinika (SE / AOK / K) 4 0.167 false false false Author 1318616 /api/author/1318616 Fekete György (Gyermekgyógyászat, klinikai genetika, klinikofarmakológia) Fekete György true 1318616 true Fekete György true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116267256 /api/authorship/116267256 Pállinger, Éva [Pállinger, Éva (Immunológia), szerző] Genetikai, Sejt- és Immunbiológiai Intézet (SE / AOK / I) 5 0.167 false false false Author 10015589 /api/author/10015589 Pállinger Éva (Immunológia) Pállinger Éva true 10015589 true Pállinger Éva true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 116267257 /api/authorship/116267257 Kovács, Árpád Ferenc ✉ [Kovács, Árpád Ferenc (genetika, immunol...), szerző] Gyermekgyógyászati Klinika (SE / AOK / K) 6 0.167 false true true Author 10053336 /api/author/10053336 Kovács Árpád Ferenc (genetika, immunológia) Kovács Árpád Ferenc true 10053336 true Kovács Árpád Ferenc true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 26036976 /api/publicationidentifier/26036976 DOI: 10.3390/cells13080706 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.3390/cells13080706 https://doi.org/10.3390/cells13080706 false true PublicationIdentifier 26198704 /api/publicationidentifier/26198704 WoS: 001210682400001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001210682400001 https://www.webofscience.com/wos/woscc/full-record/001210682400001 true true PublicationIdentifier 26144832 /api/publicationidentifier/26144832 Scopus: 85191458388 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85191458388 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85191458388 true true PublicationIdentifier 26144834 /api/publicationidentifier/26144834 PubMed: 38667321 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38667321 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38667321&dopt=Abstract true true SjrRating 11443701 /api/sjrrating/11443701 sjr:Q1 (2024) Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous) CELLS 2073-4409 40 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1301 /api/classificationexternal/1301 Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous) true 1301 true Q1 DIRECT true true Reference 52099819 /api/reference/52099819 1. Peters 2020: Treatable Lysosomal Storage Diseases in the Advent of Disease-Specific Therapy., Intern. Med. J., 50, p. 5, DOI: 10.1111/imj.15100 1 10.1111/imj.15100 false true Reference 52099820 /api/reference/52099820 2. Platt 2018: Lysosomal Storage Diseases., Nat. Rev. Dis. Primers, 4, p. 27, DOI: 10.1038/s41572-018-0025-4 2 10.1038/s41572-018-0025-4 false true Reference 52099821 /api/reference/52099821 3. Ellaway 2016: Paediatric Fabry Disease., Transl. Pediatr., 5, p. 37 3 false true Reference 52099822 /api/reference/52099822 4. Li 2023: Clinical Features and Enzyme Replacement Therapy in 10 Children with Fabry Disease., Front. Pediatr., 11, p. 1084336, DOI: 10.3389/fped.2023.1084336 4 10.3389/fped.2023.1084336 false true Reference 52099823 /api/reference/52099823 5. Weng 2023: Population Frequency of Undiagnosed Fabry Disease in the General Population., Kidney Int. Rep., 8, p. 1373, DOI: 10.1016/j.ekir.2023.04.009 5 10.1016/j.ekir.2023.04.009 false true Reference 52099824 /api/reference/52099824 6. Schiffmann 2016: Is It Fabry Disease?., Genet. Med., 18, p. 1181, DOI: 10.1038/gim.2016.55 6 10.1038/gim.2016.55 false true Reference 52099825 /api/reference/52099825 7. Oliveira 2019: Multiple Phenotypic Domains of Fabry Disease and Their Relevance for Establishing Genotype–Phenotype Correlations., Appl. Clin. Genet., 12, p. 35, DOI: 10.2147/TACG.S146022 7 10.2147/TACG.S146022 false true Reference 52099826 /api/reference/52099826 8. Yogasundaram 2018: Elevated Inflammatory Plasma Biomarkers in Patients with Fabry Disease: A Critical Link to Heart Failure with Preserved Ejection Fraction., J. Am. Heart Assoc. Cardiovasc. Cerebrovasc. Dis., 7, p. e009098, DOI: 10.1161/JAHA.118.009098 8 10.1161/JAHA.118.009098 false true Reference 52099827 /api/reference/52099827 9. Weidemann 2013: Fibrosis: A Key Feature of Fabry Disease with Potential Therapeutic Implications., Orphanet J. Rare Dis., 8, p. 116, DOI: 10.1186/1750-1172-8-116 9 10.1186/1750-1172-8-116 false true Reference 52099828 /api/reference/52099828 10. Kok, K., Zwiers, K.C., Boot, R.G., Overkleeft, H.S., Aerts, J.M.F.G., and Artola, M. (2021). Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions. Biomolecules, 11., DOI: 10.3390/biom11020271 10 10.3390/biom11020271 false true Reference 52099829 /api/reference/52099829 11. Hsu 2019: Identification of Lysosomal and Extralysosomal Globotriaosylceramide (Gb3) Accumulations before the Occurrence of Typical Pathological Changes in the Endomyocardial Biopsies of Fabry Disease Patients., Genet. Med., 21, p. 224, DOI: 10.1038/s41436-018-0010-z 11 10.1038/s41436-018-0010-z false true Reference 52099830 /api/reference/52099830 12. Aerts 2008: Elevated Globotriaosylsphingosine Is a Hallmark of Fabry Disease., Proc. Natl. Acad. Sci. USA, 105, p. 2812, DOI: 10.1073/pnas.0712309105 12 10.1073/pnas.0712309105 false true Reference 52099831 /api/reference/52099831 13. Sirrs, S., Bichet, D.G., Iwanochko, M.R., Khan, A., Moore, D., Oudit, G., and West, M.L. (2019). Canadian Fabry Disease Treatment Guidelines. 13 false true Reference 52099832 /api/reference/52099832 14. Smid 2014: Uncertain Diagnosis of Fabry Disease: Consensus Recommendation on Diagnosis in Adults with Left Ventricular Hypertrophy and Genetic Variants of Unknown Significance., Int. J. Cardiol., 177, p. 400, DOI: 10.1016/j.ijcard.2014.09.001 14 10.1016/j.ijcard.2014.09.001 false true Reference 52099833 /api/reference/52099833 15. Svarstad 2015: Chronic Kidney Disease and an Uncertain Diagnosis of Fabry Disease: Approach to a Correct Diagnosis., Mol. Genet. Metab., 114, p. 242, DOI: 10.1016/j.ymgme.2014.08.007 15 10.1016/j.ymgme.2014.08.007 false true Reference 52099834 /api/reference/52099834 16. Ponyi 2021: Fabry-Betegség: Diagnosztikai Útmutató., Gyermekgyógyászat, 72, p. 73 16 false true Reference 52099835 /api/reference/52099835 17. Miller 2023: ACMG SF v3.2 List for Reporting of Secondary Findings in Clinical Exome and Genome Sequencing: A Policy Statement of the American College of Medical Genetics and Genomics (ACMG)., Genet. Med., 25, p. 100866, DOI: 10.1016/j.gim.2023.100866 17 10.1016/j.gim.2023.100866 false true Reference 52099836 /api/reference/52099836 18. Hughes 2022: Do Clinical Guidelines Facilitate or Impede Drivers of Treatment in Fabry Disease?., Orphanet J. Rare Dis., 17, p. 42, DOI: 10.1186/s13023-022-02181-4 18 10.1186/s13023-022-02181-4 false true Reference 52099837 /api/reference/52099837 19. Linthorst 2008: Enzyme Activity for Determination of Presence of Fabry Disease in Women Results in 40% False-Negative Results., J. Am. Coll. Cardiol., 51, p. 2082, DOI: 10.1016/j.jacc.2008.02.050 19 10.1016/j.jacc.2008.02.050 false true Reference 52099838 /api/reference/52099838 20. Germain 2022: An Expert Consensus on Practical Clinical Recommendations and Guidance for Patients with Classic Fabry Disease., Mol. Genet. Metab., 137, p. 49, DOI: 10.1016/j.ymgme.2022.07.010 20 10.1016/j.ymgme.2022.07.010 false true Reference 52099839 /api/reference/52099839 21. Andrade 2008: Screening for Fabry Disease in Patients with Chronic Kidney Disease: Limitations of Plasma α-Galactosidase Assay as a Screening Test., Clin. J. Am. Soc. Nephrol., 3, p. 139, DOI: 10.2215/CJN.02490607 21 10.2215/CJN.02490607 false true Reference 52099840 /api/reference/52099840 22. Daitx 2012: Comparison between Alpha-Galactosidase A Activity in Blood Samples Collected on Filter Paper, Leukocytes and Plasma., Clin. Biochem., 45, p. 1233, DOI: 10.1016/j.clinbiochem.2012.04.030 22 10.1016/j.clinbiochem.2012.04.030 false true Reference 52099841 /api/reference/52099841 23. Jeon, Y.J., Jung, N., Park, J.W., Park, H.Y., and Jung, S.C. (2015). Epithelial–Mesenchymal Transition in Kidney Tubular Epithelial Cells Induced by Globotriaosylsphingosine and Globotriaosylceramide. PLoS ONE, 10., DOI: 10.1371/journal.pone.0136442 23 10.1371/journal.pone.0136442 false true Reference 52099842 /api/reference/52099842 24. Illien 2016: Quantitative Fluorescence Spectroscopy and Flow Cytometry Analyses of Cell-Penetrating Peptides Internalization Pathways: Optimization, Pitfalls, Comparison with Mass Spectrometry Quantification., Sci. Rep., 6, p. 36938, DOI: 10.1038/srep36938 24 10.1038/srep36938 false true Reference 52099843 /api/reference/52099843 25. Busetto 2004: A Single-Step, Sensitive Flow Cytofluorometric Assay for the Simultaneous Assessment of Membrane-Bound and Ingested Candida Albicans in Phagocytosing Neutrophils., Cytom. Part. A, 58A, p. 201, DOI: 10.1002/cyto.a.20014 25 10.1002/cyto.a.20014 false true Reference 52099844 /api/reference/52099844 26. Castellanos 2020: Upregulation of ASIC1a Channels in an in Vitro Model of Fabry Disease., Neurochem. Int., 140, p. 104824, DOI: 10.1016/j.neuint.2020.104824 26 10.1016/j.neuint.2020.104824 false true Reference 52099845 /api/reference/52099845 27. Fernández-Delgado, M., Sendra, L., Herrero, M.J., Olivera-Pasquini, G.G., Batista-Duharte, A., and Aliño, S.F. (2022). Study of Oligonucleotides Access and Distribution in Human Peripheral Blood Mononuclear Cells. Int. J. Mol. Sci., 23., DOI: 10.3390/ijms23105839 27 10.3390/ijms23105839 false true Reference 52099846 /api/reference/52099846 28. Hallows 2023: Optimizing Human α-Galactosidase for Treatment of Fabry Disease., Sci. Rep., 13, p. 4748, DOI: 10.1038/s41598-023-31777-4 28 10.1038/s41598-023-31777-4 false true Reference 52099847 /api/reference/52099847 29. Kingsmore 2022: Dispatches from Biotech Beginning BeginNGS: Rapid Newborn Genome Sequencing to End the Diagnostic and Therapeutic Odyssey., Am. J. Med. Genet. C Semin. Med. Genet., 190, p. 243, DOI: 10.1002/ajmg.c.32005 29 10.1002/ajmg.c.32005 false true Reference 52099848 /api/reference/52099848 30. Wojcik 2021: Discordant Results between Conventional Newborn Screening and Genomic Sequencing in the BabySeq Project., Genet. Med., 23, p. 1372, DOI: 10.1038/s41436-021-01146-5 30 10.1038/s41436-021-01146-5 false true Reference 52099849 /api/reference/52099849 31. Spiekerkoetter 2023: Genomic Newborn Screening: Are We Entering a New Era of Screening?., J. Inherit. Metab. Dis., 46, p. 778, DOI: 10.1002/jimd.12650 31 10.1002/jimd.12650 false true Reference 52099850 /api/reference/52099850 32. Kovács, Á.F., Némethi, Z., Abonyi, T., Fekete, G., and Kovács, G.T. (2022). Enhancing Molecular Testing for Effective Delivery of Actionable Gene Diagnostics. Bioengineering, 9., DOI: 10.3390/bioengineering9120745 32 10.3390/bioengineering9120745 false true /api/publication/34801936 Fekete Nóra et al. Flow Cytometry-Based Assay to Detect Alpha Galactosidase Enzymatic Activity at the Cellular Level. (2024) CELLS 2073-4409 13 8<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10079998"><a href="/gui2/?type=authors&mode=browse&sel=10079998" target="_blank">Fekete Nóra (<span class="authorship-author-name">Fekete Nóra</span> <span class="authorAux-mtmt"> áramlási citometriás módszerfejlesztések, extra...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Genetikai, Sejt- és Immunbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10092066"><a href="/gui2/?type=authors&mode=browse&sel=10092066" target="_blank">Li Luca Kamilla (<span class="authorship-author-name">Li Luca Kamilla</span> <span class="authorAux-mtmt"> Genetika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Gyermekgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024742"><a href="/gui2/?type=authors&mode=browse&sel=10024742" target="_blank">Kozma Gergely Tibor (<span class="authorship-author-name">Kozma Gergely Tibor</span> <span class="authorAux-mtmt"> Immunológia, Molekuláris biológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Transzlációs Medicina Intézet">TMI</span>/Nanomedicina Kutató és Oktató Központ; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="1318616"><a href="/gui2/?type=authors&mode=browse&sel=1318616" target="_blank">Fekete György (<span class="authorship-author-name">Fekete György</span> <span class="authorAux-mtmt"> Gyermekgyógyászat, klinikai genetika, klinikofa...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Gyermekgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10015589"><a href="/gui2/?type=authors&mode=browse&sel=10015589" target="_blank">Pállinger Éva (<span class="authorship-author-name">Pállinger Éva</span> <span class="authorAux-mtmt"> Immunológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Genetikai, Sejt- és Immunbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10053336"><a href="/gui2/?type=authors&mode=browse&sel=10053336" target="_blank">Kovács Árpád Ferenc ✉ (<span class="authorship-author-name">Kovács Árpád Ferenc</span> <span class="authorAux-mtmt"> genetika, immunológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Gyermekgyógyászati Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34801936" target="_blank">Flow Cytometry-Based Assay to Detect Alpha Galactosidase Enzymatic Activity at the Cellular Level</a></div> <div> <span class="journal-title">CELLS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2073-4409">2073-4409</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">8</span> <span class="page"> Paper 706. 10 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3390/cells13080706" target="_blank" href="https://doi.org/10.3390/cells13080706"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001210682400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001210682400001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85191458388" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85191458388"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38667321" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38667321&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | Scopus jelölt:&nbsp;1 | WoS/Scopus jelölt:&nbsp;1 | DOI jelölt:&nbsp;1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34801936&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34801936</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (PD_21 138521) </div> <div class="lastModified">Utolsó módosítás: 2024.05.17. 08:46 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, 1085, Hungary For Human Genome Foundation, Budapest, 1094, Hungary Pediatrics Centre, Tűzoltó Street Department, Semmelweis University, Budapest, 1085, Hungary Nanomedicine Research and Education Center, Department of Translational Medicine, Se...</pre> </div></div>