https://m2.mtmt.hu/ hun 2026-09-21 00:29 JournalArticle 34801778 VALIDATED true Funding Agency and Grant Number: Hungarian Academy of Sciences [BO/00451/20/5]; New National Excellence Program [UNKP-21-5-SE-3]; Ministry for Innovation and Technology from the source of the National Research Development and Innovation Fund [K139059] Funding text: T. S. was supported by a Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (BO/00451/20/5) and by the New National Excellence Program (UNKP-21-5-SE-3) and the K139059 grant of the Ministry for Innovation and Technology from the source of the National Research Development and Innovation Fund. 0 false 2026-09-05T14:03:54.045+0000 2026-06-18T17:20:01.476+0000 2024-04-19T19:26:47.810+0000 true 10081959 Szalóky-Siki Ágnes /api/admin/10081959 Admin true 2026-06-18T17:20:01.414+0000 2025-10-08T08:39:12.926+0000 true 10062062 Gere Tamásné /api/admin/10062062 Admin true 10062062 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Olah, Csilla Estimation of the incidence of urachal cancer : A systematic review and meta-analysis of registry-based studies true true /api/journal/10001003 REVIEWED true false 10001003 false 10001003 true 1078-1439 1873-2496 Journal FOREIGN 42 7 221.e1 221.e7 221.e1 7 2024 Urachal cancer (UrC) is a rare disease with limited availability of representative incidence and clinical data. Although, the prevalence is accounting for less than 1% of bladder tumors, the 5-year survival rate is around only 50% for patients with resectable tumors, and even worse for patients with metastatic disease. Due to the lack of comprehensive prospective studies, our current knowledge of UrC is still limited.The present study aimed to summarize the available registry-based studies with unselected UrC patients to evaluate its incidence and clinicopathological characteristics.We conducted a systematic literature search of registry-based UrC publications on the 15th of May 2023 in 5 databases, which identified 4,748 publications. After duplicate removal and selection by 2 independent investigators, 6 publications proved to be appropriate for the final meta-analysis. Estimated incidence and clinicopathological parameters were extracted.Estimated incidence ranged between 0.022 and 0.060/ 100.000 person-years, with the highest occurrence in Japan and the lowest in Canada, while the random effect model calculated an overall incidence rate of 0.04 (95%CI: 0.03-0.05) 100.000 person-years. The median age at first diagnosis was 60 years (range: 58-64). The female to male ratio was 2:3. Lymph node or distant metastases were present in 9% and 14% of patients. The predominant tumour type was adenocarcinoma (86%) followed by urothelial carcinoma (12%) and squamous cell carcinoma (2%). The 5-year survival rate was 51.0% with 95%CI: 45.2-57.4.Our study provides an up-to-date comparison of estimated incidence rates between 6 countries of 3 continents based on rigorously selected registry-based studies. The results suggest low incidence rates for UrC with considerable geographic differences. The present meta-analysis provides unbiased registry-based data on the incidence, clinicopathological parameters and survival of UrC. 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Transzlációs Medicina Intézet (PTE / ÁOK); Transzlációs Medicina Központ (SE / KSZE); Urológiai Klinika (SE / AOK / K) 7 41 4 9 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 116265709 /api/authorship/116265709 1 0.11111111 true false false Olah Csilla true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 116265710 /api/authorship/116265710 2 0.111 false false false Author 10035288 /api/author/10035288 Kubik András true 10035288 true Kubik András true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 116265711 /api/authorship/116265711 3 0.111 false false false Author 10045289 /api/author/10045289 Mátrai Péter true 10045289 true Mátrai Péter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 116265712 /api/authorship/116265712 4 0.111 false false false Author 10086474 /api/author/10086474 Engh Marie Anne true true Engh Marie Anne true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 116265713 /api/authorship/116265713 5 0.111 false false false Author 10089630 /api/author/10089630 Barna Viktória true true Barna Viktória true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 116265714 /api/authorship/116265714 6 0.111 false false false Author 10002629 /api/author/10002629 Hegyi Péter true 10002629 true Hegyi Péter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 116265715 /api/authorship/116265715 7 0.11111111 false false false Reis Henning true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 116265716 /api/authorship/116265716 8 0.111 false false false Author 10013343 /api/author/10013343 Nyirády Péter true 10013343 true Nyirády Péter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 116265717 /api/authorship/116265717 9 0.111 false true true Author 10052466 /api/author/10052466 Szarvas Tibor true 10052466 true Szarvas Tibor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 26036702 /api/publicationidentifier/26036702 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1016/j.urolonc.2024.03.011 https://doi.org/10.1016/j.urolonc.2024.03.011 false true PublicationIdentifier 26921866 /api/publicationidentifier/26921866 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001272964300001 https://www.webofscience.com/wos/woscc/full-record/001272964300001 false true PublicationIdentifier 26041847 /api/publicationidentifier/26041847 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85190341786 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85190341786 false true PublicationIdentifier 26036701 /api/publicationidentifier/26036701 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38627107 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38627107&dopt=Abstract false true PublicationIdentifier 31944268 /api/publicationidentifier/31944268 PlainSource 40 /api/publicationsource/40 PublicationSourceType 10006 /api/publicationsourcetype/10006 true true true Egyéb URL Other URL @@@ true true 40 true NONE IDENTICAL https://www.scopus.com/pages/publications/85190341786?origin=resultslist https://www.scopus.com/pages/publications/85190341786?origin=resultslist false true Keyword 3375201 /api/keyword/3375201 true true SjrRating 11505766 /api/sjrrating/11505766 24 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2748 /api/classificationexternal/2748 true 2748 true Q1 DIRECT true true /api/publication/34801778 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Olah Csilla </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10035288"><a href="/gui2/?type=authors&mode=browse&sel=10035288" target="_blank">Kubik András (<span class="authorship-author-name">Kubik András</span> <span class="authorAux-mtmt"> Urológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Urológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10045289"><a href="/gui2/?type=authors&mode=browse&sel=10045289" target="_blank">Mátrai Péter (<span class="authorship-author-name">Mátrai Péter</span> <span class="authorAux-mtmt"> Statisztika</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10086474"><a href="/gui2/?type=authors&mode=browse&sel=10086474" target="_blank">Engh Marie Anne (<span class="authorship-author-name">Engh Marie Anne</span> <span class="authorAux-mtmt"> Orvostudomány, egészségtudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10089630"><a href="/gui2/?type=authors&mode=browse&sel=10089630" target="_blank">Barna Viktória (<span class="authorship-author-name">Barna Viktória</span> <span class="authorAux-mtmt"> Dietetika és Táplálkozástudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002629"><a href="/gui2/?type=authors&mode=browse&sel=10002629" target="_blank">Hegyi Péter (<span class="authorship-author-name">Hegyi Péter</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Transzlációs Medicina Központ; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pankreász Betegségek Intézete</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Reis Henning </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013343"><a href="/gui2/?type=authors&mode=browse&sel=10013343" target="_blank">Nyirády Péter (<span class="authorship-author-name">Nyirády Péter</span> <span class="authorAux-mtmt"> Urológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Urológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10052466"><a href="/gui2/?type=authors&mode=browse&sel=10052466" target="_blank">Szarvas Tibor ✉ (<span class="authorship-author-name">Szarvas Tibor</span> <span class="authorAux-mtmt"> urológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Urológiai Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34801778" target="_blank">Estimation of the incidence of urachal cancer : A systematic review and meta-analysis of registry-based studies</a></div> <div> <span class="journal-title">UROLOGIC ONCOLOGY: SEMINARS AND ORIGINAL INVESTIGATIONS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1078-1439">1078-1439</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1873-2496">1873-2496</a>)</span>: <span class="journal-volume">42</span> <span class="journal-issue">7</span> <span class="page"> pp 221.e1-221.e7 </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1016/j.urolonc.2024.03.011" target="_blank" href="https://doi.org/10.1016/j.urolonc.2024.03.011"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001272964300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001272964300001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85190341786" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85190341786"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38627107" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38627107&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://www.scopus.com/pages/publications/85190341786?origin=resultslist" target="_blank" href="https://www.scopus.com/pages/publications/85190341786?origin=resultslist"> Egyéb URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Urology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Oncology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 13</span> | Független: 10 | Függő: 3 | Nem jelölt: 0 | WoS jelölt: 13 | Scopus jelölt:&nbsp;11 | WoS/Scopus jelölt:&nbsp;13 | DOI jelölt:&nbsp;13 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34801778&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 5 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34801778</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (BO/00451/20/5), (ÚNKP-21-5-SE-3), (K139059) </div> <div class="lastModified">Utolsó módosítás: 2026.06.18. 19:20 Milánkovics Róbert (PTE ÁOK admin 4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: Hungarian Academy of Sciences [BO/00451/20/5]; New National Excellence Program [UNKP-21-5-SE-3]; Ministry for Innovation and Technology from the source of the National Research Development and Innovation Fund [K139059] Funding text: T. S. was supported by a Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (BO/00451/20/5) and by ...</pre> </div></div>