https://m2.mtmt.hu/ hun 2026-09-22 03:53 JournalArticle 34483948 VALIDATED true Department of Dermatology, Venereology and Dermatooncology, Semmelweis University, Budapest, 1085, Hungary Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, 1085, Hungary Export Date: 21 January 2024; Cited By: 0; Correspondence Address: M. Medvecz; Department of Dermatology, Venereology and Dermatooncology, Semmelweis University, Budapest, 1085, Hungary; email: medvecz.marta@med.semmelweis-univ.hu 0 false 2026-08-04T11:24:01.405+0000 2024-01-08T12:22:43.758+0000 2024-01-08T11:51:47.921+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2025-01-28T09:27:28.753+0000 2025-01-28T09:27:28.753+0000 2024-01-08T12:22:43.767+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Palla, Sara Primary Localized Cutaneous Amyloidosis in Central Europe: A Retrospective Monocentric Study on Epidemiology and Therapy true true /api/journal/10017543 REVIEWED true false 10017543 false 10017543 true 2077-0383 Journal FOREIGN 12 24 7672 7672 13 2023 Amyloid deposits can be the cause of many chronic diseases. Primary localized cutaneous amyloidosis (PLCA) is a chronic dermatologic condition with amyloid deposits in the papillary dermis. The most common types of the keratinocyte-derived form of PLCA include macular (MA), lichen (LA), and biphasic (BA) amyloidosis. The estimated prevalence of PLCA in the Asian population is 0.98/10,000, which is higher than in the European population; thus, epidemiologic data on PLCA in the Caucasian population are limited. We performed a retrospective single-center study analyzing epidemiologic characteristics of a Central European PLCA population. Epidemiologic data regarding age, sex, skin phototype (Fitzpatrick scale I-VI), disease duration, comorbidities, history of atopy, and family history of PLCA were collected. Clinical characteristics, localization of PLCA lesions, applied therapies and treatment outcomes were also analyzed. Dermoscopic characteristics were also evaluated. A total of 41 patients diagnosed with PLCA were included, with 22 presenting with macular, 18 with lichen, and 1 with biphasic amyloidosis. The male/female ratio was 16/25, and mean age at diagnosis was 54.6 +/- 15.2 years (range 27-87 years). The mean age at the onset of PLCA was 53 +/- 16.1 years (range 19-79 years) in MA, 46.7 +/- 18.2 years (range 14-73 years) in LA, and 26 years in BA. The interscapular region in MA and the extensor surface of the lower extremities in LA proved to be localization-related areas. In our center, a wide range of therapeutic options was applied, with the most prescribed being topical corticosteroids in all types of PLCA. We presented a retrospective, monocentric study on the epidemiology of PLCA in the Central European region. By examining the medical data of a significant number of PLCA patients, we compared our epidemiologic data with that of the Asian PLCA population. Due to the rarity of the condition, further randomized controlled trials and guidelines are needed to improve therapeutic outcomes. Funding 2035245 /api/funding/2035245 false true Funding 2035246 /api/funding/2035246 false true true 2024 true true true false true false GOLD 2026-08-04 false http://www.mdpi.com/journal/jcm 10 0 10 9 1 10 10 10 8 10 10 9 9 9 1 0 10 9 10 9 0 3 3 Folyóiratcikk Journal Article 24 10 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 5 5 5 5 2025 0 2 2 2 2 2026 0 3 2 3 2 Q1 false false false false 2024-01-07T12:22:43.579+0000 Bőr-, Nemikórtani és Bőronkológiai Klinika (SE / AOK / K); Patológiai és Kísérleti Rákkutató Intézet (SE / AOK / I) 5 15 2 6 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 113699490 /api/authorship/113699490 1 0.167 true false false Author 10074254 /api/author/10074254 Pálla Sára Judit true true Palla Sara true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113699491 /api/authorship/113699491 2 0.167 false false false Author 10069048 /api/author/10069048 Kuroli Enikő true true Kuroli Eniko true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113699492 /api/authorship/113699492 3 0.16666667 false false false Toth Eszter Alexa true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113699493 /api/authorship/113699493 4 0.167 false false false Author 10024595 /api/author/10024595 Hidvégi Bernadett true 10024595 true Hidvegi Bernadett true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113699494 /api/authorship/113699494 5 0.167 false false false Author 10019467 /api/author/10019467 Holló Péter true 10019467 true Hollo Peter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113699495 /api/authorship/113699495 6 0.167 false true true Author 10012260 /api/author/10012260 Medvecz Márta true 10012260 true Medvecz Marta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 25246366 /api/publicationidentifier/25246366 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.3390/jcm12247672 https://doi.org/10.3390/jcm12247672 false true PublicationIdentifier 25246367 /api/publicationidentifier/25246367 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001130851800001 https://www.webofscience.com/wos/woscc/full-record/001130851800001 false true PublicationIdentifier 25246369 /api/publicationidentifier/25246369 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85180703005 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85180703005 false true PublicationIdentifier 25246368 /api/publicationidentifier/25246368 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38137741 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38137741&dopt=Abstract false true Keyword 280 /api/keyword/280 true 280 true Keyword 595 /api/keyword/595 true 595 true Keyword 623 /api/keyword/623 true 623 true Keyword 5674 /api/keyword/5674 true 5674 true Keyword 10097 /api/keyword/10097 true 10097 true Keyword 12792 /api/keyword/12792 true 12792 true Keyword 19957 /api/keyword/19957 true 19957 true Keyword 1011740 /api/keyword/1011740 true 1011740 true Keyword 1012553 /api/keyword/1012553 true 1012553 true Keyword 1012929 /api/keyword/1012929 true 1012929 true Keyword 1020045 /api/keyword/1020045 true 1020045 true Keyword 1029034 /api/keyword/1029034 true 1029034 true Keyword 1036693 /api/keyword/1036693 true 1036693 true Keyword 1096542 /api/keyword/1096542 true 1096542 true Keyword 1435948 /api/keyword/1435948 true 1435948 true Keyword 3279098 /api/keyword/3279098 true true Keyword 3279098 /api/keyword/3279098 true true Keyword 3279100 /api/keyword/3279100 true true Keyword 3279100 /api/keyword/3279100 true true SjrRating 11397327 /api/sjrrating/11397327 614 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true Q1 DIRECT true true /api/publication/34483948 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10074254"><a href="/gui2/?type=authors&mode=browse&sel=10074254" target="_blank">Palla Sara (<span class="authorship-author-name">Pálla Sára Judit</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10069048"><a href="/gui2/?type=authors&mode=browse&sel=10069048" target="_blank">Kuroli Eniko (<span class="authorship-author-name">Kuroli Enikő</span> <span class="authorAux-mtmt"> bőrgyógyászat, patológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Patológiai és Kísérleti Rákkutató Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Toth Eszter Alexa </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024595"><a href="/gui2/?type=authors&mode=browse&sel=10024595" target="_blank">Hidvegi Bernadett (<span class="authorship-author-name">Hidvégi Bernadett</span> <span class="authorAux-mtmt"> bőrgyógyászat allergoimmunológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10019467"><a href="/gui2/?type=authors&mode=browse&sel=10019467" target="_blank">Hollo Peter (<span class="authorship-author-name">Holló Péter</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012260"><a href="/gui2/?type=authors&mode=browse&sel=10012260" target="_blank">Medvecz Marta ✉ (<span class="authorship-author-name">Medvecz Márta</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34483948" target="_blank">Primary Localized Cutaneous Amyloidosis in Central Europe: A Retrospective Monocentric Study on Epidemiology and Therapy</a></div> <div> <span class="journal-title">JOURNAL OF CLINICAL MEDICINE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2077-0383">2077-0383</a>)</span>: <span class="journal-volume">12</span> <span class="journal-issue">24</span> <span class="page"> Paper 7672. 13 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3390/jcm12247672" target="_blank" href="https://doi.org/10.3390/jcm12247672"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001130851800001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001130851800001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85180703005" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85180703005"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38137741" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38137741&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 10</span> | Független: 9 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 10 | Scopus jelölt:&nbsp;8 | WoS/Scopus jelölt:&nbsp;10 | DOI jelölt:&nbsp;10 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34483948&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34483948</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="funder"> (FK131916), Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009) Támogató: EFOP-VEKOP </div> <div class="lastModified">Utolsó módosítás: 2024.01.08. 13:22 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Dermatology, Venereology and Dermatooncology, Semmelweis University, Budapest, 1085, Hungary Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, 1085, Hungary Export Date: 21 January 2024; Cited By: 0; Correspondence Address: M. Medvecz; Department of Dermatology, Venereology and Dermatooncology...</pre> </div></div>