https://m2.mtmt.hu/ hun 2026-10-25 08:05 JournalArticle 34544359 VALIDATED true 0 false 2026-10-24T05:21:41.922+0000 2024-02-27T08:08:45.673+0000 2024-01-30T12:05:09.596+0000 true 10070075 Nádas Orsolya /api/admin/10070075 Admin true 2024-10-09T12:40:06.034+0000 2024-02-12T14:09:53.173+0000 true 10065569 Pécsi Éva /api/admin/10065569 Admin true 2024-02-16T00:58:37.650+0000 true 521 Szuper Admin /api/admin/521 Admin true Admin 10065569 /api/admin/10065569 Pécsi Éva true true 2026-02-06T10:56:21.970+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Gesztesi, László Alterations of Sexual and Erectile Functions after Brachytherapy for Prostate Cancer Based on Patient-Reported Questionnaires true true /api/journal/10063151 REVIEWED true false 10063151 false 10063151 true 2090-3111 2090-312X Journal FOREIGN 2024 5729185 5729185 13 2024 The aim of the study was to compare the side effects of high-dose-rate brachytherapy (HDRBT) and low-dose-rate brachytherapy (LDRBT), with a particular focus on the effects on sexual functions and sexual well-being (PROMOBRA study, NCT02258087). Localized low-risk and low-intermediate-risk prostate cancer patients were treated with mono LDR (N = 123, 145 Gy dose) or mono HDR brachytherapy (N = 117, 19/21 Gy). Prior to the treatment and during follow-up (at 3, 6, 9, 12, 18, and 24 months after treatment, and then annually after two years), patients completed patient-reported outcome measurement (PROM) questionnaires EORTC QLQ-PR-25, International Index of Erectile Function (IIEF), and IIEF-5 (SHIM). We compared the patients in different group breakdowns (HDR vs. LDR, hormone naïve and hormone-receiving HDR vs. LDR, hormone naïve and hormone-receiving patients in general, and 19 Gy HDR vs. 21 Gy HDR). In the hormone-naive LDR group, erectile function, orgasm function, sexual desire, satisfaction with intercourse, and overall satisfaction functions significantly decreased compared to baseline throughout the whole follow-up period. However, there were significant decreases in function at a maximum of three time points after HDR therapy without hormone therapy. In hormone-receiving patients, the orgasm function was significantly better in the HDR group at multiple time points compared to the baseline, and sexual desire improved at four time points. According to our results, both LDRBT and HDRBT can be safely administered to patients with localized prostate cancer. In hormone-naive patients, the HDR group showed only recovering decreases in sexual functions, while the LDR group showed a lasting decline in multiple areas. Thus, HDR appears to be more advantageous to hormone-naive patients. 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2024-02-11T14:09:52.710+0000 Onkológiai Tanszék (SE / AOK / K); Országos Onkológiai Intézet 6 20 2 6 0 true 10065569 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 114150853 /api/authorship/114150853 1 0.167 true false false Author 10058289 /api/author/10058289 Gesztesi László true 10058289 true Gesztesi László true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 114150854 /api/authorship/114150854 2 0.167 false false false Author 10020433 /api/author/10020433 Kocsis Zsuzsa true 10020433 true Kocsis Zsuzsa S. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 114150855 /api/authorship/114150855 3 0.167 false false false Author 10064469 /api/author/10064469 Jorgo Kliton true 10064469 true Jorgo Kliton true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 114150856 /api/authorship/114150856 4 0.167 false false false Author 10016868 /api/author/10016868 Fröhlich Georgina true 10016868 true Fröhlich Georgina true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 114150857 /api/authorship/114150857 5 0.167 false false false Author 10013383 /api/author/10013383 Polgár Csaba true 10013383 true Polgár Csaba true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 114150858 /api/authorship/114150858 6 0.167 false true true Author 10030572 /api/author/10030572 Ágoston Péter Zoltán true 10030572 true Ágoston Péter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 25389541 /api/publicationidentifier/25389541 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1155/2024/5729185 https://doi.org/10.1155/2024/5729185 false true PublicationIdentifier 25526729 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<img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10058289"><a href="/gui2/?type=authors&mode=browse&sel=10058289" target="_blank">Gesztesi László (<span class="authorship-author-name">Gesztesi László</span> <span class="authorAux-mtmt"> Sugárterápia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10020433"><a href="/gui2/?type=authors&mode=browse&sel=10020433" target="_blank">Kocsis Zsuzsa S. (<span class="authorship-author-name">Kocsis Zsuzsa</span> <span class="authorAux-mtmt"> sugárbiológia, onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10064469"><a href="/gui2/?type=authors&mode=browse&sel=10064469" target="_blank">Jorgo Kliton (<span class="authorship-author-name">Jorgo Kliton</span> <span class="authorAux-mtmt"> Onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016868"><a href="/gui2/?type=authors&mode=browse&sel=10016868" target="_blank">Fröhlich Georgina (<span class="authorship-author-name">Fröhlich Georgina</span> <span class="authorAux-mtmt"> Sugárfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013383"><a href="/gui2/?type=authors&mode=browse&sel=10013383" target="_blank">Polgár Csaba (<span class="authorship-author-name">Polgár Csaba</span> <span class="authorAux-mtmt"> Sugárterápia, klinikai onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10030572"><a href="/gui2/?type=authors&mode=browse&sel=10030572" target="_blank">Ágoston Péter ✉ (<span class="authorship-author-name">Ágoston Péter Zoltán</span> <span class="authorAux-mtmt"> Sugárterápia, onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34544359" target="_blank">Alterations of Sexual and Erectile Functions after Brachytherapy for Prostate Cancer Based on Patient-Reported Questionnaires</a></div> <div> <span class="journal-title">PROSTATE CANCER</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2090-3111">2090-3111</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2090-312X">2090-312X</a>)</span>: <span class="journal-volume">2024</span> <span class="page"> Paper 5729185. 13 p. </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1155/2024/5729185" target="_blank" href="https://doi.org/10.1155/2024/5729185"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001155611300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001155611300001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85184899150" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85184899150"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="38312318" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38312318&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="https://www.hindawi.com/journals/pc/2024/5729185/" target="_blank" href="https://www.hindawi.com/journals/pc/2024/5729185/"> Egyéb URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Urology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Cancer Research&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Oncology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | WoS/Scopus jelölt:&nbsp;1 | DOI jelölt:&nbsp;1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34544359&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34544359</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (National Tumor Biology Laboratory project—2022-2.1.1-NL-2022-00010), Hungarian Thematic Excellence Program((TKP2021-EGA-44)), (2020-1.1.6-JÖVŐ-2021-00008) </div> <div class="lastModified">Utolsó módosítás: 2024.02.27. 09:08 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <div class="lockedBy">Központi kezelésű 2026.02.06. 11:56 Pécsi Éva (MTMT Közp 2,3, admin) </div> </div></div>