https://m2.mtmt.hu/ eng 2026-05-31 09:16 JournalArticle 34450797 VALIDATED true 0 false 2026-05-23T11:07:12.115+0000 2024-08-07T06:54:29.344+0000 2023-12-27T10:45:12.392+0000 true 10081340 Pirmann Tamás /api/admin/10081340 Admin true 2025-09-01T11:10:38.832+0000 2024-08-07T06:54:29.510+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 Admin 10067876 /api/admin/10067876 Ladányi Gusztáv true true Admin 10080105 /api/admin/10080105 Kériné Tornyi Katalin true true 2024-10-17T16:16:12.275+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Bukovszky, Botond Neck Node Squamous Cell Metastasis from Unknown Primary and Mutagen Sensitivity A Case Series true true /api/journal/10049428 REVIEWED true false 10049428 false 10049428 true 1662-6575 1662-6575 Journal FOREIGN 16 1 1598 1605 1598 8 2023 Most of the neck node metastases from cancer of unknown primary (CUP) are squamous cell carcinomas (SCCs). The majority of which are human papillomavirus (HPV)-related, frequently show cystic morphology referring to Waldeyer's ring origin. Here, we report four cases of neck node SCCs metastases from CUP. In our institute, 432 patients with head and neck (HN) SCC underwent pretreatment mutagen sensitivity (MS) assay between 1996 and 2006. Among them, 4 patients ≤50 years of age had metastatic cervical nodes from CUP. The primary treatment was cervical node dissection ± radiotherapy. All patients had elevated (>1.0 chromatid break/cell) MS. One male patient died of progressive neck metastasis within 3 years and the 3 female patients are still alive more than 15 years after initial treatment of HPV+ (two) or cystic (one) SCC. Two female patients developed second and third distant site metachronous primary cancers. HPV+ or cystic HNSCC from CUP with elevated MS indicates good outcome. Distant site metachronous cancers of different histologic origins cannot be explained by field cancerization. The clinical significance of elevated MS in neck node SCC metastasis from CUP requires further investigation. true true 2023 true true true false true false GOLD 2026-05-23 false https://www.karger.com/CRO 1 0 1 1 0 1 1 1 1 1 1 1 1 1 0 0 1 1 1 1 0 4 4 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 1 1 1 1 Q3 false false false false 2024-03-26T10:45:16.390+0000 Onkológiai Tanszék (SE / AOK / K); Országos Onkológiai Intézet; Orális Diagnosztikai Tanszék (SE / FOK) 8 14 3 8 0 true 10080105 10067876 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 113424287 /api/authorship/113424287 1 0.125 true false true Author 10080431 /api/author/10080431 Bukovszky Botond true true Bukovszky Botond true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113424288 /api/authorship/113424288 2 0.125 false false false Author 10003193 /api/author/10003193 Fodor János true 10003193 true Fodor János true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113424289 /api/authorship/113424289 3 0.125 false false false Author 10032265 /api/author/10032265 Székely Gábor true 10032265 true Székely Gábor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113424290 /api/authorship/113424290 4 0.125 false false false Author 10062288 /api/author/10062288 Tóth Erika true 10062288 true Tóth Erika true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113424291 /api/authorship/113424291 5 0.125 false false false Author 10044386 /api/author/10044386 Major Tibor true 10044386 true Major Tibor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113424292 /api/authorship/113424292 6 0.125 false false false Author 10044886 /api/author/10044886 Oberna Ferenc true 10044886 true Oberna Ferenc true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113424293 /api/authorship/113424293 7 0.125 false false false Author 10013883 /api/author/10013883 Takácsi-Nagy Zoltán true 10013883 true Takácsi-Nagy Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113424294 /api/authorship/113424294 8 0.125 false true false Author 10013383 /api/author/10013383 Polgár Csaba true 10013383 true Polgár Csaba true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 25140612 /api/publicationidentifier/25140612 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1159/000533708 https://doi.org/10.1159/000533708 false true PublicationIdentifier 26910116 /api/publicationidentifier/26910116 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001203472100217 https://www.webofscience.com/wos/woscc/full-record/001203472100217 true true PublicationIdentifier 25266384 /api/publicationidentifier/25266384 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85180995005 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85180995005 false true PublicationIdentifier 25140611 /api/publicationidentifier/25140611 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 38116298 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38116298&dopt=Abstract false true Keyword 1977099 /api/keyword/1977099 true true Keyword 3266779 /api/keyword/3266779 true true Keyword 3266780 /api/keyword/3266780 true true Keyword 3266781 /api/keyword/3266781 true true SjrRating 11403894 /api/sjrrating/11403894 282 0.74 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2730 /api/classificationexternal/2730 true 2730 true Q3 DIRECT true true /api/publication/34450797 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10080431"><a href="/gui2/?type=authors&mode=browse&sel=10080431" target="_blank">Bukovszky Botond ✉ (<span class="authorship-author-name">Bukovszky Botond</span> <span class="authorAux-mtmt"> Dento-alveolaris sebészet</span>) </a> </span> <span class="author-affil">National Institute of Oncology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Dentistry">FD</span>/Department of Oral Diagnosics; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10003193"><a href="/gui2/?type=authors&mode=browse&sel=10003193" target="_blank">Fodor János (<span class="authorship-author-name">Fodor János</span> <span class="authorAux-mtmt"> Orvosi tudomány</span>) </a> </span> <span class="author-affil">National Institute of Oncology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10032265"><a href="/gui2/?type=authors&mode=browse&sel=10032265" target="_blank">Székely Gábor (<span class="authorship-author-name">Székely Gábor</span> <span class="authorAux-mtmt"> genetika</span>) </a> </span> <span class="author-affil">National Institute of Oncology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10062288"><a href="/gui2/?type=authors&mode=browse&sel=10062288" target="_blank">Tóth Erika (<span class="authorship-author-name">Tóth Erika</span> <span class="authorAux-mtmt"> patológia</span>) </a> </span> <span class="author-affil">National Institute of Oncology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10044386"><a href="/gui2/?type=authors&mode=browse&sel=10044386" target="_blank">Major Tibor (<span class="authorship-author-name">Major Tibor</span> <span class="authorAux-mtmt"> klinikai sugárfizika</span>) </a> </span> <span class="author-affil">National Institute of Oncology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10044886"><a href="/gui2/?type=authors&mode=browse&sel=10044886" target="_blank">Oberna Ferenc (<span class="authorship-author-name">Oberna Ferenc</span> <span class="authorAux-mtmt"> Arc- és állcsontsebészet, fül-orr-gégészet</span>) </a> </span> <span class="author-affil">National Institute of Oncology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013883"><a href="/gui2/?type=authors&mode=browse&sel=10013883" target="_blank">Takácsi-Nagy Zoltán (<span class="authorship-author-name">Takácsi-Nagy Zoltán</span> <span class="authorAux-mtmt"> Sugárterápia</span>) </a> </span> <span class="author-affil">National Institute of Oncology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013383"><a href="/gui2/?type=authors&mode=browse&sel=10013383" target="_blank">Polgár Csaba (<span class="authorship-author-name">Polgár Csaba</span> <span class="authorAux-mtmt"> Sugárterápia, klinikai onkológia</span>) </a> </span> <span class="author-affil">National Institute of Oncology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Onkológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34450797" target="_blank">Neck Node Squamous Cell Metastasis from Unknown Primary and Mutagen Sensitivity : A Case Series.</a></div> <div> <span class="journal-title">CASE REPORTS IN ONCOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1662-6575">1662-6575</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1662-6575">1662-6575</a>)</span>: <span class="journal-volume">16</span> <span class="journal-issue">1</span> <span class="page"> pp 1598-1605 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1159/000533708" target="_blank" href="https://doi.org/10.1159/000533708"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001203472100217" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001203472100217"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85180995005" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85180995005"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38116298" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38116298&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Oncology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 1</span> | Independent citation: 1 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 1 | Number of citations in Scopus:&nbsp;1 | WoS/Scopus assigned:&nbsp;1 | Number of citations with DOI:&nbsp;1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34450797&sort=publishedYear,desc&sort=title"> Number of cited publications: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 34450797</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Last Modified: 2024.08.07. 08:54 Márta Molnár-Taga (SE 4-es admin) </div> <div class="lockedBy">Centrally managed 2024.10.17. 18:16 Gusztáv Ladányi (MTMT API user, admin) Katalin Kériné Tornyi (MTMT ellenőrzés admin5) </div> </div></div>