The lemur family of protein kinases has gained much interest in recent years as they
are involved in a variety of cellular processes including regulation of axonal transport
and endosomal trafficking, modulation of synaptic functions, memory and learning,
and they are centrally placed in several intracellular signalling pathways. Numerous
studies have also implicated role of the lemur kinases in the development and progression
of a wide range of cancers, cystic fibrosis, and neurodegenerative diseases. However,
parallel discoveries and inaccurate prediction of their kinase activity have resulted
in a confusing and misleading nomenclature of these proteins. Herein, a group of international
scientists with expertise in lemur family of protein kinases set forth a novel nomenclature
to rectify this problem and ultimately help the scientific community by providing
consistent information about these molecules.
