https://m2.mtmt.hu/ eng 2026-04-15 21:27 JournalArticle 34775042 VALIDATED true Funding Agency and Grant Number: Hungarian National Research, Development and Innovation Office [FK 132251, ANN 139112, TKP2021-EGA-29]; Hungarian Academy of Sciences [LP2022-14/2022] Funding text: The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was funded and supported by the Hungarian National Research, Development and Innovation Office (No. FK 132251, No. ANN 139112 and TKP2021-EGA-29 to TN) and the Lendulet program (LP2022-14/2022) of the Hungarian Academy of Sciences (to TN). 0 false 2026-04-12T13:40:38.990+0000 2026-02-26T14:04:59.323+0000 2024-04-08T06:31:08.727+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2026-04-12T13:38:16.648+0000 2025-09-02T11:29:48.800+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Balogh, Lili Novel and potential future therapeutic options in systemic autoimmune diseases true true /api/journal/10023324 REVIEWED true false 10023324 false 10023324 true 1664-3224 1664-3224 Journal FOREIGN 15 1249500 1249500 16 2024 Autoimmune inflammation is caused by the loss of tolerance to specific self-antigens and can result in organ-specific or systemic disorders. Systemic autoimmune diseases affect a significant portion of the population with an increasing rate of incidence, which means that is essential to have effective therapies to control these chronic disorders. Unfortunately, several patients with systemic autoimmune diseases do not respond at all or just partially respond to available conventional synthetic disease-modifying antirheumatic drugs and targeted therapies. However, during the past few years, some new medications have been approved and can be used in real-life clinical settings. Meanwhile, several new candidates appeared and can offer promising novel treatment options in the future. Here, we summarize the newly available medications and the most encouraging drug candidates in the treatment of systemic lupus erythematosus, rheumatoid arthritis, Sjogren's disease, systemic sclerosis, systemic vasculitis, and autoimmune myositis. 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1126960 /api/keyword/1126960 true 1126960 true Keyword 1498634 /api/keyword/1498634 true true Keyword 3367939 /api/keyword/3367939 true true SjrRating 11472281 /api/sjrrating/11472281 37 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2403 /api/classificationexternal/2403 true 2403 true Q1 DIRECT true true /api/publication/34775042 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10088503"><a href="/gui2/?type=authors&mode=browse&sel=10088503" target="_blank">Balogh Lili (<span class="authorship-author-name">Balogh Lili</span> <span class="authorAux-mtmt"> Élettan</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Physiology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Internal Medicine and Oncology">DIMO</span>/<span title="Department of Rheumatology and Clinical Immunology">DRCI</span>/MTA-SE “Lendület” Translational Rheumatology Research Group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10095960"><a href="/gui2/?type=authors&mode=browse&sel=10095960" target="_blank">Olah Katalin (<span class="authorship-author-name">Oláh Katalin Fanni</span> <span class="authorAux-mtmt"> Reumatológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Physiology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Internal Medicine and Oncology">DIMO</span>/<span title="Department of Rheumatology and Clinical Immunology">DRCI</span>/MTA-SE “Lendület” Translational Rheumatology Research Group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Santa Soma </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10095210"><a href="/gui2/?type=authors&mode=browse&sel=10095210" target="_blank">Majerhoffer Nora (<span class="authorship-author-name">Majerhoffer Nóra</span> <span class="authorAux-mtmt"> transzlációs reumatológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Physiology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Internal Medicine and Oncology">DIMO</span>/<span title="Department of Rheumatology and Clinical Immunology">DRCI</span>/MTA-SE “Lendület” Translational Rheumatology Research Group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023794"><a href="/gui2/?type=authors&mode=browse&sel=10023794" target="_blank">Nemeth Tamas ✉ (<span class="authorship-author-name">Németh Tamás</span> <span class="authorAux-mtmt"> élettan</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Physiology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Internal Medicine and Oncology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Internal Medicine and Oncology">DIMO</span>/Department of Rheumatology and Clinical Immunology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Department of Internal Medicine and Oncology">DIMO</span>/<span title="Department of Rheumatology and Clinical Immunology">DRCI</span>/MTA-SE “Lendület” Translational Rheumatology Research Group</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34775042" target="_blank">Novel and potential future therapeutic options in systemic autoimmune diseases</a></div> <div> <span class="journal-title">FRONTIERS IN IMMUNOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1664-3224">1664-3224</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1664-3224">1664-3224</a>)</span>: <span class="journal-volume">15</span> <span class="page"> Paper 1249500. 16 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3389/fimmu.2024.1249500" target="_blank" href="https://doi.org/10.3389/fimmu.2024.1249500"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001193113200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001193113200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85189164398" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85189164398"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38558805" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38558805&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_NONE" title=" None "> <a style="color:blue" title="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189164398&doi=10.3389%2ffimmu.2024.1249500&partnerID=40&md5=80c22d71628730c108094d7fecb5020a" target="_blank" href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189164398&doi=10.3389%2ffimmu.2024.1249500&partnerID=40&md5=80c22d71628730c108094d7fecb5020a"> Other URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Immunology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Immunology and Allergy&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 19</span> | Independent citation: 18 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 17 | Number of citations in Scopus:&nbsp;15 | WoS/Scopus assigned:&nbsp;19 | Number of citations with DOI:&nbsp;19 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34775042&sort=publishedYear,desc&sort=title"> Number of cited publications: 8 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 34775042</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="funder"> (FK132251), (ANN139112), (TKP2021-EGA-29), (LP2022-14/2022) </div> <div class="lastModified">Last Modified: 2026.02.26. 15:04 Gizella Áncsán (SE admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Funding Agency and Grant Number: Hungarian National Research, Development and Innovation Office [FK 132251, ANN 139112, TKP2021-EGA-29]; Hungarian Academy of Sciences [LP2022-14/2022] Funding text: The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was funded and supported by the Hungarian National Researc...</pre> </div></div>