https://m2.mtmt.hu/ hun 2026-09-21 00:27 JournalArticle 34744209 VALIDATED true Funding Agency and Grant Number: Hungarian Scientific Research Fund; National Research, Development and Innovation Office [TKP2021-EGA-31, RRF-2.3.1-21-2022-00015]; European Union; [OTKA ANN 139484]; [OTKA 139216] Funding text: We are grateful to the Hungarian Scientific Research Fund (OTKA ANN 139484, OTKA 139216). The financial support of the National Research, Development and Innovation Office (TKP2021-EGA-31) is acknowledged. Project no. RRF-2.3.1-21-2022-00015 has been implemented with the support provided by the European Union. 0 false 2026-06-30T11:47:12.762+0000 2026-06-30T11:44:10.585+0000 2024-03-18T17:04:50.717+0000 true 10079694 Lázárné Zalán Zita /api/admin/10079694 Admin Lázárné Zalán Zita (SZTE admin5 GYTK Gyógyszerkémiai Intézet) true 2026-06-30T11:44:10.446+0000 2024-06-05T03:14:15.885+0000 true 521 Szuper Admin /api/admin/521 Admin Szuper Admin (admin) true Admin 10065569 /api/admin/10065569 Pécsi Éva (MTMT Közp 2,3, admin) Pécsi Éva true true 2026-04-14T13:01:34.757+0000 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Piros, L. true true /api/journal/10062814 REVIEWED CHEMISTRYSELECT 2365-6549 2365-6549 true false 10062814 false 10062814 true 2365-6549 2365-6549 Journal FOREIGN 9 10 e202304969 e202304969 6 2024 Comparative synthesis of some new quinazoline derivatives via tetrakis(triphenylphosphine)palladium(0) catalysed Suzuki-Miyaura cross-coupling reaction in “green” propylene carbonate (PC) and dimethoxyethane. Three haloquinazolines were synthesised for Suzuki-cross-coupling from 5-bromoanthranilic acid. Sufficient and easy method for the elimination of PC is developed, thus the optimization of the synthesis of some quinazoline derivatives was carried out. Reactions with 2-chloro-6-bromo-3-phenylquinazolin-4(3H)-one proceeded faster and with a higher yield in PC than in dimethoxyethane, thus for some reactants PC is a good choice for greener synthesis. Practical considerations for using PC include shorter reaction times, improved yields, and the elimination of unnecessary solvent distillation, leading to significant energy savings. This facilitates the execution of energy-efficient reactions in a notably environmentally friendly solvent. In contrast to DME, the use of PC does not necessitate special pre-treatments. Moreover, less PC is required due to its high boiling point and low volatility. Considering these properties, coupled with the consistent need for chromatographic purification, the use of PC in the Suzuki-Miyaura cross-coupling reaction emerges as a superior and greener alternative compared to DME. © 2024 The Authors. ChemistrySelect published by Wiley-VCH GmbH. Funding 2038219 /api/funding/2038219 (ANN139484) false true Funding 2038220 /api/funding/2038220 OTKA(139216) Támogató: NKFIH false true Funding 2038221 /api/funding/2038221 (TKP2021-EGA-31) false true Funding 2038222 /api/funding/2038222 Nemzeti Gyógyszerkutatási és Fejlesztési Laboratórium (PharmaLab)(RRF-2.3.1-21-2022-00015) Támogató: NKFIH false true true 2024 true true true false true false NONE 2026-06-30 false 3 0 3 2 1 3 3 3 3 3 3 2 2 2 1 0 3 2 3 2 0 7 7 Folyóiratcikk Journal Article 24 3 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 1 1 1 1 2025 0 1 0 1 0 2026 0 1 1 1 1 Q3 false 10022276 false false false 2024-03-17T17:07:07.249+0000 Anyag- és Környezetkémiai Intézet (HRN TTK); Gyógyszerészi Kémiai Intézet (SE / GYTK); Mesterséges Transzporterek Kutatócsoport (HRN TTK / AKI); Szerves Vegytani Intézet (SE / GYTK) 6 32 4 7 0 true 10065569 Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 115844395 /api/authorship/115844395 Piros, L. [Piros, László (szerves kémia), szerző] Szerves Vegytani Intézet (SE / GYTK) 1 0.143 true false false Author 10094645 /api/author/10094645 Piros László (szerves kémia) Piros László true true Piros L. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 115844396 /api/authorship/115844396 Krajsovszky, G. [Krajsovszky, Gábor (Szerves-és gyógys...), szerző] Szerves Vegytani Intézet (SE / GYTK) 2 0.143 false false false Author 10022276 /api/author/10022276 Krajsovszky Gábor (Szerves-és gyógyszerkémia) Krajsovszky Gábor DUPLUM true 10022276 true Krajsovszky G. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 115844397 /api/authorship/115844397 Bogdán, D. [Bogdán, Dóra (Szerves kémia, gy...), szerző] Szerves Vegytani Intézet (SE / GYTK); Mesterséges Transzporterek Kutatócsoport (HRN TTK / AKI); Anyag- és Környezetkémiai Intézet (HRN TTK) 3 0.143 false false false Author 10049468 /api/author/10049468 Bogdán Dóra (Szerves kémia, gyógyszerkémia) Bogdán Dóra true 10049468 true Bogdán D. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 115844398 /api/authorship/115844398 Gáti, T. 4 0.14285715 false false false Gáti T. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 115844399 /api/authorship/115844399 Szabó, P. [Szabó, Pál Tamás (Tömegspektrometria), szerző] 5 0.14285715 false false false Author 10014589 /api/author/10014589 Szabó Pál Tamás (Tömegspektrometria) Szabó Pál Tamás true 10014589 true Szabó P. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 115844400 /api/authorship/115844400 Horváth, P. [Horváth, Péter (cirkuláris dikroi...), szerző] Gyógyszerészi Kémiai Intézet (SE / GYTK) 6 0.143 false false false Author 10020177 /api/author/10020177 Horváth Péter (cirkuláris dikroizmus, HPLC) Horváth Péter true 10020177 true Horváth P. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 115844401 /api/authorship/115844401 Mándity, I.M. ✉ [Mándity, István (Gyógyszerkémia, g...), szerző] Szerves Vegytani Intézet (SE / GYTK); Mesterséges Transzporterek Kutatócsoport (HRN TTK / AKI) 7 0.143 false true true Author 10022837 /api/author/10022837 Mándity István (Gyógyszerkémia, gyógyszerkutatás) Mándity István true 10022837 true Mándity I.M. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 25881731 /api/publicationidentifier/25881731 DOI: 10.1002/slct.202304969 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1002/slct.202304969 https://doi.org/10.1002/slct.202304969 false true PublicationIdentifier 25938406 /api/publicationidentifier/25938406 WoS: 001179655500001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001179655500001 https://www.webofscience.com/wos/woscc/full-record/001179655500001 false true PublicationIdentifier 25881730 /api/publicationidentifier/25881730 Scopus: 85187146212 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85187146212 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85187146212 false true Classification 10001 /api/classification/10001 Tudomány true true Keyword 3172 /api/keyword/3172 PALLADIUM true 3172 true Keyword 1001036 /api/keyword/1001036 cross-coupling true 1001036 true Keyword 1155094 /api/keyword/1155094 QUINAZOLINE true 1155094 true Keyword 3363219 /api/keyword/3363219 Green chemistry, Propylene carbonate true true SjrRating 11447979 /api/sjrrating/11447979 sjr:Q3 (2024) Scopus - Chemistry (miscellaneous) CHEMISTRYSELECT 2365-6549 2365-6549 286 0.74 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1601 /api/classificationexternal/1601 Scopus - Chemistry (miscellaneous) true 1601 true Q3 DIRECT true true Reference 51172854 /api/reference/51172854 1. 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(2024) CHEMISTRYSELECT 2365-6549 2365-6549 9 10<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10094645"><a href="/gui2/?type=authors&mode=browse&sel=10094645" target="_blank">Piros L. (<span class="authorship-author-name">Piros László</span> <span class="authorAux-mtmt"> szerves kémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10022276"><a href="/gui2/?type=authors&mode=browse&sel=10022276" target="_blank">Krajsovszky G. (<span class="authorship-author-name">Krajsovszky Gábor</span> <span class="authorAux-mtmt"> Szerves-és gyógyszerkémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10049468"><a href="/gui2/?type=authors&mode=browse&sel=10049468" target="_blank">Bogdán D. (<span class="authorship-author-name">Bogdán Dóra</span> <span class="authorAux-mtmt"> Szerves kémia, gyógyszerkémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet; <span title="HUN-REN Természettudományi Kutatóközpont">HRN TTK</span>/<span title="Anyag- és Környezetkémiai Intézet">AKI</span>/Mesterséges Transzporterek Kutatócsoport; <span title="HUN-REN Természettudományi Kutatóközpont">HRN TTK</span>/Anyag- és Környezetkémiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gáti T. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10014589"><a href="/gui2/?type=authors&mode=browse&sel=10014589" target="_blank">Szabó P. (<span class="authorship-author-name">Szabó Pál Tamás</span> <span class="authorAux-mtmt"> Tömegspektrometria</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10020177"><a href="/gui2/?type=authors&mode=browse&sel=10020177" target="_blank">Horváth P. (<span class="authorship-author-name">Horváth Péter</span> <span class="authorAux-mtmt"> cirkuláris dikroizmus, HPLC</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Gyógyszerészi Kémiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10022837"><a href="/gui2/?type=authors&mode=browse&sel=10022837" target="_blank">Mándity I.M. ✉ (<span class="authorship-author-name">Mándity István</span> <span class="authorAux-mtmt"> Gyógyszerkémia, gyógyszerkutatás</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet; <span title="HUN-REN Természettudományi Kutatóközpont">HRN TTK</span>/<span title="Anyag- és Környezetkémiai Intézet">AKI</span>/Mesterséges Transzporterek Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34744209" target="_blank">Energy-Efficient Synthesis of Haloquinazolines and Their Suzuki Cross-Coupling Reactions in Propylene Carbonate</a></div> <div> <span class="journal-title">CHEMISTRYSELECT</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2365-6549">2365-6549</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2365-6549">2365-6549</a>)</span>: <span class="journal-volume">9</span> <span class="journal-issue">10</span> <span class="page"> Paper e202304969. 6 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1002/slct.202304969" target="_blank" href="https://doi.org/10.1002/slct.202304969"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001179655500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001179655500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85187146212" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85187146212"> Scopus </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Chemistry (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 3</span> | Független: 2 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 3 | Scopus jelölt:&nbsp;3 | WoS/Scopus jelölt:&nbsp;3 | DOI jelölt:&nbsp;3 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34744209&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 7 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34744209</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="funder"> (ANN139484), OTKA(139216) Támogató: NKFIH, (TKP2021-EGA-31), Nemzeti Gyógyszerkutatási és Fejlesztési Laboratórium (PharmaLab)(RRF-2.3.1-21-2022-00015) Támogató: NKFIH </div> <div class="lastModified">Utolsó módosítás: 2026.06.30. 13:44 Nemec Évi (MTMT Központi 3, admin) </div> <div class="lockedBy">Központi kezelésű 2026.04.14. 15:01 Pécsi Éva (MTMT Közp 2,3, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: Hungarian Scientific Research Fund; National Research, Development and Innovation Office [TKP2021-EGA-31, RRF-2.3.1-21-2022-00015]; European Union; [OTKA ANN 139484]; [OTKA 139216] Funding text: We are grateful to the Hungarian Scientific Research Fund (OTKA ANN 139484, OTKA 139216). The financial support of the National Research, Development and I...</pre> </div></div>