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      <abstractText>To investigate the rate of residual disease in the Potsic staging system for congenital cholesteatomas.A protocol registration was published on PROSPERO (CRD42022383932), describing residual disease as a primary outcome and hearing improvement as secondary. A systematic search was performed in four databases (PubMed, Embase, Cochrane Library, Web of Science) on December 14, 2022. Articles were included if cholesteatomas were staged according to the Potsic system and follow-up duration was documented. Risk of bias was evaluated using the Quality In Prognosis Studies (QUIPS) tool. In the statistical synthesis a random effects model was used. Between-study heterogeneity was assessed using I2.Thirteen articles were found to be eligible for systematic review and seven were included in the meta-analysis section. All records were retrospective cohort studies with high risk of bias. Regarding the proportions of residual disease, analysis using the χ2 test showed no statistically significant difference between Potsic stages after a follow-up of minimum one year (stage I 0.06 (confidence interval (CI) 0.01-0.33); stage II 0.20 (CI 0.09-0.38); stage III 0.06 (CI 0.00-0.61); stage IV: 0.17 (CI 0.01-0.81)). Postoperative and preoperative hearing outcomes could not be analyzed due to varied reporting. Results on cholesteatoma location and mean age at staging were consistent with those previously published.No statistically significant difference was found in the proportions of residual disease between Potsic stages, thus the staging system's applicability for outcome prediction could not be proven based on the available data. Targeted studies are needed for a higher level of evidence.</abstractText>
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Dietetika&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Hungarian University of Sports Science&quot;&gt;HUSS&lt;/span&gt;/&lt;span title=&quot;Sport- és Egészségtudományi Intézet&quot;&gt;SETI&lt;/span&gt;/Sport-táplálkozástudományi Központ; &lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Centre for Translational Medicine; &lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Faculty of Health Sciences&quot;&gt;FHS&lt;/span&gt;/Department of Morphology and Physiology&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10086439&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10086439&quot; target=&quot;_blank&quot;&gt;Shulze Wenning Alexander (&lt;span class=&quot;authorship-author-name&quot;&gt;Schulze Wenning Alexander&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Orvostudomány, egészségtudomány&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Centre for Translational Medicine&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10023284&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10023284&quot; target=&quot;_blank&quot;&gt;Fehérvári Péter (&lt;span class=&quot;authorship-author-name&quot;&gt;Fehérvári Péter&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Biomatematika&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Centre for Translational Medicine; &lt;span title=&quot;University of Veterinary Medicine Budapest&quot;&gt;UVMB&lt;/span&gt;/&lt;span title=&quot;Élelmiszerlánc-biztonsági és Járványvédelmi Intézet&quot;&gt;ÉBJI&lt;/span&gt;/&lt;span title=&quot;Institute of Economics and Biostatistics&quot;&gt;IEB&lt;/span&gt;/Department of Biostatistics&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10002007&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10002007&quot; target=&quot;_blank&quot;&gt;Harnos Andrea (&lt;span class=&quot;authorship-author-name&quot;&gt;Harnos Andrea&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Biostatisztika&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Centre for Translational Medicine&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10002629&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10002629&quot; target=&quot;_blank&quot;&gt;Hegyi Péter (&lt;span class=&quot;authorship-author-name&quot;&gt;Hegyi Péter&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Gasztroenterológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Centre for Translational Medicine; &lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Faculty of Medicine&quot;&gt;FM&lt;/span&gt;/&lt;span title=&quot;Clinical&quot;&gt;C&lt;/span&gt;/Institute of Pancreatic Diseases&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10001298&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10001298&quot; target=&quot;_blank&quot;&gt;Molnár Zsolt (&lt;span class=&quot;authorship-author-name&quot;&gt;Molnár Zsolt&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Klinikai orvostudományok - aneszteziológia és i...&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Faculty of Medicine&quot;&gt;FM&lt;/span&gt;/&lt;span title=&quot;Clinical&quot;&gt;C&lt;/span&gt;/Department of Anesthesoiology and Intensiv Therapy; &lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Centre for Translational Medicine&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10085429&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10085429&quot; target=&quot;_blank&quot;&gt;Illés Kata (&lt;span class=&quot;authorship-author-name&quot;&gt;Illés Kata&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Fül- Orr-Gégészet&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Centre for Translational Medicine&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10064479&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10064479&quot; target=&quot;_blank&quot;&gt;Horváth Tamás ✉ (&lt;span class=&quot;authorship-author-name&quot;&gt;Horváth Tamás&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Fül- orr- gégészet&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis University&quot;&gt;SU&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Centre for Translational Medicine&lt;/span&gt; &lt;/div&gt; &lt;/div&gt; &lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;34619431&quot; target=&quot;_blank&quot;&gt;Predicting residual cholesteatoma with the Potsic staging system still lacks evidence: a systematic review and meta-analysis&lt;/a&gt;&lt;/div&gt; &lt;div&gt; &lt;span class=&quot;journal-title&quot;&gt;EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY&lt;/span&gt; &lt;span class=&quot;journal-issn&quot;&gt;(&lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/0937-4477&quot;&gt;0937-4477&lt;/a&gt; &lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/1434-4726&quot;&gt;1434-4726&lt;/a&gt;)&lt;/span&gt;: &lt;span class=&quot;journal-volume&quot;&gt;281&lt;/span&gt; &lt;span class=&quot;journal-issue&quot;&gt;7&lt;/span&gt; &lt;span class=&quot;page&quot;&gt; pp 3557-3568 &lt;/span&gt; &lt;span class=&quot;year&quot;&gt;(2024)&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;pub-footer&quot;&gt;  &lt;span class=&quot;language&quot; xmlns=&quot;http://www.w3.org/1999/html&quot;&gt;Language: English | &lt;/span&gt; &lt;span class=&quot;identifiers&quot;&gt; &lt;span class=&quot;id identifier oa_GOLD&quot; title=&quot; Gold &quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;10.1007/s00405-024-08478-3&quot; target=&quot;_blank&quot; href=&quot;https://doi.org/10.1007/s00405-024-08478-3&quot;&gt; DOI &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;001160351200001&quot; target=&quot;_blank&quot; href=&quot;https://www.webofscience.com/wos/woscc/full-record/001160351200001&quot;&gt; WoS &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;85185131770&quot; target=&quot;_blank&quot; href=&quot;http://www.scopus.com/record/display.url?origin=inward&amp;eid=2-s2.0-85185131770&quot;&gt; Scopus &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;38351408&quot; target=&quot;_blank&quot; href=&quot;http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=38351408&amp;dopt=Abstract&quot;&gt; PubMed &lt;/a&gt; &lt;/span&gt; &lt;/span&gt; &lt;OnlyViewableByAuthor&gt;&lt;div class=&quot;ratings&quot;&gt; &lt;div class=&quot;journal-subject&quot;&gt;Journal subject: Scopus - Otorhinolaryngology&amp;nbsp;&amp;nbsp;&amp;nbsp;Rank:&amp;nbsp;Q1&lt;/div&gt; &lt;div class=&quot;journal-subject&quot;&gt;Journal subject: Scopus - Medicine (miscellaneous)&amp;nbsp;&amp;nbsp;&amp;nbsp;Rank:&amp;nbsp;Q2&lt;/div&gt; &lt;/div&gt;&lt;/OnlyViewableByAuthor&gt; &lt;div class=&quot;publication-citation&quot; style=&quot;margin-left: 0.5cm;&quot;&gt; &lt;span title=&quot;&quot; class=&quot;citingPub-count&quot;&gt;Citing papers: 5&lt;/span&gt; | Independent citation: 5 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 2 | Number of citations in Scopus:&amp;nbsp;3 | WoS/Scopus assigned:&amp;nbsp;3 | Number of citations with DOI:&amp;nbsp;4 &lt;/div&gt;   &lt;div class=&quot;publication-citation&quot;&gt; &lt;a target=&quot;_blank&quot; href=&quot;/api/publication?cond=citations.related;eq;34619431&amp;sort=publishedYear,desc&amp;sort=title&quot;&gt; Number of cited publications: 1 &lt;/a&gt; &lt;/div&gt; &lt;div class=&quot;mtid&quot;&gt;&lt;span class=&quot;long-pub-mtid&quot;&gt;Publication: 34619431&lt;/span&gt; | &lt;span class=&quot;status-data status-VALIDATED&quot;&gt; Validated &lt;/span&gt; Core Citing | &lt;span class=&quot;type-subtype&quot;&gt;Journal Article ( Survey paper ) &lt;/span&gt; | &lt;span class=&quot;pub-category&quot;&gt;Scientific&lt;/span&gt; | &lt;span class=&quot;publication-sourceOfData&quot;&gt;kézi felvitel&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;funder&quot;&gt; (Open access funding provided by Semmelweis University) &lt;/div&gt; &lt;div class=&quot;lastModified&quot;&gt;Last Modified: 2026.06.05. 11:01 Tamásné Gere (SE_KK_Admin5_GT, admin) &lt;/div&gt; &lt;/div&gt;&lt;/div&gt;</template2>
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