https://m2.mtmt.hu/ hun 2026-09-21 05:43 JournalArticle 34481244 VALIDATED true 0 false 2026-09-17T07:51:32.186+0000 2024-05-17T07:37:09.250+0000 2024-01-06T16:18:16.632+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 2024-05-17T07:36:35.628+0000 2024-05-17T07:36:35.628+0000 2024-05-17T07:37:09.262+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true Admin 10025544 /api/admin/10025544 Lévayné Deseő Katalin true 10025544 true 2025-06-04T23:42:20.612+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType 104 true 10000359 true 1 /api/category/1 Category true 1 Oliver, Antonio Pseudomonas aeruginosa antimicrobial susceptibility profiles, resistance mechanisms and international clonal lineages update from ESGARS-ESCMID/ISARPAE Group. true true /api/journal/10000627 REVIEWED true false 10000627 false 10000627 true 1198-743X 1469-0691 Journal FOREIGN 30 4 469 480 469 12 2024 Pseudomonas aeruginosa, a ubiquitous opportunistic pathogen considered one of the paradigms of antimicrobial resistance, is among the main causes of hospital-acquired and chronic infections associated with significant morbidity and mortality. This growing threat results from the extraordinary capacity of P. aeruginosa to develop antimicrobial resistance through chromosomal mutations, the increasing prevalence of transferable resistance determinants (such as the carbapenemases and the extended spectrum β-lactamases), and the global expansion of epidemic lineages. The general objective of this initiative is to provide a comprehensive update of P. aeruginosa resistance mechanisms, especially for the extensively drug-resistant (XDR)/difficult to treat resistance (DTR) international high-risk epidemic lineages, and how the recently approved β-lactams and β-lactam/β-lactamase inhibitor combinations may affect resistance mechanisms and the definition of susceptibility profiles.To address this challenge, the European Study Group for Antimicrobial Resistance Surveillance (ESGARS) from the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) launched the "Improving Surveillance of Antibiotic-Resistant Pseudomonas aeruginosa in Europe" (ISARPAE) initiative in 2022, supported by the Joint programming initiative on antimicrobial resistance (JPIAMR) network call and included a panel of over 40 researchers from 18 European Countries. Thus, an ESGARS-ISARPAE position paper was designed and the final version agreed after four rounds of revision and discussion by all panel members.To provide an update on (i) the emerging resistance mechanisms to classical and novel antipseudomonal agents, with a particular focus on β-lactams, (ii) the susceptibility profiles associated with the most relevant β-lactam resistance mechanisms, (iii) the impact of the novel agents and resistance mechanisms on the definitions of resistance profiles and (iv) the globally expanding XDR/DTR high-risk lineages and their association with transferable resistance mechanisms.The evidence presented herein can be used for coordinated epidemiological surveillance and decision-making at the European and global level. 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src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Oliver Antonio ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10021933"><a href="/gui2/?type=authors&mode=browse&sel=10021933" target="_blank">Kocsis Béla (<span class="authorship-author-name">Kocsis Béla</span> <span class="authorAux-mtmt"> mikrobiológia (Semmelweis Egyetem)</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Orvosi Mikrobiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10003357"><a href="/gui2/?type=authors&mode=browse&sel=10003357" target="_blank">Szabó Dora (<span class="authorship-author-name">Szabó Dóra</span> <span class="authorAux-mtmt"> Mikrobiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Orvosi Mikrobiológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Orvosi Mikrobiológiai Intézet">OMI</span>/ELKH-SE Humán Mikrobiota Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; et al. (35) </div> <div class="autype autype-29"> Kollaborációs szervezet: <span class="author-affil">ESGARS-ISARPAE members</span> </div> <div><a target="_blank" href="/api/publication/34481244?labelLang=hun">Összes szerző</a></div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34481244" target="_blank">Pseudomonas aeruginosa antimicrobial susceptibility profiles, resistance mechanisms and international clonal lineages : update from ESGARS-ESCMID/ISARPAE Group..</a></div> <div> <span class="journal-title">CLINICAL MICROBIOLOGY AND INFECTION</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1198-743X">1198-743X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1469-0691">1469-0691</a>)</span>: <span class="journal-volume">30</span> <span class="journal-issue">4</span> <span class="page"> pp 469-480 </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1016/j.cmi.2023.12.026" target="_blank" href="https://doi.org/10.1016/j.cmi.2023.12.026"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001215550400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001215550400001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="205304" target="_blank" href="https://real.mtak.hu/205304"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85182993342" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85182993342"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38160753" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38160753&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Infectious Diseases&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Microbiology (medical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 105</span> | Független: 81 | Függő: 24 | Nem jelölt: 0 | WoS jelölt: 93 | Scopus jelölt:&nbsp;99 | WoS/Scopus jelölt:&nbsp;104 | DOI jelölt:&nbsp;104 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34481244</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Sokszerzős vagy csoportos szerzőségű szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (BO/00286/22/5) </div> <div class="lastModified">Utolsó módosítás: 2024.05.17. 09:37 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <div class="lockedBy">Központi kezelésű 2025.06.05. 01:42 Lévayné Deseő Katalin (MTMT Központi admin) </div> </div></div>