https://m2.mtmt.hu/ hun 2026-09-20 16:05 JournalArticle 34415084 VALIDATED true 0 false 2026-07-29T07:56:57.712+0000 2026-02-19T14:14:18.838+0000 2023-12-05T07:50:43.042+0000 true 10070075 Nádas Orsolya /api/admin/10070075 Admin true 2026-02-19T14:14:19.085+0000 2026-02-19T14:14:19.085+0000 2024-02-10T19:54:05.953+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true Admin 10065569 /api/admin/10065569 Pécsi Éva true true 2026-02-06T10:56:21.970+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Ferenczi, Örs Dosimetric comparison of postoperative interstitial high-dose-rate brachytherapy and modern external beam radiotherapy modalities in tongue and floor of the mouth tumours in terms of doses to critical organs true true /api/journal/10013541 REVIEWED true false 10013541 false 10013541 true 1318-2099 1581-3207 Journal FOREIGN 57 4 516 523 516 8 2023 The aim of the study was to dosimetrically compare interstitial high-dose-rate (HDR) brachytherapy (BT) and modern external beam radiotherapy modalities, as volumetric modulated arc therapy (VMAT) and stereotactic radiotherapy with Cyberknife (CK) of tumours of the tongue and floor of the mouth in terms of dose to the critical organs.In National Institute of Oncology, Budapest, between March 2013 and August 2022 twenty patients (11 male/9 female) with stage T1-3N0M0 tongue (n = 14) and floor of mouth (n = 6) tumours received postoperative radiotherapy because of close/positive surgical margin and/or lymphovascular and/or perineural invasion. High-dose-rate interstitial brachytherapy applying flexible plastic catheters with a total dose of 15 × 3 Gy was used for treatment. In addition to BT plans VMAT and stereotactic CK plans were also made in all cases, using the same fractionation scheme and dose prescription. As for the organs at risk, the doses to the mandible, the ipsilateral and the contralateral salivary glands were compared.The mean volume of the planning target volume (PTV) was 12.5 cm3, 26.5 cm3 and 17.5 cm3 in BT, VMAT and CK techniques, respectively, due to different safety margin protocols. The dose to the mandible was the most favourable with BT, as for the salivary glands (parotid and submandibular) the CK technique resulted in the lowest dose. The highest dose to the critical organs was observed with the VMAT technique. The mean values of D2cm3 and D0.1cm3 for the critical organs were as follows for BT, VMAT and CK plans: 47.4% and 73.9%, 92.2% and 101.8%, 68.4% and 92.3% for the mandible, 4.8% and 6.7%, 7.3% and 13.8%, 2.3% and 5.1% for the ipsilateral parotid gland, 3.5% and 4.9%, 6.8% and 10.9%, 1.5% and 3.3% for the contralateral parotid gland, 7.3% and 9.4%, 9.0% and 14.3%, 3.6% and 5.6% for the contralateral submandibular gland.The present results confirm that BT, despite being an invasive technique, is dosimetrically clearly beneficial in the treatment of oral cavity tumours and is a modality worth considering when applying radiotherapy, not only as definitive treatment, but also postoperatively. The use of the CK in the head and neck region requires further investigation. Funding 2034112 /api/funding/2034112 false true Funding 2034113 /api/funding/2034113 false true true NATIONAL 2023 true true true false true false GOLD 2026-07-29 true https://doi.org/10.2478/raon-2023-0050 5 0 5 3 2 5 5 5 5 5 5 3 3 3 2 0 5 3 5 3 0 5 5 Folyóiratcikk Journal Article 24 5 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 2 2 2 2 2025 0 2 1 2 1 2026 0 1 0 1 0 Q2 false 10044386,10016868 false false false 2023-12-10T11:37:17.702+0000 Biológiai Fizika Tanszék (ELTE / TTK / FizCsill_I); Onkológiai Tanszék (SE / AOK / K); Országos Onkológiai Intézet; Orális Diagnosztikai Tanszék (SE / FOK) 8 21 4 9 0 true 10065569 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 113122307 /api/authorship/113122307 1 0.111 true false true Author 10085309 /api/author/10085309 Ferenczi Örs true true Ferenczi Örs true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113122308 /api/authorship/113122308 2 0.111 false false false Author 10044386 /api/author/10044386 Major Tibor true 10044386 true Major Tibor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113122309 /api/authorship/113122309 3 0.111 false false false Author 10016868 /api/author/10016868 Fröhlich Georgina true 10016868 true Fröhlich Georgina true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113122310 /api/authorship/113122310 4 0.111 false false false Author 10065843 /api/author/10065843 Mihály Dalma true true Béla Dalma true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113122311 /api/authorship/113122311 5 0.111 false false false Author 10065842 /api/author/10065842 Tódor István Szabolcs true true Tódor Szabolcs true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113122312 /api/authorship/113122312 6 0.111 false false false Author 10013383 /api/author/10013383 Polgár Csaba true 10013383 true Polgár Csaba true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113122313 /api/authorship/113122313 7 0.11111111 false false false Akiyama Hironori true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113122314 /api/authorship/113122314 8 0.111 false false false Author 10080431 /api/author/10080431 Bukovszky Botond true true Bukovszky Botond true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 113122315 /api/authorship/113122315 9 0.111 false true false Author 10013883 /api/author/10013883 Takácsi-Nagy Zoltán true 10013883 true Takácsi-Nagy Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 25060839 /api/publicationidentifier/25060839 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.2478/raon-2023-0050 https://doi.org/10.2478/raon-2023-0050 false true PublicationIdentifier 25457188 /api/publicationidentifier/25457188 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS 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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38038418&dopt=Abstract false true Classification 12306 /api/classification/12306 true true Keyword 19760 /api/keyword/19760 true 19760 true Keyword 1029741 /api/keyword/1029741 true 1029741 true Keyword 1464008 /api/keyword/1464008 true 1464008 true Keyword 1561981 /api/keyword/1561981 true true Keyword 1640015 /api/keyword/1640015 true true Keyword 1698445 /api/keyword/1698445 true true Keyword 3262758 /api/keyword/3262758 true true Keyword 3262759 /api/keyword/3262759 true true SjrRating 11412447 /api/sjrrating/11412447 133 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2741 /api/classificationexternal/2741 true 2741 true Q2 DIRECT true true /api/publication/34415084 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10085309"><a href="/gui2/?type=authors&mode=browse&sel=10085309" target="_blank">Ferenczi Örs ✉ (<span class="authorship-author-name">Ferenczi Örs</span> <span class="authorAux-mtmt"> Sugárterápia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10044386"><a href="/gui2/?type=authors&mode=browse&sel=10044386" target="_blank">Major Tibor (<span class="authorship-author-name">Major Tibor</span> <span class="authorAux-mtmt"> klinikai sugárfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016868"><a href="/gui2/?type=authors&mode=browse&sel=10016868" target="_blank">Fröhlich Georgina (<span class="authorship-author-name">Fröhlich Georgina</span> <span class="authorAux-mtmt"> Sugárfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Eötvös Loránd Tudományegyetem">ELTE</span>/<span title="Természettudományi Kar">TTK</span>/<span title="Fizikai és Csillagászati Intézet">FizCsill_I</span>/Biológiai Fizika Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065843"><a href="/gui2/?type=authors&mode=browse&sel=10065843" target="_blank">Béla Dalma (<span class="authorship-author-name">Mihály Dalma</span> <span class="authorAux-mtmt"> Klinikai sugárfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065842"><a href="/gui2/?type=authors&mode=browse&sel=10065842" target="_blank">Tódor Szabolcs (<span class="authorship-author-name">Tódor István Szabolcs</span> <span class="authorAux-mtmt"> Klinikai sugárfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013383"><a href="/gui2/?type=authors&mode=browse&sel=10013383" target="_blank">Polgár Csaba (<span class="authorship-author-name">Polgár Csaba</span> <span class="authorAux-mtmt"> Sugárterápia, klinikai onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Akiyama Hironori </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10080431"><a href="/gui2/?type=authors&mode=browse&sel=10080431" target="_blank">Bukovszky Botond (<span class="authorship-author-name">Bukovszky Botond</span> <span class="authorAux-mtmt"> Dento-alveolaris sebészet</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Fogorvostudományi Kar">FOK</span>/Orális Diagnosztikai Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013883"><a href="/gui2/?type=authors&mode=browse&sel=10013883" target="_blank">Takácsi-Nagy Zoltán (<span class="authorship-author-name">Takácsi-Nagy Zoltán</span> <span class="authorAux-mtmt"> Sugárterápia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34415084" target="_blank">Dosimetric comparison of postoperative interstitial high-dose-rate brachytherapy and modern external beam radiotherapy modalities in tongue and floor of the mouth tumours in terms of doses to critical organs</a></div> <div> <span class="journal-title">RADIOLOGY AND ONCOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1318-2099">1318-2099</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1581-3207">1581-3207</a>)</span>: <span class="journal-volume">57</span> <span class="journal-issue">4</span> <span class="page"> pp 516-523 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.2478/raon-2023-0050" target="_blank" href="https://doi.org/10.2478/raon-2023-0050"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001111445200010" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001111445200010"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85178515945" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85178515945"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38038418" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38038418&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Radiology, Nuclear Medicine and Imaging&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Oncology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 5</span> | Független: 3 | Függő: 2 | Nem jelölt: 0 | WoS jelölt: 5 | Scopus jelölt:&nbsp;5 | WoS/Scopus jelölt:&nbsp;5 | DOI jelölt:&nbsp;5 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34415084&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 5 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34415084</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (National Tumor Biology Laboratory project—2022-2.1.1-NL-2022-00010), Hungarian Thematic Excellence Program((TKP2021-EGA-44)) </div> <div class="lastModified">Utolsó módosítás: 2026.02.19. 15:14 Balázs András (MTMT Központ, admin) </div> <div class="lockedBy">Központi kezelésű 2026.02.06. 11:56 Pécsi Éva (MTMT Közp 2,3, admin) </div> </div></div>