(TKP2021-EGA-23) Funder: Ministry for Innovation and Technology
(K131996)
(KA-2019-14)
(FK131864)
(UNKP-22-5)
Establishing the Hungarian Center of Excellence for Molecular Medicine in partnership
with EMBL(739593) Funder: Horizon 2020
(BO/00648/21/5)
(ÚNKP-22-4-II.)
Subjects:
Gastroenterology and hepatology
MEDICAL AND HEALTH SCIENCES
There are several overlapping clinical practice guidelines in acute pancreatitis (AP),
however, none of them contains suggestions on patient discharge. The Hungarian Pancreatic
Study Group (HPSG) has recently developed a laboratory data and symptom-based discharge
protocol which needs to be validated. (1) A survey was conducted involving all members
of the International Association of Pancreatology (IAP) to understand the characteristics
of international discharge protocols. (2) We investigated the safety and effectiveness
of the HPSG-discharge protocol. According to our international survey, 87.5% (49/56)
of the centres had no discharge protocol. Patients discharged based on protocols have
a significantly shorter median length of hospitalization (LOH) (7 (5;10) days vs.
8 (5;12) days) p < 0.001), and a lower rate of readmission due to recurrent AP episodes
(p = 0.005). There was no difference in median discharge CRP level among the international
cohorts (p = 0.586). HPSG-protocol resulted in the shortest LOH (6 (5;9) days) and
highest median CRP (35.40 (13.78; 68.40) mg/l). Safety was confirmed by the low rate
of readmittance (n = 35; 5%). Discharge protocol is necessary in AP. The discharge
protocol used in this study is the first clinically proven protocol. Developing and
testifying further protocols are needed to better standardize patients' care.
