https://m2.mtmt.hu/ hun 2026-09-22 20:38 JournalArticle 34437476 VALIDATED true 0 false 2026-09-16T09:05:08.060+0000 2026-09-16T07:27:05.291+0000 2023-12-15T13:24:46.345+0000 true 10078148 Havas Petra /api/admin/10078148 Admin true 2026-05-07T09:21:35.287+0000 2026-05-07T09:21:35.287+0000 2026-09-16T07:27:05.300+0000 true 10069305 Kondor Zóra /api/admin/10069305 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Bolla, Gergo Comparison of the diagnostic accuracy of resting-state fMRI driven machine learning algorithms in the detection of mild cognitive impairment. true true /api/journal/10019966 REVIEWED true false 10019966 false 10019966 true 2045-2322 Journal FOREIGN 13 1 22285 22285 16 2023 Mild cognitive impairment (MCI) is a potential therapeutic window in the prevention of dementia; however, automated detection of early cognitive deterioration is an unresolved issue. The aim of our study was to compare various classification approaches to differentiate MCI patients from healthy controls, based on rs-fMRI data, using machine learning (ML) algorithms. Own dataset (from two centers) and ADNI database were used during the analysis. Three fMRI parameters were applied in five feature selection algorithms: local correlation, intrinsic connectivity, and fractional amplitude of low frequency fluctuations. Support vector machine (SVM) and random forest (RF) methods were applied for classification. We achieved a relatively wide range of 78-87% accuracy for the various feature selection methods with SVM combining the three rs-fMRI parameters. In the ADNI datasets case we can also see even 90% accuracy scores. RF provided a more harmonized result among the feature selection algorithms in both datasets with 80-84% accuracy for our local and 74-82% for the ADNI database. Despite some lower performance metrics of some algorithms, most of the results were positive and could be seen in two unrelated datasets which increase the validity of our methods. Our results highlight the potential of ML-based fMRI applications for automated diagnostic techniques to recognize MCI patients. Funding 2034891 /api/funding/2034891 false true Funding 2034892 /api/funding/2034892 false true Funding 2034893 /api/funding/2034893 false true Funding 2034894 /api/funding/2034894 false true Funding 2034895 /api/funding/2034895 false true true 2023 true true true false true false GOLD 2026-09-16 false http://www.nature.com/srep/index.html 19 0 19 18 1 19 18 13 15 17 17 16 16 18 1 0 19 18 19 18 0 0 0 Folyóiratcikk Journal Article 24 13 Könyvrészlet Chapter in Book 25 5 Könyv Book 23 1 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 7 7 7 7 2025 0 7 7 7 7 2026 0 4 3 4 3 D1 A nemzetközi false 10084272 false false false 2023-12-27T11:57:52.048+0000 Amerikai úti Ideggyógyászati és Idegsebészeti I... (OMIII); Anatómiai, Szövet- és Fejlődéstani Intézet (SE / AOK / I); Családorvosi Tanszék (SE / AOK / K); Doktori Iskola (SE); Neurológiai Klinika (SE / AOK / K); Pszichiátriai és Pszichoterápiás Klinika (SE / AOK / K) 8 29 6 10 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 113273051 /api/authorship/113273051 1 0.1 true false false Author 10092972 /api/author/10092972 Bolla Gergő Levente true true Bolla Gergo true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273052 /api/authorship/113273052 2 0.1 false false false Author 10083416 /api/author/10083416 Berente Dalida Borbála true true Berente Dalida Borbala true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273053 /api/authorship/113273053 3 0.1 false false false Author 10089476 /api/author/10089476 Andrássy Anita true true Andrássy Anita true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273054 /api/authorship/113273054 4 0.1 false false false Author 10084272 /api/author/10084272 Zsuffa János true true Zsuffa Janos Andras true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273055 /api/authorship/113273055 5 0.1 false false false Author 10023957 /api/author/10023957 Hidasi Zoltán true 10023957 true Hidasi Zoltan true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273056 /api/authorship/113273056 6 0.1 false false false Csibri Eva true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273057 /api/authorship/113273057 7 0.1 false false false Author 10023954 /api/author/10023954 Csukly Gábor true 10023954 true Csukly Gabor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273058 /api/authorship/113273058 8 0.1 false false false Author 10000108 /api/author/10000108 Kamondi Anita true 10000108 true Kamondi Anita true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273059 /api/authorship/113273059 9 0.1 false false false Kiss Mate true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113273060 /api/authorship/113273060 10 0.1 false true true Author 10055054 /api/author/10055054 Horváth András Attila true 10055054 true Horvath Andras Attila true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 25111503 /api/publicationidentifier/25111503 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1038/s41598-023-49461-y https://doi.org/10.1038/s41598-023-49461-y false true PublicationIdentifier 25812422 /api/publicationidentifier/25812422 PlainSource 1 /api/publicationsource/1 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/api/publication/34437476 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10092972"><a href="/gui2/?type=authors&mode=browse&sel=10092972" target="_blank">Bolla Gergo (<span class="authorship-author-name">Bolla Gergő Levente</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/Doktori Iskola; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Amerikai úti Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10083416"><a href="/gui2/?type=authors&mode=browse&sel=10083416" target="_blank">Berente Dalida Borbala (<span class="authorship-author-name">Berente Dalida Borbála</span> <span class="authorAux-mtmt"> Orvosi tudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/Doktori Iskola; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Amerikai úti Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10089476"><a href="/gui2/?type=authors&mode=browse&sel=10089476" target="_blank">Andrássy Anita (<span class="authorship-author-name">Andrássy Anita</span> <span class="authorAux-mtmt"> neuroradiológia</span>) </a> </span> <span class="author-affil"><span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Amerikai úti Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10084272"><a href="/gui2/?type=authors&mode=browse&sel=10084272" target="_blank">Zsuffa Janos Andras (<span class="authorship-author-name">Zsuffa János</span> <span class="authorAux-mtmt"> Háziorvostan</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Családorvosi Tanszék; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Amerikai úti Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023957"><a href="/gui2/?type=authors&mode=browse&sel=10023957" target="_blank">Hidasi Zoltan (<span class="authorship-author-name">Hidasi Zoltán</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Csibri Eva </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023954"><a href="/gui2/?type=authors&mode=browse&sel=10023954" target="_blank">Csukly Gabor (<span class="authorship-author-name">Csukly Gábor</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Amerikai úti Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000108"><a href="/gui2/?type=authors&mode=browse&sel=10000108" target="_blank">Kamondi Anita (<span class="authorship-author-name">Kamondi Anita</span> <span class="authorAux-mtmt"> Idegtudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Neurológiai Klinika; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Amerikai úti Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kiss Mate </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10055054"><a href="/gui2/?type=authors&mode=browse&sel=10055054" target="_blank">Horvath Andras Attila ✉ (<span class="authorship-author-name">Horváth András Attila</span> <span class="authorAux-mtmt"> neurológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Anatómiai, Szövet- és Fejlődéstani Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34437476" target="_blank">Comparison of the diagnostic accuracy of resting-state fMRI driven machine learning algorithms in the detection of mild cognitive impairment.</a></div> <div> <span class="journal-title">SCIENTIFIC REPORTS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2045-2322">2045-2322</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">1</span> <span class="page"> Paper 22285. 16 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1038/s41598-023-49461-y" target="_blank" href="https://doi.org/10.1038/s41598-023-49461-y"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001125340600075" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001125340600075"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85179679815" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85179679815"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38097674" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38097674&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Multidisciplinary&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Szociológiai Tudományos Bizottság IXGJO SZTB [1901-]&nbsp;&nbsp;&nbsp;A nemzetközi</div> <div class="journal-subject">Regionális Tudományok Bizottsága IXGJO RTB [1901-]&nbsp;&nbsp;&nbsp;B nemzetközi</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 19</span> | Független: 18 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 13 | Scopus jelölt:&nbsp;15 | WoS/Scopus jelölt:&nbsp;17 | DOI jelölt:&nbsp;18 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34437476</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> Hungarian National Brain Research Program(2017-1.2.1-NKP-2017-00002), Hungarian Brain Research Program(NAP2022-I-9/2022), (bo_78_20_2020) Támogató: Bolyai János Kutatási Ösztöndíj, (Lendulet-2023_94), (2019-2.1.7-ERA-NET-2020-00006) Támogató: NKFI </div> <div class="lastModified">Utolsó módosítás: 2026.09.16. 09:27 Kondor Zóra (SE_KK_Admin5_KZ, admin) </div> </div></div>