https://m2.mtmt.hu/ hun 2026-09-22 21:36 JournalArticle 34484703 VALIDATED true Export Date: 30 March 2025; CODEN: CGHLA 0 false 2026-09-05T14:02:55.211+0000 2025-03-27T10:18:38.941+0000 2024-01-08T14:12:44.550+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 2026-08-03T08:56:19.203+0000 2025-03-27T10:18:39.060+0000 true 10015546 Berhidi Anna /api/admin/10015546 Admin true 10015546 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType 104 true 10000359 true 1 /api/category/1 Category true 1 Overbeek, Kasper A Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment true true /api/journal/10006933 REVIEWED true false 10006933 false 10006933 true 1542-3565 1542-7714 Journal FOREIGN 22 5 994 1004.e10 994 21 2024 Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology and manifestations. Our aims were to characterize type 1 AIP in a large pan-European cohort and study the effectiveness of current treatment regimens.We retrospectively analyzed adults diagnosed since 2005 with type 1 or not-otherwise-specified AIP in 42 European university hospitals. Type 1 AIP was uniformly diagnosed using specific diagnostic criteria. Patients with type 2 AIP and those who had undergone pancreatic surgery were excluded. The primary endpoint was complete remission, defined as the absence of clinical symptoms and resolution of the index radiological pancreatic abnormalities attributed to AIP.We included 735 individuals with AIP (69% male; median age 57 years; 85% White). Steroid treatment was started in 634 patients, of whom 9 (1%) were lost to follow-up. The remaining 625 had a 79% (496/625) complete, 18% (111/625) partial, and 97% (607/625) cumulative remission rate, while 3% (18/625) did not achieve remission. No treatment was given in 95 patients, who had a 61% complete (58/95), 19% partial (18/95), and 80% cumulative (76/95) spontaneous remission rate. Higher (≥0.4 mg/kg/day) corticosteroid doses were no more effective than lower (<0.4 mg/kg/day) doses (OR 0.428; 95%CI 0.054-3.387) and neither was a starting dose duration > 2 weeks (OR 0.908; 95%CI 0.818-1.009). Elevated IgG4 levels were independently associated with a decreased chance of complete remission (OR 0.639; 95%CI 0.427-0.955). Relapse occurred in 30% of patients. Relapses within 6 months of remission induction were independent of the steroid tapering duration, induction treatment duration, and total cumulative dose.Patients with type 1 AIP and elevated IgG4 level may need closer monitoring. For remission induction, a starting dose of 0.4 mg/kg/day for 2 weeks followed by a short taper period seems effective. 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false false false 2024-04-08T05:52:46.398+0000 Pankreász Betegségek Részlege (SE / AOK / K); Szentágothai János Kutatóközpont (PTE); Transzlációs Medicina Intézet (PTE / ÁOK); Transzlációs medicina kutatócsoport (PTE / SZKK) 2 27 4 65 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 113704974 /api/authorship/113704974 1 0.0 true false true Overbeek Kasper A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704975 /api/authorship/113704975 2 0.0 false false false Poulsen Jakob L true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704976 /api/authorship/113704976 3 0.0 false false false Lanzillotta Marco true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704977 /api/authorship/113704977 4 0.0 false false false Vinge-Holmquist Olof true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704978 /api/authorship/113704978 5 0.0 false false false Macinga Peter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704979 /api/authorship/113704979 6 0.0 false false false Demirci A Fatih true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704980 /api/authorship/113704980 7 0.0 false false false Sindhunata Daniko P true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704981 /api/authorship/113704981 8 0.0 false false false Backhus Johanna true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704982 /api/authorship/113704982 9 0.0 false false false Algül Hana true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704983 /api/authorship/113704983 10 0.0 false false false Buijs Jorie true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704984 /api/authorship/113704984 11 0.0 false false false Levy Philippe true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704985 /api/authorship/113704985 12 0.0 false false false Kiriukova Mariia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704986 /api/authorship/113704986 13 0.0 false false false Goni Elisabetta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704987 /api/authorship/113704987 14 0.0 false false false Hollenbach Marcus true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704988 /api/authorship/113704988 15 0.0 false false false Miksch Rainer C true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704989 /api/authorship/113704989 16 0.0 false false false Kunovsky Lumir true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704990 /api/authorship/113704990 17 0.0 false false false Vujasinovic Miroslav true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704991 /api/authorship/113704991 18 0.0 false false false Nikolic Sara true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704992 /api/authorship/113704992 19 0.0 false false false Dickerson Luke true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704993 /api/authorship/113704993 20 0.0 false false false Hirth Michael true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704994 /api/authorship/113704994 21 0.0 false false false Neurath Markus F true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704995 /api/authorship/113704995 22 0.0 false false false Zumblick Malte true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704996 /api/authorship/113704996 23 0.0 false false false Vila Josephine true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704997 /api/authorship/113704997 24 0.0 false false false Jalal Mustafa true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704998 /api/authorship/113704998 25 0.0 false false false Beyer Georg true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113704999 /api/authorship/113704999 26 0.0 false false false Frost Fabian true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705000 /api/authorship/113705000 27 0.0 false false false Carrara Silvia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true 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AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705007 /api/authorship/113705007 34 0.0 false false false Arlt Alexander true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705008 /api/authorship/113705008 35 0.0 false false false Vleggaar Frank P true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705009 /api/authorship/113705009 36 0.0 false false false Barresi Luca true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705010 /api/authorship/113705010 37 0.0 false false false Greenhalf Bill true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705011 /api/authorship/113705011 38 0.0 false false false Author 10000322 /api/author/10000322 Czakó László true 10000322 true Czakó László true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705012 /api/authorship/113705012 39 0.0 false false false Author 10002629 /api/author/10002629 Hegyi Péter true 10002629 true Hegyi Peter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705013 /api/authorship/113705013 40 0.0 false false false Hopper Andrew true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705014 /api/authorship/113705014 41 0.0 false false false Nayar Manu K true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705015 /api/authorship/113705015 42 0.0 false false false Gress Thomas M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705016 /api/authorship/113705016 43 0.0 false false false Vitali Francesco true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705017 /api/authorship/113705017 44 0.0 false false false Schneider Alexander true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705018 /api/authorship/113705018 45 0.0 false false false Halloran Chris M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705019 /api/authorship/113705019 46 0.0 false false false Trna Jan true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705020 /api/authorship/113705020 47 0.0 false false false Okhlobystin Alexey V true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705021 /api/authorship/113705021 48 0.0 false false false Dagna Lorenzo true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705022 /api/authorship/113705022 49 0.0 false false false Cahen Djuna L true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705023 /api/authorship/113705023 50 0.0 false false false Bordin Dmitry true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705024 /api/authorship/113705024 51 0.0 false false false Rebours Vinciane true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705025 /api/authorship/113705025 52 0.0 false false false Mayerle Julia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705026 /api/authorship/113705026 53 0.0 false false false Kahraman Alisan true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705027 /api/authorship/113705027 54 0.0 false false false Rasch Sebastian true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705028 /api/authorship/113705028 55 0.0 false false false Culver Emma true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705029 /api/authorship/113705029 56 0.0 false false false Kleger Alexander true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705030 /api/authorship/113705030 57 0.0 false false false Martínez-Moneo Emma true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705031 /api/authorship/113705031 58 0.0 false false false Røkke Ola true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705032 /api/authorship/113705032 59 0.0 false false false Hucl Tomas true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705033 /api/authorship/113705033 60 0.0 false false false Olesen Søren S true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705034 /api/authorship/113705034 61 0.0 false false false Bruno Marco J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705035 /api/authorship/113705035 62 0.0 false false false Della-Torre Emanuel true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705036 /api/authorship/113705036 63 0.0 false false false Beuers Ulrich true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705037 /api/authorship/113705037 64 0.0 false false false Lo Hr J-Matthias true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113705038 /api/authorship/113705038 65 0.0 false true true Rosendahl Jonas true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true OrgAuthorship 113705039 /api/authorship/113705039 66 0.0 false false false true false false AuthorshipType 30 /api/authorshiptype/30 -29 true -29 true false true PublicationIdentifier 25247919 /api/publicationidentifier/25247919 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1016/j.cgh.2023.12.010 https://doi.org/10.1016/j.cgh.2023.12.010 false true PublicationIdentifier 26718155 /api/publicationidentifier/26718155 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001241830900001 https://www.webofscience.com/wos/woscc/full-record/001241830900001 false true PublicationIdentifier 25605725 /api/publicationidentifier/25605725 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85184766789 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85184766789 false true PublicationIdentifier 25247918 /api/publicationidentifier/25247918 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38184096 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38184096&dopt=Abstract false true Classification 12302 /api/classification/12302 true true Keyword 1187179 /api/keyword/1187179 true 1187179 true Keyword 1512096 /api/keyword/1512096 true true Keyword 2330720 /api/keyword/2330720 true true SjrRating 11465565 /api/sjrrating/11465565 7 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2715 /api/classificationexternal/2715 true 2715 true D1 DIRECT true true /api/publication/34484703 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Overbeek Kasper A ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000322"><a href="/gui2/?type=authors&mode=browse&sel=10000322" target="_blank">Czakó László (<span class="authorship-author-name">Czakó László</span> <span class="authorAux-mtmt"> gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/Szentágothai János Kutatóközpont; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002629"><a href="/gui2/?type=authors&mode=browse&sel=10002629" target="_blank">Hegyi Peter (<span class="authorship-author-name">Hegyi Péter</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Szentágothai János Kutatóközpont">SZKK</span>/Transzlációs medicina kutatócsoport; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Pankreász Betegségek Részlege</span> ;&nbsp;&nbsp;&nbsp; et al. (65) </div> <div class="autype autype-29"> Kollaborációs szervezet: <span class="author-affil">the PrescrAIP Study Group</span> </div> <div><a target="_blank" href="/api/publication/34484703?labelLang=hun">Összes szerző</a></div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34484703" target="_blank">Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment</a></div> <div> <span class="journal-title">CLINICAL GASTROENTEROLOGY AND HEPATOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1542-3565">1542-3565</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1542-7714">1542-7714</a>)</span>: <span class="journal-volume">22</span> <span class="journal-issue">5</span> <span class="page"> pp 994-1004.e10 </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1016/j.cgh.2023.12.010" target="_blank" href="https://doi.org/10.1016/j.cgh.2023.12.010"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001241830900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001241830900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85184766789" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85184766789"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38184096" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38184096&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Gastroenterology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Hepatology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 40</span> | Független: 29 | Függő: 11 | Nem jelölt: 0 | WoS jelölt: 38 | Scopus jelölt:&nbsp;34 | WoS/Scopus jelölt:&nbsp;40 | DOI jelölt:&nbsp;39 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34484703&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34484703</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Sokszerzős vagy csoportos szerzőségű szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">PubMed XML</span> </div> <div class="lastModified">Utolsó módosítás: 2025.03.27. 11:18 Berhidi Anna (SE_KK_Admin5_BA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Export Date: 30 March 2025; CODEN: CGHLA</pre> </div></div>